25 October

Eur Heart J https://academic.oup.com/site_5375/

• 02:00
  Cardiovascular Genetics in the European Heart Journal - Tofield A. Eur Heart J
  The team of Deputy and Associate Editors Heribert Schunkert, Sharlene Day and Peter Schwartz

1 October

Lancet Diab Endocrinol https://www.thelancet.com/journals/landia/home

• 00:00
  [Corrections] Correction to Lancet Diabetes Endocrinol 2021; 9: 491–501 Lancet Diab Endocrinol
  Subbiah V, Hu MI, Wirth LJ et al. Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study. Lancet Diabetes Endocrinol 2021; 9: 491–501—In this Article, the first sentence of the Introduction should read (...) (The Lancet Diabetes & Endocrinology 9, 10 (2021))

J Hypertens http://journals.lww.com/jhypertension/

• 07:00
  The cardio-ankle vascular index as a predictor of adverse pregnancy outcomes - Rueangjaroen, Patcharee; Luewan, Suchaya; Phrommintikul, Arintaya; Leemasawat, Krit; Tongsong, Theera J Hypertens
  Objective: To assess the association between maternal hemodynamic parameters; cardio-ankle vascular index (CAVI), representing arterial stiffness; mean arterial pressure (MAP), uterine artery pulsatility index (Ut-PI), and adverse pregnancy outcomes including preeclampsia (PE), fetal growth (...) -- ORIGINAL PAPERS: BP variability and monitoring
• 07:00
  Impact of stroke work on the ability of left ventricular mass to account for pressure effects on function in a community with prevalent systemic flow-dependent hypertension - Bello, Hamza; Woodiwiss, Angela J.; Naran, Ravi; Peterson, Vernice R.; Libhaber, Carlos D.; Mmopi, Keneilwe N.; Mthembu, Nonhlanhla; Masiu, Mohlabani; Da Silva Fernandes, Daniel; Bamaiyi, Adamu J.; Peters, Ferande; Sareli, Pinhas; Norton, Gavin R. J Hypertens
  Aims: To determine whether the confounding influence of stroke work on left ventricular mass (LVM) limits the ability of LVM to detect hypertensive LV dysfunction in systemic flow-dependent hypertension. Methods: In a community with prevalent systemic flow-dependent hypertension (n = 709), (...) -- ORIGINAL PAPERS: Cardiac function
• 07:00
  Myocardial strain in hypertension: a meta-analysis of two-dimensional speckle tracking echocardiographic studies - Tadic, Marijana; Sala, Carla; Carugo, Stefano; Mancia, Giuseppe; Grassi, Guido; Cuspidi, Cesare J Hypertens
  Aim: Available evidence on systolic dysfunction in systemic hypertension, as assessed by left ventricular (LV) mechanics, is still based on single studies. Thus, we performed a systematic meta-analysis of two-dimensional speckle-tracking studies in order to provide an updated comprehensive (...) -- ORIGINAL PAPERS: Cardiac function
• 07:00
  Association of central arterial stiffness with hippocampal blood flow and N-acetyl aspartate concentration in hypertensive adult Dahl salt sensitive rats - Ajamu, Samuel O.; Fenner, Rachel C.; Grigorova, Yulia N.; Cezayirli, Defne; Morrell, Christopher H.; Lakatta, Edward G.; Bouhrara, Mustapha; Spencer, Richard G.; Fedorova, Olga V.; Fishbein, Kenneth W. J Hypertens
  Background: Central arterial stiffness (CAS) is associated with elevated arterial blood pressure (BP) and is likely associated with stiffening of cerebral artery walls, with attendant cerebral hypoperfusion, neuronal density loss and cognitive decline. Dahl salt-sensitive (Dahl-S) rats exhibit (...) -- ORIGINAL PAPERS: Basic science
• 07:00
  Cancer, hypertension and risk for cardiovascular disease - Kawada, Tomoyuki J Hypertens
  No abstract available -- CORRESPONDENCE
• 07:00
  Reply - Liu, Fei; Hidru, Tesfaldet H.; Yang, Xiaolei; Xia, Yunlong J Hypertens
  No abstract available -- CORRESPONDENCE
• 07:00
  The Journal Executive Team - Heagerty, Anthony M. J Hypertens
  No abstract available -- EDITOR\'S CORNER
• 07:00
  Adaptation of left ventricular diastolic function to pregnancy: a systematic review and meta-analysis - de Haas, Sander; Spaanderman, Marc E.A.; van Kuijk, Sander M.J.; van Drongelen, Joris; Mohseni, Zenab; Jorissen, Laura; Ghossein-Doha, Chahinda J Hypertens
  Objective: To meta-analytically determine the adaptation of left ventricular diastolic function (LVDF)-indices to singleton normotensive pregnancies. Methods: Literature was retrieved from PubMed and Embase. We included studies that reported a nonpregnant reference measurement and LVDF indices (...) -- REVIEWS AND META-ANALYSES
• 07:00
  Blood pressure in adults with cerebral palsy: a systematic review and meta-analysis of individual participant data - Noten, Suzie; van den Berg-Emons, Rita J.G.; Thorpe, Deborah E.; Heyn, Patricia C.; Marciniak, Christina M.; McPhee, Patrick G.; Lamberts, Robert P.; Langerak, Nelleke G.; Verschuren, Olaf; Salokivi, Tommi; Morrison, Katherine M.; Peterson, Mark D.; Limsakul, Chonnanid; Stam, Henk J.; Papageorgiou, Grigorios; Versmissen, Jorie; Van Der Slot, Wilma M.A. J Hypertens
