1 March

JAMA Cardiology https://jamanetwork.com/journals/jamacardiology

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  JAMA Cardiology JAMA Cardiology
  Mission Statement:? JAMA Cardiology is positioned at the nexus of clinical investigation, actionable clinical science, and clinical practice, with emphasis on traditional cardiovascular medicine, evolving cardiovascular science, and evidence-based health policy. Health equity, especially when (...)
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  Association of Long-term Change in N-Terminal Pro–B-Type Natriuretic Peptide With Incident Heart Failure and Death JAMA Cardiology
  This cohort study assesses the association between change in N-terminal pro–B-type natriuretic peptide with risk for incident heart failure and death.
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  Association of Tafamidis With Health Status in Patients With Transthyretin Cardiac Amyloidosis JAMA Cardiology
  This post hoc analysis of a randomized clinical trial examines data for patients according to the New York Heart Association class of their heart failure symptoms at baseline to evaluate the health status benefit of tafamidis vs (...)
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  A Man in His 30s With Splenic Infarct and Stroke JAMA Cardiology
  This case report describes a diagnosis of quadricuspid aortic valve in a man in his 30s with a history of splenic infarct who presented with right-sided ischemic stroke.
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  Rare Protein-Truncating DNA Variants in APOB or PCSK9 , LDL Cholesterol Level, and Risk of Coronary Heart Disease JAMA Cardiology
  This genetic association study evaluates the association of protein-truncating variants in APOB and PCSK9 with low-density lipoprotein (LDL) cholesterol levels and coronary heart disease.
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  Effect of Personalized Accelerated Pacing on Quality of Life, Physical Activity, and Atrial Fibrillation in HFpEF JAMA Cardiology
  This randomized clinical trial assesses the effects of a moderately accelerated personalized backup heart rate compared with 60 bpm in patients with heart failure with preserved ejection fraction (HFpEF) who have preexisting pacemaker systems that limit pacemaker-mediated (...)
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  Prediction Accuracy of Models for the Time of a Cardiovascular Event—Moving Beyond C Statistic JAMA Cardiology
  This narrative review discusses the model selection and evaluation process with respect to prediction accuracy when the outcome of interest is timing of a cardiovascular event.
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  Defining Rural in Rural-Urban Differences in Myocardial Infarction Management JAMA Cardiology
  To the Editor In a recent multicenter investigation, Hillerson et al highlighted important disparities in ST-segment elevation myocardial infarction management between those residing in rural vs urban settings. The lack of observed differences in outcome measures among these settings, despite (...)
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  Defining Rural in Rural-Urban Differences in Myocardial Infarction Management—Reply JAMA Cardiology
  In Reply We appreciate Cohen’s interest in our article. In our work comparing the process of care and the hospital outcomes of urban vs rural patients with ST-elevation myocardial infarction (STEMI), we used the data elements collected in the National Cardiovascular Data Registry Chest Pain–MI (...)
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  Association of Rurality With Risk of Heart Failure JAMA Cardiology
  This cohort study analyzes data for participants from the Southern Community Cohort Study to determine whether rurality is associated with increased risk of heart failure and whether rurality-associated risk varies by race and (...)
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  Association of Plasma HDL-C Level With Risk of Fractures in Healthy Older Adults JAMA Cardiology
  This cohort study performs a post hoc analysis of data for US and Australian participants in the Aspirin in Reducing Events in the Elderly (ASPREE) clinical trial to determine the association between level of high-density lipoprotein cholesterol and increased fracture risk in healthy older (...)
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  Higher High-Density Lipoprotein Cholesterol—Good Omen, Bad Omen, or Not an Omen at All JAMA Cardiology
  In the study by Hussain et al, published in this issue of JAMA Cardiology, the authors used the Aspirin in Reducing Events in the Elderly (ASPREE) trial in a post hoc analysis to conduct an observational study assessing the associations between high-density lipoprotein cholesterol (HDL-C) at (...)
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  Effects of Mavacamten on Measures of Cardiopulmonary Exercise Testing Beyond Peak Oxygen Consumption JAMA Cardiology
  This study examines the effect of mavacamten on exercise physiology using cardiopulmonary exercise testing.
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  Jumpstarting the Journey to Transesophageal Echocardiogram Mastery JAMA Cardiology
  The SIMULATOR study was a French trial performed in 42 university centers where fellows who were inexperienced in transesophageal echocardiogram (TEE) were randomized to simulation-based vs traditional teaching on TEE knowledge and skills. Authors measured theoretical and practical scores 3 (...)
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  Estimation of Out-of-Pocket Costs for Guideline-Directed Medical Therapy for Heart Failure JAMA Cardiology
  This cross-sectional study estimates out-of-pocket costs of heart failure with reduced ejection fraction medication regimens in Medicare Part D under current law and the Inflation Reduction Act.
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  Effectiveness of Simulation-Based Training on Transesophageal Echocardiography Learning JAMA Cardiology
  This study attempts to assess the effectiveness of simulation-based vs traditional teaching of transesophageal echocardiography knowledge and skills of cardiology fellows.
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  Management Challenges in Patients Younger Than 65 Years With Severe Aortic Valve Disease JAMA Cardiology
  This narrative review describes options for the management of severe aortic valve disease in adults younger than 65 years and offers a framework for shared decision-making relative to different sets of complications and long-term (...)
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  Wide Complex Tachycardia in a Middle-aged Man JAMA Cardiology
  A man in his mid-50s with a medical history of nonspecific T-wave abnormalities on electrocardiogram reported new-onset chest discomfort, diaphoresis, and shortness of breath that woke him from sleep. Emergency medical services found him to be in a wide complex tachycardia. What would you do (...)