1 January

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  Can System Solutions Be Scaled to Control High Blood Pressure and Lipids? JAMA Cardiology
  Leaving the broken system the way it is, that’s not a solution.Barack Obama
• 01:00
  Results of a Remotely Delivered Hypertension and Lipid Program in More Than 10 000 Patients JAMA Cardiology
  This cohort study evaluates the efficacy of a remote hypertension and cholesterol management program vs education only among patients with hypertension and/or high cholesterol in a diverse health care network.
• 01:00
  Treatment of Uncomplicated Type B Aortic Dissection JAMA Cardiology
  In a retrospective cohort study of 7105 patients with acute uncomplicated type B aortic dissection (uTBAD) occurring between 2011 and 2018, Weissler et al used inpatient claims data from the US Centers for Medicare & Medicaid Services (CMS) database to examine whether there was any (...)
• 01:00
  Initial TEVAR vs Medical Therapy for Acute Uncomplicated Type B Aortic Dissection JAMA Cardiology
  This cohort study examines the association of initial thoracic endovascular aortic repair (TEVAR) with mortality and morbidity among patients undergoing acute uncomplicated type B aortic dissection.
• 01:00
  Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Preserved Ejection Fraction in the US JAMA Cardiology
  This decision analytical model study quantifies the estimated US population-level impact of reducing heart failure events with sodium-glucose cotransporter-2 inhibitors in left ventricular ejection fraction more than 40%.
• 01:00
  Dapagliflozin and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction JAMA Cardiology
  This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney (...)
• 01:00
  SGLT2i and GLP-1 RA in Patients With Diabetes and Cardiovascular Disease JAMA Cardiology
  This cohort study evaluates the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagonlike peptide-1 receptor agonists (GLP-1 RA) in adults with type 2 diabetes and atherosclerotic cardiovascular disease across a diverse sample of health care systems in the (...)
• 01:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
• 01:00
  Errors in Table and Figure JAMA Cardiology
  The Original Investigation titled “Results of a Remotely Delivered Hypertension and Lipid Program in More Than 10 000 Patients Across a Diverse Health Care Network,” published online November 9, 2022, was corrected to fix the number of participants presented in Table 2 and Figure (...)
• 01:00
  Improving Out-of-Hospital Cardiac Arrest Survival Rates JAMA Cardiology
  Each year, there are nearly 400 000 out-of-hospital cardiac arrest (OHCA) events in the US. The national survival to discharge rate was less than 10% in 2020, and survival varies considerably between communities. Survival rates from OHCA in the US are low since less than 40% receive bystander (...)
• 01:00
  Nudging Clinicians and Patients to Improve Cardiovascular Care JAMA Cardiology
  Since the first randomized clinical trials on computerized clinical decision support (CDS) tools in the 1970s, numerous studies of clinician CDS have demonstrated improvement in clinical processes and, to a lesser extent, clinical outcomes across diverse use cases and settings. The widespread (...)
• 01:00
  Geographic and Urban-Rural Disparities in Cardiac Rehabilitation Eligibility and Use JAMA Cardiology
  This cross-sectional study analyzes county-level eligibility, participation, adherence, and completion rates for cardiac rehabilitation services among Medicare beneficiaries.
• 01:00
  Smartphone Dispatch of Volunteer Responders on Automated External Defibrillators and Out-of-Hospital Cardiac Arrests JAMA Cardiology
  This randomized clinical trial evaluates if bystander automated external defibrillators use could be increased by smartphone-aided dispatch of lay volunteer responders with instructions to collect nearby automated external defibrillator use compared with instructions to go directly to the (...)
• 01:00
  Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing JAMA Cardiology
  This cluster randomized clinical trial in a single health care system investigates the effectiveness of patient and clinician nudges to increase statin prescribing.
• 01:00
  Inequities in Access to Structural Heart Disease Interventions JAMA Cardiology
  This Viewpoint discusses the structural barriers to care that exist for patients of racial and ethnic minoritized and socioeconomically disadvantaged groups and proposes solutions to address the inequities in health care delivery.
• 01:00
  Statin-Associated Muscle Symptoms Among New Statin Users Randomly Assigned to Vitamin D or Placebo JAMA Cardiology
  This study assesses whether vitamin D supplementation prevents statin-associated muscle symptoms and reduces statin discontinuation.
• 01:00
  Ode to Korotkov JAMA Cardiology
  This poem advocates for patient involvement in managing their blood pressure and care decisions.
• 01:00
  Primary Prevention Management of Elevated Lipoprotein(a) JAMA Cardiology
  A male individual in his 40s with a strong family history of atherosclerotic cardiovascular disease including premature cardiovascular events in multiple family members presents to your clinic to establish care for cardiovascular risk stratification. What would you do (...)
• 01:00
  Equitable and Informed Consent in Genetic Studies JAMA Cardiology
  As costs of genetic sequencing have declined and access to testing has become more widespread, genetic epidemiology studies are increasingly conducted to identify new pathogenic variants and understand the prevalence and implications of known pathogenic variants. Ensuring diversity in these (...)
• 01:00
  Knowledge of Genome Sequencing and Trust in Medical Researchers Among Different Racial and Ethnic Groups With DCM JAMA Cardiology
  This study assesses racial and ethnic differences in trust in medical researchers and genome-sequencing knowledge among patients with idiopathic dilated cardiomyopathy.
• 01:00
  COP27 Climate Change Conference JAMA Cardiology
  Wealthy nations must step up support for Africa and vulnerable countries in addressing past, present, and future impacts of climate change.

14 December

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  A Man in His 20s With Gradually Enlarging Mediastinal Mass and Intermittent Hemoptysis JAMA Cardiology
  This case report describes a diagnosis of ruptured coronary artery aneurysm after a patient presentation of chest pain and new-onset intermittent hemoptysis.

1 December

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
• 01:00
  Team-Based Digital Gamification to Improve Cardiovascular Health in Hypertensive Disorders of Pregnancy JAMA Cardiology
  To the Editor We read with great interest the results of Social Ties to Encourage Physical Activity Among Postpartum Mothers (STEP UP Mom). Lewey et al harnessed the principles of behavioral economics by adding team-based digital gamification to daily activity trackers in postpartum women with (...)
• 01:00
  Team-Based Digital Gamification to Improve Cardiovascular Health in Hypertensive Disorders of Pregnancy—Reply JAMA Cardiology
  In Reply We appreciate the thoughtful response from Aryan et al to our article. As the authors highlight, we observed that postpartum individuals with hypertensive disorders of pregnancy (HDP) increased their daily step count by 647 steps when participating in a digital health intervention that (...)
• 01:00
  Effects of Renal Denervation vs Sham in Resistant Hypertension After Medication Escalation JAMA Cardiology
  This prespecified analysis of the Study of the ReCor Medical Paradise System in Clinical Hypertension (RADIANCE-HTN TRIO) randomized clinical trial investigates if the blood pressure–lowering effect of ultrasound renal denervation in patients with resistant hypertension is maintained after the (...)
• 01:00
  My Transcatheter Aortic Valve Replacement JAMA Cardiology
  This essay describes the author’s reflections on the cost of and insurance coverage for a transcatheter aortic valve replacement procedure.
• 01:00
  Concordance Between Patient-Reported Health Data and Electronic Health Data JAMA Cardiology
  This concordance substudy of a comparative effectiveness research trial investigates concordance between patient-reported health data and electronic health data among patients with atherosclerotic cardiovascular disease.
• 01:00
  Association of Race and Ethnicity With Oral Anticoagulation and Outcomes in Atrial Fibrillation JAMA Cardiology
  This cohort study compares oral anticoagulation use at discharge and atrial fibrillation–related outcomes by race and ethnicity in the Get With The Guidelines–Atrial Fibrillation registry.
• 01:00
  When Is a Placebo Not a Placebo JAMA Cardiology
  This Viewpoint discusses the concerns about using mineral oil as a placebo.
• 01:00
  Icosapent Ethyl Supplementation and Cardiovascular Prevention—Implications of Evolving Data JAMA Cardiology
  This Viewpoint discusses the findings of the Reduction of Cardiovascular Events With Icosapent Ethyl Intervention Trial regarding the use of icosapent ethyl in moderate- to high-risk patients with fasting triglyceride levels greater than 135 (...)
• 01:00
  Catheter-Directed Treatment of Submassive Pulmonary Embolism—A Cautious Step Closer? JAMA Cardiology
  Thrombolytic therapy is recommended for patients with pulmonary embolism and hemodynamic compromise, as associated mortality rates are reported to be as high as 50% by 90 days. However, use of thrombolytic therapy for intermediate-risk or submassive pulmonary embolism, defined by right (...)
• 01:00
  Catheter-Directed Thrombolysis vs Anticoagulation in Patients With Acute Intermediate-High–risk Pulmonary Embolism JAMA Cardiology
  This randomized clinical trial investigates the effects of conventional catheter-directed thrombolysis plus anticoagulation in patients with acute intermediate-high risk of pulmonary embolism.
• 01:00
  Association of Serial hsTnT With Subsequent Cardiovascular Events in Patients Stabilized After ACS JAMA Cardiology
  This secondary analysis of a randomized clinical trial evaluates the association of serial changes in high-sensitivity troponin T (hsTnT) and risk of cardiovascular events in stable patients with prior acute coronary syndrome (...)
• 01:00
  Professional Preferences and Perceptions of Cardiology Among Internal Medicine Residents JAMA Cardiology
  This survey study identifies residents’ professional development preferences and cardiology perceptions, in association with specialty choice, and compares the findings with those from a decade prior.
• 01:00
  Food Insecurity, Cardiovascular Disease, and Cardiometabolic Risk Factors Across Race and Ethnicity JAMA Cardiology
  This cross-sectional study examines data from the National Health and Nutrition Examination Survey to assess the prevalence of food insecurity among individuals with cardiovascular disease or cardiometabolic risk factors and analyze any differences across racial and ethnic (...)
• 01:00
  Time to Clinical Benefit of Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction JAMA Cardiology
  This prespecified secondary analysis of the DELIVER trial evaluates the time course of benefits of dapagliflozin on clinically relevant outcomes in patients with HF with mildly reduced or preserved ejection fraction.
• 01:00
  Dapagliflozin and Cause-Specific Mortality in Patients With Heart Failure Across the Spectrum of Ejection Fraction JAMA Cardiology
  This pooled analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF) and Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) trials investigates the effect of dapagliflozin on specific causes of (...)

