500 posts

17 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:28
A Longitudinal Study of Acculturation in Context and Cardiovascular Health and Their Effects on Cognition Among Older Latino Adults - Melissa Lamar, Mayra L. Estrella , Ana W. Capuano , Sue Leurgans , Debra A. Fleischman , Lisa L. Barnes , Brittney S. Lange?Maia , David A. Bennett , and David X. Marquez 1 Rush Alzheimer’s Disease Center Rush University Medical Center Chicago IL 2 Department of Psychiatry and Behavioral Sciences Rush University Medical Center Chicago IL 3 Department of Epidemiology, Human Genetics and Environmental Sciences University of Texas Health Science Center at Houston School of Public Health Brownsville TX 4 Department of Neurological Sciences Rush University Medical Center Chicago IL 5 Department (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundWe previously outlined the importance of considering acculturation within the context of older Latino adults' lived experience (ie, acculturation in context) to better capture contributors to cognitive aging. We now examine (...) (Journal of the American Heart Association)
03:00
Sex Disparities in Diagnostic Evaluation and Revascularization in Patients With Acute Myocardial Infarction—A 15?Year Nationwide Study - Muddasir Ashraf, M. Fuad Jan , Tanvir. K Bajwa , Ryan Carnahan , Viviana Zlochiver , and Suhail Q. Allaqaband 1 Aurora Cardiovascular and Thoracic Services, Aurora Sinai/Aurora St. Luke’s Medical Centers, Advocate Aurora Health University of Wisconsin School of Medicine and Public Health Milwaukee WI 2 The University of Iowa College of Public Health Iowa City IA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundAlthough sex disparities in the diagnostic evaluation and revascularization of patients with acute myocardial infarction are well documented, no study has evaluated longitudinal trends in these disparities.Methods and (...) (Journal of the American Heart Association)
03:00
Epiphenomenon or Prognostically Relevant Interventional Target? A Novel Proportionality Framework for Severe Tricuspid Regurgitation - Vera Fortmeier, Mark Lachmann , Matthias Unterhuber , Lukas Stolz , Mohammad Kassar , Laurin Ochs , Muhammed Gerçek , Anne R. Schöber , Thomas J. Stocker , Hazem Omran , Maria I. Körber , Amelie Hesse , Kai Peter Friedrichs , Shinsuke Yuasa , Tanja K. Rudolph , Michael Joner , Roman Pfister , Stephan Baldus , Karl?Ludwig Laugwitz , Fabien Praz , Stephan Windecker , Jörg Hausleiter , Philipp Lurz , and Volker Rudolph 1 Department of General and Interventional Cardiology, Heart and Diabetes Center North Rhine?Westphalia Ruhr University Bochum Bad Oeynhausen Germany 2 First Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundTricuspid regurgitation (TR) frequently develops in patients with long?standing pulmonary hypertension, and both pathologies are associated with increased morbidity and mortality. This study aimed to improve prognostic (...) (Journal of the American Heart Association)
02:59
Bone Morphogenetic Protein 10—A Novel Biomarker to Predict Adverse Outcomes in Patients With Atrial Fibrillation - Elisa Hennings, Steffen Blum , Stefanie Aeschbacher , Michael Coslovsky , Sven Knecht , Ceylan Eken , Mirko Lischer , Rebecca E. Paladini , Philipp Krisai , Tobias Reichlin , Nicolas Rodondi , Jürg H. Beer , Peter Ammann , Giulio Conte , Maria Luisa De Perna , Richard Kobza , Manuel R. Blum , Matthias Bossard , Peter Kastner , André Ziegler , Christian Müller , Leo H. Bonati , Otmar Pfister , Christine S. Zuern , David Conen , Michael Kühne , Stefan Osswald , and 1 Cardiovascular Research Institute Basel University Hospital Basel, University of Basel Basel Switzerland 2 Cardiology University (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundPatients with atrial fibrillation (AF) face an increased risk of death and major adverse cardiovascular events (MACE). We aimed to assess the predictive value of the novel atrial?specific biomarker BMP10 (bone morphogenetic (...) (Journal of the American Heart Association)
02:59
Left Atrial Remodeling Following ST?Segment–Elevation Myocardial Infarction Correlates With Infarct Size and Age Older Than 70 Years - Adrien Pascaud, Antonildes Assunção , Gabriel Garcia , Eloi Vacher , Serge Willoteaux , Fabrice Prunier , Alain Furber , and Loïc Bière 1 Institut Mitovasc, UMR CNRS 6015?INSERMU1083, University of Angers Angers France 2 Department of Cardiology University Hospital of Angers Angers France 3 Heart Institute, InCor University of Sao Paulo Medical School Sao Paulo Brazil 4 Department of Radiology, University Hospital of Angers Angers France J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundFollowing myocardial infarction, left ventricular remodeling (LVR) is associated with heart failure and cardiac death. At the same time, left atrial (LA) remodeling (LAR) is an essential part of the outcome of a wide spectrum (...) (Journal of the American Heart Association)
02:59
Duration of Heightened Risk of Acute Ischemic Stroke After Hospitalization for Acute Systolic Heart Failure - Devin J. Burke, Tehniyat Baig , Parag Goyal , Hooman Kamel , Richa Sharma , Neal S. Parikh , Stephen A. McCullough , Cenai Zhang , and Alexander E. Merkler 1 Division of Neurocritical Care Weill Cornell Medicine New York NY USA 2 Weill Cornell Medicine – Qatar Doha Qatar 3 Clinical and Translational Neuroscience Unit Feil Family Brain and Mind Research Institute New York NY USA 4 Department of Neurology Weill Cornell Medicine New York NY USA 5 Department of Medicine Weill Cornell Medicine New York NY USA 6 Department of Neurology Yale School of Medicine New Haven CT (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe duration and magnitude of increased stroke risk after a hospitalization for acute systolic heart failure (HF) remains uncertain.Methods and ResultsThe authors performed a retrospective cohort study using claims (2008–2018) (...) (Journal of the American Heart Association)
02:58
Growth Differentiation Factor 15 and Risk of Bleeding Events: The Atherosclerosis Risk in Communities Study - Lena Mathews, Xiao Hu , Ning Ding , Junichi Ishigami , Mahmoud Al Rifai , Ron C. Hoogeveen , Josef Coresh , Christie M. Ballantyne , Elizabeth Selvin , and Kunihiro Matsushita 1 Department of Epidemiology, Welch Center Department of Epidemiology, Prevention and Clinical Research Johns Hopkins Bloomberg School of Public Health Baltimore MD 2 Division of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins School of Medicine Baltimore MD 3 Houston Methodist DeBakey Heart & Vascular Center Houston TX 4 Department of Medicine, Section of Cardiovascular (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundGDF15 (growth differentiation factor 15) is a potent predictor of bleeding in people with cardiovascular disease. However, whether GDF15 is associated with bleeding in individuals without a history of cardiovascular disease is (...) (Journal of the American Heart Association)
02:58
Childhood Dyslipidemia and Carotid Atherosclerotic Plaque in Adulthood: The Cardiovascular Risk in Young Finns Study - Juhani S. Koskinen, Ville Kytö , Markus Juonala , Jorma S. A. Viikari , Jaakko Nevalainen , Mika Kähönen , Terho Lehtimäki , Nina Hutri?Kähönen , Tomi P. Laitinen , Päivi Tossavainen , Eero Jokinen , Costan G. Magnussen , and Olli T. Raitakari 1 Research Centre of Applied and Preventive Cardiovascular Medicine University of Turku Turku Finland 2 Centre for Population Health Research University of Turku and Turku University Hospital Turku Finland 3 Division of Medicine Turku University Hospital Turku Finland 4 Department of Medicine Satakunta Central Hospital Pori Finland 5 Heart Centre Turku (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundChildhood exposure to dyslipidemia is associated with adult atherosclerosis, but it is unclear whether the long?term risk associated with dyslipidemia is attenuated on its resolution by adulthood. We aimed to address this (...) (Journal of the American Heart Association)
02:56
?1 and ?2C?Adrenergic Receptor Polymorphisms Are Associated With Lower Incident Ventricular Fibrillation in Patients With ST?Segment–Elevation Myocardial Infarction - Bachir Lakkiss, and Marwan M. Refaat 1 Division of Cardiology, Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
03:03
Human Resistin Induces Cardiac Dysfunction in Pulmonary Hypertension - Qing Lin, Santosh Kumar , Udeshika Kariyawasam , Xiaomei Yang , Wei Yang , John T. Skinner , Wei Dong Gao , and Roger A. Johns 1 Department of Anesthesiology and Critical Care Medicine Johns Hopkins University School of Medicine Baltimore MD 2 Department of Anesthesiology Qilu Hospital, Cheeloo College of Medicine, Shandong University Jinan China 3 Department of Cardiovascular Medicine Xiangya Hospital, Central South University Changsha China J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundCardiac failure is the primary cause of death in most patients with pulmonary arterial hypertension (PH). As pleiotropic cytokines, human resistin (Hresistin) and its rodent homolog, resistin?like molecule ?, are mechanistically (...) (Journal of the American Heart Association)
03:02
Novel Measures of Arterial Hemodynamics and Wave Reflections Associated With Clinical Outcomes in Patients With Heart Failure - Rebecca S. Steinberg, Eisha Udeshi , Neal Dickert , Arshed Quyyumi , Julio A. Chirinos , and Alanna A. Morris 1 Division of Cardiology Emory University Atlanta GA 2 Division of Cardiology University of Pennsylvania Philadelphia PA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundArterial stiffness and earlier wave reflections can increase afterload and impair cardiovascular function. Most prior studies have been performed in patients with preserved left ventricular function. We describe novel measures (...) (Journal of the American Heart Association)

16 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:19
Social Determinants of Cardiovascular Risk, Subclinical Cardiovascular Disease, and Cardiovascular Events - Isaac Acquah, Kobina Hagan , Zulqarnain Javed , Mohamad B. Taha , Javier Valero?Elizondo , Nwabunie Nwana , Tamer Yahya , Garima Sharma , Martha Gulati , Aziz Hammoud , Michael D. Shapiro , Ron Blankstein , Michael J. Blaha , Miguel Cainzos?Achirica , and Khurram Nasir 1 Center for Outcomes Research Houston Methodist Houston TX 2 Division of Health Disparities and Equity Research Center for Outcomes Research, Houston Methodist Houston TX 3 Division of Cardiovascular Prevention and Wellness Houston Methodist DeBakey Heart and Vascular Center Houston TX 4 Ciccarone Center for the Prevention (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundAlthough there is research on the impact of social determinants of health (SDOHs) on cardiovascular health, most existing evidence is based on individual SDOH components. We evaluated the impact of cumulative SDOH burden on (...) (Journal of the American Heart Association)
13:19
Impact of Neuroeffector Adrenergic Receptor Polymorphisms on Incident Ventricular Fibrillation During Acute Myocardial Ischemia - Philippe Chevalier, Pascal Roy , Francis Bessière , Elodie Morel , Bénédicte Ankou , Gina Morgan , Indrani Halder , Barry London , Wayne A. Minobe , Dobromir Slavov , Antoine Delinière , Thomas Bochaton , Franck Paganelli , Nathalie Lesavre , Clément Boiteux , Jacques Mansourati , Philippe Maury , Gaël Clerici , Pierre François Winum , Sophia P. Huebler , Ian A. Carroll , and Michael R. Bristow 1 Rhythmology Department Hospital Louis Pradel Lyon France 2 Université Claude Bernard Lyon 1 Université de Lyon Lyon France 3 Hospices Civils de Lyon, Services Biostatistiques Lyon France 4 Division of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundCardiac adrenergic receptor gene polymorphisms have the potential to influence risk of developing ventricular fibrillation (VF) during ST?segment?elevation myocardial infarction, but no previous study has comprehensively (...) (Journal of the American Heart Association)
13:19
Prognostic Value of Transthoracic Echocardiography in Children With Pulmonary Arterial Hypertension - Astrid E. Lammers, Jan Marek , Gerhard?Paul Diller , Sheila G. Haworth , and Shahin Moledina 1 Paediatric Cardiology and the UK Pulmonary Hypertension Service for Children Great Ormond Street Hospital for Children London United Kingdom 2 Paediatric Cardiology and Specialist Clinic for Paediatric Pulmonary Hypertension Muenster University Hospital Muenster Germany 3 Adult Congenital Heart Disease Unit Muenster University Hospital Muenster Germany 4 Institute of Cardiovascular Sciences University College London United (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundTransthoracic echocardiography is part of the regular follow?up protocol at most pediatric pulmonary arterial hypertension (PAH) centers. We aimed to develop a comprehensive and simple echocardiographic risk stratification for (...) (Journal of the American Heart Association)

14 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

06:17
Remote Cardiovascular Hypertension Program Enhanced Blood Pressure Control During the COVID?19 Pandemic - Simin Gharib Lee, Alexander J. Blood , Christopher P. Cannon , William J. Gordon , Hunter Nichols , David Zelle , Benjamin M. Scirica , and Naomi D. L. Fisher 1 Division of Cardiology, Department of Medicine Brigham and Women’s Hospital and Harvard Medical School Boston MA 2 Harvard Medical School Boston MA 3 Division of General Internal Medicine and Primary Care Brigham and Women’s Hospital Boston MA 4 Department of Pharmacy Services Boston MA 5 Division of Endocrinology, Diabetes and Hypertension Brigham and Women’s Hospital Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe COVID?19 pandemic disrupted traditional health care; one fallout was a drastic decrease in blood pressure (BP) assessment. We analyzed the pandemic's impact on our existing remote hypertension management program's (...) (Journal of the American Heart Association)

9 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:48
Serum Pro?N?Cadherin Is a Marker of Subclinical Heart Failure in the General Population - Paul Durham Ferrell, Kristianne Michelle Oristian , Ishaan Puranam , and Salvatore Vincent Pizzo 1 Department of Pathology Duke University School of Medicine Durham NC 2 Department of Radiation Oncology Duke University School of Medicine Durham NC 3 Department of Biomedical Engineering Duke University Pratt School of Engineering Durham NC J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundWe recently reported aberrant processing and localization of the precursor PNC (pro?N?cadherin) protein in failing heart tissues and detected elevated PNC products in the plasma of patients with heart failure. We hypothesize (...) (Journal of the American Heart Association)
12:48
Variability in Nonvitamin K Oral Anticoagulant Dose Eligibility and Adjustment According to Renal Formulae and Clinical Outcomes in Patients With Atrial Fibrillation With and Without Chronic Kidney Disease: Insights From ORBIT?AF II - Ren Jie Robert Yao, DaJuanicia N. Holmes , Jason G. Andrade , Adeera Levin , Jonathan P. Piccini , and Christopher B. Fordyce 1 Division of Cardiology, Department of Medicine University of British Columbia Canada 2 Duke Clinical Research Institute Durham NC 3 Center for Cardiovascular Innovation Vancouver Canada 4 Montreal Heart Institute, Department of Medicine Université de Montréal Canada 5 Division of Nephrology, Department of Medicine University of British Columbia Vancouver British Columbia Canada 6 Centre for Health Evaluation and Outcome Sciences Vancouver British Columbia (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundNonvitamin K oral anticoagulants require dose adjustment based on kidney function.The most common estimate of kidney function employed in clinical practice is estimated glomerular filtration rate (eGFR); however, product (...) (Journal of the American Heart Association)
12:48
Single?Antiplatelet Treatment After Coronary Angioplasty With Drug?Coated Balloon - Bernardo Cortese, and Patrick W. Serruys 1 Cardiovascular Research Center, Fondazione Ricerca e Innovazione Cardiovascolare Milan Italy 2 DCB Academy Milan Italy 3 Department of Cardiology National University of Ireland, Galway (NUIG) Galway Ireland 4 CORRIB Research Centre for Advanced Imaging and Core laboratory, NHLI Imperial College London London UK J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:48
Role of Polymorphonuclear Myeloid?Derived Suppressor Cells and Neutrophils in Ischemic Stroke - Haomin Yan, Tomohiro Kawano , Hideaki Kanki , Kumiko Nishiyama , Munehisa Shimamura , Hideki Mochizuki , and Tsutomu Sasaki 1 Department of Neurology, Graduate School of Medicine Osaka University Osaka Japan 2 Department of Neurotherapeutics, Graduate School of Medicine Osaka University Osaka Japan 3 Department of Health Development and Medicine Osaka University Graduate School of Medicine Osaka Japan J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundImmune cells play a vital role in the pathology of ischemic stroke. Neutrophils and polymorphonuclear myeloid?derived suppressor cells share a similar phenotype and have attracted increasing attention in immune regulation (...) (Journal of the American Heart Association)
12:47
Association Between Risk Factors in Childhood and Sex Differences in Prevalence of Carotid Artery Plaques and Intima?Media Thickness in Mid?Adulthood in the Childhood Determinants of Adult Health Study - Mohammad Shah, Marie?Jeanne Buscot , Jing Tian , Hoang T. Phan , Brooklyn J. Fraser , Thomas H. Marwick , Terence Dwyer , Alison Venn , and Seana Gall 1 Menzies Institute for Medical Research University of Tasmania Hobart Tasmania Australia 2 School of Clinical Sciences at Monash Health Monash University Clayton Victoria Australia 3 Baker Heart and Diabetes Institute Melbourne Victoria Australia 4 Cardiology Department, Western Health Melbourne Australia 5 Departments of Cardiometabolic Health and Medicine University of Melbourne Melbourne Australia 6 Department of Public Health (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe origins of sex differences in cardiovascular diseases are not well understood. We examined the contribution of childhood risk factors to sex differences in adult carotid artery plaques and intima?media thickness (carotid (...) (Journal of the American Heart Association)
12:47
Correction to: Myocardial Cytoskeletal Adaptations in Advanced Kidney Disease J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:47
Correction to: Lectin?Like Oxidized Low?Density Lipoprotein Receptor 1 Inhibition in Type 2 Diabetes: Phase 1 Results J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:47
Right Ventricular Dysfunction in Pulmonary Hypertension: Is Resistin a Promising Target? - Sarah?Eve Lemay, Yann Grobs , and Olivier Boucherat 1 Pulmonary Hypertension Research Group Centre de Recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Québec Québec City Québec Canada 2 Department of Medicine Université Laval Québec City Québec Canada J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:46
Correction to: Racial and Ethnic Disparities in Financial Barriers Among Overweight and Obese Adults Eligible for Semaglutide in the United States J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:46
Correction to: Effect of Heart Rate on 1?Year Outcome for Patients With Acute Ischemic Stroke J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:44
Heart Failure: Insights From the Arterial Waves - Bernhard Hametner, Thomas Weber , and Siegfried Wassertheurer 1 Center for Health & Bioresources AIT Austrian Institute of Technology Vienna Austria 2 Cardiology Department, Klinikum Wels?Grieskirchen Wels Austria J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:42
Diabetes Induces Cardiac Fibroblast Activation, Promoting a Matrix?Preserving Nonmyofibroblast Phenotype, Without Stimulating Pericyte to Fibroblast Conversion - Linda Alex, Izabela Tuleta , Anis Hanna , and Nikolaos G. Frangogiannis 1 The Wilf Family Cardiovascular Research Institute Department of Medicine (Cardiology), Albert Einstein College of Medicine Bronx NY J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundInterstitial and perivascular fibrosis may contribute to diabetes?associated heart failure. Pericytes can convert to fibroblasts under conditions of stress and have been implicated in the pathogenesis of fibrotic diseases. We (...) (Journal of the American Heart Association)
12:41
Clinical Metabolomic Landscape of Cardiovascular Physiology and Disease - Keenan S. Fine, John T. Wilkins , and Konrad Teodor Sawicki 1 Feinberg School of Medicine Northwestern University Chicago IL USA 2 Department of Preventive Medicine, Feinberg School of Medicine Northwestern University Chicago IL USA 3 Division of Cardiology, Department of Medicine, Feinberg School of Medicine Northwestern University Chicago IL USA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:41
Diagnosis of Heart Failure With Preserved Ejection Fraction Relies on Detection of Increased Diastolic Filling Pressure, But How? - Jae K. Oh, William R. Miranda , and Garvan C. Kane 1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:39
Pathophysiological Gaps, Diagnostic Challenges, and Uncertainties in Cardiac Sarcoidosis - Laura Ueberham, Andreas Hagendorff , Karin Klingel , Ingo Paetsch , Cosima Jahnke , Theresa Kluge , Hans Ebbinghaus , Gerhard Hindricks , Ulrich Laufs , and Borislav Dinov 1 Klinik und Poliklinik für Kardiologie Universitätsklinikum Leipzig Leipzig Germany 2 Cardiopathology Institute for Pathology, Eberhard Karls Universität Tübingen Tübingen Germany 3 Department of Electrophysiology Heart Center Leipzig at University of Leipzig Leipzig Germany 4 Klinik und Poliklinik für Nuklearmedizin Universitätsklinikum Leipzig Leipzig (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. Cardiac sarcoidosis can mimic any cardiomyopathy in different stages. Noncaseating granulomatous inflammation can be missed, because of the nonhomogeneous distribution in the heart. The current diagnostic criteria show discrepancies and (...) (Journal of the American Heart Association)
12:46
Association of Objective and Self?Reported Sleep Duration With All?Cause and Cardiovascular Disease Mortality: A Community?Based Study - Binbin Zhao, Yuxuan Meng , Xiaoying Jin , Wenyu Xi , Qingyan Ma , Jian Yang , Xiancang Ma , and Bin Yan 1 Department of Psychiatry The First Affiliated Hospital of Xi’an Jiaotong University Xi’an China 2 Department of Brain Sciences Imperial College London London UK 3 Department of Clinical Research Center The First Affiliated Hospital of Xi’an Jiaotong University Xi’an China J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundPrevious studies found an association between self?reported sleep duration and mortality. This study aimed to compare the effects of objective and self?reported sleep duration on all?cause and cardiovascular disease (CVD) (...) (Journal of the American Heart Association)
12:45
Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension - Kevin Y. Chang, Katherine Giorgio , Katlin Schmitz , Rob F. Walker , Kurt W. Prins , Marc R. Pritzker , Stephen L. Archer , Pamela L. Lutsey , and Thenappan Thenappan 1 Cardiovascular Division, Department of Medicine University of Minnesota Minneapolis MN USA 2 Division of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA 3 Department of Medicine Queen’s University Kingston Ontario Canada J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundDigoxin acutely increases cardiac output in patients with pulmonary arterial hypertension (PAH) and right ventricular failure; however, the effects of chronic digoxin use in PAH are unclear.Methods and ResultsData from the (...) (Journal of the American Heart Association)
12:45
QRS Fragmentation in Preserved Ejection Fraction Heart Failure: Functional Insights, Pathological Correlates, and Prognosis - Kuo?Tzu Sung, Sheng?Hsiung Chang , Po?Ching Chi , Shih?Chieh Chien , Chi?In Lo , Chao?Feng Lin , Wen?Hung Huang , Chun?Ho Yun , Cheng?Ting Tsai , Cheng?Huang Su , Charles Jia?Yin Hou , Hung?I Yeh , Chin?Ho Tsao , Jen?Yuan Kuo , and Chung?Lieh Hung 1 Department of Internal Medicine, Cardiovascular Center and Division of Cardiology MacKay Memorial Hospital Taipei Taiwan (R.O.C) 2 MacKay Medical College New Taipei City Taiwan (R.O.C.) 3 Mackay Junior College of Medicine, Nursing and Management New Taipei city Taiwan (R.O.C.) 4 Division of Radiology MacKay Memorial Hospital Taipei Taiwan (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundFragmented QRS (fQRS) morphology as a surrogate marker of the possible presence of myocardial scarring has been shown to confer a higher risk in patients with reduced ejection fraction heart failure. We aimed to investigate (...) (Journal of the American Heart Association)
12:44
Burden, Trends, and Inequalities of Heart Failure Globally, 1990 to 2019: A Secondary Analysis Based on the Global Burden of Disease 2019 Study - Tao Yan, Shijie Zhu , Xiujie Yin , Changming Xie , Junqiang Xue , Miao Zhu , Fan Weng , Shichao Zhu , Bitao Xiang , Xiaonan Zhou , Gang Liu , Yang Ming , Kai Zhu , Chunsheng Wang , and Changfa Guo 1 Department of Cardiovascular Surgery Zhongshan Hospital, Fudan University Shanghai China 2 Department of Cardiology The Eighth Affiliated Hospital, Sun Yat?sen University Shenzhen Guangdong China 3 Department of Cardiology Zhongshan Hospital, Fudan University Shanghai (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundHeart failure is a public health issue worldwide. However, no comprehensive study on the global burden of heart failure and its contributing causes has been reported. The present study aimed to quantify the burden, trends, and (...) (Journal of the American Heart Association)
12:44
Preferences of Patients With Chronic Kidney Disease for Invasive Versus Conservative Treatment of Acute Coronary Syndrome: A Discrete Choice Experiment - Todd A. Wilson, Glen S. Hazlewood , Tolulope T. Sajobi , Stephen B. Wilton , Winnie E. Pearson , Carol Connolly , Pantea A. Javaheri , Juli L. Finlay , Adeera Levin , Michelle M. Graham , Marcello Tonelli , and Matthew T. James 1 Department of Medicine University of Calgary Calgary Alberta Canada 2 Department of Community Health Sciences University of Calgary Calgary Alberta Canada 3 Department of Cardiac Sciences University of Calgary Calgary Alberta Canada 4 Division of Nephrology University of British Columbia Vancouver British Columbia Canada 5 Patient and Community Engagement (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundPatients with chronic kidney disease (CKD) can experience acute coronary syndromes (ACS) with high morbidity and mortality. Early invasive management of ACS is recommended for most high?risk patients; however, choosing between (...) (Journal of the American Heart Association)
12:44
Attenuation of Hypocretin/Orexin Signaling Is Associated With Increased Mortality After Myocardial Infarction - Peter Wohlfahrt, Dominik Jen?a , Vojt?ch Melenovský , Petr Jarolím , Dana Dlouhá , Marek Šramko , Martin Kotr? , Michael Želízko , Jolana Mrázková , Jan Pi?ha , V?ra Adámková , and Josef Kautzner 1 Department of Preventive Cardiology Institute for Clinical and Experimental Medicine (IKEM) Prague Czech Republic 2 First Medical School Charles University Prague Czech Republic 3 Department of Cardiology Institute for Clinical and Experimental Medicine (IKEM) Prague Czech Republic 4 Third Medical School Charles University Prague Czech Republic 5 Department of Pathology Brigham and Women’s Hospital (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe hypocretin/orexin system has been shown to play a role in heart failure. Whether it also influences myocardial infarction (MI) outcomes is unknown. We evaluated the effect of the rs7767652 minor allele T associated with (...) (Journal of the American Heart Association)
12:43
Association of Joint Genetic and Social Environmental Risks With Incident Myocardial Infarction: Results From the Health and Retirement Study - Junhan Tang, Chen Sheng , Yan Yan Wu , Lijing L. Yan , and Chenkai Wu 1 Global Health Research Center Duke Kunshan University Kunshan Jiangsu China 2 Shanghai Medical College Fudan University Shanghai China 3 Thompson School of Social Work & Public Health University of Hawai?i at M?noa HI Honolulu USA 4 Duke Global Health Institute Duke University Durham NC USA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundMyocardial infarction (MI) is a significant clinical and public health problem worldwide. However, little research has assessed the interplay between genetic susceptibility and social environment in the development of (...) (Journal of the American Heart Association)
12:43
Heat Exposure Following the Rainy Season Is Associated With an Increased Risk of Cardiovascular Emergency Among the Elderly in Japan - Ryohei Fujimoto, Etsuji Suzuki , Saori Kashima , Kazufumi Nakamura , Hiromichi Naito , Atsunori Nakao , Hiroshi Ito , and Takashi Yorifuji 1 Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan 2 Department of Cardiovascular Medicine Tsuyama Chuo Hospital Tsuyama Okayama Japan 3 Department of Epidemiology Harvard T.H. Chan School of Public Health Boston MA USA 4 Environmental Health Sciences Laboratory, Graduate School of Advanced Science and Engineering Hiroshima University Hiroshima Japan 5 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundDespite the impact of heat exposure caused by global warming, few studies have investigated the hourly effects of heat exposure and the risk of cardiovascular disease (CVD) in the elderly. We examined the associations between (...) (Journal of the American Heart Association)
12:42
Preadmission Opioid Use and 1?Year Mortality Following Incident Myocardial Infarction: A Danish Population?Based Cohort Study (1997–2016) - Søren Korsgaard, Troels Munch , Erzsébet Horváth–Puhó , Kasper Adelborg , Christian Fynbo Christiansen , Lars Pedersen , Morten Schmidt , and Henrik Toft Sørensen 1 Department of Clinical Epidemiology Aarhus University Hospital Aarhus Denmark 2 Department of Clinical Medicine Aarhus University Aarhus Denmark 3 Department of Clinical Biochemistry, Thrombosis and Hemostasis Research Unit Aarhus University Hospital Aarhus Denmark 4 Department of Cardiology Aarhus University Hospital Aarhus (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundOpioid use has been linked to an increased risk of myocardial infarction and cardiovascular mortality, but the prognostic impact of opioid use before an incident myocardial infarction is largely unknown.Methods and ResultsWe (...) (Journal of the American Heart Association)
12:42
Family History of Modifiable Risk Factors and Association With Future Cardiovascular Disease - Christy N. Taylor, Dongyu Wang , Martin G. Larson , Emily S. Lau , Emelia J. Benjamin , Ralph B. D'Agostino , Ramachandran S. Vasan , Daniel Levy , Susan Cheng , and Jennifer E. Ho 1 Department of Medicine Massachusetts General Hospital Boston MA 2 Harvard Medical School Boston MA 3 Division of Cardiovascular Medicine Beth Israel Deaconess Medical Center Boston MA 4 Department of Biostatistics Boston University School of Public Health Boston MA 5 Division of Cardiology Massachusetts General Hospital Boston MA 6 Section of Cardiovascular Medicine, Boston Medical Center Boston University (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundA parental history of cardiovascular disease (CVD) confers greater risk of future CVD among offspring. Whether the presence of parental modifiable risk factors contribute to or modify CVD risk in offspring is unclear.Methods (...) (Journal of the American Heart Association)
12:41
Mitochondrial Complex Abundance, Mitophagy Proteins, and Physical Performance in People With and Without Peripheral Artery Disease - Anna Picca, Stephanie E. Wohlgemuth , Mary M. McDermott , Sunil K. Saini , Sudarshan Dayanidhi , Dongxue Zhang , Shujun Xu , Kate Kosmac , Lu Tian , Luigi Ferrucci , Robert L. Sufit , Emanuele Marzetti , and Christiaan Leeuwenburgh 1 Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS Rome Italy 2 Department of Medicine and Surgery LUM University Casamassima Italy 3 Department of Physiology and Aging University of Florida, Institute on Aging Gainesville FL USA 4 Department of Preventive Medicine Northwestern University, Feinberg School of Medicine Chicago IL USA 5 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundMitochondrial abnormalities exist in gastrocnemius muscle of people with peripheral artery disease (PAD). Whether abnormalities in mitochondrial biogenesis and autophagy are associated with greater ischemia or walking (...) (Journal of the American Heart Association)
12:41
Myocardial Tissue Characterization in Cardiac Magnetic Resonance Studies of Patients Recovering From COVID?19: A Meta?Analysis - Michael Jerosch?Herold, Carsten Rickers , Steffen E. Petersen , and Otávio R. Coelho?Filho 1 Department of Radiology, Cardiovascular Imaging Section Brigham and Women’s Hospital Boston MA 2 Children’s Heart Clinic, Adult Congenital Heart Disease Section University Hospital Hamburg?Eppendorf (UKE) Hamburg Germany 3 William Harvey Research Institute NIHR Barts Biomedical Research Centre, Queen Mary University London, Charterhouse Square London United Kingdom 4 Barts Heart Centre, St Bartholomew’s Hospital Barts Health NHS Trust London United Kingdom 5 Department of Internal Medicine State (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundMeta?analysis can identify biological factors that moderate cardiac magnetic resonance myocardial tissue markers such as native T1(longitudinal magnetization relaxation time constant) and T2(transverse magnetization relaxation (...) (Journal of the American Heart Association)
12:40
NLRP3 Inflammasome Activation in Peripheral Arterial Disease - Francesca Bartoli?Leonard, Jonas Zimmer , Abhijeet R. Sonawane , Katelyn Perez , Mandy E. Turner , Shiori Kuraoka , Tan Pham , Feifei Li , Masanori Aikawa , Sasha Singh , Luke Brewster , and Elena Aikawa 1 Division of Cardiovascular Medicine, Department of Medicine, Center for Interdisciplinary Cardiovascular Sciences Brigham and Women’s Hospital, Harvard Medical School Boston MA USA 2 Division of Cardiovascular Medicine, Department of Medicine, Center for Excellence in Vascular Biology Brigham and Women’s Hospital, Harvard Medical School Boston MA USA 3 Department of Surgery Emory (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundPeripheral arterial disease (PAD) is estimated to affect 7% of the adult population in the United States; however, there is currently little understanding of the key cellular and molecular pathways at play. With PAD (...) (Journal of the American Heart Association)
12:40
Arrhythmogenic Cardiotoxicity Associated With Contemporary Treatments of Lymphoproliferative Disorders - Saadia Sherazi, Susan Schleede , Scott McNitt , Carla Casulo , Jeremiah E. Moore , Eugene Storozynsky , Arpan Patel , Neelima Vidula , Mehmet K. Aktas , Clive S. Zent , and Ilan Goldenberg 1 Division of Cardiology Clinical Cardiovascular Research Center University of Rochester School of Medicine and Dentistry Rochester NY 2 Division of Hematology/Oncology and Wilmot Cancer Institute University of Rochester School of Medicine and Dentistry Rochester NY 3 Thomas Jefferson University Hospital Philadelphia PA 4 Massachusetts General Hospital Cancer Center Harvard Medical School Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThere are limited data on risk of arrhythmias among patients with lymphoproliferative disorders. We designed this study to determine the risk of atrial and ventricular arrhythmia during treatment of lymphoma in a real?world (...) (Journal of the American Heart Association)
12:40
Association of Thoracic Aortic Aneurysm Versus Aortic Dissection on Outcomes After Thoracic Endovascular Aortic Repair - Irsa S. Hasan, James A. Brown , Derek Serna?Gallegos , Edgar Aranda?Michel , Sarah Yousef , Yisi Wang , and Ibrahim Sultan 1 Division of Cardiac Surgery, Department of Cardiothoracic Surgery University of Pittsburgh PA USA 2 Heart and Vascular Institute University of Pittsburgh Medical Center PA USA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundBecause thoracic endovascular aortic repair (TEVAR) has become the standard of care for complicated type B aortic dissection (TBAD) and descending thoracic aortic (DTA) aneurysm, it is important to understand outcomes and use (...) (Journal of the American Heart Association)
12:40
Impact of Neighborhood Socioeconomic Status on Outcomes Following First?Stage Palliation of Single Ventricle Heart Disease - Aditya Sengupta, Emily M. Bucholz , Kimberlee Gauvreau , Jane W. Newburger , Margaret Schroeder , Aditya K. Kaza , Pedro J. del Nido , and Meena Nathan 1 Department of Cardiac Surgery Boston Children’s Hospital Boston MA 2 Department of Cardiology Boston Children’s Hospital Boston MA 3 Department of Biostatistics Harvard School of Public Health Boston MA 4 Department of Pediatrics Harvard Medical School Boston MA 5 Department of Surgery Harvard Medical School Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe impact of neighborhood socioeconomic status (SES) on outcomes following first?stage palliation of single ventricle heart disease remains incompletely characterized.Methods and ResultsThis was a single?center, retrospective (...) (Journal of the American Heart Association)
12:37
Relationship Between Left Ventricular Hypertrophy and Diabetes Is Likely Bidirectional: A Temporality Analysis - Jiali Lv, Yang Liu , Yinkun Yan , Dianjianyi Sun , Lijun Fan , Yajun Guo , Camilo Fernandez , Lydia Bazzano , Jiang He , Shengxu Li , Wei Chen , and Tao Zhang 1 Department of Biostatistics, School of Public Health Cheeloo College of Medicine, Shandong University Jinan Shandong China 2 Department of Cardiology The First Affiliated Hospital of Soochow University Suzhou China 3 Center for Non?Communicable Disease Management, Beijing Children’s Hospital Capital Medical University, National Center for Children’s Health Beijing China 4 Department of Epidemiology and Biostatistics School of Public (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe temporal relationship between type 2 diabetes (T2DM) and left ventricular hypertrophy (LVH) is not well established. This study aims to examine the temporal sequence between T2DM and LVH/cardiac geometry patterns in (...) (Journal of the American Heart Association)
12:37
Myocardial Revascularization in Patients With Ischemic Cardiomyopathy: For Whom and How - Riccardo Liga, Andrea Colli , David P. Taggart , William E. Boden , and Raffaele De Caterina 1 Cardiology Division, Pisa University Hospital and Chair of Cardiology University of Pisa Italy 2 Nuffield Department of Surgical Sciences Oxford University John Radcliffe Hospital Oxford United Kingdom 3 VA Boston Healthcare System Boston University School of Medicine Boston MA 4 Fondazione VillaSerena per la Ricerca, Città Sant'Angelo Italy J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundMyocardial revascularization has been advocated to improve myocardial function and prognosis in ischemic cardiomyopathy (ICM). We discuss the evidence for revascularization in patients with ICM and the role of ischemia and (...) (Journal of the American Heart Association)
12:37
Comparison of Questionnaire and Performance?Based Physical Frailty Scales to Predict Survival and Health?Related Quality of Life in Patients With Heart Failure - Joseph Somech, Aayushi Joshi , Rita Mancini , Jessica Chetrit , Caroline Michel , Richard Sheppard , Viviane Nguyen , Mathieu Walker , Nadia Giannetti , Abhinav Sharma , Delina Maghakian , Esther Laforest , and Jonathan Afilalo 1 Division of Experimental Medicine McGill University Montreal Quebec Canada 2 Centre for Clinical Epidemiology Jewish General Hospital Montreal Quebec Canada 3 Division of Cardiology Jewish General Hospital, McGill University Montreal Quebec Canada 4 Division of Cardiology Hôpital de la Cité?de?la?Santé de Laval, Université de Montréal Montreal Quebec Canada 5 Division (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundFrailty is prevalent in older adults with heart failure and is associated with poor outcomes; however, there remains uncertainty on how to measure frailty in clinical practice.Methods and ResultsA multicentric prospective (...) (Journal of the American Heart Association)
12:37
Discriminative Role of Invasive Left Heart Catheterization in Patients Suspected of Heart Failure With Preserved Ejection Fraction - Ki Hong Choi, Jeong Hoon Yang , Jeong Hun Seo , David Hong , Taeho Youn , Hyun Sung Joh , Seung Hun Lee , Darae Kim , Taek Kyu Park , Joo Myung Lee , Young Bin Song , Jin?Oh Choi , Joo?Yong Hahn , Seung?Hyuk Choi , Hyeon?Cheol Gwon , and Eun?Seok Jeon 1 Division of Cardiology, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea 2 Department of Critical Care Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Republic of Korea 3 Division of Cardiology, Department of Medicine Kangwon National (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundRecently, diastolic stress testing and invasive hemodynamic measurements have been emphasized for diagnosis of heart failure with preserved ejection fraction (HFpEF) because when determined using noninvasive parameters it can (...) (Journal of the American Heart Association)
12:37
Urine Cell Transcriptomes Implicate Specific Renal Inflammatory Pathways Associated With Difficult?to?Control Hypertension - Kausik Umanath, Ruicong She , Clare Hassett , Indra Adrianto , Albert M. Levin , Gina Savickas , Jerry Yee , and Pablo Ortiz 1 Division of Nephrology and Hypertension Henry Ford Health Detroit MI 2 Division of Nephrology and Hypertension Wayne State University Detroit MI 3 Department of Medicine Michigan State University East Lansing MI 4 Department of Public Health Sciences Henry Ford Health Detroit MI 5 Center for Bioinformatics Henry Ford Health Detroit MI 6 Translation and Clinical Research Center Henry Ford Hospital Detroit MI 7 Division of Hypertension and Vascular Research Henry (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe renal mechanisms involved in the maintenance of human hypertension and resistance to treatment are not well understood. Animal studies suggest that chronic renal inflammation contributes to hypertension. We studied cells (...) (Journal of the American Heart Association)