  Objectives: This systematic review and meta-analysis was designed to determine the overall mean blood pressure and prevalence of hypertension among a representative sample of adults living with cerebral palsy by combining individual participant data. Additional objectives included estimating (...) -- REVIEWS AND META-ANALYSES
• 07:00
  Maternal myocardial dysfunction after hemolysis, elevated liver enzymes, and low platelets syndrome: a speckle-tracking study - Sciatti, Edoardo; Mohseni, Zenab; Orabona, Rossana; Mulder, Eva G.; Prefumo, Federico; Lorusso, Roberto; Frusca, Tiziana; Ghossein-Doha, Chahinda; Spaanderman, Marc E.A. J Hypertens
  Objectives: Pregnancy complicated by pre-eclampsia (PE) and hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is associated with an increased risk of cardiovascular (CV) diseases later in life. Subclinical cardiac alterations precede eminent CV diseases. Speckle-tracking (...) -- ORIGINAL PAPERS: Diagnostics
• 07:00
  Time trends in the relation between blood pressure and dementia in 85-year-olds - Ribbe, Mats; Kern, Silke; Wetterberg, Hanna; Rydén, Lina; Zettergren, Anna; Guo, Xinxin; Skoog, Ingmar J Hypertens
  Objectives: Blood pressure has decreased in the general population. We aimed to examine whether this is true also among the very old, and among persons with and without dementia. Further, we aimed to investigate how common undetected and untreated hypertension is in the very old, both among (...) -- ORIGINAL PAPERS: Diagnostics
• 07:00
  An exploratory analysis of comparative plasma metabolomic and lipidomic profiling in salt-sensitive and salt-resistant individuals from The Dietary Approaches to Stop Hypertension Sodium Trial - Chaudhary, Parul; Velkoska, Elena; Wainford, Richard D. J Hypertens
  Objective: This study conducted exploratory metabolomic and lipidomic profiling of plasma samples from the DASH (Dietary Approaches to Stop Hypertension) Sodium Trial to identify unique plasma biomarkers to identify salt-sensitive versus salt-resistant participants. Methods: Utilizing plasma (...) -- ORIGINAL PAPERS: Diagnostics
• 07:00
  Relation between elevated first SBP from baseline (delta SBP) and postoperative outcome - Zhou, Yan; Liu, Lin; Fan, Fangfang; Hong-Yun, Yang J Hypertens
  Background: Hypertension is associated with increased postoperative risk. However, no consensus was accepted whether elevated blood pressure in the operating room with normal blood pressure at rest related to additional cardiovascular risk. Methods: This was a single-center retrospective cohort (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Characteristics of people with severe hypertension in France and determinants of medication persistence after 6 years - Tuppin, Philippe; Denis, Pierre; Gastaldi, Christelle; Olié, Valérie; Blacher, Jacques J Hypertens
  Background: Low medication persistence is reported in patients with severe hypertension but few data are available according to drug classes. Method: Adults without cardiovascular disease who started treatment, in a semester between 2010 and 2012, with two concurrent dispensings of at least (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Isolated diastolic vs. systolic hypertension phenotypes and outcomes: prospective cohort of newly diagnosed individuals with hypertension - Thomopoulos, Costas; Andrikou, Ioannis; Konstantinidis, Dimitris; Iliakis, Panagiotis; Kalos, Theodoros; Polyzos, Dimitrios; Drogkaris, Sotirios; Siafi, Eirini; Tousoulis, Dimitrios; Stergiou, George S.; Tsioufis, Costas J Hypertens
  Aims: To evaluate whether different hypertension phenotypes, namely, isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH) and systolic/diastolic hypertension (SDH) have a differential outcome effect by clinic and ambulatory blood pressure (BP) measurements. Methods: We (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Relationships between cardiovascular risk factors and white-coat hypertension diagnosed by home blood pressure recordings in a middle-aged population - Johansson, Martina A.K.; Östgren, Carl Johan; Engvall, Jan; Swahn, Eva; Wijkman, Magnus; Nystrom, Fredrik H. J Hypertens
  Objective: To study risk in white-coat hypertension (WCH) by measurement of coronary artery calcium score (CACS), carotid--femoral pulse-wave velocity (PWV) and carotid plaques. Methods: Cross-sectional population-based cohort with randomized selection of participants from Linköping, Sweden. An (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Trends in cause-related comorbidities in hospitalized patients with secondary hypertension in China from 2013 to 2016: a retrospective analysis of hospital quality monitoring system data - Zhang, Long; Li, Jianping; Li, Nanfang; Sun, Ningling; Xie, Liangdi; Han, Qinghua; Li, Yong; Lu, Xin Zheng; Sun, Pengfei; Li, Yuxi; Shi, Ying; Wang, Haibo; Zhang, Yan; Chen, Hu; Huo, Yong J Hypertens