10 August

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  An Older Woman With a Mobile Right Atrial Mass JAMA Cardiology
  This case report describes an older woman with a diagnosis of right atrial papillary fibroelastoma after presentation and hospitalization for asthenia.

1 August

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
• 02:00
  Characteristics and Outcomes in Isolated Distal vs Proximal Deep Vein Thrombosis JAMA Cardiology
  This cohort study investigates the outcomes and clinical characteristics of patients with isolated distal deep vein thrombosis compared with those with proximal deep vein thrombosis.
• 02:00
  Errors in Text, Table, and Figure JAMA Cardiology
  In the Research Letter titled “Days at Home after Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients,” published Online First on October 20, 2021, and in the January 2022 issue of JAMA Cardiology, Medicare Advantage patients were mistakenly included in the analysis, (...)
• 02:00
  Michael Servetus, Doctor of Medicine JAMA Cardiology
  To the Editor Zargaran should be congratulated for his recent article in JAMA Cardiology reviewing the history of pulmonary circulation and going so far as the ancient Sassanid era to show that some ideas of pulmonary circulation predated in a thousand years the presentation of the lesser (...)
• 02:00
  Explanation for Error in Types of Medicare Patients Included in Aortic Valve Replacement Study JAMA Cardiology
  To the Editor On behalf of my coauthors, I write to report important errors in our Research Letter, “Days at Home after Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients” published Online First on October 20, 2021, and in the January 2022 issue of JAMA Cardiology. (...)
• 02:00
  Michael Servetus, Doctor of Medicine—Reply JAMA Cardiology
  In Reply I read with the great interest the letter of Cobos Gil on my article. Cobos Gil pointed to an important issue concerning Michael Servetus’ views that believed all disciplines are deeply interrelated. He was a theologian as well as a physician. It is an important point in the history of (...)
• 02:00
  Invasive vs Conservative Treatment of Chronic Coronary Disease Across the Spectrum of Kidney Function JAMA Cardiology
  This secondary analysis of a randomized clinical trial evaluates clinical and quality-of-life outcomes following invasive and conservative management of chronic kidney disease.
• 02:00
  Time to Revisit Using 10-Year Risk to Guide Statin Therapy JAMA Cardiology
  Similar to the US, the European Society for Cardiology (ESC) guidelines have long used a 10-year risk score to guide statin therapy in primary prevention. Recently, the risk equation used (Systematic Coronary Risk Evaluation [SCORE]) was updated to SCORE2, estimating risk of nonfatal events (...)
• 02:00
  Replacing Race With Social Determinants of Health in Risk Prediction JAMA Cardiology
  The medical literature is replete with remarkable, even sensationally defined, differences in disease burden and health outcomes as a function of race and ethnicity. Many of those differences are falsely described as biological differences in risk. The described but flawed observations reflect (...)
• 02:00
  Machine Learning and Social Determinants of Health JAMA Cardiology
  Patients admitted with acute heart failure have higher short- and long-term risk of mortality and morbidity with increasing risk for each subsequent hospitalization. In-hospital risk of mortality varies considerably with consistently lower risk among self-described Black patients, partially (...)
• 02:00
  Comparisons of International Guidelines for Statin Eligibility in Primary Prevention of Cardiovascular Disease JAMA Cardiology
  This cohort study examines data from the Copenhagen General Population Study to compare the clinical performance of the 2021 European Society of Cardiology guidelines about statin use with guidelines from the American College of Cardiology/American Heart Association, UK National Institute for (...)
• 02:00
  Machine Learning–Based Models Incorporating SDOH vs Traditional Models for Predicting In-Hospital Mortality for Heart Failure JAMA Cardiology
  This cohort study develops and validates a machine learning–based model incorporating social determinants of health (SDOH) for predicting heart failure mortality.
• 02:00
  Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training JAMA Cardiology
  This randomized clinical trial investigates if starting cardiac rehabilitation exercise training 2 weeks after sternotomy is as effective and safe as starting 6 weeks after sternotomy in cardiac surgery patients.
• 02:00
  Subclinical Leaflet Thrombosis and Anticoagulation After Transcatheter Aortic Valve Replacement JAMA Cardiology
  This narrative review discusses several studies that have investigated the role of oral anticoagulation in patients after transcatheter aortic valve replacement, with a focus on the issue of subclinical leaflet thrombosis.
• 02:00
  Antithrombotic Therapy in Atrial Fibrillation and Coronary Artery Disease JAMA Cardiology
  In the treatment of patients with chronic coronary syndrome, the use of antiplatelets in the form of aspirin is a class 1 indication in the prevention of future thrombotic events. Similarly, oral anticoagulation (OAC) has a class 1 indication for patients with atrial fibrillation (AF) and a (...)
• 02:00
  HIIT vs MCT for Women Undergoing Cardiovascular Rehabilitation JAMA Cardiology
  To the Editor Women continue to be highly underrepresented in cardiovascular rehabilitation (CR) research. Randomized clinical trials (RCTs) have demonstrated the similar and superior efficacy of high-intensity interval training (HIIT) on increasing peak oxygen uptake (peak Vo2) compared with (...)
• 02:00
  HIIT vs MCT for Women Undergoing Cardiovascular Rehabilitation JAMA Cardiology
  To the Editor In a recent article by Khadanga et al, it is reported that among women participating in phase 2 cardiac rehabilitation, undergoing an exercise intervention involving high-intensity interval training (HIIT) and intensive lower extremity resistance training (RT) yields significantly (...)
• 02:00
  HIIT vs MCT for Women Receiving Cardiovascular Rehabilitation—Reply JAMA Cardiology
  In Reply We appreciate the thoughtful commentary from Terada et al and Van Iterson et al to our article. In our study, the moderate continuous training (MCT) group achieved a modest yet significant weight loss, while the high-intensity interval training (HIIT) group remained weight stable. The (...)
• 02:00
  Rivaroxaban Monotherapy vs Combination Therapy on Thrombotic and Bleeding Events in Atrial Fibrillation JAMA Cardiology
  This post hoc secondary analysis of the AFIRE randomized clinical trial investigates if rivaroxaban monotherapy is associated with a lower incidence of cardiovascular/bleeding events than combination anticoagulant and antiplatelet therapy in patients with atrial fibrillation and stable coronary (...)
• 02:00
  Sitting Time and Mortality and Cardiovascular Events in High-Income, Middle-Income, and Low-Income Countries JAMA Cardiology
  This cohort study investigates the association between daily sitting time and mortality and cardiovascular disease in countries of different economic levels.
• 02:00
  A Young Man With Syncope JAMA Cardiology
  A man in his early 20s presented with suspected syncope and shaking with no significant medical history. He denied confusion afterward but did not feel well with nausea, flushing, chest tightness, and a rapid heart rate. What would you do (...)
• 02:00
  External Support for Saphenous Vein Grafts in Coronary Artery Bypass Surgery JAMA Cardiology
  This randomized clinical trial investigates the efficacy and safety of an external saphenous vein graft support device by determining the progression of intimal hyperplasia in patients undergoing a coronary bypass graft procedure.
• 02:00
  Medicine, Writing, and the Limits of Language JAMA Cardiology
  This essay reflects on the author’s experience of 2 worlds—writing and medicine.
• 02:00
  Antiabortion Laws and Implications for Patients With Cardiovascular Disease in Pregnancy JAMA Cardiology
  This Viewpoint discusses the effect of antiabortion legislation on the health of patients with cardiovascular disease in pregnancy.

