25 June

J Am Med Assoc (JAMA) https://jama.jamanetwork.com/

• 02:00
  Are Patients With Cancer Best Managed in a Clinical Trial J Am Med Assoc (JAMA)
  This Viewpoint analyzes how the NCCN’s boxed statement that all cancer is best managed in a clinical trial cannot be applied to all patients and calls for its removal from its clinical practice guidelines.
• 02:00
  Study Participants, Future Patients, and Outcomes That Matter in Cancer Clinical Trials J Am Med Assoc (JAMA)
  Randomized clinical trials (RCTs) define the efficacy of new cancer treatments and drive changes in clinical practice. Although the role of RCTs in generating knowledge is universally accepted, the often-cited benefits of trial participation for individual patients is open for debate. The trial (…)
• 02:00
  Survival Benefit Associated With Participation in Clinical Trials of Anticancer Drugs J Am Med Assoc (JAMA)
  This systematic review and meta-analysis examines whether patient participation in cancer trials is associated with greater survival benefit compared with routine care.
• 02:00
  Pediatric Phoenix Sepsis Score Challenges J Am Med Assoc (JAMA)
  To the Editor We think the Phoenix Sepsis Score is an important achievement as a pediatric sepsis definition, which considers the performance and application of the score in lower-resource settings. The score was developed in response to clinician survey results that emphasized that the updated (…)
• 02:00
  Current Comment J Am Med Assoc (JAMA)
• 02:00
  Industry Payments to Physicians Endorsing Drugs and Devices on a Social Media Platform J Am Med Assoc (JAMA)
  This study evaluates adherence to industry and professional standards among physicians endorsing drugs and devices on a social media platform.
• 02:00
  Therapies to Decrease Severe Respiratory Syncytial Virus Illness J Am Med Assoc (JAMA)
  This JAMA Insights discusses the use of monoclonal antibodies or protein-based vaccines to help prevent severe RSV infection in infants, children, and older adults.
• 02:00
  Updated Absolute Mortality Rates of Lupus J Am Med Assoc (JAMA)
  The Review titled “Systemic Lupus Erythematosus: A Review,” published in the May 7, 2024, issue of JAMA, has been updated to provide the absolute mortality rates by sex, age, race, and geographic region in the Prognosis section. This article was corrected online.
• 02:00
  To Fix Burnout, New Initiatives Go Beyond Worker Resilience J Am Med Assoc (JAMA)
  This Medical News article discusses the great resignation in health care and new efforts to create a sustainable medical workforce in the US.
• 02:00
  What Anger Does to the Blood Vessels J Am Med Assoc (JAMA)
  This Medical News article discusses a randomized clinical trial that investigated the effects of negative emotions on blood vessel dilation.
• 02:00
  Private Equity Owns 25% of Mental Health Facilities in Some States J Am Med Assoc (JAMA)
  The number of mental health and substance use facilities that are owned by private equity firms has steadily increased in the US over the past 10 years, according to findings from about 26 500 facilities nationwide between 2012 and 2023. About 6% of all mental health facilities were private (…)
• 02:00
  Too Few Clinicians Screen Patients for Intimate Partner Violence J Am Med Assoc (JAMA)
  More than 40% of women will experience intimate partner violence during their lives, as will more than one-quarter of men. That’s why the US Preventive Services Task Force (USPSTF) recommends screening all women of reproductive age for intimate partner violence, which can include physical, (…)
• 02:00
  Stark Differences Exist in Health, Disability Between Males and Females J Am Med Assoc (JAMA)
  Substantial differences existed in the way the 20 leading causes of disease affected females and males worldwide, a study involving data from 1990 to 2021 found.
• 02:00
  Study: 2 APOE4 Copies May Indicate Genetic Form of Alzheimer Disease J Am Med Assoc (JAMA)
  Almost all people who inherited 2 identical copies of the APOE4 gene variant had abnormally high levels of amyloid in their cerebrospinal fluid and brain by age 65 years, according to a new study that combined data from more than 3200 brain donors and about 10 000 participants with clinical data.
• 02:00
  FDA Announces Increased Oversight of Some Diagnostic Laboratory Tests J Am Med Assoc (JAMA)
  The US Food and Drug Administration (FDA) will begin supervising laboratory-developed tests more closely due to concerns that they do not always provide accurate results, the agency recently announced.
• 02:00
  Outpatient Adverse Events More Common, Preventable Than Expected J Am Med Assoc (JAMA)
  About 7% of people seen in an outpatient setting had at least 1 adverse event, according to findings from about 3100 patients from 11 sites in Massachusetts. The majority of these patients—64%—experienced drug-related adverse events, such as allergic reactions. About 15% of affected patients (…)
• 02:00
  Cytisinicline More Than Doubled Chances of Quitting E-Cigarettes J Am Med Assoc (JAMA)
  Millions of young people currently use e-cigarettes, according to recent data. However, there are few evidence-backed strategies to help people stop vaping. Now, a double-blind randomized study published in JAMA Internal Medicine suggests that a drug known as cytisinicline might also help curb (…)
• 02:00
  Poll: Health-Related Costs Top Older Adults’ Concerns J Am Med Assoc (JAMA)
  When asked about their feelings on more than 20 topics, older adults listed various health-related costs as their top 6 concerns, based on data from about 3400 respondents to the University of Michigan’s National Poll on Healthy Aging. The majority of respondents aged 50 years or older were (…)
• 02:00
  WHO: As Mpox Outbreaks Continue, Cases May Be Underestimated J Am Med Assoc (JAMA)
  About 2 years after the global mpox outbreak began, the World Health Organization (WHO) provided updated numbers of mpox cases and revised vaccine recommendations in a new situation report. From 2022 through March 2024, more than 95 200 people have developed mpox infections and 185 patients have (…)
• 02:00
  JAMA J Am Med Assoc (JAMA)
• 02:00
  Audio Highlights J Am Med Assoc (JAMA)
  Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.
• 02:00
  Benefit of RAS Blockade in Heart Failure by Race J Am Med Assoc (JAMA)
  This meta-analysis assesses whether Black patients with heart failure and reduced ejection fraction respond differently than patients of other races to renin-angiotensin system (RAS) blockade by examining individual patient data from randomized clinical trials.
• 02:00
  Needlework at the Hospital J Am Med Assoc (JAMA)
  This is the beginning of something for yourself for once, a summer afghan, a simple little throw for meditation,
• 02:00
  Mimesis: Poetry and Imitating Medicine J Am Med Assoc (JAMA)
  Mimesis in poetry is the imitation or re-creation of reality using art. Thinkers ranging from Aristotle to Adorno have wondered at this human capacity to symbolize, and how it helps us make our own sense of, and express to others, both our external and internal worlds. In the poem “Needlework at (…)
• 02:00
  Review: Chronic Pruritus J Am Med Assoc (JAMA)
  This narrative review summarizes current evidence regarding diagnosis and treatment of chronic pruritus.