  Background: Secondary hypertension has emerged as a major public health problem in China. Early diagnosis and treatment can significantly improve the clinical outcomes. However, data on the current cause composition in China are seldom reported. Objective: To describe the trends in (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Novel insights into stroke risk beyond resting and maximal bicycle exercise systolic blood pressure - Mariampillai, Julian E.; Prestgaard, Erik E.; Kjeldsen, Sverre E.; Liestøl, Knut; Grundvold, Irene; Bodegård, Johan; Gjesdal, Knut; Erikssen, Jan E.; Skretteberg, Per T. J Hypertens
  Objective: Previous research has shown an association between moderate workload exercise blood pressure (BP) and coronary disease, whereas maximal exercise BP is associated with stroke. We aimed to investigate the association between the increase in BP during maximal exercise and the long-term (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Association of self-measured home, ambulatory, and strictly measured office blood pressure and their variability with intracranial arterial stenosis - Hisamatsu, Takashi; Ohkubo, Takayoshi; Hozawa, Atsushi; Fujiyoshi, Akira; Torii, Sayuki; Segawa, Hiroyoshi; Kondo, Keiko; Kadota, Aya; Takashima, Naoyuki; Shitara, Satoshi; Arima, Hisatomi; Nakagawa, Yoshihisa; Watanabe, Yoshiyuki; Shiino, Akihiko; Nozaki, Kazuhiko; Ueshima, Hirotsugu; Miura, Katsuyuki; for the SESSA Research Group J Hypertens
  Objective: Hypertension and intracranial artery stenosis (ICAS) are closely related; however, few studies have compared the strength of the relationship between strictly measured office and out-of-office blood pressure (BP) measurements. The relationship of day-by-day or short-term variability (...) -- ORIGINAL PAPERS: BP and other risk factor epidemiology
• 07:00
  Abnormalities in emotional and motor reactions among young prehypertensive individuals: employing continuous blood pressure analysis - Wiener, Avigail; Goldstein, Pavel; Doenyas, Keren; Okon-Singer, Hadas J Hypertens
  Background: Essential hypertension is an important risk factor for cerebrovascular diseases and a major cause of premature death in industrialized societies. A predisposing factor for essential hypertension is prehypertension: blood pressure (BP) values at rest that are at the higher end of the (...) -- ORIGINAL PAPERS: Prehypertension
• 07:00
  Effects of hormone replacement therapy on endothelial function, arterial stiffness and myocardial deformation in women with Turner syndrome - Peppa, Melpomeni; Pavlidis, George; Mavroeidi, Ioanna; Katogiannis, Konstantinos; Varoudi, Maria; Thymis, John; Kostelli, Gavriella; Vlastos, Dimitrios; Plotas, Panagiotis; Bamias, Aristotelis; Parissis, John; Ikonomidis, Ignatios J Hypertens
  Objectives: Turner syndrome (TS) is associated with increased cardiovascular risk. We investigated whether hormone replacement therapy (HRT) affects endothelial function, arterial stiffness and myocardial deformation in women with TS. Methods: Twenty-five women with TS were studied in the (...) -- ORIGINAL PAPERS: Prehypertension
• 07:00
  Synergistic harmful interaction between sustained physical inactivity and hypertension/diabetes mellitus on the risk of all-cause mortality: a retrospective observational cohort study - Lee, Chang-Hoon; Han, Kyung-Do; Yoo, Juhwan; Kwak, Min-Sun J Hypertens
  Objective: Hypertension, diabetes mellitus and physical inactivity can cause cardiovascular complications or premature death. However, it has not been clarified whether those major comorbidities and physical activity interact in affecting health outcomes. The aim of this study is to evaluate (...) -- ORIGINAL PAPERS: Prehypertension
• 07:00
  The association of blood pressure variability with adverse outcomes in a primary care chronic kidney disease cohort - Pallikadavath, Susil; Chambers, Lucy; Shepherd, David; Sukhnani, Mahak; Medcalf, James F.; Gray, Laura J.; Brunskill, Nigel J.; Major, Rupert W. J Hypertens
  Background: Hypertension is common in individuals with chronic kidney disease and both conditions are associated with adverse outcomes including cardiovascular morbidity. Therefore, it is clinically important to identify methods of risk prediction in individuals with chronic kidney disease. (...) -- ORIGINAL PAPERS: BP variability and monitoring
• 07:00
  Feasibility of 24-h blood pressure telemonitoring in community pharmacies: the TEMPLAR project - Omboni, Stefano; Ballatore, Tommaso; Rizzi, Franco; Tomassini, Fernanda; Campolo, Luca; Panzeri, Edoardo J Hypertens
  Objectives: Low-quality ambulatory blood pressure monitoring (ABPM) due to recurring artifacts may limit its clinical value. We evaluated the features and impact on BP control and patient management of ABPMs performed in Italian community pharmacies, according to their quality. Methods: (...) -- ORIGINAL PAPERS: BP variability and monitoring