13 July

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  Incidental Murmur in a Preadolescent Boy JAMA Cardiology
  This case report describes a preadolescent boy with a history of ventriculoperitoneal shunt and an incidental murmur found on physical examination.

1 July

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  Macular Degeneration and CETP Inhibition JAMA Cardiology
  To the Editor We read with interest the recent article associating a harmful age-related macular degeneration (AMD) signal with haplotypes in the cholesteryl ester transfer protein (CETP) gene that underlie lower CETP activity. Genetic association between CETP and AMD was previously reported (...)
• 02:00
  Macular Degeneration and CETP Inhibition—Reply JAMA Cardiology
  In Reply We appreciate the thoughtful comments from Tall et al and welcome the opportunity to reply. Previously, to our knowledge, no studies have directly quantified the balance between the potential long-term benefits and harms associated with genetic cholesteryl ester transfer protein (CETP) (...)
• 02:00
  Health Care Access and Management of Cardiovascular Risk Factors Among Adults With Low Income JAMA Cardiology
  This cross-sectional study evaluates insurance coverage, health care access, and management of cardiovascular risk factors among working-age adults with low income by state Medicaid expansion status and individuals’ insurance (...)
• 02:00
  Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants JAMA Cardiology
  This narrative review evaluates the alignment between clinical practice and randomized clinical trial findings in the use of dose-reduced direct oral anticoagulants.
• 02:00
  Improving the Detection of ST-Segment Elevation Myocardial Infarction in Rural Settings JAMA Cardiology
  Health care disparities occur across a broad range of dimensions but are often viewed through the lens of race, ethnicity, sex, and socioeconomic status. Equally important but less well recognized are disparities related to geographic location. Across many health conditions, including acute (...)
• 02:00
  Treatment Regimen Safety and Efficacy According to Prior Stroke, TIA, or Thromboembolism JAMA Cardiology
  This randomized clinical trial analyzes data comparing treatment regimens according to prior stroke, transient ischemic attack, or thromboembolism to determine the safety and efficacy of apixaban, vitamin K antagonists, and aspirin.
• 02:00
  Management of Acute Coronary Syndromes in Patients in Rural Australia JAMA Cardiology
  This randomized clinical trial seeks to improve outcomes of ST-segment elevation myocardial infarction in rural areas in Australia by reducing missed diagnoses and increasing administration of primary reperfusion therapy.
• 02:00
  Very Elevated High-Density Lipoprotein Cholesterol and Mortality JAMA Cardiology
  A wealth of evidence supports the mechanistic role of high-density lipoprotein cholesterol (HDL-C) in promoting reverse cholesterol transport. HDL-C, therefore, has been postulated to have antiatherogenic properties and termed good cholesterol. Numerous studies have demonstrated higher coronary (...)
• 02:00
  The “Power of Zero” in Younger Patients—A Glass Half Empty or a Glass Half Full? JAMA Cardiology
  To the Editor We read with great interest the study by Mortensen et al on the association of age with the diagnostic value of coronary artery calcium (CAC) score for ruling out coronary stenosis in symptomatic patients undergoing coronary computed tomography angiography for suspected coronary (...)
• 02:00
  The “Power of Zero” in Younger Patients—A Glass Half Empty or a Glass Half Full?—Reply JAMA Cardiology
  In Reply We thank Lopes et al for the thoughtful comments on our recent article on the diagnostic value of a coronary artery calcium (CAC) score of zero to rule out obstructive coronary artery disease (CAD) in patients with stable chest pain. We agree with the points made by Lopes et (...)
• 02:00
  Association Between HDL-C Levels and Adverse Cardiovascular Outcomes JAMA Cardiology
  This cohort study investigates the association between very high high-density lipoprotein cholesterol (HDL-C) level and outcomes in patients with coronary artery disease.
• 02:00
  Genetic Variation and Risk of Hypertrophic Cardiomyopathy JAMA Cardiology
  This cohort study examines data from the UK Biobank and Mass General Brigham Biobank to assess the contribution of rare and common genetic variants to risk of hypertrophic cardiomyopathy in the general population.
• 02:00
  Lipoprotein(a) and its Significance in Cardiovascular Disease JAMA Cardiology
  This narrative review evaluates evidence of an association between elevated lipoprotein(a) levels, atherosclerotic cardiovascular disease, and aortic valve stenosis.
• 02:00
  Genetic Testing for Early-Onset Atrial Fibrillation JAMA Cardiology
  Atrial fibrillation (AF) is the most common arrhythmia, affecting more than 33 million people worldwide. AF is associated with increased risk of stroke and all-cause mortality and often co-occurs with or is caused by heart failure (HF). Because AF can often be asymptomatic and frequently (...)
• 02:00
  Mortality in Early-Onset Atrial Fibrillation and Rare Variants in Cardiomyopathy and Arrhythmia Genes JAMA Cardiology
  This cohort study assesses the association of rare variants of cardiomyopathy and arrhythmia genes with all-cause mortality among patients with early-onset atrial fibrillation.
• 02:00
  Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes JAMA Cardiology
  This genetic association study investigates the association of pathogenic DNA variants implicated in inherited cardiomyopathy with cardiovascular disease outcomes and all-cause mortality.
• 02:00
  Athletes With Cardiovascular Disease and Competitive Sports Eligibility JAMA Cardiology
  This Viewpoint discusses patient centered shared-decision making for athletes with heart disease.
• 02:00
  Trends in Transcatheter vs Surgical Mitral Valve Repair Among Medicare Beneficiaries, 2012 to 2019 JAMA Cardiology
  This cross-sectional study of Medicare data from 2012 to 2019 assesses national trends in the use of mitral transcatheter edge-to-edge repair relative to surgical mitral valve repair.
• 02:00
  USPSTF Report on Aspirin for Primary Prevention JAMA Cardiology
  This Editorial discusses recommendations from the US Preventive Services Task Force on aspirin use to prevent cardiovascular disease and colorectal cancer.
• 02:00
  Passing the Stethoscope JAMA Cardiology
  This essay describes the author’s father, a surgeon, passing the baton on to him as a second-generation pysician.
• 02:00
  Error in SI Conversion Factor JAMA Cardiology
  In the Review titled “Lipoprotein(a) and its Significance in Cardiovascular Disease: A Review,” published on May 18, 2022, there were errors in Table 1 and the Introduction, Evidence Linking Lp(a) to Atherosclerosis, and Modestly Effective Treatments sections. In Table 1, the key findings column (...)
• 02:00
  Error in Figure JAMA Cardiology
  The Review titled “Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review,” published online June 1, 2022, was corrected, as some of the logos in the Figure were misplaced. This article was corrected (...)
• 02:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
• 02:00
  De Novo Hypertensive Disorders of Pregnancy Among Asian and Hispanic Individuals JAMA Cardiology
  This cross-sectional study examines data from the National Center for Health Statistics to determine rates of de novo hypertensive disorders of pregnancy among individuals with a first live birth according to racial and ethnic (...)
• 02:00
  Endurance Exercise and Ascending Thoracic Aortic Aneurysm Resection in Bicuspid Aortic Valve Aortopathy JAMA Cardiology
  This case series study evaluates aortic outcomes in athletes performing endurance exercise or competition after ascending thoracic aortic aneurysm resection with bicuspid aortic valve aortopathy.
• 02:00
  Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest JAMA Cardiology
  This randomized clinical trial investigates the use of emergency coronary angiogram vs delayed coronary angiogram in patients who experience out-of-hospital cardiac arrest without ST-segment elevation.