• 02:00
  Evidence Against Use of Nitrogen for the Death Penalty J Am Med Assoc (JAMA)
  This Viewpoint discusses the recent use of forced nitrogen inhalation as capital punishment in Alabama and describes the body of evidence indicating that forced nitrogen inhalation is an inhumane practice.
• 02:00
  Pediatric Phoenix Sepsis Score Challenges J Am Med Assoc (JAMA)
  To the Editor We read with great interest the article “International Consensus Criteria for Pediatric Sepsis and Septic Shock” and commend the authors for their dedication to standardizing and improving the care of children with sepsis. By using an empirical approach in a global cohort of (…)
• 02:00
  Pediatric Phoenix Sepsis Score Challenges—Reply J Am Med Assoc (JAMA)
  In Reply Ms Msefula and colleagues raise an important point regarding inclusion of tests and therapies in the Phoenix Sepsis Score that, based on the global survey performed by the Pediatric Sepsis Definition Task Force, may not be universally available. Msefula and colleagues have an associated (…)
• 02:00
  Long-Term Outcomes From Prostate Cancer Active Surveillance J Am Med Assoc (JAMA)
  This prospective, multicenter cohort study evaluates the long-term outcomes of men diagnosed with favorable-risk prostate cancer managed with protocol-directed active surveillance, including regular biopsies and prostate-specific antigen screening, from 2008 to 2022.
• 02:00
  Patient Information: Age-Related Macular Degeneration J Am Med Assoc (JAMA)
  This JAMA Patient Page describes age-related macular degeneration development and progression; symptoms and risk factors; and diagnosis, monitoring, and treatment.
• 02:00
  The Clinic Visit J Am Med Assoc (JAMA)
  In this narrative medicine essay, a surgical oncologist reflects on his 30-year practice and the care he receives for his leukemia, understanding how vital the relationships and discourse with the care team are for his recovery.
• 02:00
  The Texas Medical Board and the Futility of Medical Exceptions to Abortion Bans J Am Med Assoc (JAMA)
  This Viewpoint describes the failure of yet another state institution to generate meaningful guidance about medical exceptions to abortion bans.
• 02:00
  Accounting for Competing Risks in Clinical Research J Am Med Assoc (JAMA)
  This JAMA Guide to Statistics and Methods article discusses accounting for competing risks in clinical research.
• 02:00
  Ransomware Attacks, ED Visits and Inpatient Admissions in Targeted and Nearby Hospitals J Am Med Assoc (JAMA)
  This case-control study analyzes disruptive ransomware attacks against hospitals in California from 2014 to 2020 and emergency department (ED) and inpatient admissions in attacked and nearby hospitals.

18 June

J Am Med Assoc (JAMA) https://jama.jamanetwork.com/

• 02:00
  Advancing Access to Cell and Gene Therapies in Medicaid J Am Med Assoc (JAMA)
  This Viewpoint presents the components of the payment model and the implementation challenges among the Center for Medicare and Medicaid Innovation, state Medicaid agencies, patients, and manufacturers.
• 02:00
  FTC Oversight of the Pharmaceutical Industry J Am Med Assoc (JAMA)
  High drug prices in the US are a serious problem for both patients and the health care system. Prices of branded drugs are driven higher by monopoly dynamics: patents and other exclusive marketing rights allow companies to increase prices and restrict supply. Firms earn extraordinary profits (…)
• 02:00
  Krill Oil for Knee Osteoarthritis J Am Med Assoc (JAMA)
  This randomized clinical trial assesses the effect of krill oil supplementation vs placebo on knee pain improvement in patients with knee osteoarthritis, significant knee pain, and effusion-synovitis.
• 02:00
  A Good Prognosis J Am Med Assoc (JAMA)
  These are not the final few months of my life, not the last bowl of salad I add a few spoons of tuna and mayo to. I’m not going to die on a date printed in the calendar that hangs on my fridge with cheesy pictures of Yosemite and captions like Bike to Work Day. I can sit here at the kitchen (…)
• 02:00
  Time to IVT Treatment and Functional Outcomes in Acute Ischemic Stroke—Reply J Am Med Assoc (JAMA)
  In Reply We thank Drs Sedghi and Siepmann for their comments. Indeed, all trials included in our individual participant meta-analysis enrolled only patients directly presenting at thrombectomy-capable stroke centers. Hence, the data presented in our study are applicable only to this exact (…)
• 02:00
  Chronic Chagas Disease in the US J Am Med Assoc (JAMA)
  This JAMA Insights provides recommendations for Chagas disease screening, diagnosis, and management in the US
• 02:00
  Dispensing of Glucagon-Like Peptide-1 Receptor Agonists to Adolescents and Young Adults, 2020-2023 J Am Med Assoc (JAMA)
  This study uses data from US retail pharmacies to assess national GLP-1RA dispensing to adolescents and young adults from 2020-2023.
• 02:00
  Time to IVT Treatment and Functional Outcomes in Acute Ischemic Stroke J Am Med Assoc (JAMA)
  To the Editor A recent individual patient data meta-analysis of 6 randomized trials found that the beneficial effect of intravenous thrombolysis (IVT) before thrombectomy in patients with anterior-circulation large-vessel occlusion diminished with time from onset of stroke symptoms to (…)
• 02:00
  Social Isolation and Loneliness in Older Adults J Am Med Assoc (JAMA)
  This JAMA Patient Page discusses social isolation and loneliness as important public health concerns, especially among older adults.
• 02:00
  The Other Side of the Curtain J Am Med Assoc (JAMA)
  In this narrative medicine essay, a newly minted pediatric critical care physician learns firsthand what holistic medical care is from the love and attention she received during a hospitalization for mediastinal lymphoma.
• 02:00
  Heard but Excluded: A Language Manifesto J Am Med Assoc (JAMA)
  This Viewpoint discusses dismantling language barriers via multipronged approaches grounded in innovation, human-centered design, and systems thinking in 3 key areas.
• 02:00
  Phoenix Criteria for Pediatric Sepsis and Septic Shock J Am Med Assoc (JAMA)
  To the Editor We read Dr Sanchez-Pinto and colleagues’ study with interest, but we are concerned that the final Phoenix 4-organ model does not include acute kidney injury (AKI) assessment. Additionally, the Phoenix 8-organ model used only a single serum creatinine threshold. Despite inclusion of (…)
• 02:00
  Phoenix Criteria for Pediatric Sepsis and Septic Shock—Reply J Am Med Assoc (JAMA)
  In Reply We are grateful to Dr Thadani and colleagues for their interest in our work and applaud their efforts to improve outcomes from AKI around the world. We agree that AKI is important to assess and treat in children with sepsis in any environment and that children in some less-resourced (…)
• 02:00
  Shingles Vaccination in Medicare Part D After Inflation Reduction Act Elimination of Cost Sharing J Am Med Assoc (JAMA)
  This cross-sectional study uses data from retail pharmacies to examine shingles vaccine uptake among Medicare Part D beneficiaries following an IRA policy to eliminate cost sharing.