Curr Opin Endocrinol http://journals.lww.com/co-endocrinology

• 07:00
  Editorial introductions Curr Opin Endocrinol
  No abstract available -- EDITORIAL INTRODUCTIONS
• 07:00
  Editorial: Carbohydrate restriction: from the ‘bedside’ to the ‘bench’ - Westman, Eric C. Curr Opin Endocrinol
  No abstract available -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Carbohydrate-restricted diets and Type 1 diabetes mellitus: research considerations - Dikeman, David T.; Westman, Eric C. Curr Opin Endocrinol
  Purpose of review Type 1 diabetes mellitus (T1DM) is managed via careful control of blood glucose, exogenous insulin, diet, exercise, and other physiologic factors. Interestingly, the dietary recommendations for T1DM have had very little systematic research. Many clinical observations, as well (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  International patient group harnesses social media to help inform rare disease research: use of a low carbohydrate ketogenic diet in McArdle disease - Reason, Stacey L.; Løkken, Nicoline; Voermans, Nicol Curr Opin Endocrinol
  Purpose of review To highlight the benefits of a partnership between patient advocacy organizations (PAO) and clinical researchers in order to clinically study the prior anecdotal patient experience of utilizing a low-carbohydrate ketogenic diet (LCKD) to manage McArdle disease. Recent findings (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  A case study of overfeeding 3 different diets - Feltham, Sam; Westman, Eric C. Curr Opin Endocrinol
  Purpose of review Quality or quantity of food has been at the heart of the diet debate for decades and will seemingly continue for many to come unless tightly controlled studies are conducted. To our knowledge, there has never been an overfeeding study comparing the effects of multiple diets. (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Nutritional ketosis is well-tolerated, even in type 1 diabetes: the ZeroFive100 Project; a proof-of-concept study - Lake, Ian Curr Opin Endocrinol
  Purpose of review The objective of this study was to test the feasibility of exercising over a 5-day period while fasting, in those with and without type 1 diabetes mellitus (T1DM). Eight individuals, ages 29--62 years, two with T1DM, walked/ran around 20 miles per day for five consecutive days (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Effect of low carbohydrate diets on insulin resistance and the metabolic syndrome - Foley, Peter J. Curr Opin Endocrinol
  Purpose of review This review outlines recent research in the application of low carbohydrate diets (LCD) for insulin resistance (IR) and metabolic syndrome (MetS). Recent findings Studies included in this review explore how a LCD can be used in the management of patients with IR and MetS. LCDs (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Renal function in patients following a low carbohydrate diet for type 2 diabetes: a review of the literature and analysis of routine clinical data from a primary care service over 7 years - Unwin, David; Unwin, Jen; Crocombe, Dominic; Delon, Christine; Guess, Nicola; Wong, Christopher Curr Opin Endocrinol
  Purpose of review People with T2 Diabetes (T2D) who follow a low carbohydrate diet (LCD) may increase their dietary protein intake. Dietary protein can modulate renal function so there is debate about its role in renal disease. There is concern that higher protein intakes may promote renal (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Retrospective cohort study of changes in estimated glomerular filtration rate for patients prescribed a low carb diet - Mitchell, Nia S.; Batch, Bryan C.; Tyson, Crystal C. Curr Opin Endocrinol
  Purpose of review Obesity and diabetes contribute to chronic kidney disease (CKD) and accelerate the loss of kidney function. Low carbohydrate diets (LCDs) are associated with weight loss and improved diabetes control. Compared to the typical Western diet, LCDs contain more protein, so (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Ketogenic diet as an advanced option for the management of pediatric obesity - Favret, Jenny; Wood, Charles T.; Maradiaga Panayotti, Gabriela M. Curr Opin Endocrinol
  Purpose of review The Duke Healthy Lifestyles Program (HL), established in 2006, has treated over 15,000 pediatric patients with obesity. A subset of patients with obesity do not respond to dietary and lifestyle changes. Development of the Staged Transitional Eating Plan (STEP) in 2012 provided (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Brief intervention of low carbohydrate dietary advice: clinic results and a review of the literature - Oliver, David; Andrews, Kim Curr Opin Endocrinol
  Purpose of review The purpose of the review is to assess the efficacy of a brief intervention of low carbohydrate dietary advice for weight loss in patients with a raised body mass index (BMI) (>25 kg/m2) during routine patient appointments in primary care. Recent findings Brief interventions (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  The therapeutic properties of ketogenic diets, slow-wave sleep, and circadian synchrony - O’Hearn, L. Amber Curr Opin Endocrinol
  Purpose of review To summarize emerging connections between sleep, ketogenic diets, and health. Recent findings Mechanisms involved in the therapeutic benefits of ketogenic diets continue to be elucidated. Concurrently, the importance of sleep quality and circadian rhythms in their effects on (...) -- OBESITY AND NUTRITION: Edited by Eric C. Westman
• 07:00
  Editorial: Current opinions in endocrinology and diabetes - Leung, Angela M. Curr Opin Endocrinol
  No abstract available -- THYROID: Edited by Angela M. Leung
• 07:00
  Long-term antithyroid drug therapy - Cooper, David S. Curr Opin Endocrinol
  Purpose of review Over the last 1–2 decades, patients and physicians have preferred antithyroid drug therapy as the initial treatment of Graves’ disease, rather than radioactive iodine or surgery. More recently, the concept of long-term antithyroid drug therapy (LTADT; >24 months of treatment) (...) -- THYROID: Edited by Angela M. Leung
• 07:00
  Survival benefit of endocrine dysfunction following immune checkpoint inhibitors for nonthyroidal cancers - Kotwal, Anupam; Ryder, Mabel Curr Opin Endocrinol
  Purpose of review Our goal is to review pertinent data evaluating the association between immune checkpoint inhibitor (ICI)-induced endocrine dysfunction and survival in cancer patients as well as to understand the potential molecular links between these. Recent findings ICIs have (...) -- THYROID: Edited by Angela M. Leung
• 07:00
  Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and thyroid disease. An update - Brix, Thomas H.; Hegedüs, Laszlo Curr Opin Endocrinol
  Purpose of review Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with excess morbidity and mortality in patients with hypertension and diabetes but little is known about thyroid diseases. Thus, our goal was to review the literature with respect to: (i) Are (...) -- THYROID: Edited by Angela M. Leung
• 07:00
  Patient perception of receiving a thyroid cancer diagnosis - Jensen, Catherine B.; Pitt, Susan C. Curr Opin Endocrinol
  Purpose of review This review describes the current state of the literature on patients’ perceptions of receiving a diagnosis of thyroid cancer. The evaluation progresses from people's understanding about thyroid cancer in general to the lived experiences of those receiving an initial diagnosis (...) -- THYROID: Edited by Angela M. Leung
• 07:00
  Medullary thyroid carcinoma - Jaber, Tania; Dadu, Ramona; Hu, Mimi I. Curr Opin Endocrinol
  Purpose of review To summarize recent developments in the diagnosis and management of patients with medullary thyroid cancer (MTC), with a focus on pathogenesis, systemic therapy, and future directions. Recent findings The addition of mutational analysis to cytological assessment of thyroid (...) -- THYROID: Edited by Angela M. Leung
• 07:00
  Appropriate selection of candidates for outpatient thyroidectomy - Romero Arenas, Minerva Angélica Curr Opin Endocrinol
  Purpose of review Although traditionally an inpatient procedure, outpatient thyroidectomy has gained traction as a viable and well tolerated alternative for selected patients, with an added benefit of cost savings. Recent findings Research on outpatient thyroidectomy has focused on establishing (...) -- THYROID: Edited by Angela M. Leung