8 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

10:24
Incident Atrial Fibrillation and Risk of Dementia in a Diverse, Community?Based Population - Nisha Bansal, Leila R. Zelnick , Jaejin An , Teresa N. Harrison , Ming?Sum Lee , Daniel E. Singer , Dongjie Fan , and Alan S. Go 1 Division of Nephrology Kidney Research Institute, University of Washington Seattle WA USA 2 Department of Research and Evaluation Kaiser Permanente Southern California Pasadena CA USA 3 Department of Health Systems Science Kaiser Permanente Bernard J. Tyson School of Medicine Pasadena CA USA 4 Clinical Epidemiology Unit Massachusetts General Hospital Boston MA USA 5 Harvard Medical School Boston MA USA 6 Division of Research Kaiser Permanente Northern (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundAtrial fibrillation (AF) is the most common, clinically relevant arrhythmia in adults and associated with ischemic stroke and premature death. However, data are conflicting on whether AF is independently associated with risk (...) (Journal of the American Heart Association)

7 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

04:44
Impact of Diabetes and Hypertension on Left Ventricular Structure and Function: The Jackson Heart Study - Arsalan Hamid, Wondwosen K. Yimer , Adebamike A. Oshunbade , Daisuke Kamimura , Donald Clark , Ervin R. Fox , Yuan?I Min , Paul Muntner , Daichi Shimbo , Ambarish Pandey , Amil M. Shah , Robert J. Mentz , Daniel W. Jones , Alain G. Bertoni , John E. Hall , Adolfo Correa , Javed Butler , and Michael E. Hall 1 Department of Medicine University of Mississippi Medical Center Jackson MS 2 Department of Data Science University of Mississippi Medical Center Jackson MS 3 Division of Cardiology, Department of Medicine University of Mississippi Medical Center Jackson MS 4 Department of Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundDiabetes and hypertension have been associated with adverse left ventricular (LV) remodeling. While they often occur concurrently, their individual effects are understudied. We aimed to assess the independent effects of (...) (Journal of the American Heart Association)

5 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

03:29
Antithrombotic Treatment, Prehospital Blood Pressure, and Outcomes in Spontaneous Intracerebral Hemorrhage - Kristin Tveitan Larsen, Else Charlotte Sandset , Maiken Nordahl Selseth , Silje Holt Jahr , Nojoud Koubaa , Vigdis Hillestad , Espen Saxhaug Kristoffersen , and Ole Morten Rønning 1 Department of Neurology Akershus University Hospital Lørenskog Norway 2 Department of Geriatric Medicine Oslo University Hospital Oslo Norway 3 University of Oslo, Institute of Clinical Medicine Oslo Norway 4 Department of Neurology Oslo University Hospital Oslo Norway 5 The Norwegian Air Ambulance Foundation Oslo Norway 6 Department of Diagnostic Imaging Akershus University Hospital Lørenskog Norway 7 Department (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundIn acute intracerebral hemorrhage, both elevated blood pressure (BP) and antithrombotic treatment are associated with poor outcome. Our aim was to explore interactions between antithrombotic treatment and (...) (Journal of the American Heart Association)
03:28
Associations of Modified Healthy Aging Index With Major Adverse Cardiac Events, Major Coronary Events, and Ischemic Heart Disease - Ninghao Huang, Zhenhuang Zhuang , Zimin Song , Wenxiu Wang , Yueying Li , Yimin Zhao , Wendi Xiao , Xue Dong , Jinzhu Jia , Zhonghua Liu , Caren E. Smith , and Tao Huang 1 Department of Epidemiology and Biostatistics, School of Public Health Peking University Beijing China 2 Department of Biostatistics, School of Public Health Peking University Beijing China 3 Department of Biostatistics Columbia University NY New York 4 Nutrition and Genomics Laboratory JM?USDA Human Nutrition Research Center on Aging at Tufts University Boston MA 5 State Key Laboratory of Remote Sensing Science, Faculty (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundThe Healthy Aging Index (HAI) has been regarded as useful in capturing the health status of multiple organ systems. However, to what extent the HAI is associated with major cardiovascular events remains (...) (Journal of the American Heart Association)
03:28
Implementation of Ticagrelor Reduced Mortality in Routine Clinical Care: Evidence From a Natural Experiment Including 109 995 Patients With Myocardial Infarction in Sweden - Kasper Johannesen, Jonathan Siverskog , Martin Henriksson , Magnus Janzon , Bertil Lindahl , and Erik Grönqvist 1 Centre for Medical Technology Assessment, Department of Health, Medicine and Caring Sciences Linköping University Linköping Sweden 2 Centre for Health Economic Research Uppsala University Uppsala Sweden 3 Department of Medical Sciences Uppsala University Uppsala Sweden 4 Department of Cardiology University Hospital Linköping Sweden 5 Division of Diagnostics and Specialist Medicine, Department of Health, Medicine and Caring Sciences Linköping University Linköping Sweden 6 Department (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundEffectiveness estimates from observational studies on ticagrelor use in routine clinical care are conflicting, with some contrary to the results of the pivotal randomized controlled trial of ticagrelor in (...) (Journal of the American Heart Association)
03:27
Correction to: How Well Do ICD?9?CM Codes Predict True Congenital Heart Defects? A Centers for Disease Control and Prevention?Based Multisite Validation Project J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)
03:27
Variability in Lipid Levels and Risk for Cardiovascular Disease: An Electronic Health Record–Based Population Cohort Study - Sheila M. Manemann, Suzette J. Bielinski , Ethan D. Moser , Jennifer L. St. Sauver , Paul Y. Takahashi , Véronique L. Roger , Janet E. Olson , Alanna M. Chamberlain , Alan T. Remaley , Paul A. Decker , Jill M. Killian , and Nicholas B. Larson 1 Department of Quantitative Health Sciences Mayo Clinic Rochester MN 2 Division of Community Internal Medicine, Department of Medicine Mayo Clinic Rochester MN 3 Department of Cardiovascular Medicine Mayo Clinic Rochester MN 4 Epidemiology and Community Health Branch National Institutes of Health Bethesda MD 5 Lipoprotein Metabolism Laboratory, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundLarger within?patient variability of lipid levels has been associated with increased risk of cardiovascular disease (CVD); however, measures of lipid variability require ?3 measurements and are not currently (...) (Journal of the American Heart Association)
03:26
Always Look on the Bright Side: Associations of Optimism With Functional Outcomes After Stroke - Kelly L. Sloane, Scott E. Kasner , Christopher G. Favilla , Aaron Rothstein , Jens Witsch , Roy H. Hamilton , and Andrea L. C. Schneider 1 Department of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA 2 Department of Physical Medicine and Rehabilitation University of Pennsylvania Perelman School of Medicine Philadelphia PA USA 3 Department of Biostatistics, Epidemiology, and Informatics University of Pennsylvania Perelman School of Medicine Philadelphia PA (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundPsychological health is as an important contributor to recovery after cardiovascular disease, but the roles of both optimism and depression in stroke recovery are not well characterized.Methods and ResultsA (...) (Journal of the American Heart Association)

3 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

07:34
Sex Differences in Oral Anticoagulation Therapy in Patients Hospitalized With Atrial Fibrillation: A Nationwide Cohort Study - Kuan Ken Lee, Dimitrios Doudesis , Rong Bing , Federica Astengo , Jesus R. Perez , Atul Anand , Shauna McIntyre , Nicholas Bloor , Belinda Sandler , Steven Lister , Kevin G. Pollock , Ayesha C. Qureshi , David A. McAllister , Anoop S. V. Shah , and Nicholas L. Mills 1 BHF Centre for Cardiovascular Science University of Edinburgh Edinburgh United Kingdom 2 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh Edinburgh United Kingdom 3 Institute of Health and Wellbeing, University of Glasgow Glasgow United Kingdom 4 Bristol Myers Squibb Pharmaceuticals Ltd (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundImportant disparities in the treatment and outcomes of women and men with atrial fibrillation (AF) are well recognized. Whether introduction of direct oral anticoagulants has reduced disparities in treatment (...) (Journal of the American Heart Association)

1 March

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:04
Association of Home?Based Cardiac Rehabilitation With Lower Mortality in Patients With Cardiovascular Disease: Results From the Veterans Health Administration Healthy Heart Program - Nirupama Krishnamurthi, David W. Schopfer , Hui Shen , Gregory Rohrbach , Abdelaziz Elnaggar , and Mary A. Whooley 1 Icahn School of Medicine at Mount Sinai New York NY 2 Department of Cardiology Mount Sinai Morningside New York NY 3 San Francisco Veterans Affairs Medical Center San Francisco CA 4 National Institutes of Health Bethesda MD 5 Department of Medicine University of California San Francisco CA 6 Department of Epidemiology and Biostatistics University of California San Francisco San Francisco (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundHome?based cardiac rehabilitation (HBCR) and traditional facility?based cardiac rehabilitation (CR) programs have similar effects on mortality in clinical trials and meta?analyses. However, the effect of HBCR (...) (Journal of the American Heart Association)

27 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:12
Cardio?Obstetrics: Moving Beyond Programming to Action - Cornelia R. Graves, Ruth M. Woldemichael , and Stacy F. Davis 1 Collaborative Perinatal Cardiac Center St. Thomas Health Systems Nashville TN USA 2 University of Tennessee Health Science Center–Nashville Ascension St. Thomas Midtown Hospital Nashville TN USA 3 St Thomas Midtown Comprehensive Heart Failure Center St. Thomas Health Systems Nashville TN USA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)
11:23
Women's Reproductive Milestones and Cardiovascular Disease Risk: A Review of Reports and Opportunities From the CARDIA Study - Catherine Kim, Janet Catov , Pamela J. Schreiner , Duke Appiah , Melissa F. Wellons , David Siscovick , Ronit Calderon?Margalit , Heather Huddleston , Imo Asuquo Ebong , and Cora E. Lewis 1 Departments of Medicine, Obstetrics and Gynecology, and Epidemiology University of Michigan Ann Arbor MI 2 Department of Obstetrics, Gynecology and Reproductive Sciences University of Pittsburgh Pittsburgh PA 3 Division of Epidemiology and Community Health University of Minnesota Minneapolis MN 4 Department of Public Health, Graduate School of Biomedical Sciences Texas Tech University Lubbock TX 5 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. In 1985 to 1986, the CARDIA (Coronary Artery Risk Development in Young Adults) study enrolled 5115 Black or White participants, including 2788 women, aged 18 to 30 years. Over the following 35 years, the CARDIA study (...) (Journal of the American Heart Association)
11:22
Contributions of Women to Cardiovascular Science Over Two Decades: Authorship, Leadership, and Mentorship - Vanessa Blumer, Ilya Y. Zhbannikov , and Pamela S. Douglas 1 Department of Cardiovascular Medicine, Section of Advanced Heart Failure and Transplant Cardiology Cleveland Clinic Foundation Cleveland OH USA 2 Duke University Clinical Research Institute Durham NC USA 3 Division of Cardiology, Department of Medicine Duke University Medical Center Durham NC USA 4 Center of Applied Genomics and Precision Medicine Duke University Durham NC USA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundWomen remain underrepresented in cardiology. We aimed to assess gender trends in research authorship, authorship in leading roles, mentorship, and research team diversity.Methods and ResultsWe identified (...) (Journal of the American Heart Association)
11:22
Mediation Effect of Obesity on the Association of Age at Menarche With Blood Pressure Among Women in Southwest China - Jiayi Chen, Mingxia Yan , Deji Suolang , Mingming Han , Yangji Baima , Fei Mi , Liling Chen , Han Guan , Hui Cai , Xing Zhao , and Qiaolan Liu 1 West China School of Public Health and West China Fourth Hospital, Sichuan University Chengdu China 2 Tibet Center for Disease Control and Prevention Lhasa China 3 Chengdu Center for Disease Control and Prevention Chengdu China 4 School of Medicine Tibet University Lhasa China 5 School of Public Health Kunming Medical University Kunming China 6 Chongqing Municipal Center for Disease Control and Prevention Chongqing China 7 School of Public (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundPrevious studies have been inconsistent about the association between age at menarche and high blood pressure. Little is known about such association across a wide range of menarcheal ages in less developed (...) (Journal of the American Heart Association)
11:19
Third?Trimester Maternal Serum Chemerin and Hypertension After Preeclampsia: A Prospective Cohort Study - Yixuan Chen, Linlin Wu , Hangkuan Liu , Ziping Li , Linjie Li , Xiaoxia Wu , Qiong Lei , Aiqi Yin , Jianing Tong , Kan Liu , Xiaonian Guan , Cuiping Zeng , Huafan Zhang , Yanmei Wan , Xuna Huang , Pingping Huang , Qing Yang , Xin Zhou , and Jianmin Niu 1 Department of Obstetrics Shenzhen Maternity and Child Healthcare Hospital Shenzhen Guangdong China 2 The First School of Clinical Medicine Southern Medical University Shenzhen Guangdong China 3 Department of Obstetrics and Gynecology, the Eighth Affiliated Hospital Sun Yat?sen University Shenzhen Guangdong China 4 Department of Cardiology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundLimited data are available for postpartum hypertension prediction after preeclampsia.Methods and ResultsWe examined the association between maternal serum chemerin levels in patients with preeclampsia and (...) (Journal of the American Heart Association)
11:17
Social Determinants, Blood Pressure Control, and Racial Inequities in Childbearing Age Women With Hypertension, 2001 to 2018 - Claire V. Meyerovitz, Stephen P. Juraschek , Didem Ayturk , Tiffany A. Moore Simas , Sharina D. Person , Stephenie C. Lemon , David D. McManus , and Lara C. Kovell 1 UMass Chan Medical School Worcester MA 2 Division of General Medicine Beth Israel Deaconess Medical Center/Harvard Medical School Boston MA 3 Department of Population and Quantitative Health Sciences UMass Chan Medical School Worcester MA 4 Departments of Obstetrics and Gynecology, Pediatrics and Psychiatry UMass Chan Medical School Worcester MA 5 Division of Cardiovascular Medicine, Department of Medicine UMass Chan Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundHypertension is an important modifiable risk factor of serious maternal morbidity and mortality. Social determinants of health (SDoH) influence hypertension outcomes and may contribute to racial and ethnic (...) (Journal of the American Heart Association)
11:17
Group Dynamics and Allocation of Advanced Heart Failure Therapies—Heart Transplants and Ventricular Assist Devices—By Gender, Racial, and Ethnic Group - Khadijah Breathett, Ryan Yee , Natalie Pool , Megan C. Thomas Hebdon , Shannon M. Knapp , Kathryn Herrera?Theut , Esther de Groot , Erika Yee , Larry A. Allen , Ayesha Hasan , JoAnn Lindenfeld , Elizabeth Calhoun , Molly Carnes , and Nancy K. Sweitzer 1 Division of Cardiovascular Medicine Indiana University Indianapolis IN 2 Division of Cardiovascular Medicine, Research Team Indiana University Indianapolis IN 3 School of Nursing University of Northern Colorado Greeley CO 4 School of Nursing University of Texas Austin TX 5 Department of Medicine/Pediatrics University of Michigan Ann Arbor (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundUS regulatory framework for advanced heart failure therapies (AHFT), ventricular assist devices, and heart transplants, delegate eligibility decisions to multidisciplinary groups at the center level. The (...) (Journal of the American Heart Association)
11:16
Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female?Specific Health Conditions - Brenda Xiao, Digna R. Velez Edwards , Anastasia Lucas , Theodore Drivas , Kathryn Gray , Brendan Keating , Chunhua Weng , Gail P. Jarvik , Hakon Hakonarson , Leah Kottyan , Noemie Elhadad , Wei?Qi Wei , Yuan Luo , Dokyoon Kim , Marylyn Ritchie , Shefali Setia Verma 1 Graduate Program in Genomics and Computational Biology University of Pennsylvania Philadelphia PA 2 Division of Quantitative Sciences, Department of Obstetrics and Gynecology Vanderbilt University Medical Center Nashville TN 3 Department of Genetics University of Pennsylvania Philadelphia PA 4 Department of Obstetrics and (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundCardiometabolic diseases are highly comorbid, but their relationship with female?specific or overwhelmingly female?predominant health conditions (breast cancer, endometriosis, pregnancy complications) is (...) (Journal of the American Heart Association)
11:16
Breastfeeding and Later?Life Cardiometabolic Health in Women With and Without Hypertensive Disorders of Pregnancy - Maria C. Magnus, McKenzie K. Wallace , Jill R. Demirci , Janet M. Catov , Mandy J. Schmella , and Abigail Fraser 1 Center for Fertility and Health Norwegian Institute of Public Health Oslo Norway 2 MRC Integrative Epidemiology Unit at the University of Bristol Bristol United Kingdom 3 Population Health Sciences Bristol Medical School Bristol United Kingdom 4 Martha S. Pitzer Center for Women, Children and Youth, College of Nursing The Ohio State University Columbus OH 5 School of Nursing University of Pittsburgh Pittsburgh PA 6 Department of Epidemiology University of Pittsburgh (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundBreastfeeding is associated with improved cardiometabolic profiles decades after pregnancy. Whether this association exists for women who experience hypertensive disorders of pregnancy (HDP) is unknown. The (...) (Journal of the American Heart Association)
11:15
Infertility and Risk of Cardiovascular Disease: A Prospective Cohort Study - Leslie V. Farland, Yi?Xin Wang , Audrey J. Gaskins , Janet W. Rich?Edwards , Siwen Wang , Maria Christine Magnus , Jorge E. Chavarro , Kathryn M. Rexrode , and Stacey A. Missmer 1 Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health University of Arizona Tucson AZ 2 Department of Obstetrics and Gynecology, College of Medicine?Tucson University of Arizona Tucson AZ 3 Department of Nutrition Harvard T.H. Chan School of Public Health Boston MA 4 Department of Epidemiology, Rollins School of Public Health Emory University Atlanta GA 5 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundCertain symptoms associated with infertility are associated with cardiovascular disease, including menstrual cycle irregularity, early menopause, and obesity; however, few studies have investigated the (...) (Journal of the American Heart Association)
11:15
Sex Differences in Temporal Trends and Risk Factors of Aortic Dissection in Taiwan - Cherry Yin?Yi Chang, Ching?Feng Wu , Chih?Hsin Muo , Shih?Sheng Chang , and Pei?Chun Chen 1 Department of Obstetrics and Gynaecology China Medical University Hospital Taichung Taiwan 2 Department of Medicine, School of Medicine China Medical University Taichung Taiwan 3 Department of Surgery China Medical University Hospital Taichung Taiwan 4 Department of Public Health China Medical University Taichung Taiwan 5 Division of Cardiovascular Medicine China Medical University Hospital Taichung Taiwan 6 School of Medicine, College of Medicine China Medical University Taichung (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundAlthough sex differences in the epidemiological features of aortic dissection (AD) are known, whether there were sex differences in the associations of comorbidities and risk factors with AD is unclear. We (...) (Journal of the American Heart Association)
11:15
Sex?Specific Risk Factors for Deep Venous Thrombosis and Pulmonary Embolism in a Population?Based Historical Cohort Study of Middle?Aged and Older Individuals - Annie Brink, Johan Elf , Peter J. Svensson , Gunnar Engström , Olle Melander , and Bengt Zöller 1 Center for Primary Health Care Research Lund University and Region Skåne Malmö Sweden 2 Department of Clinical Sciences Lund University, Skåne University Hospital Malmö Sweden J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundWhether sex?specific differences exist for risk factors for pulmonary embolism (PE) and deep venous thrombosis (DVT), with the exception of pregnancy and estrogen therapy, has been sparsely studied. We aimed (...) (Journal of the American Heart Association)
11:14
Sex?Specific Reproductive Factors Augment Cardiovascular Disease Risk in Women: A Mendelian Randomization Study - Maddalena Ardissino, Eric A. W. Slob , Paul Carter , Tormod Rogne , Joanna Girling , Stephen Burgess , and Fu Siong Ng 1 National Heart and Lung Institute Imperial College London London United Kingdom 2 Nuffield Department of Population Health University of Oxford Oxford United Kingdom 3 Medical Research Council Biostatistics Unit University of Cambridge Cambridge United Kingdom 4 Department of Applied Economics, Erasmus School of Economics Erasmus University Rotterdam Rotterdam The Netherlands 5 Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundObservational studies suggest that reproductive factors are associated with cardiovascular disease, but these are liable to influence by residual confounding. This study explores the causal relevance of (...) (Journal of the American Heart Association)
11:14
Trends and Outcomes of ST?Segment–Elevation Myocardial Infarction Among Young Women in the United States - Temidayo Abe, Titilope Olanipekun , Demilade Adedinsewo , Oluseye Ogunmoroti , Ndausung Udongwo , Valery Effoe , Bria Rice , Ifeoma Onuorah , Jalal K. Ghali , Puja K. Mehta , and Erin D. Michos 1 Division of Cardiology, Department of Medicine Vanderbilt University School of Medicine Nashville TN 2 Department of Cardiovascular Medicine Mayo Clinic Jacksonville FL 3 Division of Cardiology, Department of Medicine Johns Hopkins School of Medicine Baltimore MD 4 Division of General Internal Medicine, Department of Medicine Jersey Shore University Medical Center Neptune NJ 5 Division of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundAlthough there has been a decrease in the incidence of ST?segment–elevation myocardial infarction (STEMI) in the United States, this trend might be stagnant or increasing in young women. We assessed the (...) (Journal of the American Heart Association)
11:13
Adverse Maternal and Infant Outcomes in Women With Chronic Hypertension in France (2010–2018): The Nationwide CONCEPTION Study - Grégory Lailler, Clémence Grave , Amélie Gabet , Nolwenn Regnault , Catherine Deneux?Tharaux , Sandrine Kretz , Claire Mounier?Vehier , Vassilis Tsatsaris , Geneviève Plu?Bureau , Jacques Blacher , and Valérie Olié 1 Santé publique France Saint?Maurice France 2 Department of Medicine Université Paris Est Créteil France 3 Obstetrical Perinatal and Pediatric Epidemiology Research Team (EPOPé), Centre for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), French National Institute for Health and Medical Research (INSERM) Paris France 4 Department of Medicine Université Paris Cité Paris France 5 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundIt has been suggested that chronic hypertension is a risk factor for negative maternal and fetal outcomes during pregnancy and postpartum. We aimed to estimate the association of chronic hypertension on (...) (Journal of the American Heart Association)
11:13
Sex?Related Differences in Clinical Outcomes After Thoracic Endovascular Aortic Repair - Sarah Yousef, James A. Brown , Edgar Aranda?Michel , Derek Serna?Gallegos , Yisi Wang , Takuya Ogami , and Ibrahim Sultan 1 Division of Cardiac Surgery, Department of Cardiothoracic Surgery University of Pittsburgh Pittsburgh PA 2 Department of Cardiothoracic Surgery University of Pittsburgh Medical Center Pittsburgh PA 3 Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundThoracic endovascular aortic repair (TEVAR) has been increasingly used for the treatment of descending thoracic aortic aneurysms and dissections. This study sought to evaluate the influence of sex on (...) (Journal of the American Heart Association)
11:27
JAHA Go Red for Women Spotlight 2023 - Mahasin S. Mujahid, and Pamela N. Peterson 1 Division of Epidemiology University of California Berkeley CA USA 2 Division of Cardiology, Department of Medicine University of Colorado Anschutz Medical Campus, Aurora and Denver Health Medical Center Denver CO USA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)

21 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:30
Correction to: One?Year Blood Pressure Trajectory After Acute Ischemic Stroke J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)
11:30
Correction to: Clinical Outcomes of Rhythm Control Strategies for Asymptomatic Atrial Fibrillation According to the Quality?of?Life Score: The CODE?AF (Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation) Registry J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)
11:30
Correction to: Left Ventricular Diastolic Dysfunction and Progression of Chronic Kidney Disease: Analysis of KNOW?CKD Data J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)
11:30
Examining the Real?Life Journey of Individuals and Families Affected by Single?Ventricle Congenital Heart Disease - Carlos M. Mery, Andrew Well , Kate Taylor , Kathleen Carberry , José Colucci , Christopher Ulack , Adam Zeiner , Michelle Mizrahi , Eileen Stewart , Christine Dillingham , Taylor Cook , Arotin Hartounian , Elizabeth McCullum , Jeremy T. Affolter , Heather Van Diest , Alexandra Lamari?Fisher , Stacey Chang , Scott Wallace , Elizabeth Teisberg , and Charles D. Fraser 1 Texas Center for Pediatric and Congenital Heart Disease UT Health Austin/Dell Children’s Medical Center Austin TX 2 Department of Surgery and Perioperative Care The University of Texas at Austin Dell Medical School Austin TX 3 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundThe lifetime journey of patients with single?ventricle congenital heart disease is characterized by long?term challenges that are incompletely understood and still unfolding. Health care redesign requires a (...) (Journal of the American Heart Association)
11:29
Relationship of Fibroblast Growth Factor 23 With Hospitalization for Heart Failure and Cardiovascular Outcomes in Patients Undergoing Cardiac Surgery - Felix Hofer, Andreas Hammer , Ulrike Pailer , Lorenz Koller , Niema Kazem , Eva Steinacher , Barbara Steinlechner , Martin Andreas , Günther Laufer , Johann Wojta , Thomas A. Zelniker , Christian Hengstenberg , Alexander Niessner , and Patrick Sulzgruber 1 Division of Cardiology, Department of Internal Medicine II Medical University of Vienna Vienna Austria 2 Vienna Health Care Group Vienna Austria 3 Department of Anesthesiology Medical University of Vienna Vienna Austria 4 Department of Cardiac Surgery Medical University of Vienna Vienna (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundFibroblast growth factor 23 (FGF?23) is crucial in regulating phosphate and vitamin D metabolism and is moreover associated with an increased cardiovascular risk. The specific objective of this study was to (...) (Journal of the American Heart Association)
11:29
Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE?IT - Brian Olshansky, Deepak L. Bhatt , Michael Miller , Ph. Gabriel Steg , Eliot A. Brinton , Terry A. Jacobson , Steven B. Ketchum , Ralph T. Doyle , Rebecca A. Juliano , Lixia Jiao , Peter R. Kowey , James A. Reiffel , Jean?Claude Tardif , Christie M. Ballantyne , Mina K. Chung , and 1 Department of Medicine University of Iowa Iowa City IA USA 2 Mount Sinai Heart Icahn School of Medicine at Mount Sinai Health System New York NY USA 3 Department of Medicine Crescenz Veterans Affairs Medical Center and Hospital of the University of Pennsylvania Philadelphia PA USA 4 French Alliance for (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundIn REDUCE?IT (Reduction of Cardiovascular Events With Icosapent Ethyl–Intervention Trial), icosapent ethyl (IPE) versus placebo) reduced cardiovascular death, myocardial infarction, stroke, coronary (...) (Journal of the American Heart Association)
11:29
Sex Differences in the Association Between Hypertension and Incident Atrial Fibrillation - Satoshi Kanazawa, Hidehiro Kaneko , Yuichiro Yano , Yuta Suzuki , Akira Okada , Satoshi Matsuoka , Katsuhito Fujiu , Nobuaki Michihata , Taisuke Jo , Norifumi Takeda , Hiroyuki Morita , Koichi Node , Hideo Yasunaga , and Issei Komuro 1 The Department of Cardiovascular Medicine The University of Tokyo Tokyo Japan 2 The Department of Advanced Cardiology The University of Tokyo Tokyo Japan 3 Department of Advanced Epidemiology, NCD Epidemiology Research Center Shiga University of Medical Science Shiga Japan 4 The Department of Family Medicine and Community Health Duke University Durham NC 5 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundLimited evidence is available on sex differences about the association between hypertension and incident atrial fibrillation (AF).Methods and ResultsWe used a nationwide health checkup and claims database to (...) (Journal of the American Heart Association)
11:29
SARC Gene Mutation Is Associated With Myocardial Fibrosis Measured by Histopathology and Cardiac Magnetic Resonance in Patients With Hypertrophic Cardiomyopathy - Manyun Huang, Jian Zhang , Changpeng Song , Shuiyun Wang , Zhou Zhou , Hongyue Wang , Shihua Zhao , Kunlun Yin , Li Li , Shujuan Yang , Xinxin Zheng , Jie Lu , and Xiaohong Huang 1 Department of Special Medical Treatment Center Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases of China, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China 2 Department of Cardiovascular Surgery Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases of China, Chinese (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundSarcomere gene mutation and myocardial fibrosis are both associated with poorer clinical outcomes in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to determine the relationship (...) (Journal of the American Heart Association)
11:28
Correction to: Antiatherosclerotic Effects of CSL112 Mediated by Enhanced Cholesterol Efflux Capacity J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. (Journal of the American Heart Association)
11:24
Racial, Ethnic, and Socioeconomic Inequities in Access to Left Atrial Appendage Occlusion - Kriyana P. Reddy, Lauren A. Eberly , Rim Halaby , Howard Julien , Sameed Ahmed M. Khatana , Elias J. Dayoub , Megan Coylewright , Mohamad Alkhouli , Paul N. Fiorilli , Taisei J. Kobayashi , David M. Goldberg , Pasquale Santangeli , Howard C. Herrmann , Jay Giri , Peter W. Groeneveld , Alexander C. Fanaroff , and Ashwin S. Nathan 1 Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center University of Pennsylvania Philadelphia PA 2 Division of Cardiology Hospital of the University of Pennsylvania Philadelphia PA 3 Leonard Davis Institute of Health Economics University of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundInequitable access to high?technology therapeutics may perpetuate inequities in care. We examined the characteristics of US hospitals that did and did not establish left atrial appendage occlusion (LAAO) (...) (Journal of the American Heart Association)
11:29
Association Between Triglycerides and Incident Cognitive Impairment in Black and White Adults in the Reasons for Geographic and Racial Differences in Stroke Study - Robert S. Rosenson, Mary Cushman , Emily C. McKinley , Paul Muntner , Zhixin Wang , Tomas Vaisar , Jay Heinecke , Christy Tangney , Suzanne Judd , and Lisandro D. Colantonio 1 Department of Cardiology Icahn School of Medicine at Mount Sinai New York NY 2 Department of Medicine University of Vermont Colchester VT 3 Department of Epidemiology, School of Public Health University of Alabama at Birmingham Birmingham AL 4 Department of Medicine University of Washington Seattle WA 5 Departments of Clinical Nutrition and Preventive Medicine Rush University and Medical Center Chicago (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundElevated nonfasting triglycerides were associated with non?Alzheimer dementia in a recent study. However, this study neither evaluated the association of fasting triglycerides with incident cognitive (...) (Journal of the American Heart Association)
11:28
Social Determinants, Cardiovascular Disease, and Health Care Cost: A Nationwide Study in the United States Using Machine Learning - Feinuo Sun, Jie Yao , Shichao Du , Feng Qian , Allison A. Appleton , Cui Tao , Hua Xu , Lei Liu , Qi Dai , Brian T. Joyce , Drew R. Nannini , Lifang Hou , and Kai Zhang 1 Global Aging and Community Initiative Mount Saint Vincent University Halifax Nova Scotia Canada 2 Department of Epidemiology and Biostatistics, School of Public Health University at Albany, State University of New York Albany NY 3 Department of Sociology University at Albany, State University of New York Albany NY 4 Department of Health Policy, Management and Behavior, School of Public Health University at Albany, State (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 5, March 7, 2023. BackgroundExisting studies on cardiovascular diseases (CVDs) often focus on individual?level behavioral risk factors, but research examining social determinants is limited. This study applies a novel machine learning (...) (Journal of the American Heart Association)

20 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:29
Role of PARP and TRPM2 in VEGF Inhibitor?Induced Vascular Dysfunction - Karla B. Neves, Rheure Alves?Lopes , Augusto C. Montezano , and Rhian M. Touyz 1 Institute of Cardiovascular and Medical Sciences University of Glasgow Glasgow United Kingdom 2 Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyde Glasgow United Kingdom 3 Research Institute of the McGill University Health Centre (RI?MUHC) McGill University Montreal Canada J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundHypertension and vascular toxicity are major unwanted side effects of antiangiogenic drugs, such as vascular endothelial growth factor inhibitors (VEGFis), which are effective anticancer drugs but have (...) (Journal of the American Heart Association)

