1er août

Kidney Int http://www.kidney-international.org/

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  Table of Contents Kidney Int
  (Kidney International 106, 2 (2024))
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  Subscription Information Kidney Int
  (Kidney International 106, 2 (2024))
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  Editorial Board Kidney Int
  (Kidney International 106, 2 (2024))
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  DNA-binding protein-A: a multitool in tubular epithelial cells - Patrick Droste, Peter Boor, Roman D. Bülow Kidney Int
  Acute kidney injury is still associated with high morbidity and mortality. Reichardt et al. investigated DNA-binding protein-A (Ybx3) in acute kidney injury induced by ischemia-reperfusion injury and found that mice lacking Ybx3 have altered mitochondrial function and increased antioxidant (…) (Kidney International 106, 2 (2024))
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  journal club Kidney Int
  Marfella et al. (Microplastics and nanoplastics in atheromas and cardiovascular events. N Engl J Med. 2024;390:900–910. https://doi.org/10.1056/NEJMoa2309822) (Kidney International 106, 2 (2024))
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  Results of the EPISODE trial plead for reasonable practice-based serum phosphate lowering in patients on dialysis - Takayuki Hamano, Masafumi Fukagawa Kidney Int
  Phosphate toxicity includes induction of parathyroid hyperplasia, especially in the setting of kidney failure, resultant secondary hyperparathyroidism, and bone fragility. Moreover, recent studies have uncovered the toxic effects of phosphate excess on the cardiovascular system and the aging (…) (Kidney International 106, 2 (2024))
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  in this issue Kidney Int
  Acute kidney injury (AKI) in hospitalized patients seems to be a common occurrence when seen through the lens of a consulting nephrologist. But considering the number of hospitalizations that occur each year and the many patients who undergo treatments and procedures that may affect the kidney, (…) (Kidney International 106, 2 (2024))
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  Normalizing serum phosphate based on association, not causation? Lessons in dialysis should have taught us not to fix what we can’t prove is broken - Nigel D. Toussaint, Sunil V. Badve Kidney Int
  Phosphate homeostasis in humans is coordinated by complex interactions between the intestine, parathyroid glands, kidneys, and bone. In people with advanced chronic kidney disease (CKD), dysregulation of these systems results in hyperphosphatemia, which may possibly have serious clinical (…) (Kidney International 106, 2 (2024))
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  Any reduction in maternal kidney mass associated with adverse pregnancy outcomes: more evidence is needed - Shiyuan Wei, Qi Gao, Yanqin Li, Licong Su Kidney Int
  We read the article with interest written by Piccoli et al.1 The authors conducted a prospective study involving 421 cases with chronic kidney disease stage 1, without hypertension and with proteinuria < 0.5 g/d, and 842 controls, and found that a small reduction in kidney mass is associated (…) (Kidney International 106, 2 (2024))
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  The authors reply - Giorgina B. Piccoli, Massimo Torreggiani, Rossella Attini, Gianfranca Cabiddu Kidney Int
  We are grateful to Wei et al.1 for giving us an opportunity to emphasize the need for more attention to chronic kidney disease (CKD) in pregnancy. (Kidney International 106, 2 (2024))
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  Reducing serum phosphate level: how low should we go? - Tilman B. Drüeke Kidney Int
  Phosphate is indispensable for all forms of animal and vegetable life. It is a vital component of DNA, RNA, and proteins and is responsible for numerous enzymatic reactions within the cells. In humans, ?85% of phosphate is located in bone and teeth. The issue of the present controversy is that (…) (Kidney International 106, 2 (2024))
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  In memoriam: Eduardo Slatopolsky, MD, 1934–2024 - Ezequiel Bellorin-Font, Marcos Rothstein, Kevin J. Martin Kidney Int
  Eduardo Slatopolsky, MD, The Joseph Friedman Professor Emeritus of Medicine at Washington University, a major figure in nephrology, passed away on April 24, 2024. He was 89 years old and dedicated almost 60 years to the study of kidney pathophysiology and mineral metabolism in chronic kidney (…) (Kidney International 106, 2 (2024))
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  Unusual cause of retroperitoneal leak in a patient undergoing peritoneal dialysis - Nicolas A.D. Bergeron, Alexandre Candellier, Mathieu Rousseau-Gagnon, Fabrice Mac-Way Kidney Int
  A 63-year-old woman who had been on continuous cycling peritoneal dialysis (PD) for 24 months for end-stage kidney disease due to a homozygous required for meiotic nuclear division 1 homolog (RMND1) mutation was evaluated for a 3-kg weight gain and reduced dialysate effluent in less than a week. (…) (Kidney International 106, 2 (2024))
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  Large lysosomes in Chédiak-Higashi syndrome - Wenyan Zhou, Jerome C. Lane, Anthony Chang Kidney Int
  A 17-year-old female patient with a history of Chédiak-Higashi syndrome and stem cell transplantation 15 years prior was referred for intermittent glucosuria and proteinuria (3+) on urinalysis. Her history also included drug-induced lupus without nephritis 2 years prior. Laboratory results (…) (Kidney International 106, 2 (2024))
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  Uremic stomatitis - Jason M. Kidd, Kennerly Patrick, Sriram Sriperumbuduri Kidney Int
  A 44-year-old man with a history of chronic kidney disease stage V due to biopsy-proven focal segmental glomerulosclerosis developed a white coating over his tongue associated with a painful, burning sensation. He contacted his nephrologist and was treated with nystatin and fluconazole (…) (Kidney International 106, 2 (2024))
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  The Case | Asymmetric kidney cysts in a patient with negative family history - Othmane Mohib, Suzanne Vanhauwaert, Lisanne De Boeck, Kathleen B.M. Claes, Peter Janssens Kidney Int
  A 43-year-old Caucasian man presented at the outpatient nephrology clinic with suspected autosomal dominant polycystic kidney disease (ADPKD) after echography conducted for abdominal pain revealed kidney cysts. His pertinent medical history includes well-controlled type 1 HIV infection treated (…) (Kidney International 106, 2 (2024))
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  Acute kidney injury genetic risks: taking it 1 SNP at a time - Jonathan Himmelfarb, Ian B. Stanaway, Pavan K. Bhatraju Kidney Int
  This commentary addresses some of the strengths, shortcomings, and challenges of the genome-wide association study of acute kidney injury (AKI) report in this issue. This AKI genome-wide association study is well executed and provides significant progress in finding 2 genome-wide significant (…) (Kidney International 106, 2 (2024))
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  Lactate: a missing link between metabolism and inflammation in CKD progression? - Nobuaki Nishima, Shinji Tanaka Kidney Int
  Persistent enhancement of glycolysis in kidney tubular epithelial cells has been linked to the progression of chronic kidney disease, although the underlying mechanisms are largely unknown. In this issue of Kidney International, Wang et al. report that the glycolytic enzyme (…) (Kidney International 106, 2 (2024))

27 juillet

Kidney Int http://www.kidney-international.org/

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  Pseudogene GSTM3P1 derived long non-coding RNA promotes ischemic acute kidney injury by target directed microRNA degradation of kidney-protective mir-668. - Qingqing Wei, Jing Huang, Man Jiang Livingston, Shixuan Wang, Guie Dong, Hongyan Xu, Jiliang Zhou, Zheng Dong Kidney Int
  Long non-coding RNAs (lncRNAs) are a group of epigenetic regulators that have been implicated in kidney diseases including acute kidney injury (AKI). However, very little is known about the specific lncRNAs involved in AKI and the mechanisms underlying their pathologic roles. Here, we report a (…) (Kidney International (2024))