Diabetologia http://link.springer.com/

• 00:00
  Correction to: Youth-onset type 2 diabetes: translating epidemiology into clinical trials Diabetologia
  A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05518-z
• 00:00
  Correction to: Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control Diabetologia
  Abstract A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05544-x
• 00:00
  On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes: Reply to Johnson JD [letter] Diabetologia
• 00:00
  Up front Diabetologia
• 00:00
  On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes Diabetologia
  Abstract Hundreds of millions of people are affected by hyperinsulinaemia, insulin resistance, obesity and the dysglycaemia that mark a common progression from metabolic health to type 2 diabetes. Although the relative contribution of these features and the order in which they appear may (...)
• 00:00
  Sleep quality and glycaemic variability in a real-life setting in adults with type 1 diabetes Diabetologia
  Abstract Aims/hypothesis Suboptimal subjective sleep quality is very common in adults with type 1 diabetes. Reducing glycaemic variability is a key objective in this population. To date, no prior studies have examined the associations between objectively measured sleep quality and overnight (...)
• 00:00
  Use of incretin-based drugs and risk of cholangiocarcinoma: Scandinavian cohort study Diabetologia
  Abstract Aims/hypothesis Concerns have been raised regarding a potential association of use of the incretin-based drugs dipeptidyl peptidase 4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1)-receptor agonists with risk of cholangiocarcinoma. We examined this association in nationwide (...)
• 00:00
  How does exposure to overnutrition in utero lead to childhood adiposity? Testing the insulin hypersecretion hypothesis in the EPOCH cohort Diabetologia
  Abstract Aims/hypothesis Our aim was to explore metabolic pathways linking overnutrition in utero to development of adiposity in normal-weight children. Methods We included 312 normal-weight youth exposed or unexposed to overnutrition in utero (maternal BMI ?25 kg/m2 or gestational diabetes). (...)
• 00:00
  Development of a life expectancy table for individuals with type 1 diabetes Diabetologia
  Abstract Aims/hypothesis Tables reporting life expectancies by common risk factors are available for individuals with type 2 diabetes; however, there is currently no published equivalent for individuals with type 1 diabetes. We aimed to develop a life expectancy table using a recently (...)
• 00:00
  Association of maternal vitamin B12 and folate levels in early pregnancy with gestational diabetes: a prospective UK cohort study (PRiDE study) Diabetologia
  Abstract Aims/hypothesis The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide in all ethnic groups. Low vitamin B12 and low/high folate levels may contribute to GDM risk, but there is conflicting evidence. Our aim is to assess the relationships of early pregnancy (...)
• 00:00
  Retinal arteriolar tortuosity and fractal dimension are associated with long-term cardiovascular outcomes in people with type 2 diabetes Diabetologia
  Abstract Aims/hypothesis Our aim was to determine whether quantitative retinal traits in people with type 2 diabetes are independently associated with incident major cardiovascular events including CHD and stroke. Methods A total of 1066 men and women with type 2 diabetes, aged 65–74 years, (...)
• 00:00
  DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life Diabetologia
  Abstract Aims/hypothesis Among white European children developing type 1 diabetes, the otherwise common HLA haplotype DR15-DQ6 is rare, and highly protective. Adult-onset type 1 diabetes is now known to represent more overall cases than childhood onset, but it is not known whether DR15-DQ6 is (...)
• 00:00
  Altered cellular localisation and expression, together with unconventional protein trafficking, of prion protein, PrPC, in type 1 diabetes Diabetologia
  Abstract Aims/hypothesis Normal cellular prion protein (PrPC) is a conserved mammalian glycoprotein found on the outer plasma membrane leaflet through a glycophosphatidylinositol anchor. Although PrPC is expressed by a wide range of tissues throughout the body, the complete repertoire of its (...)
• 00:00
  Correction to: Youth-onset type 2 diabetes: translating epidemiology into clinical trials Diabetologia
  A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05518-z
• 00:00
  Correction to: Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control Diabetologia
  Abstract A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05544-x
• 00:00
  On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes: Reply to Johnson JD [letter] Diabetologia
• 00:00
  Up front Diabetologia
• 00:00
  On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes Diabetologia
  Abstract Hundreds of millions of people are affected by hyperinsulinaemia, insulin resistance, obesity and the dysglycaemia that mark a common progression from metabolic health to type 2 diabetes. Although the relative contribution of these features and the order in which they appear may (...)
• 00:00
  Sleep quality and glycaemic variability in a real-life setting in adults with type 1 diabetes Diabetologia
  Abstract Aims/hypothesis Suboptimal subjective sleep quality is very common in adults with type 1 diabetes. Reducing glycaemic variability is a key objective in this population. To date, no prior studies have examined the associations between objectively measured sleep quality and overnight (...)
• 00:00
  Use of incretin-based drugs and risk of cholangiocarcinoma: Scandinavian cohort study Diabetologia
  Abstract Aims/hypothesis Concerns have been raised regarding a potential association of use of the incretin-based drugs dipeptidyl peptidase 4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1)-receptor agonists with risk of cholangiocarcinoma. We examined this association in nationwide (...)
• 00:00
  How does exposure to overnutrition in utero lead to childhood adiposity? Testing the insulin hypersecretion hypothesis in the EPOCH cohort Diabetologia
  Abstract Aims/hypothesis Our aim was to explore metabolic pathways linking overnutrition in utero to development of adiposity in normal-weight children. Methods We included 312 normal-weight youth exposed or unexposed to overnutrition in utero (maternal BMI ?25 kg/m2 or gestational diabetes). (...)
• 00:00
  Development of a life expectancy table for individuals with type 1 diabetes Diabetologia
  Abstract Aims/hypothesis Tables reporting life expectancies by common risk factors are available for individuals with type 2 diabetes; however, there is currently no published equivalent for individuals with type 1 diabetes. We aimed to develop a life expectancy table using a recently (...)
• 00:00
  Association of maternal vitamin B12 and folate levels in early pregnancy with gestational diabetes: a prospective UK cohort study (PRiDE study) Diabetologia
  Abstract Aims/hypothesis The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide in all ethnic groups. Low vitamin B12 and low/high folate levels may contribute to GDM risk, but there is conflicting evidence. Our aim is to assess the relationships of early pregnancy (...)
• 00:00
  Retinal arteriolar tortuosity and fractal dimension are associated with long-term cardiovascular outcomes in people with type 2 diabetes Diabetologia
  Abstract Aims/hypothesis Our aim was to determine whether quantitative retinal traits in people with type 2 diabetes are independently associated with incident major cardiovascular events including CHD and stroke. Methods A total of 1066 men and women with type 2 diabetes, aged 65–74 years, (...)
• 00:00
  DR15-DQ6 remains dominantly protective against type 1 diabetes throughout the first five decades of life Diabetologia
  Abstract Aims/hypothesis Among white European children developing type 1 diabetes, the otherwise common HLA haplotype DR15-DQ6 is rare, and highly protective. Adult-onset type 1 diabetes is now known to represent more overall cases than childhood onset, but it is not known whether DR15-DQ6 is (...)
• 00:00
  Altered cellular localisation and expression, together with unconventional protein trafficking, of prion protein, PrPC, in type 1 diabetes Diabetologia
  Abstract Aims/hypothesis Normal cellular prion protein (PrPC) is a conserved mammalian glycoprotein found on the outer plasma membrane leaflet through a glycophosphatidylinositol anchor. Although PrPC is expressed by a wide range of tissues throughout the body, the complete repertoire of its (...)