• 02:00
  How AI Will Augment Radiologists J Am Med Assoc (JAMA)
  This Medical News article is an interview with Saurabh Jha, a cardiothoracic radiologist and an associate professor of radiology at the University of Pennsylvania, and JAMA Editor in Chief Kirsten Bibbins-Domingo.
• 02:00
  Public Health Preparedness and Response to Avian Influenza A(H5N1) Viruses J Am Med Assoc (JAMA)
  US public health preparedness and response to highly pathogenic avian influenza A(H5N1) viruses are assessed in this survey study conducted by the CDC.
• 02:00
  Congress, the Doctor J Am Med Assoc (JAMA)
  Without a dissenting vote, the House of Delegates of the American Medical Association adopted last week a resolution calling on the Board of Trustees to use its best endeavors to have repealed such sections of the national prohibition acts as may interfere with the proper relation between the (…)
• 02:00
  Monoclonal Antibody Protected Majority of Children From Malaria J Am Med Assoc (JAMA)
  Current strategies to protect children from malaria—administration of new RTS,S/AS01 or R21/Matrix-M vaccines as well as seasonal medications—require about 20 health care visits by the time a child reaches age 5 years. However, an approach involving the annual administration of a monoclonal (…)
• 02:00
  HHS Commits Millions to Improving Maternal, Infant Health J Am Med Assoc (JAMA)
  The proportion of people who die while pregnant or within 42 days after their pregnancy ends has been steadily increasing in the US. Now, updated numbers from the National Vital Statistics System indicate promising trends in maternal mortality rates. About 22 people per 100 000 live births died (…)
• 02:00
  Lower Dose of Mpox Vaccine Was Safe, Effective J Am Med Assoc (JAMA)
  Intradermal injections that were one-fifth of the standard mpox vaccine dose generated antibody responses equivalent to those of subcutaneous injections of the standard dose at 6 weeks, based on results from 225 US adults aged 18 to 50 years. No participants experienced serious adverse events (…)
• 02:00
  New Drug for UTIs Gets the Greenlight J Am Med Assoc (JAMA)
  The US Food and Drug Administration recently approved pivmecillinam, sold as Pivya, for uncomplicated urinary tract infections (UTIs) in females aged 18 years or older with no structural abnormalities of their urinary tract. UTIs affect about 50% of females at some point during their life, the (…)
• 02:00
  Progress in Heart Failure Deaths Reversed Over Past Decade J Am Med Assoc (JAMA)
  Although heart failure mortality rates fell between 1999 and 2012, the proportion of people dying from the condition in the US has increased in recent years, according to a study published in JAMA Cardiology. By 2021, the heart failure mortality rate was higher than in 1999, signaling that (…)
• 02:00
  Federal Trade Commission Bans Noncompete Clauses J Am Med Assoc (JAMA)
  Up to 45% of physicians are subject to noncompete clauses, contractual requirements that can prevent them from changing jobs, which can limit competition and access to care, according to the American Medical Association. However, employers will no longer be allowed to enforce noncompete clauses (…)
• 02:00
  Blood Pressure Drugs Linked to More Fractures, Falls in VA Nursing Homes J Am Med Assoc (JAMA)
  Long-term Veterans Health Administration (VA) nursing home residents who started new medications to treat high blood pressure were more than twice as likely to experience a fracture than those who did not, according to a cohort study involving more than 29 600 VA participants, almost all male, (…)
• 02:00
  Monoclonal Antibody Authorized to Protect At-Risk People From COVID-19 J Am Med Assoc (JAMA)
  The US Food and Drug Administration (FDA) granted emergency use authorization to pemivibart, marketed as Pemgarda, to protect people who are immunocompromised from COVID-19. Pemivibart is the only long-acting monoclonal antibody available in the US for preexposure prophylaxis after the FDA (…)
• 02:00
  Microneedle Vaccine Patches Generated Immune Response in Children J Am Med Assoc (JAMA)
  People who received a microneedle patch that delivered a measles and rubella vaccine mounted immune responses that were equivalent to those vaccinated via subcutaneous injection, according to data from a randomized clinical trial involving 285 participants from The Gambia, including 240 toddlers (…)
• 02:00
  Maintenance of Certification’s Value to Patients and Physicians—Reply J Am Med Assoc (JAMA)
  In Reply We appreciate the Letter by Drs Stern and Hafferty about our recent Viewpoint, which gave priority to highlighting the large and growing body of evidence that patients of physicians who demonstrate more medical knowledge have better prognoses on a host of important outcomes. In doing (…)
• 02:00
  Federal Trade Commission Actions on Prescription Drugs, 2000-2022 J Am Med Assoc (JAMA)
  This Special Communication examines the Federal Trade Commission’s policy and legal actions related to alleged misconduct, consolidation, and anticompetitive behavior in the pharmaceutical market between 2000 and 2022.
• 02:00
  Blood Testing for Phosphatidylethanol J Am Med Assoc (JAMA)
  A 36-year-old man with obesity and dyslipidemia presented with elevated liver enzymes following a liver transplant to treat acute-on-chronic liver failure due to alcohol-associated hepatitis. What would you do next?
• 02:00
  Risks of Harm in Alzheimer Disease by Amyloid Lowering J Am Med Assoc (JAMA)
  This Viewpoint discusses how data gaps in published research impede clinicians’ ability to clearly discuss the risks and benefits of amyloid-lowering drugs for treating Alzheimer disease.
• 02:00
  Harnessing the Electronic Health Record to Improve Empiric Antibiotic Prescribing J Am Med Assoc (JAMA)
  Approximately half of hospitalized adults in the US receive antibiotics, with pneumonia and urinary tract infection (UTI) being the 2 most frequent indications. Estimates suggest about 30% of all antibiotics prescribed in US hospitals are either unnecessary or suboptimal, and extended-spectrum (…)
• 02:00
  Stewardship Prompts to Improve Antibiotic Selection for Pneumonia J Am Med Assoc (JAMA)
  This clinical trial examines the effect of an antibiotic stewardship bundle (education, feedback, and real-time multidrug-resistant organism risk-based CPOE prompts) vs routine stewardship on antibiotic selection during the first 3 hospital days in adults with pneumonia.
• 02:00
  Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection J Am Med Assoc (JAMA)
  This clinical trial evaluates whether computerized provider order entry prompts providing patient- and pathogen-specific multidrug-resistant organism risk estimates could reduce use of empiric extended-spectrum antibiotics for treatment of urinary tract infections.
• 02:00
  Audio Highlights J Am Med Assoc (JAMA)
  Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.