8 June

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  A Child With Heart Failure and Bumpy Lesions on the Back - Arvind B, Ramakumar V, Ramakrishnan S. JAMA Cardiology
  This case report describes a diagnosis of acute rheumatic fever in a child presenting with fever, dyspnea, and multiple subcutaneous nodules.

1 June

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  Error in Abstract Results Section JAMA Cardiology
  The Brief Report titled “Association of Low-Dose Triple Combination Therapy vs Usual Care With Time at Target Blood Pressure: A Secondary Analysis of the TRIUMPH Randomized Clinical Trial,” published on April 13, 2022, was corrected to fix a typographical error in the Abstract Results section. In (...)
• 02:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
• 02:00
  Treatment of Out-of-Hospital Cardiac Arrest - Lascarrou J, Nichol G. JAMA Cardiology
  Achieving and maintaining good neurologic function and health-related quality of life after discharge are key goals for those who are affected by or care for those with out-of-hospital cardiac arrest (OHCA). Inaccurate early assessment of prognosis and consequent withdrawal of life-sustaining (...)
• 02:00
  Could Neprilysin Be Already Inhibited by BNP in the LIFE Trial? - Vodovar N, Cohen-Solal A, Logeart D. JAMA Cardiology
  To the Editor In the LCZ696 in Hospitalized Advanced Heart Failure (LIFE) trial, the authors reported no benefit of sacubitril/valsartan over valsartan on the primary end points or decrease in plasma N-terminal pro–brain natriuretic peptide (NT-proBNP). Data from Prospective Comparison of ARNI (...)
• 02:00
  Could Neprilysin Be Already Inhibited by BNP in the LIFE Trial?—Reply - Mann DL, Hernandez AF, Braunwald E. JAMA Cardiology
  In Reply In the LCZ696 in Hospitalized Advanced Heart Failure (LIFE) trial, we did not observe a statistically significant difference between sacubitril/valsartan and valsartan with respect to the time-averaged proportional change in the area under the curve (AUC) for N-terminal pro–brain (...)
• 02:00
  Trends in 10-Year Outcomes Among Medicare Beneficiaries Who Survived an Acute Myocardial Infarction - Wang Y, Leifheit EC, Krumholz HM. JAMA Cardiology
  This cohort study evaluates trends in 10-year all-cause mortality and hospitalization for recurrent acute myocardial infarction by demographic subgroups and examines the association between recurrence and mortality.
• 02:00
  Long-term Survival After Out-of-Hospital Cardiac Arrest - Amacher SA, Bohren C, Blatter R, et al. JAMA Cardiology
  This meta-analysis of patients with out-of-hospital cardiac arrest assesses the long-term survival rate in those who survive the initial hospital stay.
• 02:00
  Association of COVID-19 Vaccination With Outcomes in Heart Transplant Recipients - Peters LL, Raymer DS, Pal JD, et al. JAMA Cardiology
  This case-control study assesses data from a single center about the safety and effectiveness of COVID-19 vaccination among patients who received an orthotopic heart transplant.
• 02:00
  Who Is at Risk for Heart Failure? - Yancy CW, Khan SS. JAMA Cardiology
  The availability of evidence-based medical interventions to prevent the onset of signs and symptoms of heart failure (HF) affords a unique opportunity to attenuate the risk for a disease with substantial morbidity and mortality. Targeting prevention of HF is an apt goal. Yet determining those (...)
• 02:00
  Sex and Race Differences in NT-proBNP Concentration and Absolute Risk of Heart Failure in the Community - Myhre PL, Claggett B, Yu B, et al. JAMA Cardiology
  This cohort study aims to determine whether physiologic determinants of N-terminal pro–B-type natriuretic peptide concentrations account for sex and race differences and aims to more uniformly predict heart failure risk.
• 02:00
  Current Landscape and Future Directions of Coronary Revascularization in Patients With Heart Failure - Ahmad Y, Lansky AJ, Velazquez EJ. JAMA Cardiology
  This Viewpoint discusses current options and future directions for coronary artery revascularization for the management of coronary artery disease in patients with heart failure.
• 02:00
  Communicating the Benefits of Vaccination in Light of Potential Risks - Navar A, Bonow RO. JAMA Cardiology
  Since the initial case reports of myocarditis following COVID-19 vaccination, several population-based studies have demonstrated an increased risk of myocarditis following vaccination, including nationwide studies in England and Israel. In this issue of JAMA Cardiology, Karlstad and colleagues (...)
• 02:00
  No Diagnostic Concerns With Cardiovascular Magnetic Resonance Imaging in Patients With Breast Cancer and Breast Implants - Manisty C, Barac A, Lenihan D. JAMA Cardiology
  To the Editor We welcome the Viewpoint from Oren et al highlighting the importance of ensuring high-quality cardiovascular (CV) imaging for patients living with (or survivors of) breast cancer with breast implants. Patients commonly require functional CV imaging to establish CV safety during or (...)
• 02:00
  No Diagnostic Concerns With Cardiovascular Magnetic Resonance Imaging in Patients With Breast Cancer and Breast Implants—Reply - Oren O, Blankstein R, Bhatt DL. JAMA Cardiology
  In Reply We thank Manisty et al for the opportunity to further reinforce the strengths and potential pitfalls of contemporary cardiovascular imaging in women who have been diagnosed with breast cancer and who underwent breast reconstruction. Cardiac magnetic resonance imaging (CMR) represents (...)
• 02:00
  Gamification Intervention to Improve Physical Activity in Postpartum Individuals With Hypertensive Disorders of Pregnancy - Lewey J, Murphy S, Zhang D, et al. JAMA Cardiology
  This randomized clinical trial determines whether a digital health intervention can improve physical activity in postpartum individuals with hypertensive disorders of pregnancy.
• 02:00
  SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents - Karlstad Ø, Hovi P, Husby A, et al. JAMA Cardiology
  This cohort study conducted using nationwide registers assesses the risks of myocarditis and pericarditis after SARS-CoV-2 messenger RNA vaccinations in a combined population of 23.1 million individuals across Denmark, Finland, Norway, and (...)
• 02:00
  Association of Low-Dose Triple Combination Therapy vs Usual Care With Time at Target Blood Pressure - Gnanenthiran SR, Wang N, Di Tanna G, et al. JAMA Cardiology
  This post hoc analysis of a randomized clinical trial evaluates the association of time at target blood pressure with low-dose triple combination antihypertensive therapy vs usual care.
• 02:00
  Meaningful Evidence for Anticoagulation in the Gray (Elder) Zone - Alexander KP. JAMA Cardiology
  As more people are living longer lives, the number of older adults with atrial fibrillation (AF), a common age-associated condition, will increase. Advanced age coincides with changes in kidney and hepatic function, body mass and composition, and use of concomitant therapies with the potential (...)
• 02:00
  Edoxaban in Older Patients With Atrial Fibrillation - Kuroda M, Tamiya E, Nose T, et al. JAMA Cardiology
  This randomized clinical trial investigates the effect of 15-mg edoxaban in patients aged 80 years and older who are not candidates for standard-dose oral anticoagulants owing to bleeding risk.
• 02:00
  My Grandfather’s Blueprint - Love K. JAMA Cardiology
  This essay describes the author’s experience building a canoe during medical school and residency.