15 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:51
Krüppel?Like Factors Orchestrate Endothelial Gene Expression Through Redundant and Non?Redundant Enhancer Networks - David R. Sweet, Roshan Padmanabhan , Xudong Liao , Himanshu R. Dashora , Xinmiao Tang , Lalitha Nayak , Rajan Jain , Sarah De Val , Vinesh Vinayachandran , and Mukesh K. Jain 1 Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center Cleveland OH 2 Department of Pathology Case Western Reserve University Cleveland OH 3 Division of Hematology and Oncology University Hospitals Cleveland Medical Center Cleveland OH 4 Department of Cell and Developmental Biology, Perelman School of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundProper function of endothelial cells is critical for vascular integrity and organismal survival. Studies over the past 2 decades have identified 2 members of the KLF (Krüppel?like factor) family of (...) (Journal of the American Heart Association)
11:39
Collagen?Specific HSP47+ Myofibroblasts and CD163+ Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS?CoV?2 Infections - Andrii Puzyrenko, Elizabeth R. Jacobs , Nathan Padilla , Adam Devine , Michael Aljadah , Benjamin N. Gantner , Amy Y. Pan , Shuping Lai , Qiang Dai , Jason C. Rubenstein , Paula E. North , Pippa M. Simpson , Rodney E. Willoughby , Caitlin C. O'Meara , Michael A. Flinn , John W. Lough , El?Sayed H. Ibrahim , Ze Zheng , Yunguang Sun , Juan Felix , Bryan C. Hunt , Gracious Ross , Hallgeir Rui , and Ivor J. Benjamin 1 Department of Pathology Medical College of Wisconsin Milwaukee WI 2 Department of Medicine Medical College of Wisconsin Milwaukee WI 3 Cardiovascular Center Medical College of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundCardiac fibrosis complicates SARS?CoV?2 infections and has been linked to arrhythmic complications in survivors. Accordingly, we sought evidence of increased HSP47 (heat shock protein 47), a (...) (Journal of the American Heart Association)
11:39
Therapeutic Hypothermia Inhibits Hypoxia?Induced Cardiomyocyte Apoptosis Via the MiR?483?3p/Cdk9 Axis - Qiqi Xue, Qianru Zhang , Zhenzhen Guo , Liping Wu , Yafen Chen , Zhongli Chen , Ke Yang , and Jiumei Cao 1 Department of Geriatrics Ruijin Hospital, Shanghai Jiaotong University School of Medicine Shanghai China 2 Department of Cardiovascular Medicine Ruijin Hospital, Shanghai Jiaotong University School of Medicine Shanghai China 3 Department of Cardiology Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine Shanghai China 4 Department of Cardiac Imaging Center The First Affiliated Hospital, Auhui Medical University Hefei China 5 Shanghai Institute of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundTherapeutic hypothermia has a beneficial effect on cardiac function after acute myocardial infarction, but the exact mechanism is still unclear. Recent research has suggested that microRNAs participate (...) (Journal of the American Heart Association)
11:38
Evaluating High?Confidence Genes in Conotruncal Cardiac Defects by Gene Burden Analyses - Martin M. C. Chui, Christopher C. Y. Mak , Mullin H. C. Yu , Sandra Y. Y. Wong , Kin?Shing Lun , Tak?Cheung Yung , Anna K. Y. Kwong , Pak?Cheong Chow , and Brian H. Y. Chung 1 Department of Paediatrics and Adolescent Medicine, School of Clinical Medicine, LKS Faculty of Medicine The University of Hong Kong Hong Kong SAR China 2 Department of Paediatrics and Adolescent Medicine The Hong Kong Children’s Hospital Hong Kong SAR China 3 Department of Paediatrics and Adolescent Medicine Queen Mary Hospital Hong Kong SAR (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundIn nonsyndromic conotruncal cardiac defects, the use of next?generation sequencing for clinical diagnosis is increasingly adopted, but gene?disease associations in research are only partially translated to (...) (Journal of the American Heart Association)
11:38
Liraglutide Accelerates Ischemia?Induced Angiogenesis in a Murine Diabetic Model - Yu?xin Zhu, Yi Li , Yu Ma , Xiao Zhang , Xingrong Du , Jiali Gao , Nian Hui Ding , Liqun Wang , Ni Chen , Mao Luo , Jianbo Wu , and Rong Li 1 Drug Discovery Research Center Southwest Medical University Luzhou Sichuan China 2 Department of Endocrinology The Affiliated Hospital of Southwest Medical University, Southwest Medical University Luzhou Sichuan China 3 Laboratory for Cardiovascular Pharmacology, Department of Pharmacology, School of Pharmacy Southwest Medical University Luzhou Sichuan China 4 Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundSevere hindlimb ischemia is a chronic disease with poor prognosis that can lead to amputation or even death. This study aimed to assess the therapeutic effect of liraglutide on hind?limb ischemia in type (...) (Journal of the American Heart Association)
11:38
Trends and Costs of US Telehealth Use Among Patients With Cardiovascular Disease Before and During the COVID?19 Pandemic - Jun Soo Lee, Kincaid Lowe Beasley , Michael W. Schooley , and Feijun Luo 1 Division for Heart Disease and Stroke Prevention Centers for Disease Control and Prevention Atlanta GA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe COVID?19 pandemic affected outpatient care delivery and patients' access to health care. However, no prior studies have documented telehealth use among patients with cardiovascular disease.Methods and (...) (Journal of the American Heart Association)
11:38
Markers of Kidney Tubular Function Deteriorate While Those of Kidney Tubule Health Improve in Primary Aldosteronism After Targeted Treatments - Vin?Cent Wu, Chieh?Kai Chan , Jeff S. Chueh , Yung?Ming Chen , Yen?Hung Lin , Chin?Chen Chang , Po?Chih Lin , Shiu?Dong Chung , and 1 Department of Internal Medicine National Taiwan University Hospital and College of Medicine, National Taiwan University Taipei Taiwan 2 TAIPAI, Taiwan Primary Aldosteronism Investigation (TAIPAI) Study Group Taipei Taiwan 3 Primary Aldosteronism Center at National Taiwan University Hospital (NTUH?PAC) Taipei Taiwan 4 Department of Internal Medicine National Taiwan University Hospital Hsin?Chu Branch Hsin?Chu County Taiwan 5 Department of Urology National (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundTargeted treatment with mineralocorticoid receptor antagonists (MRAs) or adrenalectomy in patients with primary aldosteronism (PA) causes a decline in estimated glomerular filtration rate; however, the (...) (Journal of the American Heart Association)
11:38
Cardiac Myocyte?Specific Overexpression of FASTKD1 Prevents Ventricular Rupture After Myocardial Infarction - Kurt D. Marshall, Paula J. Klutho , Lihui Song , Rajika Roy , Maike Krenz , and Christopher P. Baines 1 Department of Biomedical Sciences University of Missouri Columbia MO 2 Department of Medical Pharmacology and Physiology University of Missouri Columbia MO 3 Dalton Cardiovascular Research Center University of Missouri Columbia MO J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe mitochondrial mRNA?binding protein FASTKD1 (Fas?activated serine/threonine [FAST] kinase domain–containing protein 1) protects myocytes from oxidative stress in vitro. However, the role of FASTKD1 in (...) (Journal of the American Heart Association)
11:37
Impact of Concomitant Mitral Regurgitation on the Hemodynamic Indicators of Aortic Stenosis - Michael Šeman, Andrew F. Stephens , Antony Walton , Stephen J. Duffy , David McGiffin , Shane Nanayakkara , David M. Kaye , Shaun D. Gregory , and Dion Stub 1 School of Public Health and Preventative Medicine Monash University Melbourne Australia 2 Cardio?Respiratory Engineering and Technology Laboratory Baker Heart and Diabetes Institute Melbourne Australia 3 Department of Cardiology – Alfred Health Melbourne Australia 4 Department of Mechanical and Aerospace Engineering Monash University Melbourne Australia 5 Baker IDI Heart and Diabetes Institute and Alfred Hospital Melbourne Australia 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundIn patients with aortic stenosis (AS), the presence of mitral regurgitation (MR) can lead to underestimation of AS severity and worse clinical outcomes. The objective of this study was to characterize (...) (Journal of the American Heart Association)
11:37
Correction to: Racial and Ethnic Differences in the Association between Classical Cardiovascular Risk Factors and Common Carotid Intima?Media Thickness: An Individual Participant Data Meta?Analysis J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
11:37
Pediatric Extracorporeal Cardiopulmonary Resuscitation: Development of a Porcine Model and the Influence of Cardiopulmonary Resuscitation Duration on Brain Injury - Julia C. Slovis, Lindsay Volk , Constantine Mavroudis , Marco Hefti , William P. Landis , Anna L. Roberts , Nile Delso , Thomas Hallowell , Kathryn Graham , Jonathan Starr , Yuxi Lin , Richard Melchior , Vinay Nadkarni , Robert M. Sutton , Robert A. Berg , Sarah Piel , Ryan W. Morgan , and Todd J. Kilbaugh 1 Department of Anesthesiology and Critical Care Medicine Children’s Hospital of Philadelphia Philadelphia PA 2 Department of Surgery Robert Wood Johnson University Hospital New Brunswick NJ 3 Department of Surgery, Division of Cardiothoracic Surgery Children’s Hospital of Philadelphia (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe primary objective was to develop a porcine model of prolonged (30 or 60 minutes) pediatric cardiopulmonary resuscitation (CPR) followed by 22? to 24?hour survival with extracorporeal life support, and (...) (Journal of the American Heart Association)
11:37
Influence of the Social Environment on Ideal Cardiovascular Health - Sarah S. Singh, Saverio Stranges , Piotr Wilk , Anthony S. L. Tang , and Stephanie J. Frisbee 1 Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry University of Western Ontario London Ontario Canada 2 Department of Medicine, Schulich School of Medicine & Dentistry University of Western Ontario London Ontario Canada 3 Department of Family Medicine, Schulich School of Medicine & Dentistry University of Western Ontario London Ontario Canada 4 Department of Precision Medicine Luxembourg Institute of Health Strassen Luxembourg 5 Department of Paediatrics, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe environment plays a large role in the health of individuals; however, more research is needed to better understand aspects of the environment that most influence health. Specifically, our study (...) (Journal of the American Heart Association)
11:37
Correction to: Endothelial Foxp1 Regulates Neointimal Hyperplasia Via Matrix Metalloproteinase?9/Cyclin Dependent Kinase Inhibitor 1B Signal Pathway J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
11:37
Premature Ventricular Contractions and Atrial Fibrillation: The Reunion of Distant Relatives? - Anne?Sophie Lacharite?Roberge, and Kurt S. Hoffmayer 1 University of California San Diego Division of Cardiology, Department of Medicine, Section of Cardiac Electrophysiology San Diego CA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
11:36
Watchman FLX's Sophomore Year Report Card - Thomas A. Dewland 1 Section of Electrophysiology, Division of Cardiology, Department of Internal Medicine University of California San Francisco CA USA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
11:36
Right Ventricular Function During Exercise After Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension - Natalia J. Braams, Azar Kianzad , Lilian J. Meijboom , Jesper Westenberg , Onno A. Spruijt , Josien Smits , Anton Vonk Noordegraaf , Anco Boonstra , Esther J. Nossent , Frank Oosterveer , M. Louis Handoko , Petr Symersky , Frances S. de Man , and Harm Jan Bogaard 1 Department of Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands 2 Department of Radiology and Nuclear Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands 3 Department of Cardiology, Amsterdam (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundPulmonary endarterectomy (PEA) for chronic thromboembolic pulmonary hypertension improves resting hemodynamics and right ventricular (RV) function. Because exercise tolerance frequently remains impaired, (...) (Journal of the American Heart Association)
11:36
Clinical Characteristics and Outcomes Among People Living With HIV Undergoing Percutaneous Coronary Intervention: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program - Rushi V. Parikh, Annika Hebbe , Anna E. Barón , Gary K. Grunwald , Mary E. Plomondon , Jonathan Gordin , Robert W. Yeh , Hani Jneid , Rajesh V. Swaminathan , Stephen W. Waldo , Alexander Monto , Eric Secemsky , and Priscilla Y. Hsue 1 Division of Cardiology University of California, Los Angeles Los Angeles CA USA 2 Rocky Mountain Regional Veterans Affairs Medical Center Aurora CO USA 3 CART Program, Office of Quality and Patient Safety Veterans Health Administration Washington DC USA 4 Department of Biostatistics and Informatics University of Colorado Aurora CO USA 5 Smith Center for (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundClinical characteristics and outcomes in people living with HIV (PLWH) undergoing percutaneous coronary intervention (PCI) remain poorly described. We sought to compare real?world treatment of coronary (...) (Journal of the American Heart Association)
11:36
Impact of Reperfusion on Temporal Immune Cell Dynamics After Myocardial Infarction - Richard Ying Ke Zhang, Blake J. Cochran , Shane R. Thomas , and Kerry?Anne Rye 1 School of Medical Sciences University of New South Wales Sydney New South Wales J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. Excessive inflammation and impaired healing of cardiac tissue following a myocardial infarction (MI) can drive the development of heart failure. Cardiac repair begins immediately after the onset of MI and (...) (Journal of the American Heart Association)
11:36
High Burden of Premature Ventricular Complex Increases the Risk of New?Onset Atrial Fibrillation - Po?Tseng Lee, Mu?Hsian Huang , Ting?Chung Huang , Chi?Hui Hsu , Sheng?Hsian Lin , and Ping?Yen Liu 1 Institute of Clinical Medicine, College of Medicine, National Cheng Kung University Tainan Taiwan 2 Division of Cardiology, Department of Internal Medicine National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan 3 Department of Statistics, National Cheng Kung University Tainan Taiwan 4 Biostatistics Consulting Center National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University Tainan Taiwan 5 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundHigh burden of premature ventricular complex (PVC) leads to increased cardiovascular mortality. A recent nationwide population?based study demonstrated that PVC is associated with an increased risk of (...) (Journal of the American Heart Association)
11:35
Two?Year Outcomes With a Next?Generation Left Atrial Appendage Device: Final Results of the PINNACLE FLX Trial - Shephal K. Doshi, Saibal Kar , Ashish Sadhu , Rodney Horton , Jose Osorio , Christopher Ellis , James Stone , Manish Shah , Srinivas R. Dukkipati , Stuart Adler , Devi G. Nair , Jamie Kim , Oussama Wazni , Matthew J. Price , David R. Holmes , Robert Shipley , Thomas Christen , Dominic J. Allocco , Vivek Y. Reddy 1 Providence, Saint Johns Health Center Pacific Heart Institute Santa Monica CA 2 Los Robles Regional Medical Center Thousand Oaks CA 3 Phoenix Cardiovascular Research Group Phoenix AZ 4 Texas Cardiac Arrhythmia Austin TX 5 Arrhythmia Institute at Grandview Birmingham AL 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe PINNACLE FLX (Protection Against Embolism for Non?valvular AF [Atrial Fibrillation] Patients: Investigational Device Evaluation of the Watchman FLX LAA [Left Atrial Appendage] Closure Technology) (...) (Journal of the American Heart Association)
11:33
Sleep Irregularity and Subclinical Markers of Cardiovascular Disease: The Multi?Ethnic Study of Atherosclerosis - Kelsie M. Full, Tianyi Huang , Neomi A. Shah , Matthew A. Allison , Erin D. Michos , Daniel A. Duprez , Susan Redline , and Pamela L. Lutsey 1 Division of Epidemiology and Community Health University of Minnesota School of Public Health Minneapolis MN 2 Channing Division of Network Medicine, Brigham and Women’s Hospital Harvard University Boston MA 3 Division of Sleep Medicine Harvard Medical School Boston MA 4 Division of Pulmonary, Critical Care and Sleep Medicine Icahn School of Medicine at Mount Sinai New York NY 5 Division of Preventive Medicine University of California San Diego San (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundSleep irregularity has been linked to incident cardiovascular disease. Less is known about associations of sleep regularity with atherosclerosis. We examined cross?sectional associations of (...) (Journal of the American Heart Association)

8 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:16
Impact of Peripheral Artery Disease in Patients With Heart Failure Undergoing Transcatheter Mitral Valve Repair: The COAPT Trial - Bahira Shahim, David J. Cohen , Ori Ben?Yehuda , Björn Redfors , Saibal Kar , D. Scott Lim , Suzanne V. Arnold , Yanru Li , JoAnn Lindenfeld , William T. Abraham , Michael J. Mack , and Gregg W. Stone 1 Clinical Trials Center Cardiovascular Research Foundation New York NY 2 Division of Cardiology, Department of Medicine Solna Karolinska Institutet, Karolinska University Hospital Stockholm Sweden 3 St. Francis Hospital Roslyn NY 4 New York?Presbyterian Hospital/Columbia University Irving Medical Center NY New York 5 Division of Cardiology University of California ? San Diego San Diego CA 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundPeripheral artery disease (PAD) and heart failure (HF) often coexist. Whether PAD influences outcomes of transcatheter mitral valve repair (TMVr) in patients with HF and severe secondary mitral (...) (Journal of the American Heart Association)
12:15
Association Between Measures of Body Composition and Coronary Calcium: Findings From the Multi?Ethnic Study of Atherosclerosis - Tamara Horwich, Preethi Srikanthan , Anisha Gaitonde , Karol Watson , Matthew Allison , and Richard Kronmal 1 Division of Cardiology David Geffen School of Medicine at University of California Los Angeles Los Angeles CA 2 Department of Family Medicine and Public Health University of California San Diego La Jolla CA 3 Department of Biostatistics University of Washington Seattle WA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundObesity, as measured by body mass index, is widely recognized as a risk factor for the development of cardiovascular disease. However, the role of body composition components such as fat and lean mass is (...) (Journal of the American Heart Association)
12:15
Percutaneous MitraClip Device or Surgical Mitral Valve Repair in Patients With Primary Mitral Regurgitation Who Are Candidates for Surgery: Design and Rationale of the REPAIR MR Trial - Patrick M. McCarthy, Brian Whisenant , Anita W. Asgar , Gorav Ailawadi , James Hermiller , Mathew Williams , Andrew Morse , Michael Rinaldi , Paul Grayburn , James D. Thomas , Randolph Martin , Federico M. Asch , Yu Shu , Kartik Sundareswaran , Neil Moat , and Saibal Kar 1 Northwestern Medicine Chicago IL 2 Intermountain Healthcare Murray UT 3 Montreal Heart Institute Montreal QC Canada 4 University of Michigan Hospital Ann Arbor MI 5 St. Vincent’s Hospital Indianapolis IN 6 New York University Medical Center New York NY 7 St. Thomas Hospital Nashville TN 8 Sanger Heart and Vascular (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe current standard of care for the treatment of patients with primary mitral regurgitation (MR) is surgical mitral valve repair. Transcatheter edge?to?edge repair with the MitraClip device provides a (...) (Journal of the American Heart Association)
12:14
Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2?Hit” Murine Model - Kyle B. LaPenna, Zhen Li , Jake E. Doiron , Thomas E. Sharp , Huijing Xia , Karl Moles , Kashyap Koul , John S. Wang , David J. Polhemus , Traci T. Goodchild , Ravi B. Patel , Sanjiv J. Shah , and David J. Lefer 1 Cardiovascular Center of Excellence Louisiana State University Health Sciences Center New Orleans LA 2 Department of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center New Orleans LA 3 Department of Medicine, Section of Cardiology Louisiana State University Health Sciences Center New Orleans LA 4 Department of Medicine Johns Hopkins (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundRecent studies have suggested that cardiac nitrosative stress mediated by pathological overproduction of nitric oxide (NO) via inducible NO synthase (iNOS) contributes to the pathogenesis of heart (...) (Journal of the American Heart Association)
12:14
Obesity and Overweight: Probing Causes, Consequences, and Novel Therapeutic Approaches Through the American Heart Association's Strategically Focused Research Network - Jeanne M. Clark, W. Timothy Garvey , Kevin D. Niswender , Ann Marie Schmidt , Rexford S. Ahima , Jose O. Aleman , Ashley N. Battarbee , Joshua Beckman , Wendy L. Bennett , Nancy J. Brown , Paula Chandler?Laney , Nancy Cox , Ira J. Goldberg , Kirk M. Habegger , Lorie M. Harper , Alyssa H. Hasty , Bertha A. Hidalgo , Sangwon F. Kim , Julie L. Locher , James M. Luther , Nisa M. Maruthur , Edgar R. Miller , Mary Ann Sevick , and Quinn Wells 1 Division of General Internal Medicine, Department of Medicine The Johns Hopkins University School of Medicine Baltimore MD 2 Department of Epidemiology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. ABSTRACT: As the worldwide prevalence of overweight and obesity continues to rise, so too does the urgency to fully understand mediating mechanisms, to discover new targets for safe and effective therapeutic (...) (Journal of the American Heart Association)
12:14
Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model - Catherine Lapointe, Laurence Vincent , Hugo Giguère , Mannix Auger?Messier , Adel Schwertani , Denan Jin , Shinji Takai , Gunnar Pejler , Martin G. Sirois , Hanna Tinel , Stefan Heitmeier , and Pedro D'Orléans?Juste 1 Department of Pharmacology and Physiology and Faculté de Médecine et des Sciences de la Santé Université de Sherbrooke Sherbrooke QC Canada 2 Department of Medicine, Service of Cardiology, Faculté de Médecine et des Sciences de la Santé Université de Sherbrooke Sherbrooke QC Canada 3 Department of Medicine McGill University Montréal QC Canada 4 Department of Innovative Medicine Osaka (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundDeep vein thrombosis (DVT) is the primary cause of pulmonary embolism and the third most life?threatening cardiovascular disease in North America. Post?DVT anticoagulants, such as warfarin, heparin, and (...) (Journal of the American Heart Association)
12:14
Host?Microbiota Communication in Spontaneously Hypertensive Rats Generates Unique IgA?Coated Gut Microbes - Jing Li, Elaine M. Richards , Ramakumar Tummala , Carl J. Pepine , Mohan K. Raizada , and Tao Yang 1 Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden Chinese Academy of Sciences Wuhan Hubei China 2 Department of Physiology and Functional Genomics University of Florida College of Medicine Gainesville FL USA 3 Department of Physiology and Pharmacology Center for Hypertension and Precision Medicine College of Medicine and Life Sciences University of Toledo OH USA 4 Division of Cardiovascular Medicine Department of Medicine University of Florida (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundHypertension is associated with gut dysbiosis, altered intestinal immunity, and gut pathology in animal models and humans. Although these findings have implicated impaired interactions between gut and (...) (Journal of the American Heart Association)
12:13
Associations of Serum Carotenoids With Risk of All?Cause and Cardiovascular Mortality in Hypertensive Adults - Xu Zhu, Iokfai Cheang , Yuan Tang , Mengsha Shi , Qingqing Zhu , Rongrong Gao , Shengen Liao , Wenming Yao , Yanli Zhou , Haifeng Zhang , and Xinli Li 1 Department of Cardiology The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital Nanjing China 2 Department of Cardiology The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School Suzhou China J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundSystemic oxidative stress is involved in the development of hypertension, whereas carotenoids are a group of natural antioxidants. Our study aims to evaluate the relationships between the serum (...) (Journal of the American Heart Association)
12:13
Correction to: Cryoballoon Ablation for the Treatment of Atrial Fibrillation in Patients with Concomitant Heart Failure and either Reduced or Preserved Left Ventricular Ejection Fraction: Results from the Cryo AF Global Registry J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
12:13
Informing Use of Telehealth for Managing Chronic Conditions: Mixed?Methods Evaluation of Telehealth Use to Manage Heart Failure During COVID?19 - Chelsea Leonard, Wenhui Liu , Ariel Holstein , Slande Alliance , Mary Nunnery , Carly Rohs , Marilyn Sloan , and David E. Winchester 1 Denver Seattle Center of Innovation (COIN) Aurora Colorado 2 Division of Health Care Policy and Research University of Colorado Medical Campus Aurora Colorado 3 Malcom Randall VA Medical Center Gainesville Florida J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundThe COVID?19 pandemic forced Veterans Health Administration facilities to rapidly adopt and deploy telehealth alternatives to provide continuity of care to veterans while minimizing physical contact. The (...) (Journal of the American Heart Association)
12:13
Prevention and Management of Stroke After Transcatheter Aortic Valve Replacement: The Mount Sinai Stroke Initiative - Sahil Khera, Anoop N. Koshy , Gilbert H. L. Tang , Pedro Moreno , Roxana Mehran , George D. Dangas , David Bronster , Annapoorna S. Kini , Michael Fara , and Samin K. Sharma 1 Division of Interventional Cardiology Mount Sinai Hospital New York NY 2 Department of Cardiovascular Surgery Mount Sinai Hospital New York NY 3 Division of Neurology Mount Sinai Hospital New York NY J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
12:12
CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells - Guoshuai Feng, Cuige Zhu , Chieh?Yu Lin , Andrea Bredemeyer , Irmgard Förster , Daniel Kreisel , and Kory J. Lavine 1 Cardiovascular Division, Department of Medicine Washington University School of Medicine St. Louis MO 2 Division of Oncology Washington University School of Medicine St. Louis MO 3 Department of Pathology and Immunology Washington University St. Louis MO 4 Immunology and Environment, LIMES Institute University of Bonn Germany 5 Department of Surgery Washington University St. Louis MO 6 Department of Developmental Biology Washington University St. Louis (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundViral myocarditis is characterized by leukocyte infiltration of the heart and cardiomyocyte death. We recently identified C?C chemokine ligand (CCL) 17 as a proinflammatory effector of C?C chemokine (...) (Journal of the American Heart Association)
12:15
Brain?Derived Neurotrophic Factor Precursor Contributes to a Proinflammatory Program in Monocytes/Macrophages After Acute Myocardial Infarction - Jia?Nan Li, Ru?Yi Luo , Cong Luo , Zhao?Lan Hu , An?Hui Zha , Wei?Yun Shen , Qiao Li , Hui Li , Di Fu , and Ru?Ping Dai 1 Department of Anesthesiology The Second Xiangya Hospital, Central South University Changsha China 2 Anesthesia Medical Research Center Central South University Changsha China 3 Department of Anesthesiology Xiangya Hospital, Central South University Changsha China J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe imbalance of monocyte/macrophage polarization toward the preferential proinflammatory phenotype and a lack of normal inflammation resolution are present in acute myocardial infarction (AMI). Our previous study showed that (...) (Journal of the American Heart Association)

7 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:41
Randomized Clinical Trial to Evaluate an Atrial Fibrillation Stroke Prevention Shared Decision?Making Pathway - Paul J. Wang, Ying Lu , Kenneth W. Mahaffey , Amy Lin , Daniel P. Morin , Samuel F. Sears , Mina K. Chung , Andrea M. Russo , Bryant Lin , Jonathan Piccini , Mellanie True Hills , Caroline Berube , Krishna Pundi , Tina Baykaner , Gotzone Garay , Karma Lhamo , Eli Rice , Idean A. Pourshams , Rushil Shah , Paul Newswanger , Katie DeSutter , Julio Cesar Nunes , Michelle A. Albert , Kevin A. Schulman , Paul A. Heidenreich , T. Jared Bunch , Lee M. Sanders , Mintu Turakhia , Abraham Verghese , and Randall S. Stafford 1 Stanford University Department of Medicine Palo Alto CA 2 Stanford (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundOral anticoagulation reduces stroke and disability in atrial fibrillation (AF) but is underused. We evaluated the effects of a novel patient?clinician shared decision?making (SDM) tool in reducing oral (...) (Journal of the American Heart Association)

6 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:01
Application of Magnetocardiography to Screen for Inflammatory Cardiomyopathy and Monitor Treatment Response - Debora Brala, Tharusan Thevathasan , Simon Grahl , Steve Barrow , Michele Violano , Hendrikje Bergs , Ainoosh Golpour , Phillip Suwalski , Wolfgang Poller , Carsten Skurk , Ulf Landmesser , and Bettina Heidecker 1 Charité–Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt–Universität zu Berlin Berlin Germany 2 Division of Instrumentation at Space Telescope Science Institute Baltimore MD 3 Berlin Institute of Health at Charité Berlin (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. BackgroundInflammatory cardiomyopathy is one of the most common causes of sudden cardiac death in young adults. Diagnosis of inflammatory cardiomyopathy remains challenging, and better monitoring tools are needed. (...) (Journal of the American Heart Association)

3 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:03
Medication Adherence—Still the Holy Grail - Rhonda M. Cooper?DeHoff, and Steven M. Smith 1 University of Florida, College of Pharmacy and College of Medicine Gainesville FL J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
13:03
Fixed?Dose Combination Medication Use Among US Adults With Hypertension: A Missed Opportunity - Claire M. Mobley, Alexis S. Bryan , Andrew E. Moran , Catherine G. Derington , Yiyi Zhang , and Brandon K. Bellows 1 Columbia University New York NY 2 University of Utah Salt Lake City UT J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 4, February 21, 2023. (Journal of the American Heart Association)
12:30
New Cerebral Microbleeds After Catheter?Based Structural Heart Interventions: An Exploratory Analysis - Tim Bastian Braemswig, Madeleine Kusserow , Barbara Bellmann , Frederik Beckhoff , Markus Reinthaler , Regina von Rennenberg , Hebun Erdur , Jan F. Scheitz , Ivana Galinovic , Kersten Villringer , David M. Leistner , Heinrich J. Audebert , Matthias Endres , Ulf Landmesser , Karl Georg Haeusler , Jochen B. Fiebach , Alexander Lauten , Andreas Rillig , and Christian H. Nolte 1 Klinik und Hochschulambulanz für Neurologie Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt?Universität zu Berlin Berlin Germany 2 Berlin Institute of Health (BIH) at Charité (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundCerebral microbleeds (CMBs) are increasingly recognized as “covert” brain lesions indicating increased risk of future neurological events. However, data on CMBs in patients undergoing catheter?based (...) (Journal of the American Heart Association)
12:29
Biomechanical and Mechanobiological Drivers of the Transition From PostCapillary Pulmonary Hypertension to Combined Pre?/PostCapillary Pulmonary Hypertension - Betty J. Allen, Hailey Frye , Rasika Ramanathan , Laura R. Caggiano , Diana M. Tabima , Naomi C. Chesler , and Jennifer L. Philip 1 Department of Surgery University of Wisconsin?Madison Madison WI 2 Department of Biomedical Engineering University of Wisconsin?Madison Madison WI 3 Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center and Department of Biomedical Engineering University of California Irvine CA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. Combined pre?/postcapillary pulmonary hypertension (Cpc?PH), a complication of left heart failure, is associated with higher mortality rates than isolated postcapillary pulmonary hypertension alone. Currently, (...) (Journal of the American Heart Association)
12:29
Clinical Outcome of Revascularization Deferral With Instantaneous Wave?Free Ratio and Fractional Flow Reserve: A 5?Year Follow?Up Substudy From the iFR?SWEDEHEART Trial - Karolina Berntorp, Rebecca Rylance , Troels Yndigegn , Sasha Koul , Ole Fröbert , Evald H. Christiansen , David Erlinge , and Matthias Götberg 1 Department of Cardiology Skåne University Hospital, Clinical Sciences, Lund University Lund Sweden 2 Faculty of Health, Department of Cardiology Örebro University Hospital Örebro Sweden 3 Department of Cardiology Aarhus University Hospital Skejby Denmark J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundAlthough physiology?based assessment of coronary artery stenosis using instantaneous wave?free ratio (iFR) and fractional flow reserve (FFR) are established methods of guiding coronary revascularization, (...) (Journal of the American Heart Association)
12:29
High?Mobility Group Box 1–Signaling Inhibition With Glycyrrhizin Prevents Cerebral T?Cell Infiltration After Cardiac Arrest - Emilie Boissady, Yara Abi Zeid Daou , Estelle Faucher , Matthias Kohlhauer , Fanny Lidouren , Cynthia El Hedjaj , Sophie Chateau?Joubert , Hakim Hocini , Sophie Hue , Bijan Ghaleh , and Renaud Tissier 1 Université Paris Est?Créteil, INSERM, IMRB Créteil France 2 Ecole Nationale Vétérinaire d’Alfort, IMRB, After ROSC Network Maisons?Alfort France 3 Vaccine Research Institute Université Paris Est?Créteil Créteil France J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundHigh?mobility group box 1 (HMGB1) is a major promotor of ischemic injuries and aseptic inflammatory responses. We tested its inhibition on neurological outcome and systemic immune response after cardiac (...) (Journal of the American Heart Association)
12:28
Impact of Impella RP Versus Vasoactive Treatment on Right and Left Ventricular Strain in a Porcine Model of Acute Cardiogenic Shock Induced by Right Coronary Artery Embolization - Peter H. Frederiksen, Jakob Josiassen , Nanna L. J. Udesen , Louise Linde , Ole K. Helgestad , Ann Banke , Lisette O. Jensen , Henrik Schmidt , Christian Hassager , Hanne B. Ravn , and Jacob E. Møller 1 Department of Cardiology Odense University Hospital Odense Denmark 2 Faculty of Health Sciences University of Southern Denmark Odense Denmark 3 Department of Cardiology, Heart Center Copenhagen University Hospital Rigshospitalet Copenhagen Denmark 4 Department of Cardiothoracic Anaesthesiology Odense University Hospital Odense (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundThe response of the left ventricle to cardiogenic shock (CS) caused by right ventricular (RV) infarction and the effect of treatment with either vasoactive treatment or Impella RP are not well described. (...) (Journal of the American Heart Association)
12:28
GLP?1 Promotes Cortical and Medullary Perfusion in the Human Kidney and Maintains Renal Oxygenation During NaCl Loading - Bryan Haddock, Kasper B. Kristensen , Mahvish Tayyab , Henrik B. W. Larsson , Ulrich Lindberg , Mark Vestergaard , Susan Francis , Boye L. Jensen , Ulrik B. Andersen , and Ali Asmar 1 Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet Copenhagen University Hospital Copenhagen Denmark 2 Sir Peter Mansfield Magnetic Resonance Centre School of Physics and Astronomy University of Nottingham United Kingdom 3 Department of Cardiovascular and Renal Research, Institute of Molecular Medicine University of Southern Denmark Odense Denmark 4 Department of Clinical Physiology and (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundGLP?1 (glucagon?like peptide?1) receptor agonists exert beneficial long?term effects on cardiovascular and renal outcomes. In humans, the natriuretic effect of GLP?1 depends on GLP?1 receptor interaction, is (...) (Journal of the American Heart Association)
12:28
Virtual Outpatient Visits During COVID?19 Pandemic: So Distant, Yet So Close - Giuseppe Ambrosio, Gian Franco Gensini , and Fabrizio Stracci 1 Division of Cardiology, and Center for Clinical and Translational Research (CERICLET) University of Perugia School of Medicine Perugia Italy 2 Scientific Direction IRCCS MultiMedica Milan Italy 3 Section of Public Health, and Center for Clinical and Translational Research (CERICLET) University of Perugia School of Medicine Perugia Italy J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. (Journal of the American Heart Association)
12:28
Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension in Patients With Chronic Obstructive Pulmonary Disease: A Note of Caution - Richard Cheng, and Miles Conrad 1 Division of Cardiology, Department of Internal Medicine Advanced Heart Failure Comprehensive Care Center, University of California San Francisco CA USA 2 Section of Interventional Radiology, Department of Radiology University of California San Francisco CA USA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. (Journal of the American Heart Association)
12:28
Left Ventricular Assist Devices and Renal Ramifications - Ajith Nair, and Harveen Lamba 1 Division of Cardiology, Department of Medicine, Baylor College of Medicine Houston TX 2 Division of Cardiothoracic Transplantation and Circulatory Support, Department of Surgery, Baylor College of Medicine Houston TX J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. (Journal of the American Heart Association)
12:27
Efficacy and Safety of Balloon Pulmonary Angioplasty for Patients With Chronic Thromboembolic Pulmonary Hypertension and Comorbid Chronic Obstructive Pulmonary Disease - Hiroyuki Fujii, Yu Taniguchi , Sachiyo Yoneda , Keisuke Miwa , Yoichiro Matsuoka , Kenichi Yanaka , Yasunori Tsuboi , Noriaki Emoto , and Kenichi Hirata 1 Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundBalloon pulmonary angioplasty (BPA) is a promising treatment modality for nonoperable chronic thromboembolic pulmonary hypertension (CTEPH). However, BPA for atypical CTEPH with concurrent chronic (...) (Journal of the American Heart Association)
12:27
Frequency and Type of Outpatient Visits for Patients With Cardiovascular Ambulatory?Care Sensitive Conditions During the COVID?19 Pandemic and Subsequent Outcomes: A Retrospective Cohort Study - Finlay A. McAlister, Zoe Hsu , Yuan Dong , Ross T. Tsuyuki , Carl van Walraven , and Jeffrey A. Bakal 1 Division of General Internal Medicine, Faculty of Medicine and Dentistry University of Alberta Edmonton Alberta Canada 2 Alberta Strategy for Patient Oriented Research Support Unit Edmonton Alberta Canada 3 Departments of Pharmacology, Medicine, and EPICORE Centre, Faculty of Medicine and Dentistry University of Alberta Edmonton Alberta Canada 4 Division of General Internal Medicine Ottawa Hospital and the Ottawa Health Research Institute Ottawa Ontario Canada 5 Provincial Research Data (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundBecause the impact of changes in how outpatient care was delivered during the COVID?19 pandemic is uncertain, we designed this study to examine the frequency and type of outpatient visits between March 1, (...) (Journal of the American Heart Association)
12:27
Fifty Years of Global Cardiovascular Research in Africa: A Scientometric Analysis, 1971 to 2021 - Jean Jacques Noubiap, Dominic Millenaar , Dike Ojji , Q. Eileen Wafford , Christian Ukena , Michael Böhm , Karen Sliwa , Mark D. Huffman , and Felix Mahfoud 1 Cameroon Ministry of Public Health Yaoundé Cameroon 2 Centre for Heart Rhythm Disorders The University of Adelaide Adelaide Australia 3 Department of Internal Medicine III, Cardiology, Angiology, Intensive Care Medicine Saarland University Hospital Homburg Germany 4 Department of Medicine, Faculty of Clinical Sciences University of Abuja, and University of Abuja Teaching Hospital Gwagwalada Nigeria 5 Galter Health Sciences Library and (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundTo analyze the quantity and impact of cardiovascular research done in Africa or coauthored by researchers based in Africa, their determinants, and the patterns of research collaboration.Methods and (...) (Journal of the American Heart Association)
12:27
Long?Term Changes in Estimated Glomerular Filtration Rate in Left Ventricular Assist Device Recipients: A Longitudinal Joint Model Analysis - Bethany Roehm, Susan Hedayati , Amanda R. Vest , Gaurav Gulati , Jonathan Miao , Hocine Tighiouart , Daniel E. Weiner , and Lesley A. Inker 1 Division of Nephrology University of Texas Southwestern Medical Center Dallas TX 2 Division of Cardiology Tufts Medical Center Boston MA 3 Division of Nephrology Tufts Medical Center Boston MA 4 Tufts Medical Center Institute for Clinical Research and Health Policy Studies Boston MA 5 Tufts University, Tufts Clinical and Translational Science Institute Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundAdvanced kidney disease is often a relative contraindication to left ventricular assist device (LVAD) implantation because of concerns for poor outcomes including worsening kidney disease. Data are (...) (Journal of the American Heart Association)

1 February

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:48
Describing Sepsis as a Risk Factor for Cardiovascular Disease - Gabriel Wardi, Alex Pearce , Anthony DeMaria , and Atul Malhotra 1 Department of Emergency Medicine University of California at San Diego La Jolla CA USA 2 Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine University of California at San Diego La Jolla CA USA 3 Division of Cardiovascular Medicine, Department of Internal Medicine University of California at San Diego La Jolla CA USA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. (Journal of the American Heart Association)
11:48
Cardiovascular Events Among Survivors of Sepsis Hospitalization: A Retrospective Cohort Analysis - Jacob C. Jentzer, Patrick R. Lawler , Holly K. Van Houten , Xiaoxi Yao , Kianoush B. Kashani , and Shannon M. Dunlay 1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN 2 Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic Rochester MN 3 Peter Munk Cardiac Centre, University Health Network Toronto Ontario Canada 4 Interdepartmental Division of Critical Care Medicine and Division of Cardiology University of Toronto Toronto Ontario Canada 5 Division of Pulmonary and Critical Care Medicine Mayo Clinic Rochester MN 6 Division of Nephrology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundSepsis is associated with an elevated risk of late cardiovascular events among hospital survivors.Methods and ResultsWe included OptumLabs Data Warehouse patients from 2009 to 2019 who survived a (...) (Journal of the American Heart Association)

31 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:12
Genetic Variants Associated With Systolic Blood Pressure in Children and Adolescents - Mindy M. Pike, Jonathan Schildcrout , Scott Baldwin , Todd Edwards , Loren Lipworth , and Cassianne Robinson?Cohen 1 Division of Epidemiology, Department of Medicine Vanderbilt University Medical Center Nashville TN USA 2 Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA 3 Division of Pediatric Cardiology, Department of Medicine Vanderbilt University Medical Center Nashville TN USA 4 Division of Nephrology, Department of Medicine Vanderbilt University Medical Center Nashville TN USA 5 Vanderbilt?O’Brien Center for Kidney Disease Vanderbilt University Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundGenetics, along with lifestyle and behavioral characteristics, play an important role in hypertension in adults. Our aim was to identify genetic variants associated with blood pressure in childhood and (...) (Journal of the American Heart Association)
12:12
Analysis of Coronary Arterial Aneurysm Regression in Patients With Kawasaki Disease by Aneurysm Severity: Factors Associated With Regression - Taichi Kato, Masaru Miura , Tohru Kobayashi , Tetsuji Kaneko , Naoya Fukushima , Kenji Suda , Jun Maeda , Shinya Shimoyama , Junko Shiono , Keiichi Hirono , Kazuyuki Ikeda , Seiichi Sato , Fujito Numano , Yoshihide Mitani , Kenji Waki , Mamoru Ayusawa , Ryuji Fukazawa , Shigeto Fuse 1 Department of Pediatrics Nagoya University Graduate School of Medicine Nagoya Aichi Japan 2 Department of Cardiology Tokyo Metropolitan Children’s Medical Center Tokyo Japan 3 Department of Data Science Clinical Research Center National Center for Child Health and Development Tokyo Japan 4 Clinical Research (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundCoronary arterial aneurysms (CAAs) associated with Kawasaki disease (KD) significantly affect prognosis. However, the clinical course of CAAs and factors associated with CAA regression have not been well (...) (Journal of the American Heart Association)
12:11
Predictors of Improvement in Exercise Tolerance After Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension - Kyohei Daigo, Yoshinori Katsumata , Kosho Esaki , Yuji Iwasawa , Genki Ichihara , Kotaro Miura , Kohsuke Shirakawa , Yasunori Sato , Kazuki Sato , and Keiichi Fukuda 1 Department of Cardiology Keio University School of Medicine Tokyo Japan 2 Department of Preventive Medicine and Public Health Keio University School of Medicine Tokyo Japan 3 Institute for Integrated Sports Medicine, Keio University School of Medicine Tokyo Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundBalloon pulmonary angioplasty (BPA) improves exercise tolerance and hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension. However, it is still unclear which patient (...) (Journal of the American Heart Association)
12:11
Patient?Centered Insights and Biases Regarding Cardiologists Via Online Review Platform Analysis - Erica Mark, Mackenzi Oswald , Priyanka Kundar , and Martha Gulati 1 School of Medicine University of Virginia Charlottesville VA 2 Barbra Streisand Women’s Heart Center Smidt Heart Institute, Cedars?Sinai Medical Center Los Angeles CA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundOnline cardiologist reviews, such as those on the Yelp website, are a frequently used method for patients to find a cardiologist. It remains unknown how bias may influence such reviews. Our objectives for (...) (Journal of the American Heart Association)
12:10
Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin?Deficient Mice via Upregulation of Angiotensin (1–7) - Kohei Karasaki, Hiroki Kokubo , Batmunkh Bumdelger , Nobuchika Kaji , Chiemi Sakai , Mari Ishida , and Masao Yoshizumi 1 Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundAngiotensin II type 1 receptor blockers (ARBs) have been shown to limit the growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial. This study aimed to investigate the molecular (...) (Journal of the American Heart Association)
12:10
Global, Regional, and National Burdens of Ischemic Heart Disease Attributable to Smoking From 1990 to 2019 - Liang Zhang, Zhuang Tong , Ruizheng Han , Ruiming Guo , Suhua Zang , Xin Zhang , Ruixia Yuan , and Yang Yang 1 Department of cardiovascular surgery The First Affiliated Hospital of Zhengzhou University China 2 Clinical Big Data Center The First Affiliated Hospital of Zhengzhou University China 3 Department of Ultrasound The Third Affiliated Hospital of Zhengzhou University China 4 Clinical Systems Biology Research Laboratories The First Affiliated Hospital of Zhengzhou University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundThis study was conducted to estimate the distribution of and changes in the global disease burden of ischemic heart disease attributable to smoking between 1990 and 2019.Methods and ResultsData used in (...) (Journal of the American Heart Association)
12:10
Health Status Outcomes in Older Adults Undergoing Chronic Total Occlusion Percutaneous Coronary Intervention - Dan D. Nguyen, Kensey L. Gosch , Rayan El?Zein , Paul S. Chan , William L. Lombardi , Dimitri Karmpaliotis , John A. Spertus , R. Michael Wyman , William J. Nicholson , Jeffrey W. Moses , J. Aaron Grantham , Adam C. Salisbury 1 Saint Luke’s Mid America Heart Institute Kansas City MO 2 University of Missouri?Kansas City Kansas City MO 3 University of Washington Medical Center Seattle WA 4 Morristown Medical Center Morristown NJ 5 Torrance Memorial Medical Center Torrance CA 6 Emory University Atlanta GA 7 Columbia University Medical Center New York NY 8 Saint Francis Heart Center Roslyn NY, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundAlthough chronic total occlusions (CTOs) are common in older adults, they are less likely to be offered CTO percutaneous coronary intervention for angina relief than younger adults. The health status (...) (Journal of the American Heart Association)
12:09
Derivation and Validation of an Algorithm to Detect Stroke Using Arm Accelerometry Data - Steven R. Messé, Scott E. Kasner , Brett L. Cucchiara , Michael L. McGarvey , Stephanie Cummings , Michael A. Acker , Nimesh Desai , Pavan Atluri , Grace J. Wang , Benjamin M. Jackson , and James Weimer 1 Department of Neurology University of Pennsylvania Philadelphia PA 2 Department of Surgery University of Pennsylvania Philadelphia PA 3 Department of Computer and Information Science University of Pennsylvania Philadelphia PA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundEarly diagnosis is essential for effective stroke therapy. Strokes in hospitalized patients are associated with worse outcomes compared with strokes in the community. We derived and validated an algorithm (...) (Journal of the American Heart Association)
12:09
Periodontal Disease Associated With Interstitial Myocardial Fibrosis: The Multiethnic Study of Atherosclerosis - Maria Doughan, Omar Chehab , Henrique Doria de Vasconcellos , Ralph Zeitoun , Vinithra Varadarajan , Bassel Doughan , Colin O. Wu , Michael J Blaha , David A. Bluemke , and Joao A. C. Lima 1 Division of Orthodontics, Department of Dentistry University of Maryland Baltimore MD 2 Division of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD 3 Faculty of Dental Surgery Côte d’Azur University Nice France 4 Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health Bethesda MD 5 Department of Radiology University of Wisconsin (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundPeriodontitis is a chronic inflammatory disease common among adults. It has been suggested that periodontal disease (PD) may be a contributing risk factor for cardiovascular disease; however, pathways (...) (Journal of the American Heart Association)
12:09
Growth Differentiation Factor?15 Predicts Mortality and Heart Failure Exacerbation But Not Ventricular Arrhythmias in Patients With Cardiomyopathy - M. Scott Binder, Lisa R. Yanek , Wanjun Yang , Barbara Butcher , Sanaz Norgard , Joseph E. Marine , Aravindan Kolandaivelu , Jonathan Chrispin , Neal S. Fedarko , Hugh Calkins , Brian O'Rourke , Katherine C. Wu , Gordon F. Tomaselli , and Andreas S. Barth 1 Department of Medicine Virginia Tech Carilion Roanoke VA 2 Department of Medicine Johns Hopkins University School of Medicine Baltimore MD 3 Albert Einstein College of Medicine and Montefiore Medicine Bronx (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundHeart failure (HF) has been increasing in prevalence, and a need exists for biomarkers with improved predictive and prognostic ability. GDF?15 (growth differentiation factor?15) is a novel biomarker (...) (Journal of the American Heart Association)