• 02:00
  JAMA J Am Med Assoc (JAMA)
• 02:00
  Maintenance of Certification’s Value to Patients and Physicians J Am Med Assoc (JAMA)
  To The Editor The American Board of Internal Medicine (ABIM) has an outsized influence as the arbiter of internal medicine physician quality, given the alternatives of minimal state regulations, spotty insurance-based estimates, and random patient-based ratings. A recent Viewpoint responded to (…)

11 June

J Am Med Assoc (JAMA) https://jama.jamanetwork.com/

• 02:00
  Toward More Equitable Breast Cancer Outcomes J Am Med Assoc (JAMA)
  In its revised Recommendation Statement, the US Preventive Services Task Force (USPSTF) now recommends that all women undergo routine breast cancer screening every other year beginning at age 40 years. This is an adjustment from the 2016 recommendation for all women to start at age 50 and for (…)
• 02:00
  USPSTF Report: Collaborative Modeling to Compare Breast Cancer Screening Strategies J Am Med Assoc (JAMA)
  This modeling study uses Cancer Intervention and Surveillance Modeling Network models and national data on breast cancer incidence, mammography performance, treatment effects, and other-cause mortality in US women without previous cancer diagnoses to estimate outcomes of various mammography (…)
• 02:00
  Apixaban to Prevent Recurrence After Cryptogenic Stroke J Am Med Assoc (JAMA)
  To the Editor A recent clinical trial demonstrated that apixaban did not significantly reduce recurrent stroke risk compared with aspirin in patients with cryptogenic stroke and evidence of atrial cardiopathy without atrial fibrillation. However, we had some concerns about this study. First, it (…)
• 02:00
  Apixaban to Prevent Recurrence After Cryptogenic Stroke J Am Med Assoc (JAMA)
  To the Editor The recent Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke (ARCADIA) trial did not demonstrate superiority of apixaban over aspirin for secondary prevention in patients with cryptogenic stroke and atrial cardiopathy. In this study, atrial (…)
• 02:00
  Apixaban to Prevent Recurrence After Cryptogenic Stroke—Reply J Am Med Assoc (JAMA)
  In Reply In response to our recent article, Dr Chi and colleagues raise an important point regarding uncertainty about optimal biomarkers of atrial cardiopathy. Compared with ARCADIA patients who qualified for enrollment in our study only by the NT-proBNP criterion, those who qualified by only (…)
• 02:00
  Poetry and the Meaning of Care J Am Med Assoc (JAMA)
  Health care is becoming more and more distanced. Clinicians must overcome not just mountains of data, burdensome electronic health records, and ever-increasing numbers of machines that separate us from patients, but more recently also navigate telemedicine and AI-driven chatbots. (…)
• 02:00
  Can Cardiovascular Risk Assessment Be Improved in the 21st Century? J Am Med Assoc (JAMA)
  Cardiovascular risk assessment has become an essential part of preventive strategies designed to target risk factor interventions and has contributed to dramatic reductions in cardiovascular disease mortality during the past 60 years in the US and other countries. Beginning in the 1960s, (…)
• 02:00
  Autoantibody Profile Emerged Years Before Multiple Sclerosis Diagnosis J Am Med Assoc (JAMA)
  About 10% of people with multiple sclerosis (MS) had an autoantibody signature that was present at least 5 years before symptoms, according to an analysis of blood samples from 500 military service members. Researchers collected the first sample an average of 5 years before some participants (…)
• 02:00
  Patients Treated by Female Physicians Had Better Mortality Rates J Am Med Assoc (JAMA)
  Hospitalized patients in the US tended to have a lower chance of dying or being readmitted within 30 days when they were treated by female physicians rather than male clinicians, a recent study published in Annals of Internal Medicine found. The difference in outcomes for patients examined by (…)
• 02:00
  The Challenge of the Computer J Am Med Assoc (JAMA)
  The average physician is unlikely to build a computer in his basement from a kit. But the principles of computer analysis are not difficult to master. Evidence of the growing importance of these complex electronic machines is found in the announcement that the potential of the computer in (…)
• 02:00
  AI-Generated Clinical Summaries J Am Med Assoc (JAMA)
  To the Editor In their recent Viewpoint, Dr Goodman and colleagues examined artificial intelligence (AI)–generated clinical summaries and identified concerns regarding variability, bias, and single-word errors in their AI summaries generated through the ChatGPT model. However, it must be noted (…)
• 02:00
  AI-Generated Clinical Summaries—Reply J Am Med Assoc (JAMA)
  In Reply We thank Ms Chen and Dr Thornton for their interest in our Viewpoint examining potential benefits and challenges of AI-generated clinical summaries. We fully agree that future studies should evaluate how AI summaries influence physician decision-making and clinical outcomes. We (…)
• 02:00
  Antipsychotics for Dementia Tied to More Serious Harms Than Expected J Am Med Assoc (JAMA)
  Prior research has suggested that antipsychotic drugs might be overprescribed for people with dementia, despite known risks of stroke and sudden cardiac death. Now, findings from a new study in The BMJ indicate that the range of serious adverse outcomes associated with antipsychotics in these (…)
• 02:00
  WHO Updates Terminology for Pathogens That Spread Through the Air J Am Med Assoc (JAMA)
  A multiyear global collaboration among public health agencies has led to new terminology for pathogens such as SARS-CoV-2 that can spread through the air, the World Health Organization (WHO) announced. The report by the WHO and partners, including the US Centers for Disease Control and (…)
• 02:00
  Pregnancy Complications Tied to Higher Risk of Death Decades Later J Am Med Assoc (JAMA)
  Pregnant people who experienced adverse pregnancy outcomes had up to a 50% increased risk of dying from any cause up to 46 years after giving birth, according to data from a cohort study involving about 2.2 million participants from Sweden who gave birth between 1973 and 2015. Cardiovascular and (…)
• 02:00
  New HHS Rule Strengthens Privacy Around US Reproductive Care J Am Med Assoc (JAMA)
  The US Department of Health and Human Services (HHS) recently announced a final rule that increases privacy protections for people seeking legal reproductive care, such as an abortion, either in their home state or by traveling to another one. The modification to the Health Insurance Portability (…)
• 02:00
  Changes to Medicare, Medicaid Coverage Could Cause Thousands of Deaths J Am Med Assoc (JAMA)
  Some policymakers have suggested increasing the eligibility age for Medicare and implementing work requirements for Medicaid coverage to reduce US health care costs. However, a recent analysis involving data projections from the Census Bureau suggests that the proposed changes would cost (…)
• 02:00
  CMS Finalizes Staffing Minimum Requirements for Nursing Homes J Am Med Assoc (JAMA)
  The US Centers for Medicare & Medicaid Services (CMS) recently finalized a rule establishing the first minimum staffing requirements for nursing homes after an earlier version was proposed last September. The new rule will “hold nursing homes accountable for providing safe and (…)
• 02:00
  Late-Stage Cancer End Points to Speed Cancer Screening Clinical Trials—Not So Fast J Am Med Assoc (JAMA)
  In this issue of JAMA, Feng et al studied whether late-stage cancer (ie, stage III or stage IV cancer), rather than cancer-specific mortality, was an acceptable alternative end point in clinical trials of cancer screening. The authors analyzed 41 clinical trials conducted in Europe, North (…)
• 02:00
  USPSTF Recommendation: Screening for Breast Cancer J Am Med Assoc (JAMA)
  This 2024 Recommendation Statement from the US Preventive Services Task Force recommends biennial screening mammography for women aged 40 to 74 years (B recommendation) and concludes that evidence is insufficient to assess the balance of benefits and harms of screening mammography in women 75 (…)
• 02:00
  Screening for Breast Cancer J Am Med Assoc (JAMA)
  In this JAMA Patient Page, the US Preventive Services Task Force provides a guide to screening for breast cancer.