11 May

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  JAMA Cardiology Peer Reviewers in 2021 JAMA Cardiology

1 May

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
• 02:00
  Lipoprotein(a), Menopausal Hormone Therapy, and Risk of Coronary Heart Disease in Postmenopausal Individuals - Honigberg MC, Trinder M, Natarajan P. JAMA Cardiology
  This observational study examines whether hormone therapy use modifies the association of lipoprotein(a) with coronary heart disease.
• 02:00
  Validating Deep Learning to Distinguish Takotsubo Syndrome From Acute Myocardial Infarction - Wehbe RM, Thomas JD. JAMA Cardiology
  Artificial intelligence, particularly deep learning (DL), is poised to transform the field of cardiovascular imaging. While still a relatively young discipline, there has been an explosion of research in DL for cardiovascular imaging as investigators seek to build systems designed to segment (...)
• 02:00
  In Memoriam: Jeremiah Stamler, MD, 1919-2022 - Greenland P, Lloyd-Jones DM. JAMA Cardiology
  Jeremiah Stamler, MD, was a pioneer and champion of preventive cardiology, a fighter for civil liberties, a prodigious researcher, teacher, mentor, colleague, and friend to thousands.
• 02:00
  Septal Reduction Strategies in Hypertrophic Cardiomyopathy - Bataiosu D, Rakowski H. JAMA Cardiology
  Dynamic left ventricular outflow (LVOT) obstruction is present at rest or with provocation in up to two-thirds of patients with hypertrophic cardiomyopathy (HCM) and can cause disabling symptoms and an increased risk of sudden death. LVOT obstruction is caused by rapid left ventricular ejection (...)
• 02:00
  Artificial Intelligence in Differentiating Takotsubo Syndrome From Myocardial Infarction - Laumer F, Di Vece D, Cammann VL, et al. JAMA Cardiology
  This cohort study assesses the utility of a fully automated and interpretable machine learning–based framework in differentiating takotsubo syndrome from acute myocardial infarction using raw echocardiographic imaging data.
• 02:00
  Outcomes of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia Treated With ?-Blockers - Mazzanti A, Kukavica D, Trancuccio A, et al. JAMA Cardiology
  This cohort study investigates the long-term outcomes of patients with RYR2 catecholaminergic polymorphic ventricular tachycardia treated with ?-blockers only and the cost to benefit ratio of implantable cardioverter defibrillator.
• 02:00
  Percutaneous Intramyocardial Septal Radiofrequency Ablation in Drug-Refractory Hypertrophic Obstructive Cardiomyopathy - Zhou M, Ta S, Hahn RT, et al. JAMA Cardiology
  This cohort study assesses the safety and medium-term outcomes of percutaneous intramyocardial septal radiofrequency ablation in a large patient cohort with drug-refractory hypertrophic obstructive cardiomyopathy.
• 02:00
  What We Know and Don’t Know About Renal Denervation to Lower Blood Pressure - Chau KH, Azizi M, Kirtane AJ. JAMA Cardiology
  This Viewpoint discusses renal denervation as a potential alternative therapy to medication in patients whose hypertension is medication resistant.
• 02:00
  Myocardial Fibrosis, Stroke Volume by CMR, and Outcome After Valve Replacement in Patients With Severe AS - Thornton GD, Musa TA, Rigolli M, et al. JAMA Cardiology
  This cohort study assesses the association of left ventricular indexed stroke volume as measured by cardiac magnetic resonance (CMR) with myocardial remodeling and survival among patients with severe aortic stenosis (AS) after valve (...)
• 02:00
  TET2 -Driven Clonal Hematopoiesis and Response to Canakinumab - Svensson EC, Madar A, Campbell CD, et al. JAMA Cardiology
  This genomic substudy of a randomized clinical trial assesses whether patients with clonal hematopoiesis of intermediate potential have greater cardiovascular event reduction in response to canakinumab.
• 02:00
  JAMA Cardiology —The Year in Review, 2021 - Bonow RO. JAMA Cardiology
  After the unprecedented volume of manuscript submissions in 2020 addressing the COVID-19 pandemic and its cardiovascular complications—with more than 900 COVID-19–related manuscripts submitted to JAMA Cardiology from March through December that year—life for journal editors slowly returned to (...)
• 02:00
  Behind the Hospital Curtain - Peters R. JAMA Cardiology
  This essay describes a physician’s experience becoming a patient for the first time and the valuable knowledge this experience imparted.
• 02:00
  Improving Enrollment of Underrepresented Racial and Ethnic Populations in Heart Failure Trials - DeFilippis EM, Echols M, Adamson PB, et al. JAMA Cardiology
  This Special Communication outlines strategies for heart failure clinical trials to promote enrollment of participants from underrepresented racial and ethnic minority groups.
• 02:00
  Insights and Opportunities in STEMI Care in China - Jneid H. JAMA Cardiology
  Cardiovascular diseases are the most common noncommunicable diseases worldwide, causing nearly 18 million deaths or 32% of global deaths in 2019. Of those, 85% were attributable to myocardial infarction and stroke events, and more than 75% occurred in low-income and middle-income countries. The (...)
• 02:00
  Performance of Guideline-Recommended Strategies for Hospitalized Patients With STEMI in China - Hao Y, Zhao D, Liu J, et al. JAMA Cardiology
  This quality improvement study analyzes data from a nationwide registry in China to investigate how care is provided in relation to guideline recommendations for patients hospitalized with ST-segment elevation myocardial infarction.
• 02:00
  When an Aortic Bioprosthesis Fails in a Low-risk Patient - Raschpichler M, Thiele H, Borger MA. JAMA Cardiology
  This Viewpoint discusses the need for randomized clinical trial data to determine the optimal treatment strategy for patients with failed aortic bioprostheses.
• 02:00
  Exercise and Resistant Hypertension—Is Exercise Enough? - Blumenthal JA, Sherwood A, Hinderliter AL. JAMA Cardiology
  To the Editor We read with interest the report by Lopes et al describing the results of the Exercise Training in the Treatment of Resistant Hypertension (EnRicH) trial of 53 patients with resistant hypertension, which demonstrated that a 12-week exercise program reduced 24-hour ambulatory (...)
• 02:00
  Exercise and Resistant Hypertension—Is Exercise Enough?—Reply - Ribeiro F, Pescatello LS, Alves AJ. JAMA Cardiology
  In Reply We thank Blumenthal and colleagues for their interest and comments on the Exercise Training in the Treatment of Resistant Hypertension (EnRicH) trial. We agree with Blumenthal et al that there has been little research studying the effects of exercise alone or combined with lifestyle (...)
• 02:00
  Age-Adjusted Survival Extrapolations—Results May Differ From Those Generated by the Weibull Model - Messori A, Mengato D, Chiumente M. JAMA Cardiology
  To the Editor In analyzing a clinical trial, extrapolating survival curves beyond the length of the follow-up is an option that, for many years, has attracted the interest of researchers. For example, when 2 treatments are being compared, this extrapolation provides a useful estimate of the (...)
• 02:00
  Age-Adjusted Survival Extrapolations—Results May Differ From Those Generated by the Weibull Model—Reply - Jhund PS, Docherty KF, McMurray JV. JAMA Cardiology
  In Reply Although Messori and colleagues estimated a smaller increase in event-free survival than we did, the Weibull-based approach they used they has several limitations. They tried to extract data from published figures, which is not as reliable as using original data, and small differences (...)
• 02:00
  Factors Affecting Yield of Genetic Testing of Sudden Deaths in Young Individuals - Cheung CC, Tseng ZH. JAMA Cardiology
  To the Editor In a recent issue of JAMA Cardiology, Webster et al presented the genomic analysis of their cohort of 103 decedents, surviving family members, and matched controls referred from 60 county medical examiner and coroner’s offices in 24 states over 4 years. Using whole-genome (...)
• 02:00
  Factors Affecting Yield of Genetic Testing of Sudden Deaths in Young Individuals—Reply - Webster G, George AL, Jr, McNally EM. JAMA Cardiology
  In Reply We appreciate the thoughtful perspective on our recent work in JAMA Cardiology. In particular, Cheung and Tseng are interested in understanding the true prevalence of sudden cardiac death. They point out that in a research setting, phenotype-based inclusion criteria may cause an (...)
• 02:00
  Potential Role and Limitations of eGFR Slope Assessment in Cardiovascular Trials - Khan M, Bakris GL, Shahid I, et al. JAMA Cardiology
  This narrative review explores the use of eGFR slope in clinical trials, its strengths and limitations, and the implications of adopting it as a viable outcome in cardiovascular outcome trials.
• 02:00
  Remote Cardiac Monitoring in Patients With Heart Failure - Kennel PJ, Rosenblum H, Axsom KM, et al. JAMA Cardiology
  This narrative review explores current remote cardiac monitoring technologies available to cardiologists and the most recent developments in the field, allowing a look into the future of heart failure management.