25 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:55
Cardioprotective Actions of a Glucagon?like Peptide?1 Receptor Agonist on Hearts Donated After Circulatory Death - Sachiko Kadowaki, M. Ahsan Siraj , Weiden Chen , Jian Wang , Marlee Parker , Anita Nagy , Chun?Po Steve Fan , Kyle Runeckles , Jing Li , Junko Kobayashi , Christoph Haller , Mansoor Husain , and Osami Honjo 1 Division of Cardiovascular Surgery The Hospital for Sick Children Toronto Ontario Canada 2 Department of Surgery University of Toronto Toronto Ontario Canada 3 Department of Medicine, Ted Rogers Centre for Heart Research, Peter Munk Cardiac Centre University of Toronto Toronto Ontario Canada 4 Department of Cardiac Surgery Guangzhou Women and Children’s Medical Center Guangzhou China (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundHeart transplantation with a donation after circulatory death (DCD) heart is complicated by substantial organ ischemia and ischemia–reperfusion injury. Exenatide, a glucagon?like peptide?1 receptor agonist, (...) (Journal of the American Heart Association)
11:55
Trends in Incidences and Survival Rates in Pediatric In?Hospital Cardiopulmonary Resuscitation: A Korean Population?Based Study - Jaeyoung Choi, Ah Young Choi , Esther Park , Suhyeon Moon , Meong Hi Son , and Joongbum Cho 1 Department of Critical Care Medicine Samsung Medical Center, Sungkyunkwan University School of Medicine Seoul Republic of Korea 2 Department of Pediatrics Chungnam National University Hospital Daejeon Republic of Korea 3 Department of Pediatrics Jeonbuk National University Children’s Hospital Jeonju Republic of Korea 4 Research Institute for Future Medicine Samsung Medical Center Seoul Republic of Korea 5 Department of Pediatrics Samsung Medical Center, Sungkyunkwan University School of Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundAlthough the outcome of cardiopulmonary resuscitation (CPR) is still unsatisfactory, there are few studies about temporal trends of in?hospital CPR incidence and mortality. We aimed to evaluate nationwide (...) (Journal of the American Heart Association)
11:55
Long?Term Visit?to?Visit Glycemic Variability as a Predictor of Major Adverse Limb and Cardiovascular Events in Patients With Diabetes - Jung?Chi Hsu, Yen?Yun Yang , Shu?Lin Chuang , Kuan?Chih Huang , Jen?Kuang Lee , and Lian?Yu Lin 1 Division of Cardiology, Department of Internal Medicine Fu Jen Catholic University Hospital New Taipei City Taiwan 2 Division of Cardiology, Department of Internal Medicine National Taiwan University College of Medicine and Hospital Taipei Taiwan 3 Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health National Taiwan University Taipei Taiwan 4 Department of Medical Research National Taiwan University Hospital Taipei Taiwan 5 Division of Cardiology, Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundPeripheral arterial disease (PAD) is a severe complication in patients with type 2 diabetes. Glycemic variability (GV) is associated with increased risks of developing microvascular and macrovascular (...) (Journal of the American Heart Association)
11:54
Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice - Emily D. Morales, Yongping Yue , Thais B. Watkins , Jin Han , Xiufang Pan , Aaron M. Gibson , Bryan Hu , Omar Brito?Estrada , Gang Yao , Catherine A. Makarewich , Gopal J. Babu , and Dongsheng Duan 1 Department of Molecular Microbiology and Immunology, School of Medicine The University of Missouri Columbia MO 2 Division of Molecular Cardiovascular Biology, Cincinnati Children’s Hospital Medical Center The Heart Institute Cincinnati OH 3 Department of Biomedical, Biological & Chemical Engineering, College of Engineering The University of Missouri Columbia MO 4 Department of Pediatrics The (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundCardiomyopathy is a leading health threat in Duchenne muscular dystrophy (DMD). Cytosolic calcium upregulation is implicated in DMD cardiomyopathy. Calcium is primarily removed from the cytosol by the (...) (Journal of the American Heart Association)
11:54
Influence of Social Determinants of Health on Heart Failure Outcomes: A Systematic Review - Kimberly R. Enard, Alyssa M. Coleman , R. Aver Yakubu , Briona C. Butcher , Donghua Tao , and Paul J. Hauptman 1 College for Public Health and Social Justice Saint Louis University Saint Louis MO 2 College of Medicine Baylor University Houston TX 3 Medical Center Library Saint Louis University Saint Louis MO 4 School of Medicine University of Nevada Reno NV J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundPrior research suggests an association between clinical outcomes in heart failure (HF) and social determinants of health (SDoH). Because providers should identify and address SDoH in care delivery, we (...) (Journal of the American Heart Association)
11:53
Is it Time to Retire the Diagnosis “Hypertensive Emergency”? - Flávio Danni Fuchs, Miguel Gus , Sandro Cadaval Gonçalves , and Sandra Costa Fuchs 1 Division of Cardiology Hospital de Clínicas de Porto Alegre Porto Alegre Rio Grande do Sul Brazil 2 Graduate Program in Cardiology, School of Medicine Universidade Federal do Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil 3 Division of Cardiology Hospital Moinhos de Vento Porto Alegre Rio Grande do Sul Brazil J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. (Journal of the American Heart Association)
11:52
Differential Associations of Cystatin C Versus Creatinine?Based Kidney Function With Risks of Cardiovascular Event and Mortality Among South Asian Individuals in the UK Biobank - Debbie C. Chen, Jennifer S. Lees , Kaiwei Lu , Rebecca Scherzer , Elaine Rutherford , Patrick B. Mark , Alka M. Kanaya , Michael G. Shlipak , and Michelle M. Estrella 1 Division of Nephrology, Department of Medicine University of California, San Francisco San Francisco CA 2 Kidney Health Research Collaborative San Francisco VA Medical Center & University of California, San Francisco San Francisco CA 3 Genentech, Inc. South San Francisco CA 4 Institute of Cardiovascular and Medical Sciences University of Glasgow United Kingdom 5 Glasgow Renal and Transplant Unit Queen Elizabeth University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundSouth Asian individuals have increased cardiovascular disease and mortality risks. Reliance on creatinine? rather than cystatin C–based estimated glomerular filtration rate (eGFRcys) may underestimate the (...) (Journal of the American Heart Association)
11:52
Correction to: Association of Low?Density Lipoprotein Cholesterol Levels During Statin Treatment With Cardiovascular and Renal Outcomes in Patients With Moderate Chronic Kidney Disease J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. (Journal of the American Heart Association)
11:52
Body Composition and Risk of Vascular?Metabolic Mortality Risk in 113 000 Mexican Men and Women Without Prior Chronic Disease - Louisa Gnatiuc Friedrichs, Rachel Wade , Jesus Alegre?Díaz , Raúl Ramirez?Reyes , Adrián Garcilazo?Ávila , Carlos Gonzáles?Carballo , Rogelio Santacruz?Benitez , Erwin Chiquete , William Herrington , Rory Collins , Richard Peto , Robert Clarke , Jaime Berumen , Jonathan R. Emberson , Pablo Kuri?Morales , and Roberto Tapia?Conyer 1 Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health University of Oxford United Kingdom 2 MRC Population Health Research Unit, Nuffield Department of Population Health University of Oxford United Kingdom 3 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundBody?mass index is the sum of fat mass index (FMI) and lean mass index (LMI), which vary by age, sex, and impact on disease outcomes. We investigated the separate and joint relevance of FMI and LMI with (...) (Journal of the American Heart Association)
11:51
Intracranial Hemorrhage Rate and Lesion Burden in Patients With Familial Cerebral Cavernous Malformation - Shantel Weinsheimer, Jeffrey Nelson , Adib A. Abla , Nerissa U. Ko , Cynthia Tsang , Obiora Okoye , Joseph M. Zabramski , Amy Akers , Atif Zafar , Marc C. Mabray , Blaine L. Hart , Leslie Morrison , Charles E. McCulloch , Helen Kim 1 Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research University of California San Francisco CA 2 Institute for Human Genetics, University of California San Francisco CA 3 Department of Neurological Surgery University of California San Francisco CA 4 Department of Neurology University of California San Francisco CA 5 Global (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundFamilial cerebral cavernous alformation (CCM) is an autosomal dominant disease caused by mutations inKRIT1,CCM2, orPDCD10. Cases typically present with multiple lesions, strong family history, and (...) (Journal of the American Heart Association)
11:51
Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function on Cardiovascular Death - David Hong, Seung Hun Lee , Doosup Shin , Ki Hong Choi , Hyun Kuk Kim , Sang Jin Ha , Hyun Sung Joh , Taek Kyu Park , Jeong Hoon Yang , Young Bin Song , Joo?Yong Hahn , Seung?Hyuk Choi , Hyeon?Cheol Gwon , and Joo Myung Lee 1 Division of Cardiology, Department of Internal Medicine Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine Seoul South Korea 2 Department of Internal Medicine and Cardiovascular Center Chonnam National University Hospital, Chonnam National University Medical School Gwangju South Korea 3 Division of Cardiology, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundCoronary microvascular dysfunction (CMD) has been considered as a possible cause of cardiac diastolic dysfunction. The current study evaluated the association between cardiac diastolic dysfunction and (...) (Journal of the American Heart Association)
11:51
Impact of Achieving Blood Pressure Targets and High Time in Therapeutic Range on Clinical Outcomes in Patients With Atrial Fibrillation Adherent to the Atrial Fibrillation Better Care Pathway: A Report From the COOL?AF Registry - Rungroj Krittayaphong, Arjbordin Winijkul , Komsing Methavigul , and Gregory Y. H. Lip 1 Division of Cardiology, Department of Medicine Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok Thailand 2 Department of Cardiology Central Chest Institute of Thailand Nonthaburi Thailand 3 Liverpool Centre for Cardiovascular Science University of Liverpool and Liverpool Heart & Chest Hospital Liverpool United Kingdom 4 Department of Clinical Medicine Aalborg University Aalborg (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundWe aimed to determine the effect of integrating Atrial Fibrillation Better Care pathway compliance in relation to achievement of systolic blood pressure (SBP) targets and good control of time in (...) (Journal of the American Heart Association)
11:50
Phenotyping of Elderly Patients With Heart Failure Focused on Noncardiac Conditions: A Latent Class Analysis From a Multicenter Registry of Patients Hospitalized With Heart Failure - Ryo Nakamaru, Yasuyuki Shiraishi , Nozomi Niimi , Takashi Kohno , Yuji Nagatomo , Makoto Takei , Takenori Ikoma , Kei Nishikawa , Munehisa Sakamoto , Shintaro Nakano , Shun Kohsaka , and Tsutomu Yoshikawa 1 Department of Cardiology Keio University School of Medicine Tokyo Japan 2 Department of Healthcare Quality Assessment The University of Tokyo Tokyo Japan 3 Department of Cardiovascular Medicine Kyorin University Faculty of Medicine Tokyo Japan 4 Department of Cardiology, National Defense Medical College Tokorozawa Japan 5 Department of Cardiology Saiseikai Central Hospital Tokyo Japan (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundThe burden of noncardiovascular conditions is becoming increasingly prevalent in patients with heart failure (HF). We aimed to identify novel phenogroups incorporating noncardiovascular conditions to (...) (Journal of the American Heart Association)
11:50
High Plasma Levels of Soluble Lectin?like Oxidized Low?Density Lipoprotein Receptor?1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity - Sara E. Stinson, Anna E. Jonsson , Mette K. Andersen , Morten A. V. Lund , Louise Aas Holm , Cilius E. Fonvig , Yun Huang , Evelina Stankevi? , Helene Bæk Juel , Lars Ängquist , Thorkild I. A. Sørensen , Emily L. Ongstad , Ranjitha Gaddipati , Joseph Grimsby , Christopher J. Rhodes , Oluf Pedersen , Michael Christiansen , Jens?Christian Holm , and Torben Hansen 1 Novo Nordisk Foundation Center for Basic Metabolic Research Faculty of Health and Medical Sciences, University of Copenhagen Denmark 2 The Children’s Obesity Clinic, Accredited European Centre for Obesity Management, Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundLectin?like oxidized low?density lipoprotein (ox?LDL) receptor?1 is a scavenger receptor for oxidized low?density lipoprotein. In adults, higher soluble lectin?like ox?LDL receptor?1 (sLOX?1) levels are (...) (Journal of the American Heart Association)
11:50
Cardiologic Manifestations in Omicron?Type Versus Wild?Type COVID?19: A Systematic Echocardiographic Study - Eihab Ghantous, Aviel Shetrit , Aviram Hochstadt , Ariel Banai , Lior Lupu , Erez Levi , Yishay Szekely , Nadav Schellekes , Tammy Jacoby , David Zahler , Tamar Itach , Philippe Taieb , Sheizaf Gefen , Dana Viskin , Lia Shidlansik , Amos Adler , Ekaterina Levitsky , Ofer Havakuk , Merav Ingbir , Shmuel Banai , and Yan Topilsky 1 Department of Cardiology, Tel Aviv Sourasky Medical Center and Sackler School of Medicine Tel Aviv University Tel Aviv Israel 2 Tel Aviv Sourasky Medical Center and Sackler School of Medicine Tel Aviv University Tel Aviv Israel 3 Clinical Microbiology Laboratory, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundInformation about the cardiac manifestations of the Omicron variant of COVID?19 is limited. We performed a systematic prospective echocardiographic evaluation of consecutive patients hospitalized with the (...) (Journal of the American Heart Association)
11:49
Improvement in Blood Pressure Control in Safety Net Clinics Receiving 2 Versions of a Scalable Quality Improvement Intervention: BP MAP A Pragmatic Cluster Randomized Trial - Valy Fontil, Madelaine Faulkner Modrow , Rhonda M. Cooper?DeHoff , Gregory Wozniak , Michael Rakotz , Jonathan Todd , Kristen Azar , Linda Murakami , Margaret Sanders , Alanna M. Chamberlain , Emily O'Brien , April Lee , Thomas Carton , and Mark J. Pletcher 1 University of California San Francisco San Francisco CA 2 University of Florida Gainesville FL 3 The American Medical Association Chicago IL 4 OCHIN Portland OR 5 Louisiana Public Health Institute New Orleans LA 6 Mayo Clinic Rochester MN 7 Duke University Durham (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundUncontrolled blood pressure (BP) remains a leading cause of death in the United States. The American Medical Association developed a quality improvement program to improve BP control, but it is unclear (...) (Journal of the American Heart Association)
11:49
Association Between Duration of Transient Neurological Events and Diffusion?Weighted Brain Lesions - Raed A. Joundi, Amy Y. X. Yu , Eric E. Smith , Charlotte Zerna , Andrew M. Penn , Robert F. Balshaw , Kristine Votova , Maximilian B. Bibok , Melanie Penn , Viera Saly , Janka Hegedus , Shelagh B. Coutts 1 Division of Neurology, Hamilton Health Sciences McMaster University & Population Health Research Institute Hamilton Ontario Canada 2 Division of Neurology, Department of Medicine University of Toronto, Sunnybrook Health Sciences Centre Toronto Ontario Canada 3 Departments of Clinical Neurosciences and Community Health Sciences University of Calgary Alberta Canada 4 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundThe relationship between duration of transient neurological events and presence of diffusion?weighted lesions by symptom type is unclear.Methods and ResultsThis was a substudy of SpecTRA (Spectrometry for (...) (Journal of the American Heart Association)

23 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:45
Real?World Disparities in Remote Follow?Up of Cardiac Implantable Electronic Devices and Impact of the COVID?19 Pandemic: A Single?Center Experience - H. Immo Lehmann, Krishan Sharma , Roma Bhatia , Theresa Mills , Joshua Lang , Guoping Li , Carl Andrews , Jay Cullivan , Jagmeet Singh , and Theofanie Mela 1 Department of Cardiology Massachusetts General Hospital Boston MA 2 Harvard Medical School Cambridge MA 3 Department of Medicine Massachusetts General Hospital Boston MA 4 Brigham and Women’s Hospital Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundRemote monitoring (RM) of cardiac implantable electronic devices has been shown to improve cardiovascular morbidity and mortality. To date, no studies have investigated disparities in use and delivery of (...) (Journal of the American Heart Association)
11:45
Prognostic Implication of Mitral Valve Disease and Its Progression in East Asian Patients With Hypertrophic Cardiomyopathy - Dae?Young Kim, Jiwon Seo , Iksung Cho , Geu?Ru Hong , Jong?Won Ha , and Chi Young Shim 1 Division of Cardiology, Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Korea J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundHypertrophic cardiomyopathy (HCM) is a genetic disorder affecting not only the myocardium but also the mitral valve (MV) and its apparatus. This study aimed to investigate the prognostic implication of MV (...) (Journal of the American Heart Association)
11:44
Lectin?Like Oxidized Low?Density Lipoprotein Receptor 1 Inhibition in Type 2 Diabetes: Phase 1 Results - Andrea L. Vavere, Marvin Sinsakul , Emily L. Ongstad , Ye Yang , Vijayalakshmi Varma , Christopher Jones , Joanne Goodman , Vincent F. S. Dubois , Angelica L. Quartino , Sotirios K. Karathanasis , Liron Abuhatzira , Anna Collén , Charalambos Antoniades , Michael J. Koren , Ruchi Gupta , and Richard T. George 1 Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, AstraZeneca Gaithersburg MD USA 2 Bioscience Cardiovascular, Research and Early Development, Cardiovascular, Renal and Metabolism BioPharmaceuticals R&D, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundBlockade of the lectin?like oxidized low?density lipoprotein receptor?1 (LOX?1) is a potentially attractive mechanism for lowering inflammatory and lipid risk in patients with atherosclerosis. This study aims (...) (Journal of the American Heart Association)
11:44
Effects of Ablation Versus Drug Therapy on Quality of Life by Sex in Atrial Fibrillation: Results From the CABANA Trial - Emily P. Zeitler, Yanhong Li , Adam P. Silverstein , Andrea M. Russo , Jeanne E. Poole , Melanie R. Daniels , Hussein R. Al?Khalidi , Kerry L. Lee , Tristram D. Bahnson , Kevin J. Anstrom , Douglas L. Packer , Daniel B. Mark , and 1 Dartmouth Health and The Dartmouth Institute Lebanon NH USA 2 Duke Clinical Research Institute, Duke University Durham NC USA 3 Division of Cardiovascular Disease Cooper Medical School of Rowan University Camden NJ USA 4 University of Washington Medical Center Seattle WA USA 5 Department of Biostatistics and Bioinformatics Duke University Durham NC USA 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundWomen with atrial fibrillation (AF) demonstrate more AF?related symptoms and worse quality of life (QOL). Whether increased use of ablation in women reduces sex?related QOL differences is unknown. (...) (Journal of the American Heart Association)
11:44
Stroke Recurrence Following 28 Days After First Stroke in Men and Women 2012 to 2020: Observations From the Swedish Stroke Register - Marie Eriksson, Anton Grundberg , Erik Inge , and Mia von Euler 1 Department of Statistics, USBE Umeå University Umeå Sweden 2 Department of Neurology and Rehabilitation, Faculty of Medicine and Health Örebro University Örebro Sweden J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundStroke incidence, care, and survival show continuous improvements in Sweden, including no or decreasing disparities between men and women. In this study, we aimed to estimate and compare the risk of (...) (Journal of the American Heart Association)
11:43
Magnetic Resonance Imaging?Derived Microvascular Perfusion Modeling to Assess Peripheral Artery Disease - Olga A. Gimnich, Tatiana Belousova , Christina M. Short , Addison A. Taylor , Vijay Nambi , Joel D. Morrisett , Christie M. Ballantyne , Jean Bismuth , Dipan J. Shah , and Gerd Brunner 1 Penn State Heart and Vascular Institute, Pennsylvania State University College of Medicine Hershey PA 2 Section of Cardiovascular Research, Department of Medicine Baylor College of Medicine Houston TX 3 Department of Medicine, Section of Cardiology Baylor College of Medicine Houston TX 4 Michael E DeBakey VA Medical Center Houston TX 5 Methodist DeBakey Heart and Vascular Center Houston Methodist Hospital (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundComputational fluid dynamics has shown good agreement with contrast?enhanced magnetic resonance imaging measurements in cardiovascular disease applications. We have developed a biomechanical model of (...) (Journal of the American Heart Association)
11:43
Association of Depression and Poor Mental Health With Cardiovascular Disease and Suboptimal Cardiovascular Health Among Young Adults in the United States - Yaa A. Kwapong, Ellen Boakye , Sadiya S. Khan , Michael C. Honigberg , Seth S. Martin , Chigolum P. Oyeka , Allison G. Hays , Pradeep Natarajan , Mamas A. Mamas , Roger S. Blumenthal , Michael J. Blaha , and Garima Sharma 1 Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Diseases Johns Hopkins School of Medicine Baltimore MD 2 Department of Medicine Northwestern University Chicago IL 3 Department of Medicine Massachusetts General Hospital Boston MA 4 Cardiovascular Research Center and Center for Genomic Medicine Massachusetts General Hospital Boston MA 5 Cardiovascular (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundDepression is a nontraditional risk factor for cardiovascular disease (CVD). Data on the association of depression and poor mental health with CVD and suboptimal cardiovascular health (CVH) among young (...) (Journal of the American Heart Association)

18 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:34
Association of Eating and Sleeping Intervals With Weight Change Over Time: The Daily24 Cohort - Di Zhao, Eliseo Guallar , Thomas B. Woolf , Lindsay Martin , Harold Lehmann , Janelle Coughlin , Katherine Holzhauer , Attia A. Goheer , Kathleen M. McTigue , Michelle R. Lent , Marquis Hawkins , Jeanne M. Clark , and Wendy L. Bennett 1 Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD 2 Department of Physiology Johns Hopkins University School of Medicine Baltimore MD 3 Division of General Internal Medicine Johns Hopkins University School of Medicine Baltimore MD 4 Division of Health Sciences Informatics Johns Hopkins University School of Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundWe aim to evaluate the association between meal intervals and weight trajectory among adults from a clinical cohort.Methods and ResultsThis is a multisite prospective cohort study of adults recruited from (...) (Journal of the American Heart Association)

17 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:54
Developmental Care for Hospitalized Infants With Complex Congenital Heart Disease: A Science Advisory From the American Heart Association - Amy Jo Lisanti, Karen C. Uzark , Tondi M. Harrison , Jennifer K. Peterson , Samantha C. Butler , Thomas A. Miller , Kiona Y. Allen , Steven P. Miller , Courtney E. Jones , and J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. Developmental disorders, disabilities, and delays are a common outcome for individuals with complex congenital heart disease, yet targeting early factors influencing these conditions after birth and during the (...) (Journal of the American Heart Association)
13:30
Congenital Heart Disease and Fertility: A Danish Nationwide Cohort Study Including Both Men and Women - Louise F. Udholm, Linn H. Arendt , Ulla B. Knudsen , Cecilia H. Ramlau?Hansen , and Vibeke E. Hjortdal 1 Department of Cardiothoracic Surgery Copenhagen University Hospital Copenhagen Denmark 2 Department of Clinical Medicine Copenhagen University Copenhagen Denmark 3 Department of Public Health, Research Unit for Epidemiology Aarhus University Aarhus Denmark 4 Department of Obstetrics and Gynaecology Horsens Regional Hospital Horsens Denmark 5 Department of Clinical Medicine Aarhus University Aarhus (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundDespite an increasing number of patients with congenital heart disease (CHD) reaching reproductive age, the fertility of these patients remains undescribed. Therefore, the aim of the study was to evaluate (...) (Journal of the American Heart Association)

16 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:19
Heart?Brain Team Approach of Acute Myocardial Infarction Complicating Acute Stroke: Characteristics of Guideline?Recommended Coronary Revascularization and Antithrombotic Therapy and Cardiovascular and Bleeding Outcomes - Toshiaki Suzuki, Yu Kataoka , Masayuki Shiozawa , Kensuke Morris , Eri Kiyoshige , Kunihiro Nishimura , Kota Murai , Kenichiro Sawada , Takamasa Iwai , Hideo Matama , Satoshi Honda , Masashi Fujino , Shuichi Yoneda , Kensuke Takagi , Fumiyuki Otsuka , Yasuhide Asaumi , Masatoshi Koga , Masafumi Ihara , Kazunori Toyoda , Kenichi Tsujita , and Teruo Noguchi 1 Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center Suita, Osaka Japan 2 Department of Advanced Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University Kumamoto Japan 3 Department (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundAcute myocardial infarction (AMI) infrequently occurs after acute stroke. The Heart?brain team approach has a potential to appropriately manage this poststroke cardiovascular complication. However, (...) (Journal of the American Heart Association)
12:18
Reverse Atrial Remodeling in Heart Failure With Recovered Ejection Fraction - Yuxi Sun, Xuefu Chen , Yanli Zhang , Yao Yu , Xinxin Zhang , Jinping Si , Zijie Ding , Yunlong Xia , Gary Tse , and Ying Liu 1 Department of Cardiology, West China Hospital Sichuan University Chengdu China 2 Department of Cardiology The First Affiliated Hospital of Dalian Medical University Dalian China 3 Kent and Medway Medical School University of Kent and Canterbury Christ Church University Canterbury United Kingdom 4 School of Nursing and Health Studies, Hong Kong Metropolitan University Hong Kong (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundHeart failure with recovered ejection fraction (HFrecEF) has been a newly recognized entity since 2020. However, the concept has primarily focused on left ventricular ejection fraction improvement, with (...) (Journal of the American Heart Association)
12:18
Large?Scale Metabolomics and the Incidence of Cardiovascular Disease - Lars Lind, Tove Fall , Johan Ärnlöv , Sölve Elmståhl , and Johan Sundström 1 Department of Medical Sciences Uppsala University Uppsala Sweden 2 Division of Family Medicine and Primary Care, Department of Neurobiology, Care Science and Society Karolinska Institutet Huddinge Sweden 3 School of Health and Social Studies Dalarna University Falun Sweden 4 Division of Geriatric Medicine, Department of Clinical Sciences in Malmö Lund University Malmö Sweden J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundThe study aimed to show the relationship between a large number of circulating metabolites and subsequent cardiovascular disease (CVD) and subclinical markers of CVD in the general population.Methods and (...) (Journal of the American Heart Association)
12:18
Inflection Points in Blood Pressure Trajectories Preceding Hypertension Onset in Different Age Groups - Chengzhang Liu, Cheng Zu , Qiguo Meng , Rui Li , Yuanyuan Zhang , Panpan He , Chun Zhou , Mengyi Liu , Ziliang Ye , and Xianhui Qin 1 Division of Nephrology Nanfang Hospital, Southern Medical University, National Clinical Research Center for Kidney Disease, State Key Laboratory of Organ Failure Research, Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory Guangzhou China 2 Department of Epidemiology and Biostatistics, School of Public Health Anhui Medical University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundUnderstanding the natural history of elevated blood pressure (BP) is important to determine the window for primary prevention of hypertension. The authors aimed to investigate the natural history of (...) (Journal of the American Heart Association)
12:18
Impaired Elastic Properties of the Ascending Aorta in Fetuses With Coarctation of the Aorta - Ran Xu, Dan Zhou , Yushan Liu , Longmei Yao , Li Xie , Minghui Liu , Qichang Zhou , and Shi Zeng 1 Department of Ultrasound Diagnosis The Second Xiangya Hospital, Central South University Changsha Hunan China 2 Department of Urology The Second Xiangya Hospital, Central South University Changsha Hunan China 3 Department of Cardiology and Cardiovascular surgery The Second Xiangya Hospital, Central South University Changsha Hunan China J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundAbnormal aortic elastic properties are major notable vasculopathy involved in coarctation of the aorta (CoA). However, there are no reports on aortic wall elastic characteristics in fetuses with (...) (Journal of the American Heart Association)
12:17
Circulating Progenitor Cells Are Associated With Bioprosthetic Aortic Valve Deterioration: A Preliminary Study - Yoshihisa Kanaji, Ilke Ozcan , Takumi Toya , Rajiv Gulati , Melissa Young , Tsunekazu Kakuta , Lilach O. Lerman , and Amir Lerman 1 Department of Cardiovascular Medicine Rochester MN 2 Division of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Ibaraki Japan 3 Division of Cardiology National Defense Medical College Tokorozawa Japan 4 Division of Nephrology and Hypertension, Mayo Clinic Mayo Clinic Rochester MN J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundMechanisms underlying bioprosthetic valve deterioration are multifactorial and incompletely elucidated. Reparative circulating progenitor cells, and conversely calcification?associated osteocalcin (...) (Journal of the American Heart Association)
12:17
Dual?Antiplatelet Therapy After Percutaneous Coronary Intervention: How Short Is Too Short? - Philipp Mourikis, and Amin Polzin 1 Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty Heinrich Heine University Medical Center Dusseldorf Dusseldorf Germany J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. (Journal of the American Heart Association)
12:17
Long?Term Outcomes and Duration of Dual Antiplatelet Therapy After Coronary Intervention With Second?Generation Drug?Eluting Stents: The Veterans Affairs Extended DAPT Study - Scott Kinlay, Melissa M. Young , Rebecca Sherrod , and David R. Gagnon 1 Veterans Affairs Boston Healthcare System West Roxbury MA 2 Harvard Medical School Boston MA 3 Department of Biostatistics, Massachusetts Veterans Epidemiology Research & Information Center (MAVERIC) VA Boston Healthcare System Boston MA 4 Brigham and Women’s Hospital Boston MA 5 Boston University Medical School Boston MA 6 Boston University School of Public Health Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundRecent guidelines on dual antiplatelet therapy (DAPT) duration after percutaneous coronary intervention (PCI) balance the subsequent risks of major bleeding with ischemic events. Although generally (...) (Journal of the American Heart Association)
12:17
Scavenger Receptors in Myocardial Infarction and Ischemia/Reperfusion Injury: The Potential for Disease Evaluation and Therapy - Jishou Zhang, Wen Ding , Jianfang Liu , Jun Wan , and Menglong Wang 1 Department of Cardiology Renmin Hospital of Wuhan University Wuhan China 2 Cardiovascular Research Institute Wuhan University Wuhan China 3 Hubei Key Laboratory of Cardiology Wuhan China 4 Department of Radiology The First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou China J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. Scavenger receptors (SRs) are a structurally heterogeneous superfamily of evolutionarily conserved receptors that are divided into classes A to J. SRs can recognize multiple ligands, such as modified lipoproteins, (...) (Journal of the American Heart Association)

12 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:20
Elevated Uric Acid Is Associated With New?Onset Atrial Fibrillation: Results From the Swedish AMORIS Cohort - Mozhu Ding, Ngoc Nguyen Viet , Bruna Gigante , Viktor Lind , Niklas Hammar , and Karin Modig 1 Unit of Epidemiology Institute of Environmental Medicine, Karolinska Institutet Stockholm Sweden 2 Division of Cardiovascular Medicine, Department of Medicine Karolinska Institutet and Division of Cardiology, Danderyd University Hospital Stockholm Sweden 3 Division of Cardiovascular Medicine, Department of Clinical Sciences Danderyd Hospital, Karolinska Institutet Stockholm Sweden 4 Department of Cardiology Danderyd University Hospital Stockholm (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundThe role of uric acid is gaining increasing importance in the evaluation of cardiovascular disease, but its relationship with atrial fibrillation (AF) is unclear. This study aims to investigate the (...) (Journal of the American Heart Association)

11 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:03
In?Hospital ECG Findings, Changes in Medical Management, and Cardiovascular Outcomes in Patients With Acute Stroke or Transient Ischemic Attack - Manuel C. Olma, Serdar Tütüncü , Cornelia Fiessler , Claudia Kunze , Michael Krämer , Lena Steindorf?Sabath , Muhammad Jawad?Ul?Qamar , Paulus Kirchhof , Ulrich Laufs , Johannes Schurig , Peter Kraft , Joachim Röther , Albrecht Günther , Götz Thomalla , Boris Dimitrijeski , Darius G. Nabavi , Roland Veltkamp , Peter U. Heuschmann , Karl Georg Haeusler , Matthias Endres 1 Center for Stroke Research Berlin Charité ? Universitätsmedizin Berlin Berlin Germany 2 Institute of Clinical Epidemiology and Biometry University Würzburg Würzburg Germany 3 Institute of Cardiovascular Sciences College of Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundIn patients with acute ischemic stroke, little is known regarding the frequency of abnormal ECG findings other than atrial fibrillation and their association with cardiovascular outcomes. We aim to (...) (Journal of the American Heart Association)
11:03
Gaps in the Care of Pulmonary Hypertension: A Cross?Sectional Patient Simulation Study Among Practicing Cardiologists and Pulmonologists - Enrico de Belen, John W. McConnell , Jean M. Elwing , David Paculdo , Ian Cabaluna , Jörg Linder , and John W. Peabody 1 QURE Healthcare San Francisco CA 2 Norton Healthcare Louisville KY 3 UC Health Cincinnati OH 4 Janssen?Cilag GmbH Neuss Germany 5 University of California San Francisco CA 6 University of California Los Angeles CA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundDiagnosis of pulmonary hypertension (PH) is often delayed or missed, leading to disease progression and missed treatment opportunities. In this study, we measured variation in care provided by (...) (Journal of the American Heart Association)
11:02
Effects of the Dietary Approaches to Stop Hypertension Diet on Change in Cardiac Biomarkers Over Time: Results From the DASH?Sodium Trial - Matthew J. Belanger, Lara C. Kovell , Ruth?Alma Turkson?Ocran , Kenneth J. Mukamal , Xiaoran Liu , Lawrence J. Appel , Edgar R. Miller , Frank M. Sacks , Robert H. Christenson , Heather Rebuck , Alex R. Chang , and Stephen P. Juraschek 1 Division of Cardiology, Department of Medicine Johns Hopkins Medical Institutions Baltimore MD 2 Division of Cardiology University of Massachusetts Chan Medical School Worcester MA 3 Beth Israel Deaconess Medical Center Harvard Medical School Boston MA 4 Harvard T.H. Chan School of Public Health, Harvard Medical School Brigham and Women’s Hospital Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundThe Dietary Approaches to Stop Hypertension (DASH) diet has been shown to reduce biomarkers of cardiovascular disease. We aimed to characterize the time course of change in biomarkers of cardiac injury (...) (Journal of the American Heart Association)
11:02
Evidence of Carotid Atherosclerosis Vulnerability Regression in Real Life From Magnetic Resonance Imaging: Results of the MAGNETIC Prospective Study - Oronzo Catalano, Giulia Bendotti , Teresa L. Aloi , Alberto Ferrari Bardile , Mirella Memmi , Patrick Gambelli , Daniela Zanaboni , Alessandra Gualco , Emanuela Cattaneo , Antonio Mazza , Mauro Frascaroli , Esmeralda Eshja , Riccardo Bellazzi , Paolo Poggi , Giovanni Forni , and Maria Teresa La Rovere 1 Division of Cardiology Istituti Clinici Scientifici Maugeri IRCCS Pavia Italy 2 Angiology Unit Istituti Clinici Scientifici Maugeri IRCCS Pavia Italy 3 Molecular Cardiology Istituti Clinici Scientifici Maugeri IRCCS Pavia Italy 4 Department of Electrical, Computer and Biomedical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundAtherosclerosis vulnerability regression has been evidenced mostly in randomized clinical trials with intensive lipid?lowering therapy. We aimed to demonstrate vulnerability regression in real life, with a (...) (Journal of the American Heart Association)
11:02
Age?Dependent Association Between Modifiable Risk Factors and Incident Cardiovascular Disease - Hidehiro Kaneko, Yuichiro Yano , Akira Okada , Hidetaka Itoh , Yuta Suzuki , Isao Yokota , Kojiro Morita , Katsuhito Fujiu , Nobuaki Michihata , Taisuke Jo , Satoko Yamaguchi , Norifumi Takeda , Hiroyuki Morita , Koichi Node , Toshimasa Yamauchi , Masaomi Nangaku , Takashi Kadowaki , John W. McEvoy , Carolyn S. P. Lam , Hideo Yasunaga , and Issei Komuro 1 Department of Cardiovascular Medicine The University of Tokyo Japan 2 Department of Advanced Cardiology The University of Tokyo Japan 3 YCU Center for Novel and Exploratory Clinical Trials Yokohama City University Hospital Yokohama Japan (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundThere have been limited data examining the age?dependent relationship of wide?range risk factors with the incidence of each subtype of cardiovascular disease (CVD) event. We assessed age?related associations (...) (Journal of the American Heart Association)
11:02
Aortic Valve Reconstruction With Autologous Pericardium Versus a Bioprosthesis: The Ozaki Procedure in Perspective - Shinya Unai, Shigeyuki Ozaki , Douglas R. Johnston , Tomohiro Saito , Jeevanantham Rajeswaran , Lars G. Svensson , Eugene H. Blackstone , and Gösta B. Pettersson 1 Department of Thoracic and Cardiovascular Surgery Heart, Vascular, and Thoracic Institute Cleveland Clinic Cleveland OH 2 Department of Cardiovascular Surgery Toho University Ohashi Medical Center Tokyo Japan 3 Department of Quantitative Health Sciences Lerner Research Institute Cleveland Clinic Cleveland (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundWe assessed the Ozaki procedure, aortic valve reconstruction using autologous pericardium, with respect to its learning curve, hemodynamic performance, and durability compared with a stented (...) (Journal of the American Heart Association)
11:01
Adolescent Psychological Assets and Cardiometabolic Health Maintenance in Adulthood: Implications for Health Equity - Farah Qureshi, Anne?Josee Guimond , Elaine Tsao , Scott Delaney , Julia K. Boehm , and Laura D. Kubzansky 1 Department of Population, Family and Reproductive Health Johns Hopkins Bloomberg School of Public Health Baltimore MD 2 Department of Social and Behavioral Sciences Harvard T.H. Chan School of Public Health Boston MA 3 Lee Kum Sheung Center for Health and Happiness Harvard T.H. Chan School of Public Health Boston MA 4 Department of Psychology Chapman University Orange (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundPositive cardiometabolic health (CMH) is defined as meeting recommended levels of multiple cardiometabolic risk factors in the absence of manifest disease. Prior work finds that few (...) (Journal of the American Heart Association)
11:01
High Prevalence of Geriatric Conditions Among Older Adults With Cardiovascular Disease - Amal Aïdoud, Wassim Gana , Fanny Poitau , Camille Debacq , Victoire Leroy , Jacques?Alexis Nkodo , Pierre Poupin , Denis Angoulvant , and Bertrand Fougère 1 Division of Geriatric Medicine Tours University Hospital Tours France 2 EA4245 Transplantation, Immunologie, Inflammation Tours University Tours France 3 Cardiology Unit Trousseau Hospital, Tours University Hospital Tours France 4 EA 7505 Education, Ethics, Health Tours University Tours France 5 INSERM CIC 1415 Tours University Hospital Tours France 6 INSERM, SPHERE U1246 Tours University, Nantes University Tours (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. As the population ages, the global cardiovascular disease burden will continue to increase, particularly among older adults. Increases in life expectancy and better cardiovascular care have significantly reshaped (...) (Journal of the American Heart Association)

