8 articles

19 juin

Nature Reviews Nephrology http://www.nature.com/ncpneph/

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Natural killer cell-mediated innate microvascular rejection - Olivier Thaunat Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 19 June 2024; doi:10.1038/s41581-024-00862-wGraft rejection is traditionally attributed to adaptive immune cells that recognize donor-specific alloantigens, with innate immunity having a secondary role. The finding that recipient natural killer cells (…) (Nature Reviews Nephrology, Published online: 2024-06-19; | doi:10.1038/s41581-024-00862-w)

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Unlocking the benefits of transplantation with kidneys from older donors - Vidya A. Fleetwood, Krista L. Lentine Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 18 June 2024; doi:10.1038/s41581-024-00851-zKidneys from older donors might improve the quality of life and survival of patients with kidney failure, yet these organs are often underutilized. Re-framing discussions of organ acceptance from older (…) (Nature Reviews Nephrology, Published online: 2024-06-18; | doi:10.1038/s41581-024-00851-z)
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Pulmonary hypertension and chronic kidney disease: prevalence, pathophysiology and outcomes - Katarina Zeder, Edward D. Siew, Gabor Kovacs, Evan L. Brittain, Bradley A. Maron Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 18 June 2024; doi:10.1038/s41581-024-00857-7In this Review, the authors discuss potential pathophenotypes of coexisting chronic kidney disease and pulmonary hypertension, discuss the principles of clinical management of patients with chronic kidney (…) (Nature Reviews Nephrology, Published online: 2024-06-18; | doi:10.1038/s41581-024-00857-7)

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Healthy ageing and the kidney — lessons from centenarians - Yasumichi Arai, Motoko Yanagita Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 17 June 2024; doi:10.1038/s41581-024-00860-yCentenarians — who are a putative model of healthy longevity — often have a low risk of cardiovascular disease, despite an age-associated decline in kidney function. An understanding of the molecular and (…) (Nature Reviews Nephrology, Published online: 2024-06-17; | doi:10.1038/s41581-024-00860-y)

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Gene regulatory networks in disease and ageing - Paula Unger Avila, Tsimafei Padvitski, Ana Carolina Leote, He Chen, Julio Saez-Rodriguez, Martin Kann, Andreas Beyer Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 12 June 2024; doi:10.1038/s41581-024-00849-7Perturbations in the regulation of gene expression can contribute to disease- and ageing-associated changes in cell physiology. This review describes how the coordination of gene expression within and (…) (Nature Reviews Nephrology, Published online: 2024-06-12; | doi:10.1038/s41581-024-00849-7)

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Chronic kidney disease in American Indians and Alaska Natives - Vallabh O. Shah, Tassy Parker, Giselle Rodriguez de Sosa, Mark L. Unruh Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 07 June 2024; doi:10.1038/s41581-024-00859-5American Indian and Alaska Native peoples have low life expectancy and a disproportionate disease burden (including of chronic kidney disease), owing to inadequate education, poverty, discrimination and (…) (Nature Reviews Nephrology, Published online: 2024-06-07; | doi:10.1038/s41581-024-00859-5)

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Home monitoring of patients with chronic kidney disease - Sabine H. Josemans, Lucas Lindeboom, Karin G. F. Gerritsen, Fokko P. Wieringa, Jeroen P. Kooman, Joris I. Rotmans Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 04 June 2024; doi:10.1038/s41581-024-00858-6The increasing prevalence of chronic kidney disease (CKD) is placing a growing burden on healthcare systems, which results in considerable economic and environmental challenges. Sustainable CKD care and (…) (Nature Reviews Nephrology, Published online: 2024-06-04; | doi:10.1038/s41581-024-00858-6)

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Cystatin C and the misdiagnosis of CKD in older adults - Andrew D. Rule, Richard J. Glassock Nature Reviews Nephrology

Nature Reviews Nephrology, Published online: 03 June 2024; doi:10.1038/s41581-024-00852-yThe use of cystatin C-inclusive equations will continue to propagate the unnecessary overdiagnosis of chronic kidney disease (CKD) in older people. Cystatin C is less biologically specific for CKD than is (…) (Nature Reviews Nephrology, Published online: 2024-06-03; | doi:10.1038/s41581-024-00852-y)