• 02:00
  USPSTF Review: Screening for Breast Cancer J Am Med Assoc (JAMA)
  This systematic review to support a 2024 US Preventive Services Task Force Recommendation Statement summarizes published evidence on the benefits and harms of screening for breast cancer in adult females.
• 02:00
  The State of State Biomarker Testing Insurance Coverage Laws J Am Med Assoc (JAMA)
  This Viewpoint discusses laws mandating insurance coverage of biomarker testing to broaden access to care for patients with cancer.
• 02:00
  When Is It Best to Begin Mammograms, and How Often? J Am Med Assoc (JAMA)
  This Medical News story discusses new USPSTF recommendations about the timing of screening mammograms.
• 02:00
  Prognostic Value of Cardiovascular Biomarkers in the Population J Am Med Assoc (JAMA)
  This study evaluates the prognostic value of routinely available cardiovascular biomarkers when added to established risk factors in the identification of individuals at high risk for atherosclerotic cardiovascular disease.
• 02:00
  Apixaban to Prevent Recurrence After Cryptogenic Stroke J Am Med Assoc (JAMA)
  To the Editor We have several concerns about the recent trial that examined apixaban for prevention of recurrence after cryptogenic stroke in patients with atrial cardiopathy.
• 02:00
  Mortality in Patients Hospitalized for COVID-19 vs Influenza in Fall-Winter 2023-2024 J Am Med Assoc (JAMA)
  This cohort study evaluates the risk of death in patients hospitalized for COVID-19 or seasonal influenza following the emergence of the JN.1 variant in winter 2023.
• 02:00
  Even Joy J Am Med Assoc (JAMA)
  Since her birth with half a brain The doctors have been kind, So awed by her determination they loan a private Room for the transient child to be and Show the worth of being Even if
• 02:00
  Fosamax Fractures J Am Med Assoc (JAMA)
  This Viewpoint discusses the ongoing lawsuit between plaintiffs who had been affected by atypical femoral fractures while receiving alendronate and the drug manufacturer.
• 02:00
  Cancer Stage Compared With Mortality as End Points in Randomized Clinical Trials of Cancer Screening J Am Med Assoc (JAMA)
  This meta-analysis of 41 randomized clinical trials of cancer screening compares cancer-specific mortality with stage III-IV cancer as end points.
• 02:00
  I Kept Crying J Am Med Assoc (JAMA)
  In this narrative medicine essay, a second-year pediatric resident bears the scars from the terror that descended the moment of her son’s birth at 31 weeks’ gestation, terror relived even after he has come home healthy.
• 02:00
  Combined COVID-19 and Flu Vaccines Could Be Available Next Year J Am Med Assoc (JAMA)
  This Medical News story discusses the development of experimental combination vaccines for adults.
• 02:00
  “Inoculation” to Resist Misinformation J Am Med Assoc (JAMA)
  This JAMA Insights in the Communicating Medicine series explores the concept of “prebunking,” a psychological inoculation technique that could help prevent the spread of misinformation.
• 02:00
  Audio Highlights J Am Med Assoc (JAMA)
  Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.
• 02:00
  JAMA J Am Med Assoc (JAMA)
• 02:00
  Urine-Based Test Could Help Identify Aggressive Prostate Cancer J Am Med Assoc (JAMA)
  A urine-based test involving 18 genes was more accurate at diagnosing high-grade prostate cancer than existing biomarker tests such as blood levels of prostate-specific antigen (PSA), according to a recent study published in JAMA Oncology.

4 June

J Am Med Assoc (JAMA) https://jama.jamanetwork.com/

• 02:00
  Non–HDL-C Levels From Childhood to Adulthood and CVD Events J Am Med Assoc (JAMA)
  This study of individual participant data from 6 pooled cohorts assesses whether resolution of elevated childhood non–high-density lipoprotein cholesterol (non–HDL-C) by adulthood is associated with reduced risk of clinical cardiovascular disease (CVD) events.
• 02:00
  Assessing the Real-World Effectiveness of Immunizations for Respiratory Syncytial Virus J Am Med Assoc (JAMA)
  This Viewpoint discusses recommendations from the US Centers for Disease Control and Prevention for newly licensed immunizations for respiratory syncytial virus in infants, children with high-risk conditions, and older adults.
• 02:00
  A Review of Thyroid Cancer—Reply J Am Med Assoc (JAMA)
  In Reply We appreciate letters about our Review on thyroid cancer. In response to the comments by Drs Beheshtirouy and Shayanfar, the causal association between GLP-1 RA use and thyroid cancer is complex and requires careful consideration of factors that directly or indirectly influence (...)
• 02:00
  A Review of Thyroid Cancer J Am Med Assoc (JAMA)
  To the Editor A recent Review discussed the complexity of thyroid cancer. First, we would like to highlight the importance of distinguishing between benign and malignant thyroid nodules preoperatively.
• 02:00
  A Review of Thyroid Cancer J Am Med Assoc (JAMA)
  To the Editor A recent Review discussed exposure to ionizing radiation as a common risk factor for thyroid cancer. However, it is important to consider additional risk factors for thyroid cancer.
• 02:00
  Substances in Counterfeit Prescription Pills Seized by Law Enforcement, 2017-2022 J Am Med Assoc (JAMA)
  This study examines substances identified during testing of counterfeit prescription pills seized by law enforcement in Rhode Island from 2017 to 2022.
• 02:00
  Thomas, Unsainted J Am Med Assoc (JAMA)
  Again left fingers enter the chest
• 02:00
  Safeguarding Research Using Federal Health Insurance Data J Am Med Assoc (JAMA)
  This Viewpoint discusses the importance of researcher access to federal health care data following a CMS decision to limit the use of physical data and proposes solutions to maintain access and security.
• 02:00
  Fritz Kahn and the Centenary of the Doctor of the Future J Am Med Assoc (JAMA)
  This JAMA Arts and Medicine feature describes ways in which Fritz Kahn shared a prescient and nuanced vision of technology’s role in the patient-physician interaction, a topic of continued interest and relevance today, through his illustrations.
• 02:00
  Denosumab-Associated Severe Hypocalcemia in Dialysis-Dependent Patients—Reply J Am Med Assoc (JAMA)
  In Reply We thank Drs Schoenmakers and Fraser for their comments on our study. We reported the US experience with denosumab administration among dialysis-dependent patients, finding the weighted cumulative incidence of severe hypocalcemia (ie, <7.5 mg/dL or emergent care) at 12 weeks to (...)