10 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:14
Prescribing Trends of Oral Anticoagulants in US Patients With Cirrhosis and Nonvalvular Atrial Fibrillation - Tracey G. Simon, Sebastian Schneeweiss , Daniel E. Singer , Sushama Kattinakere Sreedhara , and Kueiyu Joshua Lin 1 Division of Pharmacoepidemiology and Pharmacoeconomics Department of Medicine, Brigham and Women’s Hospital Harvard Medical School Boston MA 2 Division of Gastroenterology and Hepatology Department of Medicine, Massachusetts General Hospital Harvard Medical School Boston MA 3 Division of General Internal Medicine Department of Medicine Massachusetts General Hospital, Harvard Medical School Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundMany patients with cirrhosis have concurrent nonvalvular atrial fibrillation (NVAF). Data are lacking regarding recent oral anticoagulant (OAC) usage trends among US patients with cirrhosis and (...) (Journal of the American Heart Association)
11:13
US Trends in Cholesterol Screening, Lipid Levels, and Lipid?Lowering Medication Use in US Adults, 1999 to 2018 - Yumin Gao, Lochan M. Shah , Jie Ding , and Seth S. Martin 1 Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD 2 Johns Hopkins Bloomberg School of Public Health Baltimore MD J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 3, February 7, 2023. BackgroundUnderstanding current trends in cholesterol screening, lipid levels, and lipid management therapies may inform health policy and practice.Methods and ResultsIn 50 928 US adult National Health and (...) (Journal of the American Heart Association)
11:14
Cause?Specific Mortality of Patients With Atrial Septal Defect and Up to 50 Years of Follow?Up - Valtteri Muroke, Mikko Jalanko , Jari Haukka , and Juha Sinisalo 1 Department of Cardiology Helsinki University Hospital and University of Helsinki Helsinki Finland 2 Department of Public Health, Clinicum University of Helsinki Helsinki Finland J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundThis study aimed to evaluate the long?term mortality and cause?specific mortality of patients with atrial septal defect (ASD) in a nationwide cohort.Methods and ResultsAll patients diagnosed with simple ASD (...) (Journal of the American Heart Association)
11:13
Independent Relevance of Different Measures of Adiposity for Carotid Intima?Media Thickness in 40 000 Adults in UK Biobank - Preyanka Pillay, Jennifer Carter , Hannah Taylor , Sarah Lewington , and Robert Clarke 1 Nuffield Department of Population Health University of Oxford UK J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundUncertainty persists about carotid intima–media thickness (CIMT) as a marker of subclinical atherosclerosis and the independent relevance of different measures of adiposity for CIMT. We assessed the (...) (Journal of the American Heart Association)
11:12
Social Determinants of Cardiovascular Health: A Longitudinal Analysis of Cardiovascular Disease Mortality in US Counties From 2009 to 2018 - Heejung Son, Donglan Zhang , Ye Shen , Anna Jaysing , Jielu Zhang , Zhuo Chen , Lan Mu , Junxiu Liu , Janani Rajbhandari?Thapa , Yan Li , and José A. Pagán 1 Department of Epidemiology & Biostatistics, College of Public Health University of Georgia Athens GA 2 Division of Health Services Research, Department of Foundations of Medicine New York University Long Island School of Medicine Mineola NY 3 Department of Geography University of Georgia Athens GA 4 Department of Health Policy and Management, College of Public Health University of Georgia Athens GA 5 Department of Population Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundDisparities in cardiovascular disease (CVD) outcomes persist across the United States. Social determinants of health play an important role in driving these disparities. The current study aims to identify (...) (Journal of the American Heart Association)

3 January

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

04:09
Journal of the American Heart Association: The Next Stage of the Journey - Bruce Ovbiagele 1 Department of Neurology University of California San Francisco CA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)

30 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:39
Canagliflozin Improves Myocardial Perfusion, Fibrosis, and Function in a Swine Model of Chronic Myocardial Ischemia - Sharif A. Sabe, Cynthia M. Xu , Mohamed Sabra , Dwight Douglas Harris , Akshay Malhotra , Ahmed Aboulgheit , Madigan Stanley , M. Ruhul Abid , and Frank W. Sellke 1 Division of Cardiothoracic Surgery, Department of Surgery, Cardiovascular Research Center, Rhode Island Hospital Alpert Medical School of Brown University, Rhode Island Hospital Providence RI J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundSodium?glucose cotransporter?2 inhibitors are cardioprotective independent of glucose control, as demonstrated in animal models of acute myocardial ischemia and clinical trials. The functional and molecular (...) (Journal of the American Heart Association)
11:37
Validation of a Brief Dietary Questionnaire for Use in Clinical Practice: Mini?EAT (Eating Assessment Tool) - Kyla M. Lara?Breitinger, Jose R. Medina Inojosa , Zhuo Li , Sarka Kunzova , Amir Lerman , Stephen L. Kopecky , and Francisco Lopez?Jimenez 1 Mayo Clinic, Department of Cardiovascular Medicine Rochester MN 2 Mayo Clinic, Division of Biomedical Statistics and Informatics Jacksonville FL 3 International Clinical Research Center St Anne’s University Hospital Brno Brno Czech Republic J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThere is a scarcity of validated rapid dietary screening tools for patient use in the clinical setting to improve health and reduce cardiovascular risk. The Healthy Eating Index (HEI) 2015 measures (...) (Journal of the American Heart Association)
11:37
Treatment and Implications of Vascular Endothelial Growth Factor Inhibitor?Induced Blood Pressure Rise: A Clinical Cohort Study - Daan C. H. van Dorst, Sumeyye Kabadayi , Esther Oomen?de Hoop , A.H. Jan Danser , Ron H. J. Mathijssen , and Jorie Versmissen 1 Department of Medical Oncology, Erasmus MC Cancer Institute Erasmus MC University Medical Center Rotterdam The Netherlands 2 Division of Vascular Medicine and Pharmacology, Department of Internal Medicine Erasmus MC University Medical Center Rotterdam The Netherlands 3 Department of Hospital Pharmacy Erasmus MC University Medical Center Rotterdam The (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundAnti?cancer vascular endothelial growth factor inhibitors (VEGFI) frequently induce a rise in blood pressure (BP). The most effective treatment of this BP rise is currently unknown, and risk factors and its (...) (Journal of the American Heart Association)
11:37
Bedside Prognostication in Decompensated Heart Failure: No “Easy Button” - Madhumathi Rao 1 University of Kentucky, Albert B. Chandler Medical Center Lexington KY J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:37
New Classification for the Combined Assessment of the Fractional Excretion of Urea Nitrogen and Estimated Plasma Volume Status in Acute Heart Failure - Kazutaka Nogi, Tomoya Ueda , Takuya Nakamura , Maki Nogi , Satomi Ishihara , Yasuki Nakada , Yukihiro Hashimoto , Hitoshi Nakagawa , Taku Nishida , Ayako Seno , Kenji Onoue , Makoto Watanabe , and Yoshihiko Saito 1 Department of Cardiovascular Medicine Nara Medical University Kashihara Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe fractional excretion of urea nitrogen (FEUN) has been used as a renal blood flow index related to cardiac output, and the estimated plasma volume status (ePVS) as a body fluid volume index. However, (...) (Journal of the American Heart Association)
11:37
Integrating Diet Screening Into Routine Clinical Care: The Time Is Now - Maya K. Vadiveloo, Anne N. Thorndike , and Alice H. Lichtenstein 1 Department of Nutrition and Food Sciences, College of Health Sciences University of Rhode Island Kingston RI 2 Harvard Medical School Boston MA 3 Division of General Internal Medicine, Department of Medicine Massachusetts General Hospital Boston MA 4 Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging Tufts University Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:36
Vascular Closure Devices after Femoral Arteriotomy: Insight in High?Risk Patients - Ravi Thakker, Jose C. Iturrizaga , and Tareq Abu Sharifeh 1 Division of Cardiovascular Disease University of Texas Medical Branch Galveston TX J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:39
Preoperative Factors Predict Memory Decline After Coronary Artery Bypass Grafting or Percutaneous Coronary Intervention in an Epidemiological Cohort of Older Adults - Angelina B. Tang, L. Grisell Diaz?Ramirez , Alexander K. Smith , Sei J. Lee , and Elizabeth L. Whitlock 1 UCSF School of Medicine San Francisco CA 2 Division of Geriatrics, Department of Medicine UCSF School of Medicine San Francisco CA 3 Department of Anesthesia & Perioperative Care UCSF School of Medicine San Francisco CA United States J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundDurable memory decline may occur in older adults after surgical (coronary artery bypass grafting [CABG]) or nonsurgical (percutaneous coronary intervention) coronary revascularization. However, it is (...) (Journal of the American Heart Association)
11:39
Left Ventricular Apical Aneurysm in Fabry Disease: Implications for Clinical Significance and Risk Stratification - Hao?Chih Chang, Ling Kuo , Shih?Hsien Sung , Ching?Yao Weng , Chun?Ku Chen , Dau?Ming Niu , Shih?Ann Chen , and Wen?Chung Yu 1 Department of Medicine Taipei Veterans General Hospital Yuanshan and Suao Branch Yilan Taiwan 2 Division of Cardiology, Department of Medicine Taipei Veterans General Hospital Taipei Taiwan 3 Cardiovascular Research Center National Yang Ming Chiao Tung University Taipei Taiwan 4 Department of Internal Medicine College of Medicine, National Yang Ming Chiao Tung University Taipei Taiwan 5 Department of Biomedical Imaging and Radiological Sciences National Yang Ming (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundA previously underrecognized phenotype of left ventricular apical aneurysm (LVAA) has been increasingly identified in Fabry disease. This study explored LVAA's clinical prevalence and its prognostic (...) (Journal of the American Heart Association)
11:39
Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke - Di Yu, Nuanyi Liang , Julia Zebarth , Qing Shen , Miracle Ozzoude , Maged Goubran , Jennifer S. Rabin , Joel Ramirez , Christopher J. M. Scott , Fuqiang Gao , Robert Bartha , Sean Symons , Seyyed Mohammad Hassan Haddad , Courtney Berezuk , Brian Tan , Donna Kwan , Robert A. Hegele , Allison A. Dilliott , Nuwan D. Nanayakkara , Malcolm A. Binns , Derek Beaton , Stephen R. Arnott , Jane M. Lawrence?Dewar , Ayman Hassan , Dar Dowlatshahi , Jennifer Mandzia , Demetrios Sahlas , Leanne Casaubon , Gustavo Saposnik , Yurika Otoki , Krista L. Lanctôt , Mario Masellis , Sandra E. Black , Richard H. (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundCerebral small vessel disease is associated with higher ratios of soluble?epoxide hydrolase derived linoleic acid diols (12,13?dihydroxyoctadecenoic acid [DiHOME] and 9,10?DiHOME) to their parent epoxides (...) (Journal of the American Heart Association)
11:38
Vessel Patency and Associated Factors of Drug?Coated Balloon for Femoropopliteal Lesion - Yoshimitsu Soga, Mitsuyoshi Takahara , Osamu Iida , Yusuke Tomoi , Daizo Kawasaki , Akiko Tanaka , Yasutaka Yamauchi , Kazuki Tobita , Amane Kozuki , Masahiko Fujihara , Kenji Ando , and 1 Department of Cardiology Kokura Memorial Hospital Kitakyushu Japan 2 Department of Metabolic Medicine Osaka University Graduate School of Medicine Suita Japan 3 Department of Diabetes Care Medicine Osaka University Graduate School of Medicine Suita Japan 4 Kansai Rosai Hospital, Cardiovascular Center Amagasaki Japan 5 Department of Cardiology Morinomiya Hospital Osaka Japan 6 Department of Cardiology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundAlthough clinical trials have reported favorable outcomes after drug?coated balloon (DCB) therapy for femoropopliteal lesions, their real?world performance and predictors have not been well evaluated. This (...) (Journal of the American Heart Association)
11:37
Prediction of Deterioration of Left Ventricular Function Using 3?Dimensional Speckle?Tracking Echocardiography in Patients With Left Bundle?Branch Block - Hyue Mee Kim, In?Chang Hwang , Yeonyee Elizabeth Yoon , Jun?Bean Park , Seung?Pyo Lee , Hyung?Kwan Kim , Yong?Jin Kim , Yaeji Lim , and Goo?Yeong Cho 1 Division of Cardiology Department of Internal Medicine Chung?Ang University Hospital Chung?Ang University College of Medicine Seoul South Korea 2 Cardiovascular Center & Department of Internal Medicine College of Medicine Seoul National University Seoul National University Bundang Hospital Seongnam Gyeonggi South Korea 3 Cardiovascular Center, Department of Internal Medicine College of Medicine, Seoul National University Seoul National (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundPrevious studies have demonstrated that 2?dimensional (2D) global longitudinal strain (GLS) is associated with cardiovascular outcomes in patients with left bundle?branch block. However, the predictive value (...) (Journal of the American Heart Association)
11:32
Femoral Vascular Closure Devices and Bleeding, Hemostasis, and Ambulation Following Percutaneous Coronary Intervention - Guillaume Marquis?Gravel, Laurie?Anne Boivin?Proulx , Zhen Huang , Steven L. Zelenkofske , A. Michael Lincoff , Roxana Mehran , P. Gabriel Steg , Christoph Bode , John H. Alexander , and Thomas J. Povsic 1 Duke Health Duke Clinical Research Institute and Duke University Durham NC 2 Montreal Heart Institute, University of Montreal Montreal QC 3 Regado Biosciences Basking Ridge NJ 4 Cleveland Clinic Coordinating Center for Clinical Research (C5Research) Cleveland OH 5 Icahn School of Medicine at Mount Sinai New York NY 6 Université Paris?Cité Paris France 7 University of Freiburg Freiburg (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe effectiveness of vascular closure devices (VCDs) to reduce bleeding after transfemoral percutaneous coronary intervention remains unsettled.Methods and ResultsParticipants in the REGULATE?PCI (Effect of (...) (Journal of the American Heart Association)

24 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:39
Clinical Associations of Injuries Caused by Vasovagal Syncope: A Cohort Study From a Tertiary Syncope Unit - Masih Tajdini, Hamed Tavolinejad , Arya Aminorroaya , Zahra Aryan , Arash Jalali , Farshid Alaeddini , Saeed Sadeghian , Somayeh Yadangi , Ali Vasheghani?Farahani , Parvin Kalhor , and Ali Bozorgi 1 Tehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran Iran 2 Noncommunicable Disease Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran Iran 3 Department of Medicine Rutgers New Jersey Medical School Newark NY 4 Cardiac Primary Prevention Research Center, Tehran Heart (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundRecent research has revealed that vasovagal syncope (VVS) leads to a high incidence of injuries; however, clinical associations of injury are not well?established. We present data from an ongoing VVS cohort (...) (Journal of the American Heart Association)
11:37
Social Deprivation and Post?TAVR Outcomes in Ontario, Canada: A Population?Based Study - Raumil V. Patel, Mithunan Ravindran , Feng Qiu , Ragavie Manoragavan , Maneesh Sud , Derrick Y. Tam , Mina Madan , Gil Marcus , Gabby Elbaz?Greener , Mamas A. Mamas , and Harindra C. Wijeysundera 1 Temerty Faculty of Medicine University of Toronto Ontario Toronto Canada 2 Institute for Health Policy, Management, and Evaluation Ontario Toronto Canada 3 Institute for Clinical Evaluative Sciences Ontario Toronto Canada 4 Division of Cardiology, Department of Medicine Schulich Heart Program, Sunnybrook Health Sciences Centre Ontario Toronto Canada 5 Division of Cardiac Surgery, Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundTranscatheter aortic valve replacement (TAVR)/intervention has become the standard of care for treatment of severe aortic stenosis across the spectrum of risk. There are socioeconomic disparities in access (...) (Journal of the American Heart Association)
11:36
Association of Cardiovascular Health Score With Early? and Later?Onset Diabetes and With Subsequent Vascular Complications of Diabetes - Yuni Choi, David R. Jacobs , Michael Patrick Bancks , Cora E. Lewis , EunSeok Cha , Fengxia Yan , Mercedes R. Carnethon , Pamela J. Schreiner , and Daniel A. Duprez 1 Division of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN 2 Department of Epidemiology and Prevention Wake Forest School of Medicine Winston?Salem NC 3 Department of Epidemiology University of Alabama at Birmingham Birmingham AL 4 College of Nursing Chungnam National University Daejeon South Korea 5 Nell Hodgson Woodruff School of Nursing Emory University Atlanta GA 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BACKGROUNDLittle attention has been paid to how well the American Heart Association's cardiovascular health (CVH) score predicts early?onset diabetes in young adults. We investigated the association of CVH score with (...) (Journal of the American Heart Association)
11:36
Coronary Slow Flow Is Not Diagnostic of Microvascular Dysfunction in Patients With Angina and Unobstructed Coronary Arteries - Utkarsh Dutta, Aish Sinha , Ozan M. Demir , Howard Ellis , Haseeb Rahman , and Divaka Perera 1 School of Cardiovascular Medicine and Sciences British Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre, King’s College London London UK J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundGuidelines recommend that coronary slow flow phenomenon (CSFP), defined as corrected thrombolysis in myocardial infarction frame count (CTFC)>$$ > $$27, can diagnose coronary microvascular dysfunction (...) (Journal of the American Heart Association)
11:36
Biomarker Concentrations and Their Temporal Changes in Patients With Myocardial Infarction and Nonobstructive Compared With Obstructive Coronary Arteries: Results From the PLATO Trial - Marcus Hjort, Kai M. Eggers , Tatevik Ghukasyan Lakic , Johan Lindbäck , Andrzej Budaj , Jan H. Cornel , Evangelos Giannitsis , Hugo A. Katus , Agneta Siegbahn , Robert F. Storey , Richard C. Becker , Lars Wallentin , Bertil Lindahl , and 1 Department of Medical Sciences Uppsala University Uppsala Sweden 2 Uppsala Clinical Research Center Uppsala University Uppsala Sweden 3 Department of Cardiology, Centre of Postgraduate Medical Education Grochowski Hospital Warsaw Poland 4 Department of Cardiology, Northwest Clinics Alkmaar, and Radboud University Medical Center Nijmegen The Netherlands (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe pathobiology of myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is often uncertain. Investigating biomarker concentrations and their changes may offer novel pathophysiological (...) (Journal of the American Heart Association)
11:35
Proteolytic Degradation Is a Major Contributor to Bioprosthetic Heart Valve Failure - Alexander E. Kostyunin, Tatiana V. Glushkova , Arseniy A. Lobov , Evgeny A. Ovcharenko , Bozhana R. Zainullina , Leo A. Bogdanov , Daria K. Shishkova , Victoria E. Markova , Maksim A. Asanov , Rinat A. Mukhamadiyarov , Elena A. Velikanova , Tatiana N. Akentyeva , Maria A. Rezvova , Alexander N. Stasev , Alexey V. Evtushenko , Leonid S. Barbarash , and Anton G. Kutikhin 1 Department of Experimental Medicine Research Institute for Complex Issues of Cardiovascular Diseases Kemerovo Russian Federation 2 Department of Regenerative Biomedicine Research Institute of Cytology St. Petersburg (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundWhereas the risk factors for structural valve degeneration (SVD) of glutaraldehyde?treated bioprosthetic heart valves (BHVs) are well studied, those responsible for the failure of BHVs fixed with (...) (Journal of the American Heart Association)
11:34
Association of Incidentally Discovered Covert Cerebrovascular Disease Identified Using Natural Language Processing and Future Dementia - David M. Kent, Lester Y. Leung , Yichen Zhou , Patrick H. Luetmer , David F. Kallmes , Jason Nelson , Sunyang Fu , Eric J. Puttock , Chengyi Zheng , Hongfang Liu , and Wansu Chen 1 Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center Boston MA 2 Department of Neurology Tufts Medical Center Boston MA 3 Department of Research and Evaluation Kaiser Permanente Southern California Pasadena CA 4 Department of Radiology Mayo Clinic Rochester MN 5 Department of AI and Informatics Mayo Clinic Rochester (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundCovert cerebrovascular disease (CCD) has been shown to be associated with dementia in population?based studies with magnetic resonance imaging (MRI) screening, but dementia risk associated with incidentally (...) (Journal of the American Heart Association)
11:33
Predicting Arterial Thrombotic Events Following Peripheral Revascularization Using Objective Viscoelastic Data - Monica Majumdar, Ryan P. Hall , Zachary Feldman , Guillaume Goudot , Natalie Sumetsky , Samuel Jessula , Amanda Kirshkaln , Tiffany Bellomo , David Chang , Jessica Cardenas , Rushad Patell , Matthew Eagleton , and Anahita Dua 1 Division of Vascular and Endovascular Surgery, Department of Surgery Massachusetts General Hospital/Harvard Medical School Boston MA 2 Cardiovascular Research Center, Division of Cardiology Massachusetts General Hospital/Harvard Medical School Boston MA 3 Department of Epidemiology and Statistics University of Pittsburg PA 4 Healthcare Research and Policy (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundPeripheral artery disease is endemic in our globally aging population, with >200 million affected worldwide. Graft/stent thrombosis after revascularization is common and frequently results in amputation, (...) (Journal of the American Heart Association)
11:33
Transfusion Thresholds for Acute Coronary Syndromes—Insights From the TRICS?III Randomized Controlled Trial, Systematic Review, and Meta?Analysis - Nikhil Mistry, Gregory M. T. Hare , Nadine Shehata , Emilie Belley?Cote , Fabio Papa , Robert S. Kramer , Tarit Saha , Duminda N. Wijeysundera , Dennis Ko , Subodh Verma , and C. David Mazer 1 Department of Anesthesia St. Michael’s Hospital Toronto Ontario Canada 2 Institute of Medical Sciences University of Toronto Ontario 3 Department of Anesthesiology and Pain Medicine University of Toronto Ontario Canada 4 Department of Physiology University of Toronto Ontario Canada 5 Li Ka Shing Knowledge Institute of St. Michael’s Hospital Toronto Ontario Canada 6 Division of Hematology Sinai Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:33
Lipid?Lowering Trials Are Not Representative of Patients Managed in Clinical Practice: A Systematic Review and Meta?Analysis of Exclusion Criteria - Martina Aeschbacher?Germann, Nathalie Kaiser , Alexandre Speierer , Manuel R. Blum , Douglas C. Bauer , Cinzia Del Giovane , Drahomir Aujesky , Baris Gencer , Nicolas Rodondi , and Elisavet Moutzouri 1 Department of General Internal Medicine, Inselspital Bern University Hospital, University of Bern Switzerland 2 Institute of Primary Health Care (BIHAM) University of Bern Switzerland 3 Departments of Medicine and Epidemiology and Biostatistics University of California San Francisco CA 4 Division of Cardiology Geneva University Hospitals Geneva (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundRandomized clinical trials (RCTs) might not be representative of the real?world population because of unreasonable exclusion criteria. We sought to determine which groups of patients are excluded from RCTs (...) (Journal of the American Heart Association)
11:32
Elevated Homocysteine Intensify the Effect of Lipoprotein(a) on Stroke Recurrence - Zhiyuan Feng, Jie Xu , Aoming Jin , Aichun Cheng , Jing Xue , Xia Meng , and Yongjun Wang 1 Department of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China 2 China National Clinical Research Center for Neurological Diseases, Tiantan Hospital, Advanced Innovation Center for Human Brain Protection Capital Medical University Beijing China 3 Clinical Center for Precision Medicine in Stroke Capital Medical University Beijing (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:32
Characterization of Atrial Substrate to Predict the Success of Pulmonary Vein Isolation: The Prospective, Multicenter MASH?AF II (Multipolar Atrial Substrate High Density Mapping in Atrial Fibrillation) Study - Marco Bergonti, Francesco Raffaele Spera , Teba Gonzalez Ferrero , Michelle Nsahlai , Alice Bonomi , Maxime Tijskens , Wim Boris , Johan Saenen , Wim Huybrechts , Hielko Miljoen , Jose Ramón González?Juanatey , Jose Luis Martínez?Sande , Lien Vandaele , Anouk Wittock , Hein Heidbuchel , Miguel Valderrábano , Moises Rodríguez?Mañero , and Andrea Sarkozy 1 Department of Cardiology University Hospital Antwerp Antwerp Belgium 2 Complexo Hospitalario Universitario de Santiago de Compostela (CHUS) SERGAS Santiago de Compostela Spain 3 Department of Cardiology DeBakey Heart and Vascular Center, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundLeft atrial substrate may have mechanistic relevance for ablation of atrial fibrillation (AF). We sought to analyze the relationship between low?voltage zones (LVZs), transition zones, and AF recurrence in (...) (Journal of the American Heart Association)
11:32
Disparate Cardiovascular Hospitalization Trends Among Young and Middle?Aged Adults Within and Across Race and Ethnicity Groups in Four States in the United States - Ehimare Akhabue, Melanie Rua , Poonam Gandhi , Jung Hyun Kim , Joel C. Cantor , and Soko Setoguchi 1 Division of Cardiovascular Diseases and Hypertension, Department of Medicine Rutgers Robert Wood Johnson Medical School New Brunswick NJ 2 Institute for Health, Health Care Policy and Aging Research, Rutgers University New Brunswick NJ 3 Department of Preventive Medicine Yonsei University College of Medicine Seoul Republic of Korea 4 Department of Medicine Rutgers Robert Wood Johnson Medical School New Brunswick (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundInpatient hospitalizations for cardiovascular disease (CVD) decreased nationally in the past decade. However, data are lacking on whether national declines represent trends within and across race and (...) (Journal of the American Heart Association)
11:32
Ross Procedure Versus Mechanical Versus Bioprosthetic Aortic Valve Replacement: A Network Meta?Analysis - Yujiro Yokoyama, Toshiki Kuno , Nana Toyoda , Tomohiro Fujisaki , Hisato Takagi , Shinobu Itagaki , Michael Ibrahim , Maral Ouzounian , Ismail El?Hamamsy , and Shinichi Fukuhara 1 Department of Surgery St. Luke’s University Health Network Bethlehem PA 2 Department of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine New York NY 3 Department of Cardiovascular Surgery Icahn School of Medicine at Mount Sinai New York NY 4 Department of Medicine Icahn School of Medicine at Mount Sinai, Mount Sinai Morningside and West New York NY 5 Department of Cardiovascular Surgery (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe Ross operation appears to restore normal survival in young and middle?aged adults with aortic valve disease. However, there are limited data comparing it with conventional aortic valve replacement. (...) (Journal of the American Heart Association)
11:30
Lifetime Burden of Morbidity in Patients With Isolated Congenital Ventricular Septal Defect - Filip Eckerström, Camilla Nyboe , Andrew Redington , and Vibeke Elisabeth Hjortdal 1 Department of Cardiothoracic Surgery Copenhagen University Hospital Copenhagen Denmark 2 Department of Clinical Medicine Copenhagen University Hospital Copenhagen Denmark 3 Department of Cardiothoracic and Vascular Surgery Aarhus University Hospital Aarhus Denmark 4 Department of Clinical Medicine Aarhus University Aarhus Denmark 5 The Heart Institute, Cincinnati Children’s Hospital Medical Center Cincinnati Ohio (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe lifetime burden of morbidity in patients with isolated congenital ventricular septal defect (VSD) is not completely described.Methods and ResultsIn a population?based cohort study in Denmark using (...) (Journal of the American Heart Association)
11:30
Shrunken Pore Syndrome: A New and More Powerful Phenotype of Renal Dysfunction Than Chronic Kidney Disease for Predicting Contrast?Associated Acute Kidney Injury - Li?Wei Zhang, Man?Qing Luo , Xian?Wei Xie , Zhe?Bin You , Ji?Lang Zeng , Mao?Qing Lin , Li?Chuan Chen , Kai?Yang Lin , and Yan?Song Guo 1 Department of Cardiology Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital Fuzhou China 2 Fujian Provincial Key Laboratory of Cardiovascular Disease, Fujian Provincial Center for Geriatrics Fujian Provincial Clinical Research Center for Severe Acute Cardiovascular Diseases Fuzhou China 3 Fujian Heart Failure Center Alliance Fuzhou China 4 Fujian Key Laboratory of Geriatrics, Department of Geriatric Medicine, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundShrunken pore syndrome (SPS) as a novel phenotype of renal dysfunction is characterized by a difference in renal filtration between cystatin C and creatinine. The manifestation of SPS was defined as a (...) (Journal of the American Heart Association)
11:29
Inflammation and Incident Conduction Disease - Emilie K. Frimodt?Møller, John S. Gottdiener , Elsayed Z. Soliman , Jorge R. Kizer , Eric Vittinghoff , Bruce M. Psaty , Tor Biering?Sørensen , and Gregory M. Marcus 1 Division of Cardiology University of California San Francisco CA 2 Department of Cardiology Herlev and Gentofte Hospital, University of Copenhagen Denmark 3 Division of Cardiology University of Maryland Baltimore MD 4 Department of Cardiovascular Medicine Wake Forest School of Medicine Winston?Salem NC 5 Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Systems and Population Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:36
Lipoprotein Subclasses Associated With High?Risk Coronary Atherosclerotic Plaque: Insights From the PROMISE Clinical Trial - Robert W. McGarrah, Maros Ferencik , Stephanie N. Giamberardino , Udo Hoffmann , Borek Foldyna , Julia Karady , Geoffrey S. Ginsburg , William E. Kraus , Pamela S. Douglas , and Svati H. Shah 1 Division of Cardiology, Department of Medicine Duke University School of Medicine Durham NC 2 Duke Molecular Physiology Institute Duke University School of Medicine Durham NC 3 Knight Cardiovascular Institute Oregon Health and Science University Portland OR 4 Cardiovascular Imaging Research Center Harvard Medical School–Massachusetts General Hospital Boston MA 5 MTA?SE Cardiovascular Imaging (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BACKGROUNDMore than half of major adverse cardiovascular events (MACE) occur in the absence of obstructive coronary artery disease and are often attributed to the rupture of high?risk coronary atherosclerotic plaque (...) (Journal of the American Heart Association)
11:36
Initial Antihypertensive Regimens in Newly Treated Patients: Real World Evidence From the OneFlorida+ Clinical Research Network - Steven M. Smith, Almut G. Winterstein , Matthew J. Gurka , Marta G. Walsh , Shailina Keshwani , Anne M. Libby , William R. Hogan , Carl J. Pepine , and Rhonda M. Cooper?DeHoff 1 Department of Pharmaceutical Outcomes and Policy, College of Pharmacy University of Florida Gainesville FL 2 Division of Cardiovascular Medicine, Department of Medicine, College of Medicine University of Florida Gainesville FL 3 Center for Integrative Cardiovascular and Metabolic Disease University of Florida Gainesville FL 4 Department of Health Outcomes and Biomedical Informatics, College of Medicine University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundKnowledge of real?world antihypertensive use is limited to prevalent hypertension, limiting our understanding of how treatment evolves and its contribution to persistently poor blood pressure control. We (...) (Journal of the American Heart Association)
11:35
Cardiovascular Risk Factors and Risk of Alzheimer Disease and Mortality: A Latent Class Approach - Myuri Ruthirakuhan, Hugo Cogo?Moreira , Walter Swardfager , Nathan Herrmann , Krista L. Lanctot , and Sandra E. Black 1 Hurvitz Brain Sciences Research Program Sunnybrook Research Institute Toronto Ontario Canada 2 University of Toronto Toronto Ontario Canada 3 Department of Education, ICT and Learning Ostfold University College Halden Norway 4 Universidade Federal de Sao Paulo Sao Paulo Brazil J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundCardiovascular risk factors co?occur with one another, and little is known about the extent of their clustering and risk of Alzheimer disease (AD). We identify groups of cardiovascular risk factors in (...) (Journal of the American Heart Association)
11:35
Protective Role of Endothelial Fibulin?4 in Valvulo?Arterial Integrity - Tram Anh Vu Nguyen, Caroline Antunes Lino , Huynh Thuy Hang , Juliano Vilela Alves , Bui Quoc Thang , Seung Jae Shin , Kaori Sugiyama , Hiroko Matsunaga , Haruko Takeyama , Yoshito Yamashiro , and Hiromi Yanagisawa 1 Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance University of Tsukuba Ibaraki Japan 2 Ph.D. Program in Human Biology, School of Integrative and Global Majors University of Tsukuba Ibaraki Japan 3 Department of Anatomy University of Sao Paulo, Institute of Biomedical Sciences Sao Paulo Brazil 4 Graduate School of Comprehensive Human Sciences (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundHomeostasis of the vessel wall is cooperatively maintained by endothelial cells (ECs), smooth muscle cells, and adventitial fibroblasts. The genetic deletion of fibulin?4 (Fbln4) in smooth muscle cells (...) (Journal of the American Heart Association)
11:34
Impact of Empagliflozin in Heart Failure With Reduced Ejection Fraction in Patients With Ischemic Versus Nonischemic Cause - Muhammad Shahzeb Khan, Javed Butler , Stefan D. Anker , Gerasimos Filippatos , João Pedro Ferreira , Stuart J. Pocock , James L. Januzzi , Ileana L. Piña , Michael Böhm , Piotr Ponikowski , Subodh Verma , Martina Brueckmann , Ola Vedin , Cordula Zeller , Faiez Zannad , and Milton Packer 1 Division of Cardiology Duke University School of Medicine Durham NC 2 Baylor Scott and White Research Institute Dallas TX 3 Department of Medicine University of Mississippi School of Medicine Jackson MS 4 Department of Cardiology (CVK) Berlin Institute of Health Center for Regenerative Therapies (BCRT), (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundOutcomes and treatment effects of therapy may vary according to the cause of heart failure (HF).Methods and ResultsIn this post hoc analysis of the EMPEROR?Reduced (Empagliflozin Outcome Trial in Patients (...) (Journal of the American Heart Association)
11:34
Impact of Race and Ethnicity on Use and Outcomes of Septal Reduction Therapies for Obstructive Hypertrophic Cardiomyopathy - Sri Harsha Patlolla, Hartzell V. Schaff , Rick A. Nishimura , Mackram F. Eleid , Jeffrey B. Geske , and Steve R. Ommen 1 Department of Cardiovascular Surgery Mayo Clinic Rochester MN 2 Department of Cardiovascular Medicine Mayo Clinic Rochester MN J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundInformation on impact of race and ethnicity on use and early outcomes of septal reduction therapies (SRTs) for obstructive hypertrophic obstructive cardiomyopathy are limited.Methods and ResultsUsing the (...) (Journal of the American Heart Association)
11:33
Combination of Neutrophil?to?Lymphocyte and Platelet?to?Lymphocyte Ratios as a Novel Predictor of Cardiac Death in Patients With Acute Decompensated Heart Failure With Preserved Left Ventricular Ejection Fraction: A Multicenter Study - Shunsuke Tamaki, Yoshiyuki Nagai , Ryu Shutta , Daisaku Masuda , Shizuya Yamashita , Masahiro Seo , Takahisa Yamada , Akito Nakagawa , Yoshio Yasumura , Yusuke Nakagawa , Masamichi Yano , Takaharu Hayashi , Shungo Hikoso , Daisaku Nakatani , Yohei Sotomi , Yasushi Sakata , and 1 Department of Cardiology Rinku General Medical Center Osaka Japan 2 Division of Cardiology Osaka General Medical Center Osaka Japan 3 Division of Cardiology Amagasaki Chuo Hospital Amagasaki Japan 4 Department of Medical Informatics Osaka University Graduate School of Medicine Osaka Japan 5 Division of Cardiology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundNeutrophil?to?lymphocyte ratio (NLR) and platelet?to?lymphocyte ratio (PLR) are novel inflammation markers. Their combined usefulness for estimating the prognosis of patients with heart failure with preserved (...) (Journal of the American Heart Association)
11:33
Epicardial Fat Volume, Cardiac Function, and Incident Heart Failure: The Rotterdam Study - Banafsheh Arshi, Hamid A. Aliahmad , M. Arfan Ikram , Daniel Bos , and Maryam Kavousi 1 Department of Epidemiology, Erasmus MC University Medical Center Rotterdam The Netherlands 2 Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center Rotterdam The Netherlands J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundLarger epicardial fat volume (EFV) has been associated with increased risks of cardiovascular disease and atrial fibrillation. Yet, evidence on the association of EFV with cardiac function and incident (...) (Journal of the American Heart Association)
11:32
On?Treatment Platelet Reactivity and Ischemic Outcomes in Patients With Diabetes Mellitus: Two?Year Results From ADAPT?DES - Bahira Shahim, Björn Redfors , Thomas D. Stuckey , Mengdan Liu , Zhipeng Zhou , Bernhard Witzenbichler , Giora Weisz , Michael J. Rinaldi , Franz?Josef Neumann , D. Christopher Metzger , Timothy D. Henry , David A. Cox , Peter L. Duffy , Bruce R. Brodie , Iva Srdanovic , Mahesh V. Madhavan , Ernest L. Mazzaferri , Roxana Mehran , Ori Ben?Yehuda , Ajay J. Kirtane , and Gregg W. Stone 1 Clinical Trials Center Cardiovascular Research Foundation New York NY 2 Deparment of Medicine Karolinska Institutet Stockholm Sweden 3 Cardiology Unit, Karolinska University Hospital Karolinska Institutet (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundDiabetes mellitus and high platelet reactivity (HPR) on clopidogrel are both associated with increased risk of ischemic events after percutaneous coronary intervention, but whether the HPR?associated risk (...) (Journal of the American Heart Association)
11:31
Occult Diastolic Dysfunction and Adverse Clinical Outcomes in Adolescents and Young Adults With Fontan Circulation - Daniel Peck, Konstantin Averin , Philip Khoury , Grant Veldhuis , Tarek Alsaied , Adam M. Lubert , Russel Hirsch , Wendy M. Whiteside , Gruschen Veldtman , and Bryan H. Goldstein 1 The Heart Institute, Cincinnati Children’s Hospital Medical Center Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH 2 Division of Cardiology, Department of Pediatrics University of Alberta Edmonton AB 3 Heart Institute, UPMC Children’s Hospital of Pittsburgh Department of Pediatrics University of Pittsburgh School of Medicine Pittsburgh PA 4 Congenital Heart Center University of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundIn Fontan circulation, diastolic dysfunction portends a worse clinical outcome but may be concealed during routine assessment. Invasive evaluation with rapid volume expansion (RVE) can identify patients (...) (Journal of the American Heart Association)
11:31
Long?Term Clinical Outcomes in Patients With Severe Tricuspid Regurgitation - Naoki Nishiura, Takeshi Kitai , Taiji Okada , Madoka Sano , Norihisa Miyawaki , Kitae Kim , Ryosuke Murai , Toshiaki Toyota , Yasuhiro Sasaki , Natsuhiko Ehara , Atsushi Kobori , Makoto Kinoshita , Tadaaki Koyama , and Yutaka Furukawa 1 Department of Cardiovascular Medicine Kobe City Medical Center General Hospital Kobe Japan 2 Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center Osaka Japan 3 Department of Cardiothoracic Surgery Kobe City Medical Center General Hospital Kobe (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe natural history and optimal interventional timing in patients with isolated severe tricuspid regurgitation (TR) have not been well studied. This study aimed to investigate long?term clinical outcomes (...) (Journal of the American Heart Association)
11:30
Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population - Tan Lai Zhou, Monica T. J. Schütten , Abraham A. Kroon , Ronald M. A. Henry , Alfonsius J. H. M. Houben , Carla J. H. van der Kallen , Marleen M. J. van Greevenbroek , Peter W. de Leeuw , and Coen D. A. Stehouwer 1 Department of Internal Medicine Maastricht University Medical Center+ Maastricht The Netherlands 2 Cardiovascular Research Institute Maastricht (CARIM) Maastricht University Maastricht The Netherlands 3 Heart and Vascular Center Maastricht University Medical Center+ Maastricht The (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundSalt restriction may lower blood pressure variability (BPV), but previous studies have shown inconsistent results. Therefore, we investigated in an observational study and intervention trial whether (...) (Journal of the American Heart Association)
11:29
Interaction of Blood Pressure and Glycemic Status in Developing Cardiovascular Disease: Analysis of a Nationwide Real?World Database - Yuta Suzuki, Hidehiro Kaneko , Yuichiro Yano , Akira Okada , Hidetaka Itoh , Satoshi Matsuoka , Isao Yokota , Takahiro Imaizumi , Katsuhito Fujiu , Nobuaki Michihata , Taisuke Jo , Norifumi Takeda , Hiroyuki Morita , Koichi Node , Hideo Yasunaga , and Issei Komuro 1 The Department of Cardiovascular Medicine The University of Tokyo Tokyo Japan 2 Center for Outcomes Research and Economic Evaluation for Health National Institute of Public Health Saitama Japan 3 The Department of Advanced Cardiology The University of Tokyo Tokyo Japan 4 Department of Advanced Epidemiology, NCD Epidemiology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundHypertension and diabetes frequently coexist. However, little is known about the interaction between high blood pressure (BP) and hyperglycemia in the development of cardiovascular disease (CVD).Methods (...) (Journal of the American Heart Association)