16 September

Diabetes https://diabetes.diabetesjournals.org

• 16:58
  A Hundred Years of Insulin Innovation: When Science Meets Technology - Kjeldsen, T.; Kurtzhals, P. Diabetes
• 16:58
  From Pancreatic beta-Cell Gene Networks to Novel Therapies for Type 1 Diabetes - Eizirik, D. L.; Szymczak, F.; Alvelos, M. I.; Martin, F. Diabetes
  Completion of the Human Genome Project enabled a novel systems- and network-level understanding of biology, but this remains to be applied for understanding the pathogenesis of type 1 diabetes (T1D). We propose that defining the key gene regulatory networks that drive β-cell dysfunction (...)
• 16:58
  Surplus Ceramides: An Added Twist in the Tale of TREM2 and Insulin Resistance - Webster, K. L.; Becker, L. Diabetes
• 16:58
  The Role of GIP Receptor in the CNS for the Pathogenesis of Obesity - Fukuda, M. Diabetes
  Glucose-dependent insulinotropic polypeptide (GIP) (also known as gastric inhibitory polypeptide) is a hormone produced in the upper gut and secreted to the circulation in response to the ingestion of foods, especially fatty foods. Growing evidence supports the physiological and pharmacological (...)
• 16:58
  GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Basedz Therapies in Treating Metabolic Disorders - Samms, R. J.; Sloop, K. W.; Gribble, F. M.; Reimann, F.; Adriaenssens, A. E. Diabetes
  During the past decade, pharmaceutical engineering of unimolecular agents has revealed the therapeutic potential of glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism. From this work, one of the most intriguing findings is that engagement of GIPR enhances the weight loss (...)
• 16:58
  Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex - Ludwig, M. Q.; Todorov, P. V.; Egerod, K. L.; Olson, D. P.; Pers, T. H. Diabetes
  The dorsal vagal complex (DVC) in the hindbrain, composed of the area postrema, nucleus of the solitary tract, and dorsal motor nucleus of the vagus, plays a critical role in modulating satiety. The incretins glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) (...)
• 16:58
  The Role of GIP in the Regulation of GLP-1 Satiety and Nausea - Hayes, M. R.; Borner, T.; De Jonghe, B. C. Diabetes
  Gastric inhibitory peptide (GIP) is best known for its role as an incretin hormone in control of blood glucose concentrations. As a classic satiation signal, however, the literature illustrates a mixed picture of GIP involvement with an at best weak anorectic response profile being reported for (...)
• 16:58
  Applying CRISPR Screen in Diabetes Research - Yi, P.; Morrow, N. Diabetes
  The CRISPR/Cas9 genome editing system has been one of the greatest scientific discoveries in the last decade. The highly efficient and precise editing ability of this technology is of great therapeutic value and benefits the basic sciences as an advantageous research tool. In recent years, (...)
• 16:58
  Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2 - Corsa, C. A. S.; Walsh, C. M.; Bagchi, D. P.; Foss Freitas, M. C.; Li, Z.; Hardij, J.; Granger, K.; Mori, H.; Schill, R. L.; Lewis, K. T.; Maung, J. N.; Azaria, R. D.; Rothberg, A. E.; Oral, E. A.; MacDougald, O. A. Diabetes
  Mechanisms by which autosomal recessive mutations in Lmna cause familial partial lipodystrophy type 2 (FPLD2) are poorly understood. To investigate the function of lamin A/C in adipose tissue, we created mice with an adipocyte-specific loss of Lmna (LmnaADKO). Although LmnaADKO mice develop and (...)
• 16:58
  Insulin Directly Regulates the Circadian Clock in Adipose Tissue - Tuvia, N.; Pivovarova-Ramich, O.; Murahovschi, V.; Lu?ck, S.; Grudziecki, A.; Ost, A.-C.; Kruse, M.; Nikiforova, V. J.; Osterhoff, M.; Gottmann, P.; Go?gebakan, O.; Sticht, C.; Gretz, N.; Schupp, M.; Schu?rmann, A.; Rudovich, N.; Pfeiffer, A. F. H.; Kramer, A. Diabetes
  Adipose tissue (AT) is a key metabolic organ which functions are rhythmically regulated by an endogenous circadian clock. Feeding is a "zeitgeber" aligning the clock in AT with the external time, but mechanisms of this regulation remain largely unclear. We tested the hypothesis that (...)
• 16:58
  TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue - Choi, C.; Son, Y.; Kim, J.; Cho, Y. K.; Saha, A.; Kim, M.; Im, H.; Kim, K.; Han, J.; Lee, J. W.; Seong, J. K.; Lee, Y.-H. Diabetes
  Transmembrane 4 L six family member 5 (TM4SF5) functions as a sensor for lysosomal arginine levels and activates the mammalian target of rapamycin complex 1 (mTORC1). While the mTORC1 signaling pathway plays a key role in adipose tissue metabolism, the regulatory function of TM4SF5 in (...)
• 16:58
  HIV-1 Viral Protein R Couples Metabolic Inflexibility With White Adipose Tissue Thermogenesis - Agarwal, N.; Iyer, D.; Saha, P.; Cox, A. R.; Xia, Y.; Utay, N. S.; Somasundaram, A.; Schubert, U.; Lake, J. E.; Hartig, S. M.; Balasubramanyam, A. Diabetes
  Persons living with HIV (PLWH) manifest chronic disorders of brown and white adipose tissues that lead to diabetes and metabolic syndrome. The mechanisms that link viral factors to defective adipose tissue function and abnormal energy balance in PLWH remain incompletely understood. Here, we (...)
• 16:58
  STAT3 Regulates Mitochondrial Gene Expression in Pancreatic beta-Cells and Its Deficiency Induces Glucose Intolerance in Obesity - Schaschkow, A.; Pang, L.; Vandenbempt, V.; Elvira, B.; Litwak, S. A.; Vekeriotaite, B.; Maillard, E.; Vermeersch, M.; Paula, F. M. M.; Pinget, M.; Perez-Morga, D.; Gough, D. J.; Gurzov, E. N. Diabetes
  Most obese and insulin-resistant individuals do not develop diabetes. This is the result of the capacity of β-cells to adapt and produce enough insulin to cover the needs of the organism. The underlying mechanism of β-cell adaptation in obesity, however, remains unclear. Previous (...)
• 16:58