• 02:00
  Cardiovascular-Kidney-Metabolic Syndrome Stages in US Adults J Am Med Assoc (JAMA)
  This cross-sectional study assesses the prevalence and temporal evolution of cardiovascular-kidney-metabolic syndrome stages.
• 02:00
  Denosumab-Associated Severe Hypocalcemia in Dialysis-Dependent Patients J Am Med Assoc (JAMA)
  To the Editor We have some concerns about the recent retrospective public health surveillance study of older female dialysis-dependent patients who were treated with denosumab for osteoporosis.
• 02:00
  Best Versions of Ourselves J Am Med Assoc (JAMA)
  In this narrative medicine essay, a lecturer in narrative medicine strives to accept her best self by surmounting the barriers of itchy skin and unsightly red patches caused by chronic atopic dermatitis.
• 02:00
  A 3-Year-Old With Gingival Hemorrhage and Musculoskeletal Pain J Am Med Assoc (JAMA)
  A 3-year-old had spontaneous gingival hemorrhage and bilateral limb weakness with inability to bear weight. He had no preceding oral trauma or recent infection, took no regular medications, and had no recent use of aspirin or nonsteroidal anti-inflammatory drugs; his diet was limited to (...)
• 02:00
  Ponatinib vs Imatinib in Frontline Philadelphia Chromosome–Positive ALL J Am Med Assoc (JAMA)
  This randomized trial assesses the effect of ponatinib vs imatinib combined with low-intensity chemotherapy on disease remission in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia (ALL).
• 02:00
  The “Day of Rest” and Human Efficiency J Am Med Assoc (JAMA)
  The refreshing influence of the weekly recurring “day of rest” on a person subjected to the strenuous routine of a busy life is a feature which he himself can duly appreciate in terms of his “feelings” and “spirits.” If it is desired to demonstrate the need of such relaxation and the benefits (...)
• 02:00
  PhALLCON Soars to New Heights—Faster, Stronger, but Better? J Am Med Assoc (JAMA)
  In this issue of JAMA, Jabbour and colleagues report results from the interim analysis of the PhALLCON randomized trial with ponatinib vs imatinib, combined with reduced-intensity chemotherapy. They found ponatinib to have superior efficacy and a comparable safety profile for frontline (...)
• 02:00
  Service Animals in Health Care Settings J Am Med Assoc (JAMA)
  This JAMA Insights article reviews Americans with Disabilities Act (ADA) rules for patients, visitors, and other members of the public bringing service animals into health care settings.
• 02:00
  Why the Bird Flu Outbreak in Dairy Cows Matters J Am Med Assoc (JAMA)
  This Medical News article discusses the current H5N1 avian influenza outbreak in US dairy cattle and its implications for occupational and public health.
• 02:00
  Patient Information: Poison Ivy, Poison Oak, and Poison Sumac J Am Med Assoc (JAMA)
  This JAMA Patient Page describes allergic skin reactions from contact with poison ivy, poison oak, and poison sumac plants, and how to treat rashes caused by these plants.
• 02:00
  Causal Inference and Effects of Interventions From Observational Studies in Medical Journals J Am Med Assoc (JAMA)
  This Special Communication examines drawing causal inferences about the effects of interventions from observational studies in medical journals.
• 02:00
  College Athlete Deaths by Suicide Have Doubled J Am Med Assoc (JAMA)
  This Medical News story discusses an analysis of deaths by suicide among NCAA athletes over the past 20 years.
• 02:00
  Meaning of Proposed Causal Inference Framework for the JAMA Network J Am Med Assoc (JAMA)
  The Special Communication “Causal Inferences About the Effects of Interventions From Observational Studies in Medical Journals,” published in this issue of JAMA, provides a rationale and framework for considering causal inference from observational studies published by medical journals. Our (...)
• 02:00
  Imaging Approach Tracked Subtle Changes Linked With Mild Brain Injury J Am Med Assoc (JAMA)
  Currently, there are few reliable tools for diagnosing mild traumatic brain injuries or predicting their likely course, which can include poor neuropsychiatric outcomes. But results published in JAMA Network Open show that an advanced form of magnetic resonance imaging picked up changes in the (...)
• 02:00
  Exercise Might Lower Heart Disease Risk in Part By Decreasing Stress in the Brain J Am Med Assoc (JAMA)
  Physical activity might reduce the risk of cardiovascular disease partly by decreasing activity in parts of the brain related to stress, a study in the Journal of the American College of Cardiology suggests. Researchers looked at data from more than 50 300 adults in Massachusetts who completed (...)
• 02:00
  Study: Stigma in Medical Records Tied to Diagnostic Errors J Am Med Assoc (JAMA)
  Patients who were affected by diagnostic errors were more likely to have stigmatizing language in their medical records, according to a new analysis in JAMA Internal Medicine. The cohort study involved more than 2300 hospital admissions during which patients died or were transferred to the (...)
• 02:00
  Permanent Procedures to Prevent Pregnancy in US Jumped After Dobbs J Am Med Assoc (JAMA)
  The number of young people who sought permanent contraception—such as tubal ligations or vasectomies—rose immediately after the US Supreme Court’s decision in Dobbs v Jackson Women’s Health Organization, researchers reported in JAMA Health Forum. The data came from US patients aged 18 to 30 years.
• 02:00
  Deprescribing Program Tied to Reductions in PPI Use in US J Am Med Assoc (JAMA)
  Previous studies have suggested that many people who use proton pump inhibitors (PPIs) might not have a clinical indication for doing so, which is concerning because PPIs have been associated with chronic kidney disease and infection in some observational studies. Now, recent results published (...)
• 02:00
  Five-in-One Meningitis Vaccine Rolls Out J Am Med Assoc (JAMA)
  Nigeria will be the first country in the world to vaccinate residents aged 1 through 29 years with Men5CV, a novel 1-dose vaccine that protects people from 5 major strains of the meningococcus bacteria (Neisseria meningitidis), the World Health Organization (WHO) announced. The news comes amid (...)
• 02:00
  Two-Thirds of Unhoused People Have Mental Health Disorders J Am Med Assoc (JAMA)
  The majority of people who are currently unhoused—67%—have mental health disorders, according to a systematic review and meta-analysis of 85 studies mainly from Canada, Germany, and the US involving more than 48 400 participants. The lifetime prevalence of mental health disorders among people (...)
• 02:00
  Clinicians Underprescribe Newer Antibiotics for Drug-Resistant Disease J Am Med Assoc (JAMA)
  About 42% of patients with infections caused by pathogens that were resistant to all first-line antibiotics received only older antibiotics rather than newer ones more recently approved by the US Food and Drug Administration, a new study found. The results were based on data from 619 US (...)