21 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

08:02
Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People With and Without Hypertension - Masayuki Teramoto, Kazumasa Yamagishi , Isao Muraki , Akiko Tamakoshi , and Hiroyasu Iso 1 Department of Social Medicine Osaka University Graduate School of Medicine Osaka Japan 2 Institute for Global Health Policy Research, Bureau of International Health Cooperation National Center for Global Health and Medicine Tokyo Japan 3 Department of Epidemiology and Biostatistics University of California San Francisco CA 4 Department of Public Health Medicine, Faculty of Medicine, and Health Services Research and Development Center University of Tsukuba Tsukuba Japan 5 Department of Public Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 2, January 17, 2023. BackgroundThis study was conducted to examine the impacts of coffee and green tea consumption on cardiovascular disease (CVD) mortality among people with severe hypertension.Methods and ResultsIn the JACC (Japan (...) (Journal of the American Heart Association)

20 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:41
Emergency Medical Services Stroke Care Performance Variability in Michigan: Analysis of a Statewide Linked Stroke Registry - J. Adam Oostema, Adrienne Nickles , Zhehui Luo , and Mathew J. Reeves 1 Department of Emergency Medicine Michigan State University College of Human Medicine, Secchia Center Grand Rapids MI 2 Michigan Department of Health and Human Services, Lifecourse Epidemiology and Genomics Division Lansing MI 3 Department of Epidemiology and Biostatistics Michigan State University College of Human Medicine East Lansing MI J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundEmergency medical services (EMS) compliance with recommended prehospital care for patients with acute stroke is inconsistent; however, sources of variability in compliance are not well understood. The (...) (Journal of the American Heart Association)
11:41
Emergency Medical Services Data: An Unexpected Source of Variation in Stroke Care Performance - Rebecca E. Cash, and Christopher T. Richards 1 Department of Emergency Medicine Massachusetts General Hospital, Harvard Medical School Boston MA 2 Division of Emergency Medical Services, Department of Emergency Medicine University of Cincinnati College of Medicine Cincinnati OH J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:40
A Potential New Link Between Inflammation and Vascular Calcification - Xinjiang Cai, Yin Tintut , and Linda L. Demer 1 Department of Medicine University of California, Los Angeles (UCLA) Los Angeles CA 2 Department of Bioengineering University of California, Los Angeles (UCLA) Los Angeles CA 3 Department of Physiology University of California Los Angeles CA 4 Department of Orthopaedic Surgery University of California Los Angeles CA 5 VA Greater Los Angeles Healthcare System Los Angeles CA J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. (Journal of the American Heart Association)
11:40
Interleukin?29 Accelerates Vascular Calcification via JAK2/STAT3/BMP2 Signaling - Nannan Hao, Zihao Zhou , Feifei Zhang , Yong Li , Rui Hu , Junjie Zou , Rui Zheng , Lei Wang , Lingxiao Xu , Wenfeng Tan , Chunjian Li , and Fang Wang 1 Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu Province China 2 Department of Vascular Surgery The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu Province China 3 Department of Cardiovascular Surgery The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu Province China 4 Department of Rheumatology The First Affiliated Hospital of Nanjing (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundVascular calcification (VC), associated with enhanced cardiovascular morbidity and mortality, is characterized by the osteogenic transdifferentiation of vascular smooth muscle cells. Inflammation promotes (...) (Journal of the American Heart Association)

19 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:02
Nitrites, Nitrates, and Cardiovascular Outcomes: Are We Living “La Vie en Rose” With Pink Processed Meats? - Bernard Srour, Eloi Chazelas , Léopold K. Fezeu , Guillaume Javaux , Fabrice Pierre , Inge Huybrechts , Serge Hercberg , Mélanie Deschasaux?Tanguy , Emmanuelle Kesse?Guyot , and Mathilde Touvier 1 Sorbonne Paris Nord University, Inserm U1153, Inrae U1125, Cnam, Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center – University of Paris?Cité (CRESS) Bobigny France 2 Nutrition And Cancer Research Network (NACRe Network) Jouy?en?Josas France 3 Toxalim (Research Centre in Food Toxicology) Université de Toulouse, INRAE, ENVT, INP?Purpan, UPS Toulouse France 4 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundNitrates and nitrites are used as food additives in processed meats. They are also commonly ingested from water and several foods. Several short?term clinical studies suggested beneficial effects of (...) (Journal of the American Heart Association)
12:01
Endovascular Treatment for Minor Acute Ischemic Strokes With Large Vessel Occlusion - Rui Xue, Wansi Zhong , Ying Zhou , Yaode He , Shenqiang Yan , Zhicai Chen , Jianan Wang , Xiaoxian Gong , and Min Lou 1 Department of Neurology The Second Affiliated Hospital of Zhejiang University, School of Medicine Hangzhou China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundIt remains uncertain whether patients with minor acute ischemic stroke with large vessel occlusion benefit from endovascular treatment (EVT). We aim to evaluate the outcomes of EVT in minor acute (...) (Journal of the American Heart Association)
12:01
Climate Change and Cardiovascular Health - William W. Aitken, Scott C. Brown , and Alejandro P. Comellas 1 Division of Cardiology, Department of Medicine University of Miami Miller School of Medicine Miami FL 2 Department of Public Health Sciences University of Miami School of Architecture Coral Gables FL 3 Division of Pulmonary, Critical Care, and Occupational Medicine University of Iowa Iowa City IA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. (Journal of the American Heart Association)
12:01
Brain Enlarged Perivascular Spaces as Imaging Biomarkers of Cerebrovascular Disease: A Clinical Narrative Review - Srinath Ramaswamy, Farid Khasiyev , and Jose Gutierrez 1 Department of Neurology SUNY Downstate Health Sciences University Brooklyn NY 2 Department of Neurology St. Louis University School of Medicine St. Louis MO 3 Department of Neurology Columbia University Irving Medical Center New York NY J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. ABSTRACT: Perivascular spaces or Virchow?Robin spaces form pathways along the subarachnoid spaces that facilitate the effective clearance of brain metabolic by?products through intracellular exchange and drainage (...) (Journal of the American Heart Association)
12:00
N?nitrosodimethylamine?Contaminated Valsartan and Risk of Cancer: A Nationwide Study of 1.4 Million Valsartan Users - Imène Mansouri, Jeremie Botton , Laura Semenzato , Nadia Haddy , and Mahmoud Zureik 1 EPI?PHARE (French National Agency for Medicines and Health Products Safety [ANSM] and French National Health Insurance [CNAM]) Saint?Denis France 2 Center for Research Epidemiology and Population Health (CESP), Radiation Epidemiology Team Université Paris?Saclay, Université Paris?Sud, UVSQ Villejuif France 3 Faculté de Pharmacie Université Paris?Saclay Châtenay?Malabry France 4 Anti Infective Evasion and Pharmacoepidemiology Center for Research Epidemiology and Population Health (CESP) Montigny?le?Bretonneu (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundSince July 2018, numerous lots of valsartan have been found to be contaminated withN?nitrosodimethylamine (NDMA). We aimed to assess the association between exposure to valsartan products contaminated (...) (Journal of the American Heart Association)
12:00
Depression and Anxiety Are Associated With Cardiovascular Health in Young Adults - Sierra L. Patterson, Michele Marcus , Margarethe Goetz , Viola Vaccarino , and Holly C. Gooding 1 Department of Epidemiology University of North Carolina at Chapel Hill Chapel Hill NC 2 Department of Epidemiology Rollins School of Public Health Atlanta GA 3 Department of Environmental Health Rollins School of Public Health Atlanta GA 4 Department of Neurology Duke University Durham NC 5 Department of Pediatrics Emory University School of Medicine Atlanta GA United States 6 Children’s Healthcare of Atlanta Atlanta (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundCardiovascular health (CVH) declines in young adulthood, and mood disorders commonly emerge during this life stage. This study examined the association between depression, anxiety, and CVH metrics among (...) (Journal of the American Heart Association)
11:57
Repurposing a Drug Targeting Inflammatory Bowel Disease for Lowering Hypertension - Xue Mei, Blair Mell , Ishan Manandhar , Sachin Aryal , Ramakumar Tummala , Jun Kyoung , Tao Yang , and Bina Joe 1 Program in Physiological Genomics, Center for Hypertension and Precision Medicine, Department of Physiology and Pharmacology, College of Medicine and Life Sciences University of Toledo OH J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThe gut and gut microbiota, which were previously neglected in blood pressure regulation, are becoming increasingly recognized as factors contributing to hypertension. Diseases affecting the gut such as (...) (Journal of the American Heart Association)
11:56
Attendance at Supervised Exercise Sessions and Walking Outcomes in Peripheral Artery Disease: Results From 2 Randomized Clinical Trials - Michael M. Hammond, Lu Tian , Lihui Zhao , Dongxue Zhang , and Mary M. McDermott 1 Feinberg School of Medicine Northwestern University Chicago IL 2 Department of Biomedical Data Science Stanford University Palo Alto CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundSupervised exercise therapy (SET) is the first?line therapy for walking impairment in peripheral artery disease (PAD). This study evaluated the association between attendance at SET and improved walking (...) (Journal of the American Heart Association)
11:56
PVECs?Derived Exosomal microRNAs Regulate PASMCs via FoxM1 Signaling in IUGR?induced Pulmonary Hypertension - Xiaofei Luo, Chengcheng Hang , Ziming Zhang , Kaixing Le , Yuhan Ying , Ying Lv , Lingling Yan , Yajie Huang , Lixia Ye , Xuefeng Xu , Ying Zhong , and Lizhong Du 1 Department of Neonatology, The Children’s Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou Zhejiang Province People’s Republic of China 2 Department of Pediatric Health Care, The Children’s Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou Zhejiang Province People’s Republic of China 3 Department of Rheumatology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundIntrauterine growth restriction (IUGR) is closely related to systemic or pulmonary hypertension (PH) in adulthood. Aberrant crosstalk between pulmonary vascular endothelial cells (PVECs) and pulmonary (...) (Journal of the American Heart Association)
11:55
Cross?Sectional Relationships of Proximal Aortic Stiffness and Left Ventricular Diastolic Function in Adults in the Community - Nicholas Spetko, Jian Rong , Martin G. Larson , Michael Haidar , Inbar Raber , Kevin Peters , Emelia J. Benjamin , Christopher J. O'Donnell , Warren J. Manning , Ramachandran S. Vasan , Gary F. Mitchell , and Connie W. Tsao 1 Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center Harvard Medical School Boston MA 2 Boston University and National Heart, Blood and Lung Institute’s Framingham Heart Study Framingham MA 3 Department of Mathematics and Statistics Boston University Boston MA 4 Tufts University School of Medicine Boston MA 5 Sections of Preventive (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundStiffness of the proximal aorta may play a critical role in adverse left ventricular (LV)–vascular interactions and associated LV diastolic dysfunction. In a community?based sample, we sought to determine (...) (Journal of the American Heart Association)
11:55
Match Outcomes for Cardiovascular Disease Fellowship Training: 2010 to 2021 - Jason Silvestre, Ahmed Brgdar , and Horace M. DeLisser 1 Perelman School of Medicine Philadelphia PA 2 Howard University College of Medicine Washington DC J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThis study elucidates recent trends in application and match rates in the Cardiovascular Disease Fellowship Match. We hypothesized that (1) match rates have increased with time; (2) match rates are (...) (Journal of the American Heart Association)
11:55
Risk and Subtypes of Stroke Following New?Onset Postoperative Atrial Fibrillation in Coronary Bypass Surgery: A Population?Based Cohort Study - Louise Feilberg Rasmussen, Jan J. Andreasen , Sam Riahi , Søren Lundbye?Christensen , Søren P. Johnsen , Grethe Andersen , and Janne K. Mortensen 1 Department of Cardiothoracic Surgery Aalborg University Hospital Aalborg Denmark 2 Department of Clinical Medicine Aalborg University Aalborg Denmark 3 Atrial Fibrillation Study Group Aalborg University Hospital Aalborg Denmark 4 Department of Cardiology Aalborg University Hospital Aalborg Denmark 5 Unit of Clinical Biostatistics Aalborg University Hospital Aalborg Denmark 6 Danish Center for Clinical Health Services Research Aalborg University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundNew?onset postoperative atrial fibrillation (POAF) develops in approximately one?third of patients undergoing cardiac surgery and is associated with a higher incidence of ischemic stroke and increased (...) (Journal of the American Heart Association)
11:55
Racial and Ethnic Disparities in Aortic Stenosis - Puja B. Parikh, and Smadar Kort 1 Division of Cardiovascular Medicine, Department of Medicine Stony Brook University Renaissance School of Medicine Stony Brook NY J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. (Journal of the American Heart Association)
11:54
Outcomes Following Plaque Erosion?Based Acute Coronary Syndromes Treated Without Stenting: The Plaque Matters - Alessandro Maino, and Farouc A. Jaffer 1 Department of Cardiovascular and Pneumological Sciences Catholic University of the Sacred Heart Rome Italy 2 Division of Cardiology Massachusetts General Hospital, Harvard Medical School Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. (Journal of the American Heart Association)
11:54
Valve?in?Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement for Failed Surgical Aortic Bioprostheses: A Systematic Review and Meta?Analysis - Matthias Raschpichler, Suzanne de Waha , David Holzhey , Guido Schwarzer , Nir Flint , Danon Kaewkes , Paul T. Bräuchle , Danny Dvir , Raj Makkar , Gorav Ailawadi , Mohamed Abdel?Wahab , Holger Thiele , and Michael A. Borger 1 Heart Center Leipzig at University of Leipzig Department of Cardiac Surgery Leipzig Germany 2 Smidt Heart Institute Department of Interventional Cardiology, Cedars?Sinai Medical Center Los Angeles CA 3 Department of Cardiac Surgery University Hospital Wuppertal Wuppertal Germany 4 Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundIn the absence of randomized controlled trials, reports from nonrandomized studies comparing valve?in?valve implantation (ViV) to redo surgical aortic valve replacement (rAVR) have shown inconsistent (...) (Journal of the American Heart Association)
11:53
All Models Are Right But Some Are More Useful - Edward Koifman, and Ela Giladi 1 Department of Cardiology Meir Medical Center Kfar?Saba Israel 2 Faculty of Medicine Tel Aviv University Tel Aviv Israel J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. (Journal of the American Heart Association)
11:53
Racial and Ethnic Differences in the Clinical Diagnosis of Aortic Stenosis - Daniela R. Crousillat, Daniel K. Amponsah , Alexander Camacho , Ritvik R. Kandanelly , Devavrat Bapat , Chen Chen , Alexandra Selberg , Ayman Shaqdan , Varsha K. Tanguturi , Michael H. Picard , Judy W. Hung , and Sammy Elmariah 1 Cardiology Division, Massachusetts General Hospital Harvard Medical School Boston MA 2 Division of Cardiovascular Sciences University of South Florida Tampa FL 3 Department of Medicine, Massachusetts General Hospital Harvard Medical School Boston MA 4 Cardiology Division University of California San Francisco San Francisco (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundRacial and ethnic minority groups are underrepresented among patients undergoing aortic valve replacement in the United States. We evaluated the impact of race and ethnicity on the diagnosis of aortic (...) (Journal of the American Heart Association)
11:53
Performance of the American Heart Association/American College of Cardiology Guideline?Recommended Pretest Probability Model for the Diagnosis of Obstructive Coronary Artery Disease - Simon Winther, Theodore Murphy , Samuel Emil Schmidt , Jeroen J. Bax , William Wijns , Juhani Knuuti , and Morten Bøttcher 1 Department of Cardiology Gødstrup Hospital Herning Denmark 2 Barts Heart Centre, St Bartholomew’s Hospital, Barts Health National Health Service (NHS) Trust London United Kingdom 3 Department of Health Science and Technology Aalborg University Aalborg Øst Denmark 4 Heart Center Turku University Hsopital and University of Turku Turku Finland 5 Department of Cardiology Leiden University Medical Center Leiden The Netherlands 6 The Lambe Institute for Translational Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundSubstantial differences exist between different guideline?recommended pretest probability (PTP) models for the detection of obstructive coronary artery disease (CAD). This study was performed to study (...) (Journal of the American Heart Association)
11:53
Predictors of Adverse Prognosis in Patients With Acute Coronary Syndrome Caused by Plaque Erosion With a Nonstent Strategy - Yanwei Yin, Fangmeng Lei , Chao Fang , Senqing Jiang , Xueming Xu , Sibo Sun , Xueying Pei , Ruyi Jia , Caiying Tang , Cong Peng , Song Li , Lulu Li , Yini Wang , Huai Yu , Jiannan Dai , and Bo Yu 1 Department of Cardiology Second Affiliated Hospital of Harbin Medical University, The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education Harbin China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThe EROSION (Effective Anti?Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography?Based Management in Plaque Erosion) study demonstrated that antithrombotic therapy without (...) (Journal of the American Heart Association)

14 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:27
Prior Myocardial Infarction and Treatment Effect of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndromes ? A Post?hoc Analysis of the ISAR?REACT 5 Trial - Shqipdona Lahu, Maria Scalamogna , Gjin Ndrepepa , Maurizio Menichelli , Christian Valina , Rayyan Hemetsberger , Bernhard Witzenbichler , Isabell Bernlochner , Michael Joner , Erion Xhepa , Alexander Hapfelmeier , Sebastian Kufner , Hendrik B. Sager , Katharina Mayer , Thorsten Kessler , Karl?Ludwig Laugwitz , Gert Richardt , Heribert Schunkert , Franz?Josef Neumann , Adnan Kastrati , and Salvatore Cassese 1 Klinik für Herz? und Kreislauferkrankungen, Deutsches Herzzentrum München Technische Universität München Munich Germany 2 German Center for Cardiovascular Research (DZHK), Partner Site (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThe efficacy and safety of ticagrelor versus prasugrel in patients with acute coronary syndrome and prior myocardial infarction (MI) remain unstudied. We aimed to assess the treatment effect of (...) (Journal of the American Heart Association)
12:26
Peak Work Rate Increases With Lower Extremity?Focused Exercise Training in Adolescents With Fontan Circulation - Catherine M. Avitabile, Michael G. McBride , Xuemei Zhang , Steve Ampah , Bryan H. Goldstein , Tarek Alsaied , Samuel G. Wittekind , Kevin K. Whitehead , Babette S. Zemel , and Stephen M. Paridon 1 Department of Pediatrics University of Pennsylvania Perelman School of Medicine Philadelphia PA 2 Division of Cardiology, Children’s Hospital of Philadelphia Philadelphia PA 3 Department of Pediatrics, Division of Cardiology University of Pittsburgh Medical Center Pittsburgh PA 4 Department of Pediatrics, Division of Cardiology, Cincinnati Children’s Hospital Medical Center Cincinnati OH 5 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundSkeletal muscle deficits are associated with worse exercise performance in the Fontan circulation and may be improved by exercise training. We aimed to assess the change in leg lean mass (a marker of (...) (Journal of the American Heart Association)
12:25
JAHA: The End of the Beginning - Barry London 1 Division of Cardiovascular Medicine and Abboud Cardiovascular Research Center University of Iowa Carver College of Medicine Iowa City IA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. (Journal of the American Heart Association)
12:25
SerpinG1: A Novel Biomarker Associated With Poor Coronary Collateral in Patients With Stable Coronary Disease and Chronic Total Occlusion - Shuai Chen, Le?Ying Li , Zhi?Ming Wu , Yong Liu , Fei?Fei Li , Ke Huang , Yi?Xuan Wang , Qiu?Jing Chen , Xiao?Qun Wang , Wei?Feng Shen , Rui?Yan Zhang , Ying Shen , Lin Lu , Feng?Hua Ding , and Yang Dai 1 Department of Vascular and Cardiology, Rui Jin Hospital Shanghai Jiaotong University School of Medicine Shanghai China 2 Institute of Cardiovascular Diseases Shanghai Jiaotong University School of Medicine Shanghai China 3 Department of Nursing, Chongqing Medical and Pharmaceutical College Chongqing China 4 Shanghai Clinical Research Center for Interventional Medicine Shanghai (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThis study aimed to explore predictive biomarkers of coronary collateralization in patients with chronic total occlusion.Methods and ResultsBy using a microarray expression profiling program downloaded (...) (Journal of the American Heart Association)
12:25
Stroke Outcome Related to Initial Volume Status and Diuretic Use - Christopher J. Renner, Scott E. Kasner , Philip M. Bath , Mona N. Bahouth 1 University of Pennsylvania Philadelphia PA 2 Stroke Trials Unit, University of Nottingham Nottingham United Kingdom 3 Johns Hopkins School of Medicine Baltimore MD, the VISTA Acute Steering Committee [Link] Kennedy R. Lees, Andrei Alexandrov, Philip M. Bath, Erich Bluhmki, Natan Bornstein, Christopher Chen, Stephen M. Davis, Hans?Christoph Diener, Geoffrey Donnan, Marc Fisher, Myron Ginsberg, Barbara Gregson, James Grotta, Werner Hacke, Michael G. Hennerici, Marc Hommel, Markku Kaste, Patrick Lyden, John Marler, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundWe hypothesized that stroke outcome is related to multiple baseline hydration?related factors including volume contracted state (VCS) and diuretic use.Methods and ResultsWe analyzed a prospective cohort (...) (Journal of the American Heart Association)
12:24
Global Characteristics and Dynamics of Single Immune Cells After Myocardial Infarction - Lingfang Zhuang, Yaqiong Wang , Zhaoyang Chen , Zhigang Li , Ziyang Wang , Kangni Jia , Jiaxin Zhao , Hang Zhang , Hongyang Xie , Lin Lu , Kang Chen , Lei Chen , Keiichi Fukuda , Motoaki Sano , Ruiyan Zhang , Jun Liu , and Xiaoxiang Yan 1 Department of Cardiovascular Medicine, Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai PR China 2 Institute of Cardiovascular Diseases Shanghai Jiao Tong University School of Medicine Shanghai PR China 3 Department of Nephrology, Zhongshan Hospital Fudan University Shanghai PR China 4 Shanghai Institute of Immunology Shanghai (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundMyocardial infarction (MI) is characterized by the emergence of dead or dying cardiomyocytes and excessive immune cell infiltration after coronary vessel occlusion. However, the complex transcriptional (...) (Journal of the American Heart Association)
12:24
The Prognostic Value of B?Type Natriuretic Peptide in Patients With Cardiac Sarcoidosis Without Heart Failure: Insights From ILLUMINATE?CS - Shota Miyakuni, Daichi Maeda , Yuya Matsue , Kenji Yoshioka , Taishi Dotare , Tsutomu Sunayama , Takeru Nabeta , Yoshihisa Naruse , Takeshi Kitai , Tatsunori Taniguchi , Hidekazu Tanaka , Takahiro Okumura , Yuichi Baba , Akihiko Matsumura , and Tohru Minamino 1 Department of Cardiovascular Biology and Medicine Juntendo University Graduate School of Medicine Tokyo Japan 2 Department of Cardiology Kameda Medical Center Chiba Japan 3 Department of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Japan 4 Division of Cardiology, Internal Medicine III Hamamatsu (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThe prognostic role of BNP (B?type natriuretic peptide) in patients with cardiac sarcoidosis without evident heart failure is unknown.Methods and ResultsThis is a post hoc analysis of ILLUMINATE?CS (...) (Journal of the American Heart Association)
12:24
In?Hospital Outcomes of Acute Myocardial Infarction With Essential Thrombocythemia and Polycythemia Vera: Insights From the National Inpatient Sample - Jing Wu, YongZhen Fan , Wei Zhao , Bing Li , Naifan Pan , Zhiyang Lou , and Mingyou Zhang 1 Department of Translational Medicine The First Hospital of Jilin University Changchun China 2 Department of Cardiology Zhongnan Hospital Wuhan China 3 Department of Cardiovascular Diseases The First Hospital of Jilin University Changchun China 4 Department of Anesthesiology The First Hospital of Jilin University Changchun China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundAcute myocardial infarction (AMI) with essential thrombocythemia (ET) or polycythemia vera is rare, and there are scarce real?world data on its management and impact on in?hospital outcomes.Methods and (...) (Journal of the American Heart Association)
12:24
Change in Depressive Symptoms During the First Month of Discharge and 1?Year Clinical Outcomes in Patients Hospitalized for Heart Failure - Bin Wang, Lubi Lei , Haibo Zhang , Fengyu Miao , Lihua Zhang , Aoxi Tian , and Jing Li 1 National Clinical Research Center for Cardiovascular Diseases, NHC Key Laboratory of Clinical Research for Cardiovascular Medications, State Key Laboratory of Cardiovascular Disease Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases Beijing People’s Republic of China 2 Fuwai Hospital, Chinese Academy of Medical Sciences Shenzhen People’s Republic of China 3 Central China Subcenter of the National Center for Cardiovascular (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThe patterns of depressive symptom change during the first month after discharge, as well as their prognostic implications, and predictors of persistent or new?onset depressive symptoms are not well (...) (Journal of the American Heart Association)
12:23
Association of Chronic Covert Cerebral Infarctions and White Matter Hyperintensities With Atrial Fibrillation Detection on Post?Stroke Cardiac Rhythm Monitoring: A Cohort Study - Ulfrid Amberger, Julian Lippert , Adnan Mujanovic , Morin Beyeler , Bernhard Siepen , Jan Vynckier , Adrian Scutelnic , Martina Goeldlin , David Seiffge , Simon Jung , Jan Gralla , Marcel Arnold , Johannes Kaesmacher , Tobias Reichlin , Hildegard Tanner , Urs Fischer , Laurent Roten , and Thomas Raphael Meinel 1 Stroke Research Center Bern, Department of Neurology, Inselspital Bern University Hospital, University of Bern Switzerland 2 Institute of Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern Switzerland 3 Department of Cardiology, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThis study was conducted to explore the association of different phenotypes, count, and location of chronic covert brain infarctions (CBIs) with detection of atrial fibrillation (AF) on prolonged (...) (Journal of the American Heart Association)
12:23
Eligibility and Implementation of Rivaroxaban for Secondary Prevention of Atherothrombosis in Clinical Practice—Insights From the CANHEART Study - Maya S. Sheth, Bing Yu , Anna Chu , Joan Porter , Derrick Y Tam , Laura E. Ferreira?Legere , Shaun G. Goodman , Michael E. Farkouh , Dennis T. Ko , Husam Abdel?Qadir , and Jacob A. Udell 1 Women’s College Research Institute Toronto Canada 2 Dalla Lana School of Public Health University of Toronto Canada 3 ICES Toronto Canada 4 Schulich Heart Centre, Sunnybrook Health Sciences Centre Toronto Canada 5 Institute of Health Policy, Management, and Evaluation University of Toronto Canada 6 Applied Health Research Centre, Li Ka Shing Knowledge Institute St Michael’s Hospital Toronto Canada 7 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundThe COMPASS (Cardiovascular Outcomes for People Using Anticoagulation Strategies) trial decreased major adverse cardiovascular events with very low?dose rivaroxaban and aspirin in patients with coronary (...) (Journal of the American Heart Association)
12:23
Impact of Virtual Interviewing on Geographic Placement for Cardiology Fellowship Recruitment - Usman A. Hasnie, Ammar A. Hasnie , Carlos A. Estrada , Gaby Weissman , Winter L. Williams , and Steven G. Lloyd 1 Division of Cardiovascular Disease Heersink School of Medicine at the University of Alabama at Birmingham Birmingham AL 2 Department of Medicine Heersink School of Medicine at the University of Alabama at Birmingham Birmingham AL 3 Section of General Internal Medicine Birmingham Veterans Affairs Medical Center Birmingham AL 4 Department of Cardiology MedStar Heart and Vascular Institute and Georgetown University Washington DC 5 Section of Cardiology Birmingham Veterans Affairs (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundVirtual interviewing for cardiology fellowship was instituted in the 2021 fellowship application cycle because of the COVID?19 pandemic and restricted travel. The impact on geographic patterns of (...) (Journal of the American Heart Association)
12:23
Dihydropyridine Calcium Channel Blockers and Risk of Pancreatic Cancer: A Population?Based Cohort Study - Julie Rouette, Emily G. McDonald , Tibor Schuster , James M. Brophy , and Laurent Azoulay 1 Centre for Clinical Epidemiology Lady Davis Institute, Jewish General Hospital Montreal Canada 2 Department of Epidemiology, Biostatistics, and Occupational Health McGill University Montreal Canada 3 Division of General Internal Medicine, Department of Medicine McGill University Health Centre Montreal Canada 4 Division of Experimental Medicine McGill University Montreal Canada 5 Department of Family Medicine McGill University Montreal Canada 6 Division of Clinical Epidemiology McGill University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundRecent studies have reported that dihydropyridine calcium channel blockers (dCCBs) may increase the risk of pancreatic cancer, but these studies had methodological limitations. We thus aimed to (...) (Journal of the American Heart Association)
12:23
Scaling Peak Oxygen Consumption for Body Size and Composition in People With a Fontan Circulation - Curtis A. Wadey, Alan R. Barker , Graham Stuart , Derek L. Tran , Karina Laohachai , Julian Ayer , Rachael Cordina , and Craig A. Williams 1 Children’s Health & Exercise Research Centre (CHERC) Public Health and Sport Science, Faculty of Health and Life Sciences, University of Exeter Exeter United Kingdom 2 Bristol Congenital Heart Centre, The Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust Bristol United Kingdom 3 Central Clinical School, The University of Sydney Camperdown New South Wales 4 Department of Cardiology Royal Prince Alfred Hospital Camperdown New (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundPeak oxygen consumption (peakV?O2$$ \\dot\\mathrmV\\mathrmO_2 $$) is traditionally divided (“ratio?scaled”) by body mass (BM) for clinical interpretation. Yet, it is unknown whether ratio?scaling to BM can (...) (Journal of the American Heart Association)
12:23
Race, Sex, and Neighborhood Socioeconomic Disparities in Ablation of Ventricular Tachycardia Within a National Medicare Cohort - Ryan Kipp, Matthew Kalscheur , Ann M. Sheehy , Christie M. Bartels , Amy J. H. Kind , and W. Ryan Powell 1 Division of Cardiovascular Medicine, Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI 2 William S. Middleton Memorial Veterans Hospital Madison WI 3 Division of Hospitalist Medicine, Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI 4 Division of Rheumatology, Department of Medicine University of Wisconsin School of Medicine and Public Health Madison WI 5 Center for Health Disparities Research, (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundVentricular tachycardia (VT) ablation significantly improves our ability to control VT, yet little is known about whether disparities exist in delivery of this technology.Methods and ResultsUsing a (...) (Journal of the American Heart Association)
12:22
Utility of the ACC/AHA Lesion Classification to Predict Outcomes After Contemporary DES Treatment: Individual Patient Data Pooled Analysis From 7 Randomized Trials - Maayan Konigstein, Björn Redfors , Zixuan Zhang , Lak N. Kotinkaduwa , Gary S. Mintz , Pieter C. Smits , Patrick W. Serruys , Clemens von Birgelen , Mahesh V. Madhavan , Mordechai Golomb , Ori Ben?Yehuda , Roxana Mehran , Martin B. Leon , and Gregg W. Stone 1 Clinical Trials Center Cardiovascular Research Foundation New York NY 2 Tel?Aviv Medical Center and the Sackler Faculty of Medicine Tel?Aviv University Tel Aviv Israel 3 Sahlgrenska University Hospital Gothenburg Sweden 4 Maasstad Ziekenhuis Rotterdam The Netherlands 5 Imperial College of Science, Technology and Medicine London United (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundUse of the modified American College of Cardiology (ACC)/American Heart Association (AHA) lesion classification as a prognostic tool to predict short? and long?term clinical outcomes after percutaneous (...) (Journal of the American Heart Association)
12:22
A Unique High?Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome - Gautam K. Singh, Conor McClenaghan , Manish Aggarwal , Hongjie Gu , Maria S. Remedi , Dorothy K. Grange , and Colin G. Nichols 1 Division of Cardiology, Department of Pediatrics Washington University School of Medicine St. Louis MO 2 Center for the Investigation of Membrane Excitability Diseases (CIMED) Washington University School of Medicine St. Louis MO 3 Department of Cell Biology and Physiology Washington University School of Medicine St. Louis MO 4 Division of Statistics Washington University School of Medicine St. Louis MO 5 Department of Medicine, Division of Endocrinology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundCardiomegaly caused by left ventricular hypertrophy is a risk factor for development of congestive heart failure, classically associated with decreased systolic and/or diastolic ventricular function. (...) (Journal of the American Heart Association)
12:21
Impact of Socioeconomic Status on Emergency Department Visits in Patients With Atrial Fibrillation: A Nationwide Population?Based Cohort Study - Seo?Young Lee, So?Ryoung Lee , Eue?Keun Choi , Kyung?Do Han , Seil Oh , and Gregory Y. H. Lip 1 Department of Hospital Medicine Center Seoul National University Hospital Seoul Republic of Korea 2 Department of Internal Medicine Seoul National University Hospital Seoul Republic of Korea 3 Department of Statistics and Actuarial Science Soongsil University Seoul Republic of Korea 4 Liverpool Centre for Cardiovascular Science University of Liverpool and Liverpool Heart and Chest Hospital Liverpool UK 5 Department of Clinical Medicine Aalborg University Aalborg (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundSocioeconomic status (SES) differences could influence management and clinical outcomes in patients with atrial fibrillation (AF), reflecting health inequalities. The authors aimed to investigate (...) (Journal of the American Heart Association)
12:19
Left Ventricular Assist Devices: A Primer For the General Cardiologist - Sunit?Preet Chaudhry, Adam D. DeVore , Himabindu Vidula , Michael Nassif , Karol Mudy , Edo Y. Birati , Timothy Gong , Pavan Atluri , Duc Pham , Benjamin Sun , Aditya Bansal , Samer S. Najjar , and 1 Division of Cardiology Ascension St. Vincent Heart Center Indianapolis IN 2 Ascension St. Vincent Cardiovascular Research Institute Indianapolis IN 3 Department of Medicine and Duke Clinical Research Institute Duke University School of Medicine Durham NC 4 Division of Heart Failure and Transplant University of Rochester School of Medicine and Dentistry Rochester NY 5 Division of Heart failure (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. Durable implantable left ventricular assist devices (LVADs) have been shown to improve survival and quality of life for patients with stage D heart failure. Even though LVADs remain underused overall, the number (...) (Journal of the American Heart Association)