  Beneficial Metabolic Effects of TREM2 in Obesity Are Uncoupled From Its Expression on Macrophages - Sharif, O.; Brunner, J. S.; Korosec, A.; Martins, R.; Jais, A.; Snijder, B.; Vogel, A.; Caldera, M.; Hladik, A.; Lakovits, K.; Saluzzo, S.; Boehm, B.; Gorki, A.-D.; Mesteri, I.; Lindroos-Christensen, J.; Tillmann, K.; Stoiber, D.; Menche, J.; Schabbauer, G.; Bilban, M.; Superti-Furga, G.; Esterbauer, H.; Knapp, S. Diabetes
  Obesity-induced white adipose tissue (WAT) hypertrophy is associated with elevated adipose tissue macrophage (ATM) content. Overexpression of the triggering receptor expressed on myeloid cells 2 (TREM2) reportedly increases adiposity, worsening health. Paradoxically, using insulin resistance, (...)
• 16:58
  The Anna Karenina Model of beta-Cell Maturation in Development and Their Dedifferentiation in Type 1 and Type 2 Diabetes - Nimkulrat, S. D.; Bernstein, M. N.; Ni, Z.; Brown, J.; Kendziorski, C.; Blum, B. Diabetes
  Loss of mature β-cell function and identity, or β-cell dedifferentiation, is seen in both type 1 and type 2 diabetes. Two competing models explain β-cell dedifferentiation in diabetes. In the first model, β-cells dedifferentiate in the reverse order of their developmental (...)
• 16:58
  Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases - Lecuyer, E.; Le Roy, T.; Gestin, A.; Lacombe, A.; Philippe, C.; Ponnaiah, M.; Hure, J.-B.; Fradet, M.; Ichou, F.; Boudebbouze, S.; Huby, T.; Gautier, E.; Rhimi, M.; Maguin, E.; Kapel, N.; Gerard, P.; Venteclef, N.; Garlatti, M.; Chassaing, B.; Lesnik, P. Diabetes
  Excess chronic contact between microbial motifs and intestinal immune cells is known to trigger a low-grade inflammation involved in many pathologies such as obesity and diabetes. The important skewing of intestinal adaptive immunity in the context of diet-induced obesity (DIO) is well (...)
• 16:58
  Deletion of the Feeding-Induced Hepatokine TSK Ameliorates the Melanocortin Obesity Syndrome - Wang, Q.; Zhang, P.; Cakir, I.; Mi, L.; Cone, R. D.; Lin, J. D. Diabetes
  Work in recent decades has established that metabolic hormones released by endocrine cells and diverse other cell types serve to regulate nutrient intake and energy homeostasis. Tsukushi (TSK) is a leucine-rich repeat-containing protein secreted primarily by the liver that exerts an inhibitory (...)
• 16:58
  Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study - Tura, A.; Grespan, E.; Go?bl, C. S.; Koivula, R. W.; Franks, P. W.; Pearson, E. R.; Walker, M.; Forgie, I. M.; Giordano, G. N.; Pavo, I.; Ruetten, H.; Dermitzakis, E. T.; McCarthy, M. I.; Pedersen, O.; Schwenk, J. M.; Adamski, J.; De Masi, F.; Tsirigos, K. D.; Brunak, S.; Vinuela, A.; Mahajan, A.; McDonald, T. J.; Kokkola, T.; Vangipurapu, J.; Cederberg, H.; Laakso, M.; Rutters, F.; Elders, P. J. M.; Koopman, A. D. M.; Beulens, J. W.; Ridderstrale, M.; Hansen, T. H.; Allin, K. H.; Hansen, T.; Vestergaard, H.; Mari, A.; for the IMI DIRECT (...) Diabetes
  Differences in glucose metabolism among categories of prediabetes have not been systematically investigated. In this longitudinal study, participants (N = 2,111) underwent a 2-h 75-g oral glucose tolerance test (OGTT) at baseline and 48 months. HbA1c was also measured. We classified (...)
• 16:58
  Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1 - Guo, Z.; Zhang, Y.; Liu, C.; Youn, J. Y.; Cai, H. Diabetes
  We have previously demonstrated a novel role of bone morphogenic protein 4 (BMP4) in inducing NOX1-dependent endothelial nitric oxide synthase (eNOS) uncoupling, endothelial dysfunction, and inflammatory activation in type 2 diabetes mellitus (T2DM). However, how BMP4 activates NOX1 and whether (...)
• 16:58
  LTB4-Driven Inflammation and Increased Expression of ALOX5/ACE2 During Severe COVID-19 in Individuals With Diabetes - Bonyek-Silva, I.; Machado, A. F. A.; Cerqueira-Silva, T.; Nunes, S.; Silva Cruz, M. R.; Silva, J.; Santos, R. L.; Barral, A.; Oliveira, P. R. S.; Khouri, R.; Serezani, C. H.; Brodskyn, C.; Caldas, J. R.; Barral-Netto, M.; Boaventura, V.; Tavares, N. M. Diabetes
  Diabetes is a known risk factor for severe coronavirus disease 2019 (COVID-19), the disease caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is a lack of knowledge about the mechanisms involved in the evolution of COVID-19 in individuals (...) -- Diabetes and COVID-19
• 16:58
  Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes - Cibi, D. M.; Sandireddy, R.; Bogireddi, H.; Tee, N.; Ghani, S. A. B. A.; Singh, B. K.; Mackman, N.; Singh, M. K.; Singh, A. Diabetes
  Patients with diabetes have an increased risk of heart failure (HF). Diabetes is highly prevalent in HF with preserved ejection fraction (HFpEF), which is on the rise worldwide. The role of diabetes in HF is less established, and available treatments for HF are not effective in patients with (...)
• 16:58
  Vaccination Against Receptor for Advanced Glycation End Products Attenuates the Progression of Diabetic Kidney Disease - Azegami, T.; Nakayama, T.; Hayashi, K.; Hishikawa, A.; Yoshimoto, N.; Nakamichi, R.; Itoh, H. Diabetes
  Effective treatment of diabetic kidney disease (DKD) remains a large unmet medical need. Within the disease’s complicated pathogenic mechanism, activation of the advanced glycation end products (AGEs)–receptor for AGE (RAGE) axis plays a pivotal role in the development and progression of DKD. To (...)
• 16:58
  Erratum. NKG2D Signaling Within the Pancreatic Islets Reduces NOD Diabetes and Increases Protective Central Memory CD8+ T-Cell Numbers. Diabetes 2020;69:1749-1762 - Trembath, A. P.; Krausz, K. L.; Sharma, N.; Gerling, I. C.; Mathews, C. E.; Markiewicz, M. A. Diabetes
• 16:58
  Erratum. A High-Fat Diet Attenuates AMPK alpha1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577-588 - Yan, C.; Tian, X.; Li, J.; Liu, D.; Ye, D.; Xie, Z.; Han, Y.; Zou, M.-H. Diabetes
• 16:58
  Issues and Events Diabetes

