00:00The randomized controlled trial (NAVKIDS2) of a patient navigator program created for children with chronic kidney disease. -
Germaine Wong, Chandana Guha, Kylie-Ann Mallitt, Anita van Zwieten, Rabia Khalid, Anna Francis, Allison Jaure, Siah Kim, Armando Teixeira-Pinto, Martha Aquino, Amelie Bernier-Jean, David W. Johnson, Deirdre Hahn, Donna Reidlinger, Elizabeth G. Ryan, Fiona Mackie, Hugh McCarthy, Julie Varghese, Charani Kiriwandeniya, Kirsten Howard, Nicholas Larkins, Luke Macauley, Amanda Walker, Martin Howell, Patrina Caldwell, Reginald Woodleigh, Shilpa Jesudason, Simon Carter, Sean Kennedy, Stephen Alexander, Steve McTaggart, Jonathan C. Craig, Carmel M. Hawley, NAVKIDS2 trial steering committee
Kidney Int
Patient navigators enable adult patients to circumnavigate complex health systems, improving access to health care and outcomes. Here, we aimed to evaluate the effects of a patient navigation program in children with chronic kidney disease (CKD). In this multi-center, randomized controlled (…) (Kidney International (2024))
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A 74-year-old female patient, at 9 years post mitral and tricuspid valve repairs with C-shaped annuloplasty rings, presented with proteinuria (2+) and anemia (Hb 97 g/l), and elevated lactate dehydrogenase levels at 845 U/L (reference range: 120–250 U/L), indicative of intravascular hemolysis. (…) (Kidney International 106, 1 (2024))
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A 58-year-old female patient was referred for solitary kidney management. She was born following a full-term pregnancy, with a weight of 2.2 kg. Her medical history included the following: (i) “Y-shaped metacarpals” and postaxial polydactyly (15 fingers in toto) bilaterally operated (Figure 1); (…) (Kidney International 106, 1 (2024))
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Invasive fungal infections number up to 1,000,000 cases per year,1 and an increasing number exhibit multidrug resistance. Amphotericin B has been an important tool in fighting these infections ever since the 1950s when it was first isolated from the soil of the Orinoco basin in Venezuela.2 (…) (Kidney International 106, 1 (2024))
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Atrial fibrillation (AF) is the most common cardiac arrhythmia, currently affecting ?60 million people worldwide, and it is associated with significant morbidity and mortality.1 Chronic kidney disease (CKD) is an independent risk factor for incident and prevalent AF, with a stepwise increase in (…) (Kidney International 106, 1 (2024))
00:00Corrigendum to “Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.” Kidney International 2023;103:115–133 -
Jingyao Li, Xi’ang Sun, Ninghao Yang, Jiayun Ni, Hongyan Xie, Hengjiang Guo, Xin Wang, Li Zhou, Jun Liu, Sijia Chen, Xiaoxia Wang, Yingying Zhang, Chen Yu, Wei Zhang, Limin Lu
Kidney Int
DOI of original article: https://doi.org/10.1016/j.kint.2022.08.022 (Kidney International 106, 1 (2024))
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DOI of original article: 10.1016/j.kint.2022.09.005 (Kidney International 106, 1 (2024))
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A 53-year-old man with type 2 diabetes–related kidney failure underwent cytomegalovirus (CMV)–mismatched (CMV positive to negative), deceased donor kidney transplant in July 2021. He was on a prophylactic dose of valganciclovir until September 2021 when he developed neutropenia, and (…) (Kidney International 106, 1 (2024))
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A 38-year-old woman presented at a peripheral hospital for progressive abdominal pain, nausea, and vomiting. Except for a 7-day course of antibiotic treatment following a dental procedure performed a few days before symptom onset, she had not been on any medication. Her medical history was not (…) (Kidney International 106, 1 (2024))
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(Kidney International 106, 1 (2024))
00:00Erratum to “An update on clinical presentation and responses to therapy of patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH).” Kidney International 2023;105:1058–1076 -
Zewu Zhu, Bryan Bo-Ran Ho, Alyssa Chen, James Amrhein, Andreea Apetrei, Thomas Oliver Carpenter, Marise Lazaretti-Castro, Juan Manuel Colazo, Kathryn McCrystal Dahir, Michaela Geßner, Evgenia Gurevich, Cathrine Alsaker Heier, Jill Hickman Simmons, Tracy Earl Hunley, Bernd Hoppe, Christina Jacobsen, Anne Kouri, Nina Ma, Sachin Majumdar, Arnaud Molin, Natalie Nokoff, Susan M. Ott, Helena Gil Peña, Fernando Santos, Peter Tebben, Lisa Swartz Topor, Yanhong Deng, Clemens Bergwitz
Kidney Int
The publisher regrets that the definition of het-post (post-treatment levels of het carriers) was not included in the legends of Figure 3 and Supplementary Figure S3, and that descriptions of upper limit (%UL) and/or z-score were not included in the legends of Supplementary Figures S2–S4, S6, (…) (Kidney International 106, 1 (2024))
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Glomerular issues and affected podocytes are at the origin of 80% of chronic kidney disease cases. Thus, acquiring a deeper understanding in this domain is necessary to halt progressive kidney damage. In this study, the authors investigated the harmful impact of podocyte-cleaved soluble retinoic (…) (Kidney International 106, 1 (2024))
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New evidence indicates potential benefit of genomics to illuminate nonkidney monogenic morbidity and mortality risk among kidney transplant recipients. This might be of direct relevance to an equivalent proportion of patients to those who harbor a monogenic kidney disease. Further evidence and (…) (Kidney International 106, 1 (2024))
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Verma et al. (Ann Intern Med. 2024;177:467–475.) (Kidney International 106, 1 (2024))
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Asowata and colleagues studied deceased donor transplant kidneys with impaired kidney function as a model of acute and chronic kidney injury using an integrated multi-omic approach. RNA sequencing demonstrated that T cell and macrophage tissue infiltration associated with changes in both donors’ (…) (Kidney International 106, 1 (2024))
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Chronic hemodialysis patients exhibit an excessive cardiovascular risk and a marked increase in both thromboembolism and bleeding episodes. Factor XI inhibition may provide anticoagulation, with a low risk of bleeding, and several factor XI inhibitors, including fesomersen, an antisense (…) (Kidney International 106, 1 (2024))
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(Kidney International 106, 1 (2024))
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(Kidney International 106, 1 (2024))