• 02:00
  National Academies Report: COVID-19 Vaccines Don’t Cause Many Potential Harms J Am Med Assoc (JAMA)
  The COVID-19 vaccines made by Pfizer-BioNTech and Moderna do not cause such conditions as female infertility, myocardial infarction, Bell palsy, or Guillain-Barré syndrome in adults, according to a report by the National Academies of Sciences, Engineering, and Medicine that reviewed evidence (...)
• 02:00
  Heart Failure in African American Individuals, Version 2.0 J Am Med Assoc (JAMA)
  An antecedent body of work established nearly 20 years ago benchmarked the nuanced distinctions of heart failure affecting African American people. Summative statements established a nearly 2-fold higher incidence, earlier onset, greater severity at the time of diagnosis, a more likely (...)
• 02:00
  Cardiovascular Burden of V142I Transthyretin Variant J Am Med Assoc (JAMA)
  This study used data on Black participants in 4 large observational studies to better define the natural history of disease in V142I variant carriers across mid to late life, assess variant modifiers, and estimate cardiovascular burden to the US population.
• 02:00
  Addressing Health Disparities—The Case for Variant Transthyretin Cardiac Amyloidosis Grows Stronger J Am Med Assoc (JAMA)
  There has been a transformational change in understanding heart failure due to transthyretin cardiac amyloidosis (ATTR-CA). Previously considered a rare condition, the widespread adaptation of nuclear imaging to establish the diagnosis has led to the recognition that ATTR-CA is commonly (...)
• 02:00
  Error in the Exclusion of Participants From Analysis in the ACTIV-6 Platform Randomized Clinical Trial J Am Med Assoc (JAMA)
  To the Editor On behalf of my coauthors, I write to explain errors that we identified in the Original Investigation “Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19: A Randomized Clinical Trial,” published online on February 20, (...)
• 02:00
  Errors in Results From Erroneous Exclusion of Participants in Analysis J Am Med Assoc (JAMA)
  The Original Investigation titled “Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19: A Randomized Clinical Trial,” published in the March 21, 2023, issue of JAMA, was corrected to fix an error in which 226 participants were (...)
• 02:00
  Audio Highlights J Am Med Assoc (JAMA)
  Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.
• 02:00
  JAMA J Am Med Assoc (JAMA)

28 May

J Am Med Assoc (JAMA) https://jama.jamanetwork.com/

• 02:00
  Urgent Need for Regulatory Oversight of Human Cellular/Tissue–Based Products J Am Med Assoc (JAMA)
  This Viewpoint discusses the death of a patient caused by unregulated biological products and efforts to encourage federal government oversight of such products.
• 02:00
  My Digital Refuge J Am Med Assoc (JAMA)
  In this narrative medicine essay, a medical ethicist discusses the complexity of juggling the interests of members in online forums dedicated to rare diseases after being blocked upon disclosing her affiliation with a medical school, thus barring her from the support and information she needed (...)
• 02:00
  Varenicline or Nicotine Replacement After Initial Treatment Failure J Am Med Assoc (JAMA)
  This sequential, multiple assignment randomized trial compares treatment strategies and dosages after abstinence from smoking was not achieved after 6 weeks of first-line therapies.
• 02:00
  Patient Information: Strep Throat J Am Med Assoc (JAMA)
  This JAMA Patient Page describes strep throat, its signs and symptoms, diagnosis, treatment, and potential complications.
• 02:00
  Recurrent Gout and Serum Urate—Reply J Am Med Assoc (JAMA)
  In Reply Our recent article quantified the role of serum urate, the central causal biomarker for gout, and found graded associations with recurrent gout flares, including those resulting in hospitalizations (with 100% of these cases associated with serum urate ?5 mg/dL). Regarding the comments (...)
• 02:00
  Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer J Am Med Assoc (JAMA)
  This study examines the potential benefits of aspirin as adjuvant therapy for survivors of early breast cancer.
• 02:00
  At-Home Diagnostics Solutions for Chlamydia and Gonorrhea J Am Med Assoc (JAMA)
  This Viewpoint discusses the US Food and Drug Administration’s authorization of marketing an at-home testing system for chlamydia and gonorrhea as a good first step in boosting access to screening and treatment and in reducing infection rates.
• 02:00
  Outcomes Following Localized Prostate Cancer Treatment J Am Med Assoc (JAMA)
  To the Editor In a recent article that compared adverse outcomes of localized prostate cancer treatment modalities, persistent urinary incontinence after radical prostatectomy was highlighted as a significant difference compared with other therapeutic options. However, the authors overlooked (...)
• 02:00
  Outcomes Following Localized Prostate Cancer Treatment—Reply J Am Med Assoc (JAMA)
  In Reply In response to our recent article, Drs Huang and Ding question the validity of using questionnaires to assess sexual function. While a patient’s responses are subjective (ie, indicating how their function seems to them rather than it being measured more objectively), the use of (...)
• 02:00
  Global Production of Active Pharmaceutical Ingredients for US Generic Drugs Experiencing Shortages J Am Med Assoc (JAMA)
  This study evaluates the characteristics of generic active pharmaceutical ingredients (APIs) used to manufacture drugs with shortages in the US and facilities producing APIs worldwide.
• 02:00
  Outcomes Following Localized Prostate Cancer Treatment J Am Med Assoc (JAMA)
  To the Editor A recent study reported approximately 10-year follow-up data on functional outcomes of patients after treatment for localized prostate cancer, providing essential evidence-based medical evidence for clinical decision-making. We have 2 concerns regarding the data analyses on (...)
• 02:00
  The FDA and Gene Therapy for Duchenne Muscular Dystrophy J Am Med Assoc (JAMA)
  This Viewpoint examines the appropriateness of FDA accelerated approval of novel gene therapies to treat boys with Duchenne muscular dystrophy following clinical trials with surrogate outcomes that did not demonstrate net benefits.
• 02:00
  Aspirin Use and Management of Breast Cancer J Am Med Assoc (JAMA)
  The Alliance trial led by Chen and colleagues and published in this issue of JAMA addresses an important topic in the management of breast cancer: can daily use of 300 mg of aspirin improve invasive disease–free survival among persons with a diagnosis of nonmetastatic, high-risk breast cancer? (...)
• 02:00
  Illness, Isolation, and the Poetry of Illumination J Am Med Assoc (JAMA)
  Commentators on the illness experience, from Broyard to Woolfe, confirm what clinicians frequently observe in patients—to be sick is to feel alone. Whether on a physician’s orders (the tuberculosis sanitorium or COVID-19 social distancing), or due to the lassitude caused by symptoms (...)
• 02:00
  The Women’s Health Initiative Randomized Trials and Clinical Practice J Am Med Assoc (JAMA)
  This review of the Women’s Health Initiative (WHI) summarizes the results of the 4 WHI clinical trials on menopausal hormone therapy, calcium plus vitamin D supplementation, and low-fat diet and their applications to current clinical practice.