Stroke https://www.ahajournals.org/

• 11:00
  Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project - Helen Kim Kelly D. Flemming Jeffrey A. Nelson Avery Lui Jennifer J. Majersik Michael Dela Cruz Joseph Zabramski Odilette Trevizo Giuseppe Lanzino Atif Zafar Michel Torbey Marc C. Mabray Myranda Robinson Jared Narvid Janine Lupo Richard E. Thompson Daniel F. Hanley Nichol McBee Kevin Treine Noeleen Ostapkovich Agnieszka Stadnik Kristina Piedad Nicholas Hobson Timothy Carroll Abdallah Shkoukani Julián Carrión-Penagos Carolina Mendoza-Puccini James I. Koenig Issam Awad Center for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California, San Francisco. (...) Stroke
  Stroke, Ahead of Print. Background and Purpose:Brain cavernous angiomas with symptomatic hemorrhage (CASH) have a high risk of neurological disability from recurrent bleeding. Systematic assessment of baseline features and multisite validation of novel magnetic resonance imaging biomarkers are (...) (Stroke)
• 11:00
  Phenotypes of Chronic Covert Brain Infarction in Patients With First-Ever Ischemic Stroke: A Cohort Study - Jan Vynckier Johannes Kaesmacher Joanna Marguerite Wardlaw Laurent Roten Morin Beyeler Nebiyat Filate Belachew Lorenz Grunder David Julian Seiffge Simon Jung Jan Gralla Tomas Dobrocky Mirjam Rachel Heldner Ulrike Prange Martina Béatrice Goeldlin Marcel Arnold Urs Fischer Thomas Raphael Meinel Department of Neurology, Inselspital, Bern University Hospital, and University of Bern, Switzerland. (J.V., M.B., D.J.S., S.J., M.R.H., U.P., M.G., M.A., U.F., T.R.M.) Department of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, and University of Bern, (...) Stroke
  Stroke, Ahead of Print. Background and Purpose:The aim of this study was to assess the rate of chronic covert brain infarctions (CBIs) in patients with acute ischemic stroke (AIS) and to describe their phenotypes and diagnostic value.Methods:This is a single-center cohort study including 1546 (...) (Stroke)
• 11:00
  Mucormycosis Epidemic and Stroke in India During the COVID-19 Pandemic - M.V. Padma Srivastava Venugopalan Y. Vishnu Awadh Kishor Pandit Department of Neurology, All India Institute of Medical Sciences (AIIMS), New Delhi. Stroke
  Stroke, Ahead of Print. (Stroke)
• 11:00
  Reporting of Results by Sex in Randomized Controlled Trials of Acute Stroke Therapies (2010–2020) - Julia Pudar Brent Strong Virginia J. Howard Mathew J. Reeves Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing (J.P., B.S., M.J.R.). Department of Epidemiology, University of Alabama at Birmingham (V.J.H.). Stroke
  Stroke, Ahead of Print. Background and Purpose:When reporting primary results from randomized controlled trials, recommendations include reporting results by sex. We reviewed the reporting of results by sex in contemporary acute stroke randomized controlled trials.Methods:We searched MEDLINE (...) (Stroke)