13 April

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  Bizarre Wide-Complex Tachycardia in a Man in His 60s With Severe Chest Pain - Chuang Y, Tsai C. JAMA Cardiology
  This case report describes a diagnosis of myocardial infarction in a man in his 60s who presented with chest pain and exhibited bizarre wide-complex tachycardia on electrocardiogram.

1 April

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 02:00
  Error in Figure Caption JAMA Cardiology
  The Clinical Challenge titled “A Young Woman With Viral Myocarditis,” published on February 23, 2022, was corrected to update the legend for the figure. The legend now reads “Transesophageal echocardiogram after low-flow alarm on peripheral ventricular assist device console. A, 2-Dimensional (...)
• 02:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology is the definitive journal for (...)
• 02:00
  Characteristics and Outcomes of Type 2 Myocardial Infarction - Coscia T, Nestelberger T, Boeddinghaus J, et al. JAMA Cardiology
  This cohort study explores the characteristics and outcomes of patients with type 2 myocardial infarction compared with those with type 1 myocardial infarction.
• 02:00
  Prasugrel Dose De-escalation Therapy After in Complex PCI in Patients With ACS - Hwang D, Lim Y, Park K, et al. JAMA Cardiology
  This post hoc analysis investigates whether the benefits of prasugrel dose de-escalation therapy are maintained in the complex percutaneous coronary intervention subgroup.
• 02:00
  Clopidogrel Monotherapy After 1 to 2 Months of DAPT vs 12 Months of DAPT in Acute Coronary Syndrome - Watanabe H, Morimoto T, Natsuaki M, et al. JAMA Cardiology
  This randomized clinical trial evaluates whether 1 to 2 months of dual antiplatelet therapy (DAPT) followed by clopidogrel monotherapy is noninferior to 12 months of DAPT with aspirin and clopidogrel for patients with acute coronary (...)
• 02:00
  Fibrillar Collagen Variants in Spontaneous Coronary Artery Dissection - Zekavat S, Chou EL, Zekavat M, et al. JAMA Cardiology
  This case-control study assesses which genes contribute to the development of spontaneous coronary artery dissection.
• 02:00
  Finding Pulmonary Arterial Hypertension - Maron BA, Humbert M. JAMA Cardiology
  This Viewpoint discusses the importance of finding early pulmonary arterial hypertension to achieve disease mitigation.
• 02:00
  A Young Woman With Viral Myocarditis - Rao R, Torabi AJ, Saleem K. JAMA Cardiology
  A woman in her mid-20s presented with cardiogenic shock and required extracorporeal membrane oxygenation with peripheral ventricular assist device implantation. After decannulation, the patient developed hematuria and pulmonary edema and low-flow alarms sounded on her device console. What would (...)
• 02:00
  PVC Burden and Arrhythmic Risk in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy - Gasperetti A, Cappelletto C, Carrick R, et al. JAMA Cardiology
  This cohort study describes changes in premature ventricular contraction burden over time and assesses whether a changing burden on follow-up Holter monitoring is associated with subsequent arrhythmic events in patients with arrhythmogenic right ventricular (...)
• 02:00
  High-Throughput Precision Phenotyping of LV Hypertrophy With Cardiovascular Deep Learning - Duffy G, Cheng PP, Yuan N, et al. JAMA Cardiology
  This cohort study assesses the accuracy of a deep learning algorithm in measuring left ventricular dimensions and identifying patients with increased wall thickness who may benefit from additional screening for hypertrophic cardiomyopathy and cardiac (...)
• 02:00
  Effect of Transcutaneous Magnetic Stimulation in Patients With Ventricular Tachycardia Storm - Markman TM, Pothineni NK, Zghaib T, et al. JAMA Cardiology
  This randomized clinical trial evaluates the safety and efficacy of transcutaneous magnetic stimulation of the left stellate ganglion for patients with ventricular tachycardia storm.
• 02:00
  To Occlude or Not to Occlude the Left Atrial Appendage in Women - Ahuja T, Kiefer NJ, Manmadhan A. JAMA Cardiology
  To the Editor The National Cardiovascular Data Registry left atrial appendage occlusion (LAAO) cohort study by Darden and colleagues provides imperative data for clinicians to consider regarding LAAO in women. The Watchman device (Boston Scientific) has been used to occlude the LAA, as an (...)
• 02:00
  To Occlude or Not to Occlude the Left Atrial Appendage in Women—Reply - Darden D, Freeman JV, Hsu JC. JAMA Cardiology
  In Reply We thank Ahuja and colleagues for their comments regarding our recent sex-specific analysis of procedural outcomes among patients undergoing left atrial appendage occlusion (LAAO) using the National Cardiovascular Data Registry (NCDR). We reported that women were at higher risk of (...)
• 02:00
  N-Terminal Pro-Brain Natriuretic Peptide Measurements in Patients With Aortic Stenosis - Hadziselimovic E, Greve AM, Sajadieh A, et al. JAMA Cardiology
  This substudy of a randomized clinical trial examines the association between annual measurement of N-terminal pro-brain natriuretic peptide levels and outcomes in patients with aortic stenosis.
• 02:00
  Temporal Associations Between Immunization With the COVID-19 mRNA Vaccines and Myocarditis - Keith JS, McDonough MM, Dimitrakoff JD. JAMA Cardiology
  To the Editor? JAMA Cardiology recently initiated an ongoing discussion regarding the prevalence and significance of postvaccination myocarditis (PVM) in adolescents and the role that physicians and policy makers should play in communicating the risks of vaccination or nonvaccination to (...)
• 02:00
  Association of Titin Variations With Late-Onset Dilated Cardiomyopathy - Cannatà A, Merlo M, Dal Ferro M, et al. JAMA Cardiology
  This cohort study investigated the genetic background and the natural history of a large international cohort of dilated cardiomyopathy presenting in individuals older than 60 years to assess the importance of genetic testing in those (...)
• 02:00
  Hypertriglyceridemia in the MESA Study - Hansel B, Roussel R, Giral P. JAMA Cardiology
  To the Editor In a cross-sectional study assessing the association between risk-enhancing factors of cardiovascular disease (CVD) and coronary artery calcium (CAC) scoring, Patel et al concluded that high triglyceride levels (?175 mg/dL [to convert to millimoles per liter, multiply by 0.0113]) (...)
• 02:00
  Hypertriglyceridemia in the MESA Study—Reply - Patel J, Blumenthal RS, Al Rifai M. JAMA Cardiology
  In Reply We appreciate the thoughtful Letter to the Editor and welcome the opportunity to reply. Our analysis sought to follow novel, guideline-driven recommendations for the use of available risk-enhancing factors and coronary artery calcium (CAC) to guide the initiation of statin therapy. (...)
• 02:00
  Prevalence and Trends of Coronary Heart Disease in the United States - Lee Y, Fang J, Schieb L, et al. JAMA Cardiology
  This survey study examines prevalence of coronary heart disease and the trend from 2011 to 2018 using self-reported data from the Behavioral Risk Factor Surveillance System.
• 02:00
  Recommendations on Treatment Effects in the Presence of Terminal Competing Risks - McCaw ZR, Claggett B, Tian L, et al. JAMA Cardiology
  This narrative review discusses 3 commonly used methods for analyzing dependent competing risks data.

9 March

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  A Man in His 60s With Pneumonia and Multiple Reintubation Attempts - Tsai M, Lai C, Chang L. JAMA Cardiology
  This case report describes a diagnosis of pneumopericardium in a man in his 60s after multiple reintubation attempts owing to respiratory failure from pneumonia.