• 02:00
  Climate Change and Mental Health J Am Med Assoc (JAMA)
  This JAMA Insights discusses the adverse effects of climate change on mental health and proposes solutions to help mitigate those effects.
• 02:00
  Race and Ethnicity of Reproductive-Age Females Affected by US Abortion Bans J Am Med Assoc (JAMA)
  This study compares the race and ethnicity of reproductive-age females between states that implemented restrictive abortion policies after the Dobbs v Jackson Women’s Health Organization decision and states that did not.
• 02:00
  After the Diagnosis, You Find a Moth J Am Med Assoc (JAMA)
  You have found another one, this time landing on the floor of the living room,
• 02:00
  Incorrect Degree J Am Med Assoc (JAMA)
  In a Letter to the Editor titled “Pharmacotherapy for Alcohol Use Disorder,” published in the March 5, 2024, issue of JAMA, Wenming Shi’s degree was incorrectly listed; it should have been “MSc.” This article was corrected online.
• 02:00
  Table Data Errors J Am Med Assoc (JAMA)
  In the Original Investigation titled “Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial,” published in the April 9, 2024, issue of JAMA, several data errors occurred. The correct risk ratio for the secondary outcome of (...)
• 02:00
  Recurrent Gout and Serum Urate J Am Med Assoc (JAMA)
  To the Editor A recent Review supported use of baseline serum urate level to assess the risk of recurrent gout. A concern raised by the accompanying Editorial pertained to the reliability of a single serum urate measurement.
• 02:00
  Acronymity J Am Med Assoc (JAMA)
  The endemic disease that I call acronymia continues to spread exponentially. New governmental agencies sprout at an alarming rate, and for a long time only their minions know the meaning of the alphabetical nomenclature with which they live. Equally prolific are the trains of capital letters (...)
• 02:00
  Recurrent Gout and Serum Urate J Am Med Assoc (JAMA)
  To the Editor A recent study found that serum urate levels were associated with the risk of subsequent gout flares and hospitalizations for recurrent gout. However, urate-lowering therapy did not significantly alter the association between serum urate levels and the risk of acute gout flares. (...)
• 02:00
  How AI Could Transform Global Mental Health Care J Am Med Assoc (JAMA)
  This Medical News article is an interview with psychiatrist Vikram Patel, chair of the Department of Global Health and Social Medicine at Harvard Medical School.
• 02:00
  “Super Gonorrhea” Has Arrived J Am Med Assoc (JAMA)
  This Medical News article discusses approaches to slow the spread of antimicrobial resistance in Neisseria gonorrhoeae.
• 02:00
  Therapeutic Psilocybin's Adverse Effects Mostly Resolved Within 2 Days J Am Med Assoc (JAMA)
  People who received high or moderate doses of psilocybin for anxiety or depression treatment seemed to manage adverse effects of the drug well, with most issues improving within 1 to 2 days, a recent meta-analysis of 6 studies involving more than 500 participants found. The findings, published (...)
• 02:00
  Young Patients Without Genetic Risk Have Low Chance of Second Breast Cancer J Am Med Assoc (JAMA)
  Previous research has suggested that young people with breast cancer had 2 to 3 times the risk of being diagnosed with secondary breast cancer. But a new study in JAMA Oncology suggests that may not be true for those who do not have a genetic change linked with higher risk of the disease, such (...)
• 02:00
  Swapping Salt for a Substitute May Lower Deaths, Reduce Heart Problems J Am Med Assoc (JAMA)
  Using a salt substitute instead of table salt might lower all-cause and cardiovascular mortality, according to a meta-analysis in Annals of Internal Medicine. The data were based on 16 randomized clinical trials involving more than 35 000 participants, most of whom were from China or Taiwan.
• 02:00
  Encouraging Exercise Through Games, Money Built Long-Term Habits J Am Med Assoc (JAMA)
  People who received financial incentives or gained points for meeting their step goals increased their average daily steps by more than 1500—the equivalent of about three-quarters of a mile—from baseline after 1 year, a recent study published in Circulation found. The randomized clinical trial (...)
• 02:00
  Meta-Analysis: Touch Tied to Improved Mental, Physical Health J Am Med Assoc (JAMA)
  People who received touch interventions, such as massage or gentle stroking for adults and skin-to-skin contact for infants, experienced moderate reductions in pain, depression, and anxiety, according to a meta-analysis of more than 130 studies that involved about 13 000 participants. The (...)
• 02:00
  Prostate Cancer Cases Might Rise to 3 Million Globally by 2040 J Am Med Assoc (JAMA)
  The number of people diagnosed with prostate cancer will more than double worldwide over the next 2 decades, from 1.4 million in 2020 to 2.9 million by 2040, according to findings from a Lancet Commission. More people will also die from the condition, with an estimated 700 000 patients dying (...)
• 02:00
  ?-Blockers After Heart Attacks Might Not Lower Deaths for Some J Am Med Assoc (JAMA)
  Patients typically receive a series of medications, including ?-blockers such as metoprolol and bisoprolol, after experiencing a myocardial infarction, or heart attack. Now, results from a registry-based randomized trial involving more than 5000 participants suggests that some people who’ve (...)
• 02:00
  Oral Drug as Effective as Topical Cream for Male Pattern Baldness J Am Med Assoc (JAMA)
  Oral minoxidil works as well as topical minoxidil 5% for treating people with androgenetic alopecia, also known as male pattern baldness, a double-blind, randomized study found. The results are based on data from 68 men in Brazil aged 18 to 55 years.
• 02:00
  Deaths of Despair Surged Among Black People Over Past Decade J Am Med Assoc (JAMA)
  Guided by findings reported in 2015, researchers have thought that the uptick in midlife deaths of despair—those resulting from suicide, drug overdose, and alcoholic liver disease—disproportionately affected White people. Now, new data published in JAMA Psychiatry illustrate that the decrease (...)
• 02:00
  Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth J Am Med Assoc (JAMA)
  This cross-sectional study compares all-cause and cause-specific mortality trends and rates among youth from different races and ethnicities between 1999 and 2021.
• 02:00
  Youth Parental Death Due to Drug Poisoning and Firearm Violence in the US J Am Med Assoc (JAMA)
  This cross-sectional study uses a demographic projection model and publicly available vital statistics data to estimate the national incidence of parental death due to drugs and firearms overall and by race and ethnicity.
• 02:00
  JAMA J Am Med Assoc (JAMA)
• 02:00
  Injury Prevention Science and Firearm Injury in Pediatric Health J Am Med Assoc (JAMA)
  In this issue of JAMA, Wolf et al found that during the period from 2019 to 2021, the US experienced the greatest increase in all-cause pediatric fatalities (aged 1-19 years) in more than 50 years, with increased mortality disproportionately resulting from preventable injuries. Importantly, (...)
• 02:00
  Audio Highlights J Am Med Assoc (JAMA)
  Listen to the JAMA Editor’s Audio Summary for an overview and discussion of the important articles appearing in this week’s issue of JAMA.