1 December

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:03
Association Between Copayment Amount and Filling of Medications for Angiotensin Receptor Neprilysin Inhibitors in Patients With Heart Failure - Amrita Mukhopadhyay, Samrachana Adhikari , Xiyue Li , John A. Dodson , Ian M. Kronish , Binita Shah , Maggie Ramatowski , Rumi Chunara , Sam Kozloff , and Saul Blecker 1 Department of Medicine (Cardiology) New York University School of Medicine New York NY 2 Department of Population Health New York University School of Medicine New York NY 3 Center for Behavioral Cardiovascular Health Columbia University Irving Medical Center New York NY 4 Department of Medicine (Cardiology) VA New York Harbor Healthcare System New York NY 5 Department of Medicine University of Utah Salt Lake City NY 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 24, December 20, 2022. BackgroundAngiotensin receptor neprilysin inhibitors (ARNI) reduce mortality and hospitalization for patients with heart failure. However, relatively high copayments for ARNI may contribute to suboptimal (...) (Journal of the American Heart Association)

16 November

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

02:31
Long?Term Outcomes of Chronic Type B Aortic Dissection Treated by Thoracic Endovascular Aortic Repair - Xiaolang Jiang, Yifan Liu , Lingwei Zou , Bin Chen , Junhao Jiang , Weiguo Fu , and Zhihui Dong 1 Department of Vascular Surgery, Institute of Vascular Surgery Zhongshan Hospital, Fudan University Shanghai China 2 National Clinical Research Center for Interventional Medicine Shanghai China 3 Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital Southern Medical University Guangzhou China 4 Center for Vascular Surgery and Wound Care Jinshan Hospital, Fudan University Shanghai (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 12, Issue 1, January 3, 2023. BackgroundThe treatment of chronic type B aortic dissection by thoracic endovascular aortic repair has some challenges, and its long?term outcomes remain unclear. This study aimed to analyze the 5?year clinical (...) (Journal of the American Heart Association)

27 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:20
Effects of Walking Exercise at a Pace With Versus Without Ischemic Leg Symptoms on Functional Performance Measures in People With Lower Extremity Peripheral Artery Disease: The LITE Randomized Clinical Trial - Michael M. Hammond, Bonnie Spring , W. Jack Rejeski , Robert Sufit , Michael H. Criqui , Lu Tian , Lihui Zhao , Shujun Xu , Melina R. Kibbe , Christiaan Leeuwenburgh , Todd Manini , Daniel E. Forman , Diane Treat?Jacobson , Tamar S. Polonsky , Lydia Bazzano , Luigi Ferrucci , Jack Guralnik , Donald M. Lloyd?Jones , and Mary M. McDermott 1 Northwestern University Feinberg School of Medicine Chicago IL 2 Departments of Health and Exercise Science and Geriatric Medicine Wake Forest University Winston Salem NC 3 University of California at San Diego San Diego CA 4 Department of Biomedical (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundIn people with peripheral artery disease, post hoc analyses of the LITE (Low Intensity Exercise Intervention in Peripheral Artery Disease) randomized trial were conducted to evaluate the effects of walking exercise at a pace (...) (Journal of the American Heart Association)

26 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

06:30
Association of Sleep Duration, Napping, and Sleep Patterns With Risk of Cardiovascular Diseases: A Nationwide Twin Study - Zhiyu Wang, Wenzhe Yang , Xuerui Li , Xiuying Qi , Kuan?Yu Pan , and Weili Xu 1 Department of Epidemiology and Biostatistics, School of Public Health Tianjin Medical University Tianjin China 2 Tianjin Key Laboratory of Environment Nutrition and Public Health Tianjin China 3 Center for International Collaborative Research on Environment Nutrition and Public Health Tianjin China 4 Department of Psychiatry, Amsterdam Public Health Amsterdam University Medical Center, Vrije Universiteit Amsterdam The Netherlands 5 Aging Research Center, Department of Neurobiology, Health Care Sciences and (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundAlthough sleep disorders have been linked to cardiovascular diseases (CVDs), the association between sleep characteristics and CVDs remains inconclusive. We aimed to examine the association of nighttime sleep duration, daytime (...) (Journal of the American Heart Association)

25 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

14:07
RNF213 R4810K Variant in Suspected Unilateral Moyamoya Disease Predicts Contralateral Progression - Taedong Ok, Yo Han Jung , Jinkwon Kim , Sang Kyu Park , Goeun Park , Sujee Lee , and Kyung?Yul Lee 1 Department of Neurology, Gangnam Severance Hospital Yonsei University College of Medicine Seoul South Korea 2 Department of Neurology, Yongin Severance Hospital Yonsei University College of Medicine Yongin South Korea 3 Department of Neurosurgery, Gangnam Severance Hospital Yonsei University College of Medicine Seoul South Korea 4 Biostatistics Collaboration Unit Yonsei University College of Medicine Seoul South (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundEarly?stage unilateral moyamoya disease (MMD) is difficult to discriminate from isolated intracranial atherosclerotic stenosis, and identification of contralateral progression may aid in the diagnosis of MMD. The RNF213 (ring (...) (Journal of the American Heart Association)
14:07
Prognostic Impact of Coronary Flow Reserve in Patients With Reduced Left Ventricular Ejection Fraction - Hyun Sung Joh, Doosup Shin , Joo Myung Lee , Seung Hun Lee , David Hong , Ki Hong Choi , Doyeon Hwang , Coen K. M. Boerhout , Guus A. de Waard , Ji?Hyun Jung , Hernan Mejia?Renteria , Masahiro Hoshino , Mauro Echavarria?Pinto , Martijn Meuwissen , Hitoshi Matsuo , Maribel Madera?Cambero , Ashkan Eftekhari , Mohamed A. Effat , Tadashi Murai , Koen Marques , Joon?Hyung Doh , Evald H. Christiansen , Rupak Banerjee , Hyun Kuk Kim , Chang?Wook Nam , Giampaolo Niccoli , Masafumi Nakayama , Nobuhiro Tanaka , Eun?Seok Shin , Steven A. J. Chamuleau , Niels van Royen , Paul Knaapen , Bon Kwon Koo , (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundIntracoronary physiologic indexes such as coronary flow reserve (CFR) and left ventricular ejection fraction (LVEF) have been regarded as prognostic indicators in patients with coronary artery disease. The current study (...) (Journal of the American Heart Association)
14:06
Conventional Vasopressor and Vasopressor?Sparing Strategies to Counteract the Blood Pressure–Lowering Effect of Small Interfering RNA Targeting Angiotensinogen - Estrellita Uijl, Dien Ye , Liwei Ren , Katrina M. Mirabito Colafella , Richard van Veghel , Ingrid M. Garrelds , Hong S. Lu , Alan Daugherty , Ewout J. Hoorn , Paul Nioi , Don Foster , and A. H. Jan Danser 1 Division of Vascular Medicine and Pharmacology, Department of Internal Medicine Erasmus MC, University Medical Center Rotterdam Rotterdam the Netherlands 2 Division of Nephrology and Transplantation, Department of Internal Medicine Erasmus MC, University Medical Center Rotterdam Rotterdam the Netherlands 3 Saha Cardiovascular Research Center and Department of Physiology University of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundA single dose of small interfering RNA (siRNA) targeting liver angiotensinogen eliminates hepatic angiotensinogen and lowers blood pressure. Angiotensinogen elimination raises concerns for clinical application because an (...) (Journal of the American Heart Association)
14:06
Value of Periprocedural Electrophysiology Testing During Transcatheter Aortic Valve Replacement for Risk Stratification of Patients With New?Onset Left Bundle?Branch Block - Patrick Badertscher, Sven Knecht , Florian Spies , Chloé Auberson , Marc Salis , Raban V. Jeger , Gregor Fahrni , Christoph Kaiser , Beat Schaer , Stefan Osswald , Christian Sticherling , and Michael Kühne 1 Department of Cardiology University Hospital Basel Basel Switzerland 2 Cardiovascular Research Institute Basel, University Hospital Basel Basel Switzerland J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundDespite being the most frequent complication following transcatheter aortic valve replacement (TAVR), optimal management of left bundle?branch block (LBBB) remains unknown. Electrophysiology study has been proposed for risk (...) (Journal of the American Heart Association)
14:06
Educational Needs of People Living with Atrial Fibrillation: A Qualitative Study - Caleb Ferguson, Louise D. Hickman , Lien Lombardo , Annie Downie , Beata Bajorek , Serra Ivynian , Sally C. Inglis , and Rochelle Wynne 1 Western Sydney Nursing & Midwifery Research Centre Western Sydney Local Health District and Western Sydney University, Blacktown Hospital Blacktown New South Wales Australia 2 School of Nursing University of Wollongong Wollongong New South Wales Australia 3 Department of Cardiology The Sutherland Hospital Caringbah Australia 4 Faculty of Health University of Technology Sydney Sydney New South Wales Australia 5 School of Nursing & Midwifery Deakin (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThis study explored the educational and self?management needs of adults living with atrial fibrillation (AF).Methods and ResultsThis is a qualitative study of adults living with AF, clinicians, and expert key stakeholders. (...) (Journal of the American Heart Association)
14:06
Incidence and Risk Factors for Residual Adverse Events Despite Anticoagulation in Atrial Fibrillation: Results From Phase II/III of the GLORIA?AF Registry - Wern Yew Ding, Deirdre A. Lane , Dhiraj Gupta , Menno V. Huisman , Gregory Y. H. Lip , and 1 Liverpool Centre for Cardiovascular Science University of Liverpool and Liverpool Heart & Chest Hospital Liverpool UK 2 Department of Clinical Medicine Aalborg University Aalborg Denmark 3 Department of Thrombosis and Hemostasis Leiden University Medical Center Leiden the Netherlands J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundResidual risk of ischemic stroke despite anticoagulation in patients with atrial fibrillation (AF) represents a significant clinical issue that remains unaddressed. We aimed to evaluate the incidence and risk factors for (...) (Journal of the American Heart Association)
14:05
Fibroblast Growth Factor 23 and Risk of New Onset Heart Failure With Preserved or Reduced Ejection Fraction: The PREVEND Study - S. Heleen Binnenmars, Georgette E. Hoogslag , Stanley M. H. Yeung , Frank P. Brouwers , Stephan J. L. Bakker , Wiek H. van Gilst , Ron T. Gansevoort , Gerjan Navis , Adriaan A. Voors , and Martin H. de Borst 1 Department of Internal Medicine, Division of Nephrology University of Groningen, University Medical Center Groningen Groningen The Netherlands 2 Department of Cardiology University of Groningen, University Medical Center Groningen Groningen The (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe role of fibroblast growth factor 23 (FGF23) in the development of new?onset heart failure (HF) with reduced (HFrEF) or preserved ejection fraction (HFpEF) in the general population is unknown. Therefore, we set out to (...) (Journal of the American Heart Association)
14:05
Mortality and Cardiovascular Outcomes in Patients Presenting With Non–ST Elevation Myocardial Infarction Despite No Standard Modifiable Risk Factors: Results From the SWEDEHEART Registry - Gemma A. Figtree, Stephen T. Vernon , Nermin Hadziosmanovic , Johan Sundström , Joakim Alfredsson , Stephen J. Nicholls , Clara K. Chow , Peter Psaltis , Helge Røsjø , Margrét Leósdóttir , and Emil Hagström 1 Kolling Institute, Royal North Shore Hospital and University of Sydney Sydney Australia 2 Department of Cardiology Royal North Shore Hospital Sydney Australia 3 Department of Medical Sciences Uppsala University Uppsala Sweden 4 The George Institute for Global Health UNSW Sydney Sydney Australia 5 Faculty of Medicine and Health Sciences Linköping University Linköping Sweden 6 Monash (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundA significant proportion of patients with ST?segment–elevation myocardial infarction (MI) have no standard modifiable cardiovascular risk factors (SMuRFs) and have unexpected worse 30?day outcomes compared with those with SMuRFs. (...) (Journal of the American Heart Association)
14:05
Identifying Differences: A Key Step in Precision Cardiovascular Disease Prevention - Mahmoud Al Rifai, Salim S. Virani , and Vijay Nambi 1 Section of Cardiology Department of Medicine Baylor College of Medicine Houston TX 2 Section of Cardiology, Michael E. DeBakey Veterans Affairs Medical Center Houston TX 3 Division of Cardiovascular Research Baylor College of Medicine Houston TX J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
14:04
Mid? to Late?Life Time?Averaged Cumulative Blood Pressure and Late?Life Retinal Microvasculature: The ARIC Study - Yiquan Huang, Huimin Zhou , Shaozhao Zhang , Xiangbin Zhong , Yifen Lin , Zhenyu Xiong , Menghui Liu , Aili· Yimamu , Odong Christopher , Ziwei Zhou , Xiaodong Zhuang , and Xinxue Liao 1 Cardiology Department First Affiliated Hospital of Sun Yat?Sen University Guangzhou China 2 National Health Commission (NHC) Key Laboratory of Assisted Circulation (Sun Yat?Sen University) Guangzhou China J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe associations of time?averaged cumulative blood pressure (BP) from midlife to late life with microvasculature expressed as retinal vessel diameters is not well studied. The aim of this study was to evaluate the association (...) (Journal of the American Heart Association)
14:04
Cardiovascular Safety Reporting in Contemporary Breast Cancer Clinical Trials - Arsalan Hamid, Markus S. Anker , John C. Ruckdeschel , Muhammad Shahzeb Khan , Arsal Tharwani , Adebamike A. Oshunbade , Rodney K. Kipchumba , Samuel C. Thigpen , Stefan D. Anker , Gregg C. Fonarow , Michael E. Hall , and Javed Butler 1 Department of Medicine University of Mississippi Medical Center Jackson MS 2 Department of Cardiology (CBF), Charité University Medicine Berlin Berlin Germany 3 Berlin Institute of Health Center for Regenerative Therapies (BCRT) Berlin Germany 4 DZHK (German Centre for Cardiovascular Research), partner site Berlin Berlin Germany 5 Division of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundSeveral cancer therapies have been associated with cardiovascular harm in early?phase clinical trials. However, some cardiovascular harms do not manifest until later?phase trials. To limit interdisease variability, we focused on (...) (Journal of the American Heart Association)
14:03
Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima?Media Thickness: An Individual Participant Data Meta?Analysis - Engelbert A. Nonterah, Nigel J. Crowther , Kerstin Klipstein?Grobusch , Abraham R. Oduro , Maryam Kavousi , Godfred Agongo , Todd J. Anderson , Gershim Asiki , Palwendé R. Boua , Solomon S. R. Choma , David J. Couper , Gunnar Engström , Jacqueline de Graaf , Jussi Kauhanen , Eva M. Lonn , Ellisiv B. Mathiesen , Lisa K. Micklesfield , Shuhei Okazaki , Joseph F. Polak , Tatjana Rundek , Jukka T. Salonen , Stephen M. Tollman , Tomi?Pekka Tuomainen , Diederick E. Grobbee , Michéle Ramsay , Michiel L. Bots , and 1 Navrongo Health Research Centre Ghana Health Service Navrongo Ghana 2 Julius Global (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe major risk factors for atherosclerotic cardiovascular disease differ by race or ethnicity but have largely been defined using populations of European ancestry. Despite the rising prevalence of cardiovascular disease in (...) (Journal of the American Heart Association)
14:03
Trends in Uptake and Adherence to Oral Anticoagulation for Patients With Incident Atrial Fibrillation at High Stroke Risk Across Health Care Settings - Haran Yogasundaram, Douglas C. Dover , Nathaniel M. Hawkins , Finlay A. McAlister , Shaun G. Goodman , Justin Ezekowitz , Padma Kaul , and Roopinder K. Sandhu 1 Division of Cardiology University of Alberta Edmonton Alberta Canada 2 Canadian VIGOUR Center University of Alberta Edmonton Alberta Canada 3 Division of General Internal Medicine University of Alberta Edmonton Alberta Canada 4 Division of Cardiology University of British Columbia Vancouver British Columbia Canada 5 St. Michael’s Hospital University of Toronto Ontario Canada 6 Smidt Heart Institute, Cedars?Sinai Medical Center Los (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundOral anticoagulation (OAC) therapy prevents morbidity and mortality in nonvalvular atrial fibrillation; whether location of diagnosis influences OAC uptake or adherence is unknown.Methods and ResultsRetrospective cohort study (...) (Journal of the American Heart Association)
14:02
Platypnea?Orthodeoxia Syndrome in the Setting of Patent Foramen Ovale Without Pulmonary Hypertension or Major Lung Disease - Farrah Othman, Brian Bailey , Nicholas Collins , Edmund Lau , David Tanous , Karan Rao , David Celermajer , and Rachael Cordina 1Royal Prince Alfred Hospital Sydney NSW Australia 2John Hunter Hospital Newcastle NSW Australia 3Westmead Hospital Sydney NSW Australia 4Heart Research Institute Sydney NSW Australia 5Sydney Medical SchoolUniversity of Sydney NSW Australia J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundPatent foramen ovale (PFO)?associated platypnea?orthodeoxia syndrome is characterized by dyspnea and hypoxemia when upright. The pathogenesis is thought to involve an increase in right atrial pressure or change in degree of (...) (Journal of the American Heart Association)

20 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:22
Neurological Deterioration in Intracerebral Hemorrhage: Can We Predict It, and What Would We Do If We Could? - Qi Li, and Joshua N. Goldstein 1 Department of Neurology The Second Affiliated Hospital of Anhui Medical University Hefei China 2 Department of Neurology The First Affiliated Hospital of Chongqing Medical University Chongqing China 3 Division of Neurocritical Care and Emergency Neurology, Department of Emergency Medicine Massachusetts General Hospital, Harvard Medical School Boston MA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
12:20
Prediction of Neurological Deterioration After Intracerebral Hemorrhage: The SIGNALS Score - Quanwei He, Hongxiu Guo , Rentang Bi , Shaoli Chen , Jing Shen , Chunnan Long , Man Li , Yuanpeng Xia , Lei Zhang , Zhou Sun , Xiaolu Chen , Zhaowei Wang , Daokai Gong , Jingwen Xu , Dondya Zhu , Yan Wan , and Bo Hu 1 Department of Neurology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province China 2 Department of Neurology Qianjiang Central Hospital Qianjiang Hubei Province China 3 Department of Neurology Jingzhou Central Hospital Jingzhou Hubei Province China 4 Department of Neurology Honghu People’s Hospital Honghu Hubei Province (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundIntracerebral hemorrhage is the most disabling and lethal form of stroke. We aimed to develop a novel clinical score for neurological deterioration during hospitalization after intracerebral hemorrhage.Methods and ResultsWe (...) (Journal of the American Heart Association)
11:37
Patients With Congenital Heart Disease Undergoing Noncardiac Procedures at Hospitals With and Without a Cardiac Surgical Program - Viviane G. Nasr, Urbano L. França , Meena Nathan , James A. DiNardo , David Faraoni , and Michael L. McManus 1 Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital, Harvard Medical School Boston MA 2 Department of Cardiac Surgery Boston Children's Hospital, Harvard Medical School Boston MA 3 Department of Anesthesiology, Perioperative and Pain Medicine Texas Children's Hospital, Baylor College of Medicine Houston (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe type and location of hospitals where patients with congenital heart disease (CHD) undergo noncardiac procedures have not been investigated. This study aimed to describe (1) the characteristics of these patients, (2) the (...) (Journal of the American Heart Association)
11:37
Long?Term Outcomes of Pulmonary Vein Isolation in Patients With Brugada Syndrome and Paroxysmal Atrial Fibrillation - Antonio Bisignani, Giulio Conte , Luigi Pannone , Juan Sieira , Alvise Del Monte , Felicia Lipartiti , Gezim Bala , Vincenzo Miraglia , Cinzia Monaco , Erwin Ströker , Ingrid Overeinder , Alexandre Almorad , Anaïs Gauthey , Livia Franchetti Pardo , Matthias Raes , Olivier Detriche , Pedro Brugada , Angelo Auricchio , Gian?Battista Chierchia , and Carlo de Asmundis 1 Postgraduate Program in Cardiac Electrophysiology and Pacing, Heart Rhythm Management Centre, European Reference Networks Guard?Heart Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel Brussels Belgium 2 Anaesthesiology (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundPharmacological treatment of atrial fibrillation (AF) in the setting of Brugada syndrome (BrS) is challenging. In addition, patients with BrS with an implantable cardioverter?defibrillator (ICD) might experience inappropriate (...) (Journal of the American Heart Association)
11:37
Incidence of Preclinical Heart Failure in a Community Population - Kathleen A. Young, Christopher G. Scott , Richard J. Rodeheffer , and Horng H. Chen 1 Department of Cardiovascular Diseases Mayo Clinic Rochester MN United States 2 Division of Biomedical Statistics and Informatics Mayo Clinic Rochester MN United States J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundA high prevalence of preclinical heart failure (HF) (Stages A and B) has previously been shown. The aim of this study was to explore factors associated with the incidence of preclinical HF in a community population.Methods and (...) (Journal of the American Heart Association)
11:36
Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke - Emy A. Thomas, Nitesh Enduru , Adrienne Tin , Eric Boerwinkle , Michael E. Griswold , Thomas H. Mosley , Rebecca F. Gottesman , and Myriam Fornage 1 Brown Foundation Institute of Molecular Medicine McGovern Medical School, University of Texas Health Science Center at Houston Houston TX 2 Department of Medicine University of Mississippi Jackson MS 3 Human Genetics Center, School of Public Health University of Texas Health Science Center at Houston Houston TX 4 Department of Biostatistics University of Mississippi Jackson MS 5 The MIND Center University of Mississippi Medical Center Jackson (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundRecent genetic discoveries in stroke have unleashed the potential of using genetic information for risk prediction and health interventions aimed at disease prevention. We sought to estimate the lifetime risk of stroke (LTRS) (...) (Journal of the American Heart Association)

19 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:02
How Well Do ICD?9?CM Codes Predict True Congenital Heart Defects? A Centers for Disease Control and Prevention?Based Multisite Validation Project - Fred H. Rodriguez, Cheryl L. Raskind?Hood , Trenton Hoffman , Sherry L. Farr , Jill Glidewell , Jennifer S. Li , Alfred D'Ottavio , Lorenzo Botto , Matthew R. Reeder , Daphne Hsu , George K. Lui , Anaclare M. Sullivan , and Wendy M. Book 1 Division of Cardiology Emory University School of Medicine and Emory University Rollins School of Public Health Atlanta GA 2 Sibley Heart Center Cardiology Atlanta GA 3 National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention Atlanta GA 4 Duke University School of Medicine Durham NC 5 Division of (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe Centers for Disease Control and Prevention's Surveillance of Congenital Heart Defects Across the Lifespan project uses large clinical and administrative databases at sites throughout the United States to understand (...) (Journal of the American Heart Association)
11:02
Rural Residence and Antihypertensive Medication Use in US Stroke Survivors - Phoebe M. Tran, Lam T. Tran , Cenjing Zhu , Tiffany Chang , Inna P. Powers , Larry B. Goldstein , and Judith H. Lichtman 1 Department of Public Health University of Tennessee Knoxville TN 2 Department of Biostatistics University of Michigan Ann Arbor MI 3 Department of Chronic Disease Epidemiology Yale University New Haven CT 4 University of Colorado School of Medicine Aurora CO 5 Department of Neurology University of Kentucky Lexington KY J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundRelatively greater increases in hypertension prevalence among US rural residents may contribute to geographic disparities in recurrent stroke. There is limited US information on poststroke antihypertensive medication use by (...) (Journal of the American Heart Association)
11:02
Association of High?Sensitivity Troponin T and I Blood Concentrations With All?Cause Mortality and Cardiovascular Outcome in Stable Patients—Results From the INTERCATH Cohort - Benjamin Bay, Alina Goßling , Christopher M. Blaum , Friederike Kroeger , Luise Koppe , Thiess Lorenz , Lukas Koester , Peter Clemmensen , Dirk Westermann , Paulus Kirchhof , Stefan Blankenberg , Tanja Zeller , Moritz Seiffert , Christoph Waldeyer , and Fabian J. Brunner 1 Department of Cardiology University Heart & Vascular Center Hamburg, University Medical Center Hamburg?Eppendorf Hamburg Germany 2 German Center for Cardiovascular Research, Partner Site Hamburg/Kiel/Lübeck Hamburg Germany 3 Department of Regional Health Research, Faculty of Health Sciences University of Southern Denmark (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundThe association between high?sensitivity troponin T (hsTnT) and high?sensitivity troponin I (hsTnI) and outcome when adjusted for confounders including the angiographical severity of coronary artery disease (CAD) remains largely (...) (Journal of the American Heart Association)
11:01
Proportionate and Absolute Vascular Disease Mortality by Race and Sex in the United States From 1999 to 2019 - Scott E. Janus, Tarek Chami , Haytham Mously , Jamal Hajjari , Tarek Hammad , Yulanka Castro?Dominguez , Foluso Fakorede , Khendi White Solaru , Mehdi H. Shishehbor , Sadeer G. Al?Kindi , and Jun Li 1 Department of Medicine University Hospitals Cleveland OH 2 Harrington Heart and Vascular Institute University Hospitals and School of Medicine, Case Western Reserve University Cleveland OH 3 Minneapolis Heart Institute Minneapolis MN 4 Cardiovascular Solutions of Central Mississippi Cleveland (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundDespite the known significant morbidity and mortality associated with cardiovascular disease and peripheral vascular disease (PVD), contemporary data describing racial demographics in PVD mortality are scarce.Methods and (...) (Journal of the American Heart Association)
11:01
Angiotensin II Receptor Blockers and Arrhythmias in Ventricular Hypertrophy - Guy Salama 1 Department of Medicine University of Pittsburgh, School of Medicine Pittsburgh PA J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
11:01
Candesartan Cilexetil Attenuates Arrhythmogenicity Following Pressure Overload in Rats via the Modulation of Cardiac Electrical and Structural Remodeling and Calcium Handling Dysfunction - Gwo?Jyh Chang, Yung?Hsin Yeh , Wei?Jan Chen , Yu?Shien Ko , Ying?Ju Lai , and Yun?Shien Lee 1 Graduate Institute of Clinical Medicinal Sciences College of Medicine Chang Gung University Tao?Yuan Taiwan 2 Cardiovascular Division of Medicine Chang Gung Memorial Hospital Tao?Yuan Taiwan 3 Department of Respiratory Therapy College of Medicine Chang Gung University Tao?Yuan Taiwan 4 Genomic Medicine Research Core Laboratory Chang Gung Memorial Hospital Tao?Yuan Taiwan 5 Department of Biotechnology Ming Chuan University Tao?Yuan (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundCardiac hypertrophy is associated with abnormal electrophysiology and increased arrhythmia risk. This study assessed whether candesartan cilexetil, an angiotensin II type 1 receptor blocker, could suppress arrhythmogenecity by (...) (Journal of the American Heart Association)
11:00
Editors and Editorial Board J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. (Journal of the American Heart Association)

15 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:43
Serum Neurofilament Light Chain in Patients With Atrial Fibrillation - Karl Sjölin, Julia Aulin , Lars Wallentin , Niclas Eriksson , Claes Held , Kim Kultima , Jonas Oldgren , and Joachim Burman 1 Department of Medical Sciences, Neurology Uppsala University Uppsala Sweden 2 Department of Medical Sciences, Cardiology Uppsala University Uppsala Sweden 3 Uppsala Clinical Research Center (UCR) Uppsala University Uppsala Sweden 4 Department of Medical Sciences, Clinical Chemistry Uppsala University Uppsala Sweden J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundAtrial fibrillation (AF) is associated with stroke and MRI features of cerebral tissue damage but its impact on levels of serum neurofilament light chain (sNFL), an established biochemical marker of (...) (Journal of the American Heart Association)
12:42
RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease - Chisato Shimizu, Jihoon Kim , Ming He , Adriana H. Tremoulet , Hal M. Hoffman , John Y?J. Shyy , and Jane C. Burns 1 Department of Pediatrics University of California, San Diego La Jolla CA 2 Department of Biomedical Informatics University of California, San Diego La Jolla CA 3 Department of Medicine University of California, San Diego La Jolla CA 4 Rady Children’s Hospital San Diego CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundDamage to the coronary arteries during the acute phase of Kawasaki disease (KD) is linked to inflammatory cell infiltration, myointimal proliferation, and endothelial cell (EC) dysfunction. To understand (...) (Journal of the American Heart Association)
12:42
Hypertension Treatment and Control in a New York City Health Care System - Ayana K. April?Sanders, Ladan Golestaneh , Lili Zhang , Katrina Swett , Paul Meissner , and Carlos J. Rodriguez 1 Department of Medicine, Cardiology Albert Einstein College of Medicine/Montefiore Medical Center Bronx NY 2 Renal Division, Department of Medicine Albert Einstein College of Medicine/Montefiore Medical Center Bronx NY 3 Department of Family and Social Medicine Albert Einstein College of Medicine/Montefiore Medical Center Bronx NY J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. (Journal of the American Heart Association)
12:42
Association of Smartphone?Recorded Steps Over Years and Change in Cardiovascular Risk Factors Among Working?Age Adults - Rikuta Hamaya, Masaki Mori , Kuniaki Miyake , and I?Min Lee 1 Division of Preventive Medicine, Department of Medicine Brigham and Women’s Hospital and Harvard Medical School Boston MA 2 Department of Epidemiology Harvard T.H. Chan School of Public Health Boston MA 3 DeSC Healthcare Inc. Tokyo Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundFew data exist on long?term steps and their relation to changes in cardiovascular disease risk factors. We aimed to examine the associations using long?term smartphone?recorded steps.Methods and ResultsThe (...) (Journal of the American Heart Association)
12:41
Atrial Fibrillation and the Risk of Early?Onset Dementia: A Systematic Review and Meta?Analysis - Maria Edvige Giannone, Tommaso Filippini , Paul K. Whelton , Annalisa Chiari , Marco Vitolo , Giuseppe Boriani , and Marco Vinceti 1 Department of Biomedical, Metabolic and Neural Sciences, Environmental, Genetic and Nutritional Epidemiology Research Center University of Modena and Reggio Emilia Modena Italy 2 School of Public Health University of California Berkeley Berkeley CA 3 Department of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA 4 Neurology Unit, Department of Neurosciences Azienda Ospedaliero Universitaria di Modena Modena Italy 5 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundRecent studies have identified an increased risk of dementia in patients with atrial fibrillation (AF). However, both AF and dementia usually manifest late in life. Few studies have investigated this (...) (Journal of the American Heart Association)
12:41
High Fluid Shear Stress Inhibits Cytokine?Driven Smad2/3 Activation in Vascular Endothelial Cells - Hanqiang Deng, and Martin A. Schwartz 1 Department of Internal Medicine, Yale Cardiovascular Research Center Yale University School of Medicine New Haven CT 2 Department of Cell Biology Yale University School of Medicine New Haven CT 3 Department of Biomedical Engineering Yale University New Haven CT J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundAtherosclerosis occurs preferentially in regions of low and disturbed fluid shear stress (FSS) but is limited in regions of high laminar FSS as a result of inhibition of endothelial inflammatory pathways. (...) (Journal of the American Heart Association)
12:41
Procedural Characteristics of Intravascular Ultrasound–Guided Percutaneous Coronary Intervention and Their Clinical Implications - Seung?Yul Lee, Jun?Jie Zhang , Gary S. Mintz , Sung?Jin Hong , Chul?Min Ahn , Jung?Sun Kim , Byeong?Keuk Kim , Young?Guk Ko , Donghoon Choi , Yangsoo Jang , Jing Kan , Tao Pan , Xiaofei Gao , Zhen Ge , Shao?Liang Chen , and Myeong?Ki Hong 1Regional Cardiocerebrovascular CenterWonkwang University Hospital Iksan Korea 2Nanjing First HospitalNanjing Medical University Nanjing China 3Cardiovascular Research Foundation New York NY 4Severance Cardiovascular HospitalYonsei University College of Medicine Seoul Korea 5CHA University College of Medicine Seongnam (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundDespite the clinical benefits to intravascular ultrasound (IVUS) guidance for percutaneous coronary intervention (PCI), most patients with coronary artery disease undergo angiography?guided PCI alone in the (...) (Journal of the American Heart Association)
12:40
Interatrial Block Predicts Life?Threatening Arrhythmias in Dilated Cardiomyopathy - Michiel T. H. M. Henkens, Helena López Martínez , Jerremy Weerts , Arjan Sammani , Anne G. Raafs , Job A. J. Verdonschot , Rutger R. van de Leur , Maurits A. Sikking , Sophia Stroeks , Vanessa P. M. van Empel , Hans?Peter Brunner?La Rocca , Antonius M. W. van Stipdonk , Dimitrios Farmakis , Mark R. Hazebroek , Kevin Vernooy , Antoni Bayés?de?Luna , Folkert W. Asselbergs , Antoni Bayés?Genís , and Stephane R. B. Heymans 1Department of Cardiology, CARIM Maastricht University Medical Centre Maastricht The Netherlands 2Netherlands Heart Institute Utrecht The Netherlands 3Hospital Universitari (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundInteratrial block (IAB) has been associated with supraventricular arrhythmias and stroke, and even with sudden cardiac death in the general population. Whether IAB is associated with life?threatening (...) (Journal of the American Heart Association)
12:40
Incidence and Risk Factors of Pulmonary Hypertension After Venous Thromboembolism: An Analysis of a Large Health Care Database - Pamela L. Lutsey, Line H. Evensen , Thenappan Thenappan , Kurt W. Prins , Rob F. Walker , Joel F. Farley , Richard F. MacLehose , Alvaro Alonso , and Neil A. Zakai 1Division of Epidemiology & Community Health School of Public Health University of Minnesota Minneapolis MN 2K.G. Jebsen ? Thrombosis Research and Expertise Center (TREC) Department of Clinical Medicine UiT The Arctic University of Norway Tromsø Norway 3Division of Cardiovascular Sciences School of Medicine University of Minnesota Minneapolis MN 4Department of Pharmaceutical Care and Health Systems College of Pharmacy University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundPulmonary hypertension (PH) is a devastating potential complication of pulmonary embolism, a manifestation of venous thromboembolism (VTE). The incidence of and risk factors for PH in those with prior VTE (...) (Journal of the American Heart Association)

14 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:59
Association Between Community?Level Violent Crime and Cardiovascular Mortality in Chicago: A Longitudinal Analysis - Lauren A. Eberly, Howard Julien , Eugenia C. South , Atheendar Venkataraman , Ashwin S. Nathan , Emeka C. Anyawu , Elias Dayoub , Peter W. Groeneveld , and Sameed Ahmed M. Khatana 1 Cardiovascular Division Perelman School of Medicine at the University of Pennsylvania Philadelphia PA 2 Center for Cardiovascular Outcomes, Quality, and Evaluative Research University of Pennsylvania Philadelphia PA 3 Penn Cardiovascular Center for Health Equity and Social Justice University of Pennsylvania Philadelphia PA 4 Leonard Davis Institute of Health Economics at the University of Pennsylvania (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundViolent crime has recently increased in many major metropolitan cities in the United States. Prior studies suggest an association between neighborhood crime levels and cardiovascular disease, but many have (...) (Journal of the American Heart Association)

13 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:09
Risk Prediction and Right Ventricular Dilation in a Single?Institution Pulmonary Arterial Hypertension Cohort - Hongyang Pi, Selma D. Carlson , Lia M. Barros , Laurie Hogl , James N. Kirkpatrick , Stephanie Nolley , David D. Ralph , Samuel G. Rayner , and Peter J. Leary 1 Department of Medicine University of Washington Seattle WA 2 Department of Medicine Veterans Administration Minneapolis Minneapolis MN 3 Department of Epidemiology University of Washington Seattle WA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. (Journal of the American Heart Association)
12:09
Characteristics Associated With Growth Differentiation Factor 15 in Heart Failure With Preserved Ejection Fraction and the Impact of Pirfenidone - Gavin A. Lewis, Anna Rosala?Hallas , Susanna Dodd , Erik B. Schelbert , Simon G. Williams , Colin Cunnington , Theresa McDonagh , and Christopher A. Miller 1 Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre University of Manchester Manchester United Kingdom 2 Manchester University NHS Foundation Trust Manchester United Kingdom 3 Liverpool Clinical Trials Centre, Clinical Directorate, Faculty of Health and Life Sciences, University of Liverpool (a member of Liverpool Health Partners) Alder (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundGrowth differentiation factor 15 (GDF?15) is elevated in heart failure with preserved ejection fraction and is associated with adverse outcome, but its relationship with myocardial fibrosis and other (...) (Journal of the American Heart Association)
12:09
Renin?Angiotensin and Endothelin Systems in Patients Post?Takotsubo Cardiomyopathy - Hilal Khan, Amelia Rudd , David T. Gamble , Alice M. Mezincescu , Lesley Cheyne , Graham Horgan , Neeraj Dhaun , David E. Newby , and Dana K Dawson 1 University of Aberdeen United Kingdom 2 University of Edinburgh United Kingdom J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundWe investigate if renin?angiotensin and endothelin?1 response pathways follow the same pattern of recovery as left ventricular ejection fraction in patients with takotsubo cardiomyopathy.Methods and (...) (Journal of the American Heart Association)
11:59
Left Ventricular Strain Analysis During Submaximal Semisupine Bicycle Exercise Stress Echocardiography in Childhood Cancer Survivors - Fabian von Scheidt, Christine Pleyer , Verena Kiesler , Peter Bride , Stephan Bartholomae , Johannes Krämer , Michael Kaestner , and Christian Apitz 1 Division of Pediatric Cardiology, Children’s Hospital University of Ulm Germany 2 Division of Pediatric Oncology, Children’s Hospital University of Ulm Germany J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundChildhood cancer survivors (CCSs) show relevant cardiac morbidity and mortality throughout life. Early detection is key for optimal support of patients at risk. The aim of this study was to evaluate (...) (Journal of the American Heart Association)
11:58
Candidate Plasma Biomarkers to Detect Anthracycline?Related Cardiomyopathy in Childhood Cancer Survivors: A Case Control Study in the Dutch Childhood Cancer Survivor Study - Jan M. Leerink, Elizabeth A. M. Feijen , Perry D. Moerland , Esmee C. de Baat , Remy Merkx , Helena J. H. van der Pal , Wim J. E. Tissing , Marloes Louwerens , Marry M. van den Heuvel?Eibrink , A. Birgitta Versluys , Folkert W. Asselbergs , Arjan Sammani , Arco J. Teske , Elvira C. van Dalen , Margriet van der Heiden?van der Loo , Eline van Dulmen?den Broeder , Andrica C. H. de Vries , Livia Kapusta , Jacqueline Loonen , Yigal M. Pinto , Leontien C. M. Kremer , Annelies M. C. Mavinkurve?Groothuis , and Wouter E. M. Kok 1 Department of Cardiology, Amsterdam Cardiovascular Sciences (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundPlasma biomarkers may aid in the detection of anthracycline?related cardiomyopathy (ACMP). However, the currently available biomarkers have limited diagnostic value in long?term childhood cancer survivors. (...) (Journal of the American Heart Association)
11:58
Preclinical Aortic Atherosclerosis in Adolescents With Chronic Disease - Francesca A. Ververs, Anouk L. M. Eikendal , Daniel Kofink , Roos Nuboer , Jos J. M. Westenberg , Gijs T. Hovenkamp , Jitske J.A. Kemps , Iris C. J. Coenen , Joëlle J. N. Daems , Laura R. Claus , Yillie Ju , Nico M. Wulffraat , Cornelis K. van der Ent , Claudia Monaco , Marianne Boes , Tim Leiner , Heynric B. Grotenhuis , and Henk S. Schipper 1Center for Translational Immunology University Medical Center Utrecht Utrecht the Netherlands 2Department of Radiology University Medical Center Utrecht Utrecht the Netherlands 3Department of Cardiology University Medical Center Utrecht Utrecht the (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundAdolescents with chronic disease are often exposed to inflammatory, metabolic, and hemodynamic risk factors for early atherosclerosis. Since postmortem studies have shown that atherogenesis starts in the (...) (Journal of the American Heart Association)
11:56
Racial and Ethnic Disparities in Incidence and Prognosis of Perioperative Stroke Among Pediatric Cardiac Transplant Recipients - Laura L. Lehman, Elizabeth Mostofsky , Soziema Salia , Suruchi Gupta , Francisco J. Barrera , Lathan Liou , and Murray A. Mittleman 1 Department of Neurology Boston Children’s Hospital Boston MA 2 Harvard Medical School Boston MA 3 Department of Epidemiology Harvard T.H. Chan School of Public Health Boston MA 4 Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine Beth Israel Deaconess Medical Center Boston MA 5 Harvard Vanguard Medical Associates Boston Boston MA 6 Merck & Co., Merck Research Laboratories Boston MA 7 Division of Cardiovascular Medicine, Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundIn the general population, Black children have a higher incidence of stroke and all?cause mortality after stroke than White children. Beginning 6 months following cardiac transplantation, Black children have (...) (Journal of the American Heart Association)