1 March

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology is the definitive journal for (...)
• 01:00
  Echocardiography for the Diagnosis of CTRCD in Women With Early-Stage Breast Cancer - Esmaeilzadeh M, Urzua Fresno CM, Somerset E, et al. JAMA Cardiology
  This cohort study evaluates the accuracy of echocardiography and serum biomarkers in diagnosing cancer therapy–related cardiac dysfunction.
• 01:00
  Noninferiority Margins in Clinical Trials—A Moving Target? - Wang L, Torguson R, Farb A. JAMA Cardiology
  Noninferiority trials, often referred to as the “as good as” trials, are the most common current pivotal study designs used in the evaluation of investigational coronary stents submitted for regulatory review. In coronary revascularization device trials, predominately for drug-eluting stents (...)
• 01:00
  Consequences of Inaccurate Assumptions in Coronary Stent Noninferiority Trials - Simonato M, Ben-Yehuda O, Vincent F, et al. JAMA Cardiology
  This systematic review and meta-analysis assesses the impact of imprecise event rate estimations on interpretation of peer-reviewed randomized clinical trials.
• 01:00
  Updated USPSTF Guidelines for Screening for Atrial Fibrillation - Passman R, Freedman B. JAMA Cardiology
  This Editorial discusses atrial fibrillation screening recommendations from the US Preventive Services Task Force.
• 01:00
  Wide Complex QRS During Sotalol Administration - Rogers AJ, Wang PJ, Badhwar N. JAMA Cardiology
  A man in his 40s was seen in clinic for a long history of palpitations. He had a history of cardiac arrest after receiving adenosine for sustained supraventricular tachycardia and tachycardia-induced cardiomyopathy. What would you do (...)
• 01:00
  Leadless Pacing—Uncertainties Remain About Safety and Efficacy - Ngo L, Denman R, Ranasinghe I. JAMA Cardiology
  To the Editor We read with interest the recent study by Piccini et al on the comparative safety of the Micra leadless pacemakers (LP) and single-chamber transvenous pacemakers (TVP) among Medicare beneficiaries. While postmarket safety data on this innovative technology are welcomed, there are (...)
• 01:00
  Leadless Pacing—Uncertainties Remain About Safety and Efficacy—Reply - El-Chami MF, Piccini JP, Bockstedt L. JAMA Cardiology
  In Reply We thank Ngo et al for their interest in our article. Our study reported the rate of acute complications, device complications at 6 months, and need for system revision at 6 months among patients implanted with a leadless VVI vs transvenous VVI pacemaker using Medicare claims (...)
• 01:00
  Association of Plaque Location and Vessel Geometry With Future ACS-Causing Culprit Lesions - Han D, Lin A, Kuronuma K, et al. JAMA Cardiology
  This cohort study assesses the association of adverse geometric characteristics of coronary lesions with location and vessel geometry on coronary computed tomographic angiography.
• 01:00
  Center-Level Variation in Transplant Rates Following the Heart Allocation Policy Change - Tran Z, Hernandez R, Madrigal J, et al. JAMA Cardiology
  This cohort study evaluates center-level transplant rates following the recent allocation policy change for heart transplant.
• 01:00
  Association of NT-proBNP in Early Pregnancy With Development of Hypertensive Disorders During and After Pregnancy - Hauspurg A, Marsh DJ, McNeil RB, et al. JAMA Cardiology
  This cohort study investigates whether higher concentrations of N-terminal pro–brain natriuretic peptide (NT-proBNP) in early pregnancy are associated with hypertensive disorders of pregnancy and hypertension 2 to 7 years post (...)
• 01:00
  Association of Sexual Intercourse With Sudden Cardiac Death in Young Individuals in the United Kingdom - Finocchiaro G, Westaby J, Behr ER, et al. JAMA Cardiology
  This case series assesses the cardiac conditions associated with sudden deaths during or immediately after sexual intercourse.
• 01:00
  Cardiac Fluorodeoxyglucose–PET/MRI Assessment of Myocardial Injury in COVID-19 - Hanneman K, Houbois C, Schoffel A, et al. JAMA Cardiology
  This cohort study examines myocardial metabolic changes early after recovery from COVID-19 using fluorodeoxyglucose–positron emission tomography (PET) and shows an association of these changes with abnormalities in cardiac magnetic resonance imaging (MRI)–based function and tissue (...)
• 01:00
  Factors Underlying Sex-Based Disparities in Cardiovascular Care in Adults With Self-reported Premature ASCVD - Jain V, Al Rifai M, Turpin R, et al. JAMA Cardiology
  This cohort study evaluates the association of sex with physical and mental health domains as well as health care access–related factors among adults with self-reported premature atherosclerotic cardiovascular disease.
• 01:00
  Sex Difference in Bleeding Risk With P2Y12 Inhibitor Agents After Percutaneous Coronary Intervention - Chen P, Lee C, Liu P. JAMA Cardiology
  To the Editor The sex-specific subgroup analysis of the TWILIGHT study published by Vogel et al offers important insight in that it suggests the higher bleeding rates seen in female patients compared with male patients receiving ticagrelor treatment after percutaneous coronary intervention may (...)
• 01:00
  Sex Difference in Bleeding Risk With P2Y12 Inhibitor Agents After Percutaneous Coronary Intervention—Reply - Vogel B, Huber K, Mehran R. JAMA Cardiology
  In Reply We greatly appreciate the acknowledgment of our analysis on sex differences in the TWILIGHT trial in a Letter to the Editor by Chen and colleagues. The authors of the letter point out to our statement that in the TWILIGHT trial, the incremental bleeding risk associated with female sex (...)
• 01:00
  The Right Time for a Heart Valve Replacement - Hutchens P. JAMA Cardiology
  This essay describes the author’s 80-year heart valve journey and the advances that have been made over that time.
• 01:00
  Cardiovascular Risk and Events in Black and White Individuals - Zhang L, Olalere D, Mayrhofer T, et al. JAMA Cardiology
  This cohort study compares the risk factors and noninvasive testing outcomes of Black and White persons with stable chest pain.
• 01:00
  Association of Complement and MAPK Activation With SARS-CoV-2 Myocardial Inflammation - Weckbach LT, Schweizer L, Kraechan A, et al. JAMA Cardiology
  This case series uses histologic, transcriptomic, and proteomic profiling to investigate the inflammatory cardiac phenotype among patients with SARS-CoV-2 infection compared with patients with noninflammatory cardiomyopathy and virus-associated and immune-mediated (...)
• 01:00
  ApoB vs LDL-Cholesterol and Non-HDL-C as the Primary Measure of ApoB Lipoprotein-Related Risk - Sniderman AD, Navar A, Thanassoulis G. JAMA Cardiology
  In 1979, Avogaro et al reported that apolipoprotein B (apoB) was a more accurate marker of the risk of a myocardial infarction than total cholesterol. In 1980, Sniderman et al reported that low-density lipoprotein (LDL) apoB was a more accurate marker of the risk of angiographic coronary (...)
• 01:00
  ApoB-Containing Lipoproteins and Risk of MI in Individuals With and Without Atherosclerosis - Marston NA, Giugliano RP, Melloni GM, et al. JAMA Cardiology
  This cohort study evaluates whether common measures of cholesterol concentration, triglyceride concentration, or their ratio are associated with cardiovascular risk beyond the number of apolipoprotein B–containing lipoproteins.
• 01:00
  Mitigation of CVD Risk After Adverse Pregnancy Outcomes - Jowell AR, Sarma AA, Gulati M, et al. JAMA Cardiology
  This narrative review assesses the evidence for targeted postpartum risk-reducing interventions and identifies optimal care and areas of future investigation among women with adverse pregnancy outcomes.

9 February

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  A 49-Year-Old Woman With Progressive Dyspnea - Dai H, Zhang W, Guang X. JAMA Cardiology
  This case report describes a woman with heart failure and low-voltage electrocardiogram who had periorbital ecchymosis and apical sparing.

1 February

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

• 01:00
  Treating Severe Hypercholesterolemia—If Not Now, When? - Stone NJ. JAMA Cardiology
  Clinical guideline evidence matters. Recent 2018 American Heart Association/American College of Cardiology/Multisociety guidelines present strong evidence to support maximally tolerated statin therapy as a first step in patients aged 20 to 75 years with primary severe elevations of low-density (...)
• 01:00
  Management of Severe and Moderate Hypercholesterolemia in Young Women and Men - Newton SL, Hoffmann AP, Yu Z, et al. JAMA Cardiology
  This study uses clinical registry data to assess achievement of low-density lipoprotein cholesterol reduction and lipid-lowering therapy prescribing patterns among adults aged 20 to 39 years with moderate to severe hypercholesterolemia.
• 01:00
  Metabolomic Analysis of Coronary Heart Disease in an African American Cohort - Cruz DE, Tahir UA, Hu J, et al. JAMA Cardiology
  This cohort study examines metabolites associated with incident coronary heart disease and coronary artery calcium among African American participants in the Jackson Heart Study and seeks to replicate coronary heart disease findings among multiethnic participants in the Women’s Health (...)
• 01:00
  Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation - Marcus GM, Modrow M, Schmid CH, et al. JAMA Cardiology
  This randomized clinical trial tests the hypothesis that n-of-1 trials of self-selected atrial fibrillation triggers would enhance atrial fibrillation–related quality of life.
• 01:00
  Race Bias in Transcatheter Aortic Valve Replacement Are We Sure? - Yancy CW, Kirtane A. JAMA Cardiology
  Despite breakthrough science and innovative procedures, cardiovascular disease is rife with evidence-based racial disparities. Adopting quality initiatives, raising awareness, and inciting discussions about unconscious bias are recommended steps intended to narrow cardiovascular disease (...)
• 01:00
  Racial, Ethnic, and Socioeconomic Disparities in Access to Transcatheter Aortic Valve Replacement in Metro Areas - Nathan AS, Yang L, Yang N, et al. JAMA Cardiology
  This national cross-sectional analysis examines the association between zip code–level racial, ethnic, and socioeconomic composition and rates of transcatheter aortic valve replacement among Medicare patients living within large metropolitan areas in the (...)
• 01:00
  Outcomes Associated With Catheter Ablation of VT in Patients With Cardiac Sarcoidosis - Siontis KC, Santangeli P, Muser D, et al. JAMA Cardiology
  This cohort study investigates outcomes associated with ventricular tachycardia ablation in patients with cardiac sarcoidosis.
• 01:00
  Evaluation of Quality of Care for Veterans With Recent-Onset HFrEF - Sandhu AT, Kohsaka S, Turakhia MP, et al. JAMA Cardiology
  This cohort study evaluates the use of guideline-directed medical therapy and implantable cardioverter-defibrillator as well as mortality rates over a 6-year period among patients with heart failure with reduced ejection fraction in the US Department of Veterans Affairs health care (...)
• 01:00
  Addressing Imaging Pitfalls to Reduce Cardiovascular Disease Misdiagnosis in Patients With Breast Cancer Following Reconstruction - Oren O, Blankstein R, Bhatt DL. JAMA Cardiology
  This Viewpoint discusses the challenges of cardiovascular imaging in patients with breast cancer after reconstruction.
• 01:00
  Coronary Artery Calcium Testing in the Prevention of Atherosclerotic Cardiovascular Disease - Greenland P, Lloyd-Jones DM. JAMA Cardiology
  This narrative review provides an overview of coronary artery calcium testing as a tool for risk assessment in the prevention of atherosclerotic cardiovascular disease.
• 01:00
  Role of Income-Lifting Social Programs in Reducing Years of Life Lost to Myocardial Infarction and Sudden Death - Senter E, Vrooman H, Shartle K. JAMA Cardiology
  To the Editor We appreciate the work of Berman and colleagues, who investigated the association between socioeconomic disadvantage and mortality after a myocardial infarction (MI). The authors found that among people who had an MI before age 50 years, patients who lived in the most (...)
• 01:00
  Role of Income-Lifting Social Programs in Reducing Years of Life Lost to Myocardial Infarction and Sudden Death—Reply - Berman AN, DeFilippis EM, Blankstein R. JAMA Cardiology
  In Reply We appreciate the letter by Senter and colleagues highlighting the important implications of socioeconomic deprivation on clinical outcomes. As our research highlighted, neighborhood-level socioeconomic disadvantage is associated with increasing all-cause and cardiovascular mortality (...)
• 01:00
  Error in the First Paragraph JAMA Cardiology
  In the Editorial titled, “The Potential and Pitfalls of Coronary Artery Calcium Scoring,” which published online October 27, 2021, the following sentence is incorrect: “Beyond this recommendation, however, some investigators have called for even more aggressive de-risking of patients with a CAC (...)
• 01:00
  Treatment Intensification, Missed Visits, and Racial and Ethnic Disparities in Hypertension Control - Commodore-Mensah Y, Himmelfarb C. JAMA Cardiology
  Uncontrolled hypertension is a public health priority, with only 1 in 5 US adults with hypertension achieving blood pressure (BP) control. Furthermore, persistent racial and ethnic disparities in hypertension diagnosis and control are well documented. Compared with other racial and ethnic (...)
• 01:00
  Inclusion of Smoking Data in Cardiovascular Disease Risk Estimation - Duncan MS, Greevy RA, Tindle HA, et al. JAMA Cardiology
  This cohort study evaluates the predictive utility of adding former smoking status, pack-years smoked, and years since quitting to the American College of Cardiology/American Heart Association 2013 pooled cohort equations for more accurate atherosclerotic cardiovascular disease risk (...)
• 01:00
  Association of Health Care Processes With Racial or Ethnic Disparities in Blood Pressure Control - Fontil V, Pacca L, Bellows BK, et al. JAMA Cardiology
  This cohort study assesses whether and to what extent differences in treatment intensification, scheduled follow-up interval, and missed visits are associated with racial and ethnic disparities in blood pressure control among adults with (...)
• 01:00
  Optimizing Training Response for Women in Cardiac Rehabilitation - Khadanga S, Savage PD, Pecha A, et al. JAMA Cardiology
  This randomized clinical trial evaluates the effect of high-intensity interval training and intensive lower extremity resistance training compared with standard moderate intensity continuous training on peak oxygen uptake among women in cardiac (...)
• 01:00
  Health Status Improvement and Costs - Heidenreich PA. JAMA Cardiology
  As the number and price of novel medical treatments accelerate, there is heightened interest in determining their value. A price typically reflects a manufacturer’s estimate of society’s willingness to pay for their product. Treatments that improve survival appropriately command higher prices, (...)
• 01:00
  Prevalence and Disease Spectrum of Extracoronary Arterial Abnormalities in Coronary Artery Dissection - Persu A, Lopez-Sublet M, Al-Hussaini A, et al. JAMA Cardiology
  This case series examines the prevalence of fibromuscular dysplasia and other extracoronary events in patients who develop spontaneous coronary artery dissection.
• 01:00
  Economic Outcomes of Rehabilitation Therapy in Older Patients With Acute Heart Failure - Chew DS, Li Y, Zeitouni M, et al. JAMA Cardiology
  This secondary analysis of a randomized clinical trial’s economic outcomes reports the cumulative medical resource use and costs during the 6-month follow-up period for patients randomized to an intervention or control condition for acute decompensated heart (...)
• 01:00
  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology publishes exceptional original research, state-of-the-art reviews, and informative opinions that advance the science and practice of cardiology, enhance cardiovascular health, and inform health care policy. JAMA Cardiology is the definitive journal for (...)
• 01:00
  The Inglorious Art - Olivotto I. JAMA Cardiology
  This essay discusses how the wounding and treatment of Aeneas in the Aeneid can be interpreted as a metaphor for basic science advancing medical practice.
• 01:00
  The Gig Economy Worker—A New Social Determinant of Health? - Rodriguez F, Sarraju A, Turakhia MP. JAMA Cardiology
  This Viewpoint discusses how the rapid rise of the gig economy has resulted in a fast-growing workforce segment with unique health vulnerabilities.
• 01:00
  A Man With Left Ventricular Hypertrophy - Hiraki N, Tanaka TD, Yoshimura M. JAMA Cardiology
  A man in his 40s with a 20-year history of bilateral sensorineural hearing loss was referred for evaluation of left ventricular hypertrophy detected by echocardiography. On physical examination, he was 154 cm tall and weighed 38 kg and neurological examination showed mild cognitive impairment, (...)
• 01:00
  Lifestyle Modification Is Appropriate as Primary Prevention - Conte HA, Janket S, Diamandis EP. JAMA Cardiology
  To do nothing is sometimes a good remedy.Hippocrates
• 01:00
  Lifestyle Modification Is Appropriate as Primary Prevention—Reply - Bhattacharya R, Natarajan P. JAMA Cardiology
  In Reply We thank Conte et al for their interest in our article. The intersection of clonal hematopoiesis (CH), diet, inflammation, and infectious risk indeed merits discussion and consideration. Conte et al highlight the potential that diet and CH may be contributing to enhanced inflammation, (...)
• 01:00
  Hereditary Transthyretin Amyloid Cardiomyopathy - Youmans QR, Shah SJ, Khan SS. JAMA Cardiology
  This Patient Page describes the causes, symptoms, diagnosis, genetic testing, and treatment of amyloidogenic transthyretin.