8 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:26
Utility of Provocative Testing in the Diagnosis and Genotyping of Congenital Long QT Syndrome: A Systematic Review and Meta?Analysis - Ying Yang, Ting?ting Lv , Si?yuan Li , Peng Liu , Qing?gele Gao , and Ping Zhang 1School of Clinical Medicine Tsinghua University Beijing China 2Department of Cardiology School of Clinical Medicine Beijing Tsinghua Changgung HospitalTsinghua University Beijing China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundDiagnosis is particularly challenging in concealed or asymptomatic long QT syndrome (LQTS). Provocative testing, unmasking the characterization of LQTS, is a promising alternative method for the diagnosis (...) (Journal of the American Heart Association)
13:25
Qualitative Study of Long?Term Cardiac Arrest Survivors’ Challenges and Recommendations for Improving Survivorship - Alex Presciutti, Bonnie Siry?Bove , Mary M. Newman , Jonathan Elmer , Jim Grigsby , Kevin S. Masters , Jonathan A. Shaffer , Ana?Maria Vranceanu , and Sarah M. Perman 1 Department of Psychology University of Colorado Denver Denver CO 2 Department of Psychiatry Center for Health Outcomes and Interdisciplinary Research, Massachusetts General Hospital Boston MA 3 Department of Psychiatry Harvard Medical School Boston MA 4 Department of Emergency Medicine University of Colorado School of Medicine Denver CO 5 Sudden Cardiac Arrest Foundation Wexford PA 6 University of Pittsburgh School of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundCardiac arrest survivorship refers to the lived experience of long?term survivors of cardiac arrest and the many postdischarge challenges they experience. We aimed to gather a nuanced understanding of these (...) (Journal of the American Heart Association)
13:24
Single?Center Experience of Hybrid Pulmonary Valve Replacement Using Left Anterior Thoracotomy With Pulmonary Artery Plication in Patients With Large Right Ventricular Outflow Tract - Kaitlin Carr, Bassel Mohmmad Nijres , Jimmy J. Windsor , Yuki Nakamura , Mohsen Karimi , Marco Ricci , and Osamah Aldoss 1 Division of Pediatric Cardiology University of Iowa Stead Family Children’s Hospital Iowa City IA 2 Division of Pediatric Anesthesia, Department of Anesthesia University of Iowa Iowa City IA 3 Department of Cardiothoracic Surgery University of Iowa Iowa City IA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundUntil recently, a large right ventricle outflow tract interfered with the feasibility of standard transcatheter pulmonary valve replacement (PVR). We are describing our experience using a hybrid approach (...) (Journal of the American Heart Association)
13:24
Primary Aldosteronism Screening Rates Differ with Sex, Race, and Comorbidities - Adina F. Turcu, Winnie Nhan , Seda Grigoryan , Lei Zhang , Caitlin Urban , Haiping Liu , Lynn Holevinski , and Lili Zhao 1 Division of Metabolism, Endocrinology, and Diabetes University of Michigan Ann Arbor MI 2 School of Public Health University of Michigan Ann Arbor MI 3 Michigan State University College of Human Medicine East Lansing MI 4 University of Michigan Medical School, Data Office for Clinical and Translational Research Ann Arbor MI J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundPrimary aldosteronism (PA) is a common but under?recognized cause of secondary hypertension. Data directly comparing screening rates across single and overlapping indications are lacking.Methods and (...) (Journal of the American Heart Association)
13:23
Hsa_circ_0016070/micro?340?5p Axis Accelerates Pulmonary Arterial Hypertension Progression by Upregulating TWIST1 Transcription Via TCF4/??Catenin Complex - Chun?Xia Huang, Zhi?Xin Jiang , Da?Yong Du , Zhi?Min Zhang , Yang Liu , and Yun?Tian Li 1 The Second School of Clinical Medicine Southern Medical University Guangzhou Guangdong Province China 2 Department of Cardiology 305 Hospital of PLA Beijing China 3 Shanxi Medical University Linfen Peoples’ Hospital Linfen Shanxi Province China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundHypoxia is considered a major leading cause of pulmonary hypertension (PH). In this study, the roles and molecular mechanism of circ_0016070 in PH were studied.Methods and ResultsThe expression of (...) (Journal of the American Heart Association)
03:00
Circling In on Pulmonary Arterial Hypertension: Is It Time to Consider Circular RNA circ_0016070 as a Biomarker and Target for Therapy? - Laszlo Farkas, and Elena A. Goncharova 1 Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Davis Heart and Lung Research Institute The Ohio State University Columbus OH 2 Division of Pulmonary, Critical Care and Sleep Medicine, Lung Center University of California, Davis School of Medicine Davis CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. (Journal of the American Heart Association)

6 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

03:35
Correction to: Loss of Endothelial Hypoxia Inducible Factor?Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)

5 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:20
Intensity of and Adherence to Lipid?Lowering Therapy as Predictors of Major Adverse Cardiovascular Outcomes in Patients With Coronary Heart Disease - Faizan Mazhar, Paul Hjemdahl , Catherine M. Clase , Kristina Johnell , Tomas Jernberg , Arvid Sjölander , and Juan Jesus Carrero 1 Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden 2 Department of Medicine Solna, Clinical Epidemiology Unit, Karolinska Institutet and Clinical Pharmacology Karolinska University Hospital Stockholm Sweden 3 Department of Medicine and Health Research Methods, Evidence and Impact McMaster University Ontario 4 Department of Clinical Sciences Danderyd University Hospital, Karolinska Institutet Stockholm Sweden 5 Division (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundThe effectiveness of lipid?lowering therapy (LLT) is affected by both intensity and adherence. This study evaluated the associations of LLT intensity, adherence, and the combination of these 2 aspects of LLT (...) (Journal of the American Heart Association)
13:19
Clinicians' Approach to Patent Foramen Ovale Closure after Stroke: Comparing Cardiologists and Neurologists - Farhan Khan, Paul Fiorilli , Steven R. Messé , Scott E. Kasner , Laith A. Derbas , Clifford J. Kavinsky , and Christopher G. Favilla 1 Department of Neurology University of Pennsylvania Philadelphia PA 2 Department of Cardiology University of Pennsylvania Philadelphia PA 3 Division of Cardiovascular Medicine Rush University Medical Center Chicago IL J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundEvidence from randomized trials and updated professional society guidelines supports patent foramen ovale (PFO) closure after cryptogenic stroke in select patients. It is unclear how this has been (...) (Journal of the American Heart Association)
13:19
Association of the Coexistence of Somnipathy and Diabetes With the Risks of Cardiovascular Disease Events, Stroke, and All?Cause Mortality: A Systematic Review and Meta?analysis - Xiu Hong Yang, Bao Long Zhang , Yun Cheng , Shun Kun Fu , and Hui Min Jin 1 Division of Nephrology, Shanghai Pudong Hospital Fudan University Pudong Medical Center Shanghai China 2 The Institutes of Biomedical Sciences (IBS) Fudan University Shanghai China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundSomnipathy and diabetes are independently associated with an increased risk of cardiovascular disease (CVD). However, whether a combination of both conditions is associated with a higher risk of CVD events (...) (Journal of the American Heart Association)
13:19
Interventions in Adults With Repaired Coarctation of the Aorta - Viktor Meidell Blylod, Daniel Rinnström , Johanna Pennlert , Ellen Ostenfeld , Mikael Dellborg , Peder Sörensson , Christina Christersson , Ulf Thilén , and Bengt Johansson 1 Department of Public Health and Clinical Medicine Umeå University Umeå Sweden 2 Department of Surgical and Perioperative Sciences Umeå University Umeå Sweden 3 Department of Clinical Sciences Lund Clinical Physiology, Lund University Lund Sweden 4 Department of Molecular and Clinical Medicine University of Gothenburg Gothenburg Sweden 5 Department of Medicine Solna Karolinska Institutet Stockholm Sweden 6 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundCoarctation of the aorta coexists with other cardiac anomalies and has long?term complications, including recoarctation, which may require intervention after the primary coarctation repair. This study aims (...) (Journal of the American Heart Association)
13:18
Concomitant Use of Diltiazem With Direct Oral Anticoagulants and Bleeding Risk in Atrial Fibrillation - Yunwen Xu, Alex R. Chang , Lesley A. Inker , Mara McAdams?DeMarco , Morgan E. Grams , and Jung?Im Shin 1 Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD 2 Division of Nephrology Geisinger Health System Danville PA 3 Division of Nephrology, Department of Internal Medicine Tufts Medical Center Boston MA 4 Department of Surgery New York University Grossman School of Medicine and Langone Health New York NY 5 Department of Population Health New York University Grossman School of Medicine and Langone Health New York NY 6 Department of Medicine New York (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundDiltiazem, a moderate cytochrome P450 3A4 isozyme/P?glycoprotein inhibitor, may potentiate the bleeding risk of direct oral anticoagulants (DOACs) through pharmacokinetic interactions. We evaluated the (...) (Journal of the American Heart Association)
13:18
Initiation of Dialysis Is Associated With Impaired Cardiovascular Functional Capacity - Eliott Arroyo, Peter E. Umukoro , Heather N. Burney , Yang Li , Xiaochun Li , Kathleen A. Lane , S. Jawad Sher , Tzong?shi Lu , Sharon M. Moe , Ranjani Moorthi , Andrew R. Coggan , Gordon McGregor , Thomas F. Hiemstra , Daniel Zehnder , and Kenneth Lim 1 Division of Nephrology and Hypertension Department of Medicine Indiana University School of Medicine Indianapolis IN 2 Department of Biostatistics and Health Data Science Indiana University School of Medicine Indianapolis IN 3 Department of Nephrology Hendricks Regional Health Danville IN 4 Renal Division Department of Medicine Brigham (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundThe transition to dialysis period carries a substantial increased cardiovascular risk in patients with chronic kidney disease. Despite this, alterations in cardiovascular functional capacity during this (...) (Journal of the American Heart Association)
13:17
Age?Independent Cardiac Protection by Pharmacological Activation of Beclin?1 During Endotoxemia and Its Association With Energy Metabolic Reprograming in Myocardium—A Targeted Metabolomics Study - Matthew Kim, Azadeh Nikouee , Raymond Zou , Di Ren , Zhibin He , Ji Li , Lu Wang , Danijel Djukovic , Daniel Raftery , Hayley Purcell , Daniel Promislow , Yuxiao Sun , Mohammad Goodarzi , Qing?Jun Zhang , Zhi?Ping Liu , and Qun Sophia Zang 1 Department of Surgery, Burn & Shock Trauma Research Institute Loyola University Chicago Stritch School of Medicine Maywood IL 2 Department of Biological Sciences Rice University Houston TX 3 Department of Surgery University of South Florida Tampa FL 4 Department of Environmental and Occupational Health Sciences University of Washington Seattle WA 5 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundWe showed that Beclin?1?dependent autophagy protects the heart in young and adult mice that underwent endotoxemia. Herein, we compared the potential therapeutic effects of Beclin?1 activating peptide, (...) (Journal of the American Heart Association)
13:17
Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial - Alice H. Lichtenstein, Penny M. Kris?Etherton , Kristina S. Petersen , Nirupa R. Matthan , Samuel Barnes , Mara Z. Vitolins , Zhaoping Li , Joan Sabaté , Sujatha Rajaram , Shilpy Chowdhury , Kristin M. Davis , Jean Galluccio , Cheryl H. Gilhooly , Richard S. Legro , Jason Li , Laura Lovato , Letitia H. Perdue , Gayle Petty , Anna M. Rasmussen , Gina Segovia?Siapco , Rawiwan Sirirat , April Sun , and David M. Reboussin 1 JM USDA Human Nutrition Center on Aging, Tufts University Boston MA 2 Department of Nutritional Sciences Pennsylvania State University State College PA 3 Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundExcess visceral adiposity is associated with increased risk of cardiometabolic disorders. Short?term well?controlled clinical trials suggest that regular avocado consumption favorably affects body weight, (...) (Journal of the American Heart Association)
13:16
Chronic Kidney Disease Is Associated With Increased Cardiac Corin Expression But Decreased Proatrial Natriuretic Peptide Conversion Activity - Shang?Feng Yang, Szu?Yuan Li , Feng?Yen Lin , Tsung?Han Hsieh , Po?Hsun Huang , and Shing?Jong Lin 1 Division of Nephrology, Department of Medicine Cheng Hsin General Hospital Taipei Taiwan 2 Institute of Clinical Medicine National Yang Ming Chiao Tung University Taipei Taiwan 3 Division of Nephrology, Department of Medicine Taipei Veterans General Hospital Taipei Taiwan 4 School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan 5 Division of Cardiology and Cardiovascular Research Center, Department of Internal Medicine Taipei Medical University Hospital Taipei Taiwan 6 (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundChronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease. Corin converts proatrial natriuretic peptide into its active form after being activated by PCSK6 (proprotein (...) (Journal of the American Heart Association)
13:16
Trends in Medicare Payments for Beneficiaries With Aortic Stenosis - Pieter A. J. van Bakel, Yunus Ahmed , Hechuan Hou , Devraj Sukul , Donald S. Likosky , Joost A. van Herwaarden , Himanshu J. Patel , and Michael P. Thompson 1 Department of Cardiac Surgery University of Michigan Ann Arbor MI 2 Department of Vascular Surgery University Medical Center Utrecht Utrecht the Netherlands 3 Division of Cardiology, Department of Internal Medicine University of Michigan Ann Arbor MI J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundAortic stenosis (AS) is the most common form of valvular heart disease with an increasing prevalence. Management of AS has changed dramatically with the introduction of transcatheter aortic valve (...) (Journal of the American Heart Association)
13:16
Cause?Specific Mortality in Patients During Long?Term Follow?Up After Atrial Switch for Transposition of the Great Arteries - Annette Schophuus Jensen, Troels Højsgaard Jørgensen , Christina Christersson , Edit Nagy , Juha Sinisalo , Eva Furenäs , Ola Gjesdal , Peter Eriksson , Niels Vejlstrup , Bengt Johansson , Joanna Hlebowicz , Gottfried Greve , Mikael Dellborg , Helge Skulstad , Per Kvidal , Eero Jokinen , Heikki Sairanen , Ulf Thilén , and Lars Søndergaard 1 Department of Cardiology Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark 2 Department of Medical Sciences, Cardiology Uppsala University Uppsala Sweden 3 Department of Medicine, Heart and Vascular Theme, Karolinska University Hospital (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundLittle is known about the cause of death (CoD) in patients with transposition of the great arteries palliated with a Mustard or Senning procedure. The aim was to describe the CoD for patients with the (...) (Journal of the American Heart Association)
13:15
Association Between Sleep Microstructure and Incident Hypertension in a Population?Based Sample: The HypnoLaus Study - Mathieu Berger, Andrew Vakulin , Camila Hirotsu , Nicola Andrea Marchi , Geoffroy Solelhac , Virginie Bayon , Francesca Siclari , José Haba?Rubio , Julien Vaucher , Peter Vollenweider , Pedro Marques?Vidal , Bastien Lechat , Peter G. Catcheside , Danny J. Eckert , Robert J. Adams , Sarah Appleton , and Raphael Heinzer 1Center for Investigation and Research in Sleep Department of Medicine Lausanne University Hospital and University of Lausanne Lausanne Switzerland 2Flinders Health and Medical Research Institute: Sleep Health/Adelaide Institute for Sleep HealthFlinders UniversityCollege of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundPoor sleep quality is associated with increased incident hypertension. However, few studies have investigated the impact of objective sleep structure parameters on hypertension. This study investigated the (...) (Journal of the American Heart Association)
13:14
Association of Pulmonary Function With Late?Life Cardiac Function and Heart Failure Risk: The ARIC Study - Sergio H. R. Ramalho, Brian L. Claggett , George R. Washko , Raul San Jose Estepar , Patricia P. Chang , Dalane W. Kitzman , Gerson Cipriano Junior , Scott D. Solomon , Hicham Skali , and Amil M. Shah 1Division of Cardiovascular Medicine Brigham and Women’s Hospital Boston MA 2Health Sciences and Technologies Program – University of Brasilia Brasília Brazil 3Division of Pulmonary and Critical Care Medicine Brigham and Women’s Hospital Boston MA 4Department of Radiology Brigham and Women’s Hospital Boston MA 5University of North Carolina Chapel Hill NC 6Wake Forest School of Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundPulmonary and cardiac functions decline with age, but the associations of pulmonary dysfunction with cardiac function and heart failure (HF) risk in late life is not known. We aimed to determine the (...) (Journal of the American Heart Association)
13:14
Gravitational Dose?Response Curves for Acute Cardiovascular Hemodynamics and Autonomic Responses in a Tilt Paradigm - Richard S. Whittle, Nathan Keller , Eric A. Hall , Hrudayavani S. Vellore , Lindsay M. Stapleton , Katherine H. Findlay , Bonnie J. Dunbar , and Ana Diaz?Artiles 1Department of Aerospace Engineering Texas A&M University College Station TX 2Department of Health and Kinesiology Texas A&M University College Station TX 3Department of Biomedical Engineering Texas A&M University College Station TX 4Independent Researcher College Station TX J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundThe cardiovascular system is strongly dependent on the gravitational environment. Gravitational changes cause mechanical fluid shifts and, in turn, autonomic effectors influence systemic circulation and (...) (Journal of the American Heart Association)
13:13
Correction to: One?Month Dual Antiplatelet Therapy After Bioresorbable Polymer Everolimus?Eluting Stents in High Bleeding Risk Patients J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
13:12
Correction to: Ischemic Stroke Severity and Mortality in Patients With and Without Atrial Fibrillation J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
13:12
Correction to: Clinical Impact of Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention in Patients Treated With Potent P2Y12 inhibitors – a VALIDATE?SWEDEHEART Substudy J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)

4 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

11:06
Highlights in ASCVD Primary Prevention for 2021 - Tamar S. Polonsky, Amit Khera , Michael D. Miedema , Douglas D. Schocken , and Peter W. F. Wilson 1 Department of Medicine University of Chicago Medicine Chicago IL 2 Department of Medicine University of Texas, Southwestern Dallas TX 3 Allina Health Minneapolis MN 4 Department of Medicine Duke University Durham NC 5 Department of Medicine Emory University Atlanta GA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. This review examines key studies published in 2021 that are related to primary prevention of atherosclerotic cardiovascular disease (ASCVD). Major randomized clinical trials (RCTs) concerning traditional risk factors (...) (Journal of the American Heart Association)

29 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:08
Alcohol Consumption Is Associated With Postablation Recurrence but Not Changes in Atrial Substrate in Patients With Atrial Fibrillation: Insight from a High?Density Mapping Study - Yuichiro Sagawa, Yasutoshi Nagata , Naoyuki Miwa , Takanori Yamaguchi , Keita Watanabe , Masakazu Kaneko , Tomofumi Nakamura , Toshihiro Nozato , Takashi Ashikaga , Masahiko Goya , and Tetsuo Sasano 1 Department of Cardiology Japanese Red Cross Musashino Hospital Tokyo Japan 2 Cardiovascular Center Tsuchiura Kyodo Hospital Tsuchiura Japan 3 Department of Cardiovascular Medicine Saga University Saga Japan 4 Department of Cardiovascular Medicine Tokyo Medical and Dental University Tokyo (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe association between alcohol consumption, atrial substrate, and outcomes after atrial fibrillation (AF) ablation remains controversial. This study evaluated the impacts of drinking on left atrial (...) (Journal of the American Heart Association)
12:45
Bidirectional Longitudinal Relationships Between Arterial Stiffness and Hypertension Are Independent of Those Between Arterial Stiffness and Diabetes: A Large?Scale Prospective Observational Study in Employees of a Japanese Company - Hiroki Nakano, Kazuki Shiina , Takamichi Takahashi , Masatsune Fujii , Yoichi Iwasaki , Chisa Matsumoto , Akira Yamashina , Taishiro Chikamori , and Hirofumi Tomiyama 1 Department of Cardiology Tokyo Medical University Tokyo Japan 2 Division of Preemptive Medicine for Vascular Damage Tokyo Medical University Tokyo Japan 3 Department of Nursing Kiryu University Gunma Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundHypertension and diabetes frequently coexist; however, it has not yet been clarified if the bidirectional longitudinal relationships between arterial stiffness and hypertension are independent of those (...) (Journal of the American Heart Association)
12:45
Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality - Patricia A. Pellikka, Ratnasari Padang , Christopher G. Scott , Shannon M. E. Murphy , Rosalind Fabunmi , and Jeremy J. Thaden 1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN 2 Department of Quantitative Health Sciences Mayo Clinic Rochester MN 3 Edwards Lifesciences Irvine CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundMany patients with symptomatic severe aortic stenosis do not undergo aortic valve replacement (AVR) despite clinical guidelines. This study analyzed the association of managing provider type with cardiac (...) (Journal of the American Heart Association)
12:45
Novel Risk Prediction Model to Determine Adverse Heart Failure Outcomes in Arrhythmogenic Right Ventricular Cardiomyopathy - Shi Chen, Liang Chen , Ardan M. Saguner , Kai Chen , Deniz Akdis , Alessio Gasperetti , Corinna Brunckhorst , Hanwei Tang , Guangran Guo , Man Rao , Xiangjie Li , Jiangping Song , Firat Duru , and Shengshou Hu 1 State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China 2 University Heart Center Zurich Zurich Switzerland 3 Center for Integrative Human Physiology University of Zurich Zurich Switzerland 4 School of Statistics and Data Science Nankai University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundPatients with arrhythmogenic right ventricular cardiomyopathy are at risk for life?threatening ventricular tachyarrhythmias, but progressive heart failure (HF) may occur in later stages of disease. This study (...) (Journal of the American Heart Association)
12:45
Neuropeptide?Y Levels in ST?Segment–Elevation Myocardial Infarction: Relationship With Coronary Microvascular Function, Heart Failure, and Mortality - Thomas Gibbs, Nidi Tapoulal , Mayooran Shanmuganathan , Matthew K. Burrage , Alessandra Borlotti , Adrian P. Banning , Robin P. Choudhury , Stefan Neubauer , Rajesh K. Kharbanda , Vanessa M. Ferreira , Keith M. Channon , and Neil Herring 1 Department of Physiology, Anatomy and Genetics, Burdon Sanderson Cardiac Science Centre University of Oxford United Kingdom 2 Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence University of Oxford United Kingdom 3 Oxford Acute Vascular Imaging Centre University of Oxford United (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe sympathetic cotransmitter, neuropeptide Y (NPY), is released into the coronary sinus during ST?segment–elevation myocardial infarction and can constrict the coronary microvasculature. We sought to (...) (Journal of the American Heart Association)
12:44
Inhibiting Succinate Release Worsens Cardiac Reperfusion Injury by Enhancing Mitochondrial Reactive Oxygen Species Generation - Alexander S. Milliken, Sergiy M. Nadtochiy , and Paul S. Brookes 1 Department of Pharmacology and Physiology University of Rochester Medical Center Rochester NY 2 Department of Anesthesiology and Perioperative Medicine University of Rochester Medical Center Rochester NY J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe metabolite succinate accumulates during cardiac ischemia. Within 5 minutes of reperfusion, succinate returns to baseline levels via both its release from cells and oxidation by mitochondrial complex II. (...) (Journal of the American Heart Association)
12:44
B?Type Natriuretic Peptide and Long?Term Cardiovascular Mortality in Patients With Coronary Heart Disease - Ralph A. H. Stewart, Adrienne Kirby , Harvey D. White , Simone L. Marschner , Malcolm West , Peter L. Thompson , David Sullivan , Edward Janus , David Hunt , Leonard Kritharides , Anthony Keech , John Simes , and Andrew M. Tonkin 1 Green Lane Cardiovascular Service Auckland City Hospital Auckland New Zealand 2 National Health and Medical Research Council Clinical Trials Centre University of Sydney Camperdown Australia 3 Department of Medicine University of Queensland Brisbane Australia 4 School of Population Health University of Western Australia Perth Australia 5 Department of Clinical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe plasma concentration of B?type natriuretic peptide (BNP) is a strong predictor of adverse cardiovascular events. The aim of this study was to determine whether the association between plasma BNP (...) (Journal of the American Heart Association)
12:44
Utility of Updated Japanese Circulation Society Guidelines to Diagnose Isolated Cardiac Sarcoidosis - Kimi Sato, Naoto Kawamatsu , Masayoshi Yamamoto , Tomoko Machino?Ohtsuka , Tomoko Ishizu , and Masaki Ieda 1 Department of Cardiology, Faculty of Medicine University of Tsukuba Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundIn the population with cardiac sarcoidosis (CS), approximately one third lacks extracardiac involvement and is considered to have isolated CS. Recently, the Japanese Circulation Society updated the (...) (Journal of the American Heart Association)
12:44
Left Ventricular Diastolic Dysfunction and Progression of Chronic Kidney Disease: Analysis of KNOW?CKD Data - Eunjeong Kang, Sung Woo Lee , Hyunjin Ryu , Minjung Kang , Seonmi Kim , Sue K. Park , Ji Yong Jung , Kyu?Beck Lee , Seung Hyeok Han , Curie Ahn , and Kook?Hwan Oh 1 Department of Internal Medicine Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine Seoul South Korea 2 Department of Internal Medicine Uijeongbu Eulji University Medical Center, Uijeongbu?si Gyeonggi?do South Korea 3 Department of Internal Medicine Seoul National University College of Medicine Seoul South Korea 4 Department of Preventive Medicine Seoul National University College of Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundFew studies have examined the association between the early diastolic mitral inflow velocity/early diastolic mitral annulus velocity ratio (E/e’) and chronic kidney disease progression.Methods and ResultsWe (...) (Journal of the American Heart Association)
12:44
Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism - Tomomi Ueda, Yuya Tsurutani , Jun Osada , Kosuke Inoue , Yoshitomo Hoshino , Masato Ono , Kazuki Nakai , Jun Saito , Kazuhiko Yumoto , and Tetsuo Nishikawa 1 Endocrinology and Diabetes Center Yokohama Rosai Hospital Yokohama Japan 2 Department of Cardiovascular Medicine Yokohama Rosai Hospital Yokohama Japan 3 Department of Social Epidemiology, Graduate School of Medicine Kyoto University Kyoto Japan 4 Nishikawa Clinic Yokohama Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundPrimary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement. A few studies have compared the (...) (Journal of the American Heart Association)
12:44
Late Outcomes of Patients With Prehospital ST?Segment Elevation and Appropriate Cardiac Catheterization Laboratory Nonactivation - Amir Faour, Reece Pahn , Callum Cherrett , Oliver Gibbs , Karen Lintern , Christian J. Mussap , Rohan Rajaratnam , Dominic Y. Leung , David A. Taylor , Steven C. Faddy , Sidney Lo , Craig P. Juergens , and John K. French 1 Department of Cardiology, Liverpool Hospital Sydney New South Wales 2 The University of New South Wales Sydney New South Wales 3 Western Sydney University Sydney New South Wales 4 Ingham Institute Sydney New South Wales 5 New South Wales Ambulance Sydney New South (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundPatients with suspected ST?segment–elevation myocardial infarction (STEMI) and cardiac catheterization laboratory nonactivation (CCL?NA) or cancellation have reportedly similar crude and higher adjusted risks (...) (Journal of the American Heart Association)
12:44
Diastolic Filling Time, Chronotropic Response, and Exercise Capacity in Heart Failure and Preserved Ejection Fraction With Sinus Rhythm - Kazuki Kagami, Masaru Obokata , Tomonari Harada , Toshimitsu Kato , Naoki Wada , Takeshi Adachi , and Hideki Ishii 1 Department of Cardiovascular Medicine Gunma University Graduate School of Medicine Maebashi Gunma Japan 2 Division of Cardiovascular Medicine National Defense Medical College Tokorozawa, Saitama Japan 3 Department of Rehabilitation Medicine Gunma University Graduate School of Medicine Maebashi Gunma Japan J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundExercise?induced high heart rate may impair exercise tolerance by reducing diastolic filling time and ventricular filling in heart failure with preserved ejection fraction (HFpEF). Given the importance of (...) (Journal of the American Heart Association)
12:43
Predicting Heart Failure in Arrhythmogenic Right Ventricular Cardiomyopathy - Weijia Wang, and Hugh Calkins 1 Division of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. (Journal of the American Heart Association)
12:43
Association Between High?Sensitivity C?Reactive Protein and Prognosis in Different Periods After Ischemic Stroke or Transient Ischemic Attack - Yu Wang, Jiejie Li , Yuesong Pan , Mengxing Wang , Xia Meng , and Yongjun Wang 1 Department of Neurology Beijing Tiantan Hospital, Capital Medical University Beijing China 2 China National Clinical Research Center for Neurological Diseases Beijing China 3 Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical Sciences Beijing China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe aim of this study was to investigate the association between hsCRP (high?sensitivity C?reactive protein) and prognosis over time after stroke onset.Methods and ResultsIn this prespecified prospective (...) (Journal of the American Heart Association)
12:43
Translating Clinical Guidelines Into Care Delivery Innovation: The Importance of Rigorous Methods for Generating Evidence - Adam N. Berman, and Jason H. Wasfy 1 Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital Harvard Medical School Boston MA 2 Cardiology Division, Department of Medicine, Massachusetts General Hospital Harvard Medical School Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. (Journal of the American Heart Association)
12:43
Misdiagnosis of Thoracic Aortic Emergencies Occurs Frequently Among Transfers to Aortic Referral Centers: An Analysis of Over 3700 Patients - George J. Arnaoutakis, Takuya Ogami , Edgar Aranda?Michel , Yancheng Dai , Reed Holmes , Thomas M. Beaver , Derek Serna?Gallegos , Tomas D. Martin , Forozan Navid , Sarah Yousef , and Ibrahim Sultan 1 University of Florida Health Gainsville FL 2 Division of Cardiac Surgery, Department of Cardiothoracic Surgery University of Pittsburgh Pittsburgh PA USA 3 Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundAcute aortic syndromes may be prone to misdiagnosis by nonreferral aortic centers with less diagnostic experience. We evaluated regional variability in these misdiagnosis trends among patients transferred to (...) (Journal of the American Heart Association)
12:42
Sex?Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca2+ Handling - Celio Damacena de Angelis, Benney T. Endoni , Daniel Nuno , Kathryn Lamping , Johannes Ledolter , Olha M. Koval , and Isabella M. Grumbach 1 Department of Internal Medicine, Abboud Cardiovascular Research Center University of Iowa Iowa City IA 2 Department of Pharmacology Carver College of Medicine University of Iowa Iowa City IA 3 Tippie College of Business University of Iowa Iowa City IA 4 College of Liberal Arts and Sciences University of Iowa Iowa City IA 5 Redox and Radiation Biology Program Holden Comprehensive Cancer Center University of Iowa Iowa City IA 6 Iowa City VA Healthcare (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundSex?specific differences in vasodilation are mediated in part by differences in cytosolic Ca2+handling, but how variations in mitochondrial Ca2+contributes to this effect remains unknown. Here, we (...) (Journal of the American Heart Association)
12:42
Survival Probability and Survival Benefit Associated With Primary Prevention Implantable Cardioverter?Defibrillator Generator Changes - Kenneth C. Bilchick, Yongfei Wang , Jeptha P. Curtis , Ramin Shadman , Todd F. Dardas , Inder Anand , Lars H. Lund , Ulf Dahlström , Ulrik Sartipy , and Wayne C. Levy 1 Department of Medicine University of Virginia Health System Charlottesville VA 2 Center for Outcomes Research and Evaluation Yale?New Haven Hospital New Haven CT 3 Department of Internal Medicine Yale University New Haven CT 4 Southern California Permanente Medical Group Los Angeles CT 5 Department of Medicine University of Washington Seattle WA 6 University of Minnesota Minneapolis MN 7 Department of Medicine/Cardiology (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundAs patients derive variable benefit from generator changes (GCs) of implantable cardioverter?defibrillators (ICDs) with an original primary prevention (PP) indication, better predictors of outcomes are (...) (Journal of the American Heart Association)
12:41
Colchicine Ameliorates Dilated Cardiomyopathy Via SIRT2?Mediated Suppression of NLRP3 Inflammasome Activation - Xuan Sun, Junfeng Duan , Chenyi Gong , Yuting Feng , Jiaxin Hu , Rong Gu , and Biao Xu 1 State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital Medical School of Nanjing University Nanjing China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundDilated cardiomyopathy remains a leading cause of heart failure worldwide. Immune inflammation response is recognized as a significant player in the progression of heart failure; however, immunomodulatory (...) (Journal of the American Heart Association)
12:40
Hospital?Level Variation in Ticagrelor Use in Patients With Acute Coronary Syndrome - Aya F. Ozaki, Cynthia A. Jackevicius , Alice Chong , Maneesh Sud , Jiming Fang , Peter C. Austin , and Dennis T. Ko 1School of Pharmacy & Pharmaceutical Sciences University of California Irvine CA United States 2College of Pharmacy Western University of Health Sciences Pomona CA United States 3Veterans Affairs Greater Los Angeles Healthcare System Los Angeles CA United States 4ICES Toronto Canada 5University of Toronto Ontario Canada 6Schulich Heart Centre Sunnybrook Health Sciences Centre Toronto Ontario (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundDespite improved outcomes associated with ticagrelor compared with clopidogrel in acute coronary syndrome (ACS), many studies have demonstrated slow adoption of ticagrelor in the United States because of its (...) (Journal of the American Heart Association)
12:40
Patent Ductus Arteriosus Stent Versus Surgical Aortopulmonary Shunt for Initial Palliation of Cyanotic Congenital Heart Disease with Ductal?Dependent Pulmonary Blood Flow: A Systematic Review and Meta?Analysis - Stephanie Y. Tseng, Vien T. Truong , Daniel Peck , Sneha Kandi , Samuel Brayer , Don P. Jason , Wojciech Mazur , Garick D. Hill , Awais Ashfaq , Bryan H. Goldstein , and Tarek Alsaied 1 The Heart Center Nationwide Children’s Hospital Columbus OH 2 The Heart Institute, Cincinnati Children’s Hospital Medical Center Cincinnati OH 3 The Christ Hospital Health Network Cincinnati OH 4 Northeast Ohio Medical University Rootstown OH 5 University of Cincinnati College of Medicine Cincinnati OH 6 Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH 7 Heart Institute (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundIn patients with ductal?dependent pulmonary blood flow, initial palliation includes catheter?based patent ductus arteriosus (PDA) stent or surgical aortopulmonary shunt (APS). This meta?analysis aimed to (...) (Journal of the American Heart Association)
12:40
Mortality Risk in Takotsubo Syndrome Versus Myocarditis - Alan C. Kwan, Jesse Navarrette , Patrick Botting , Melanie T. Chen , Janet Wei , C. Noel Bairey Merz , Joseph E. Ebinger , and Susan Cheng 1Department of Cardiology Barbra Streisand Women's Heart Center Smidt Heart InstituteCedars Sinai Medical Center Los Angeles CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. (Journal of the American Heart Association)
12:39
Multifaceted Intervention to Improve P2Y12 Inhibitor Adherence After Percutaneous Coronary Intervention: A Stepped Wedge Trial - P. Michael Ho, Colin I. O’Donnell , Marina McCreight , Anthony A. Bavry , Hayden B. Bosworth , Saket Girotra , P. Michael Grossman , Christian Helfrich , Faisal Latif , David Lu , Michael Matheny , Kreton Mavromatis , Jose Ortiz , Amitabh Parashar , Devona M. Ratliff , Gary K. Grunwald , Michael Gillette , and Hani Jneid 1 Cardiology Section Rocky Mountain Regional VA Medical Center Aurora CO 2 Department of Medicine University of Colorado School of Medicine Aurora CO 3 Denver?Seattle Center of Innovation for Veteran Centered and Value Driven Care Rocky Mountain Regional VA Medical Center (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundP2Y12 inhibitor medications are critical following percutaneous coronary intervention (PCI); however, adherence remains suboptimal. Our objective was to assess the effectiveness of a multifaceted (...) (Journal of the American Heart Association)

22 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:33
Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart - Keqiang Yan, Zhanlong Mei , Jingjing Zhao , Md Aminul Islam Prodhan , Detlef Obal , Kartik Katragadda , Benjamin Doelling , David Hoetker , Dheeraj Kumar Posa , Liqing He , Xinmin Yin , Jasmit Shah , Jianmin Pan , Shesh Rai , Pawel Konrad Lorkiewicz , Xiang Zhang , Siqi Liu , Aruni Bhatnagar , and Shahid P. Baba 1 Beijing Institute of Genomics Chinese Academy of Sciences, Beishan Industrial Zone Shenzhen China 2 Diabetes and Obesity Center University of Louisville KY 3 Christina Lee Brown Envirome Institute University of Louisville KY USA 4 Department of Chemistry University of Louisville (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundHistidyl dipeptides such as carnosine are present in a micromolar to millimolar range in mammalian hearts. These dipeptides facilitate glycolysis by proton buffering. They form conjugates with reactive (...) (Journal of the American Heart Association)
12:33
Exploring Health Care Providers' Experiences of Providing Collaborative Palliative Care for Patients With Advanced Heart Failure At Home: A Qualitative Study - Cassandra Graham, Rebecca Schonnop , Tieghan Killackey , Dio Kavalieratos , Shirley H. Bush , Leah Steinberg , Susanna Mak , Kieran Quinn , and Sarina R. Isenberg 1 Division of Palliative Medicine, Department of Medicine University of Toronto Toronto Canada 2 Division of Palliative Care University Health Network Toronto Canada 3 Department of Emergency Medicine University of Alberta Edmonton Canada 4 Department of Emergency Medicine Royal Alexandra Hospital Edmonton Canada 5 Child Health Evaluative Sciences The Hospital for Sick Children Toronto Canada 6 Division of Palliative Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe HeartFull Collaborative is a regionally organized model of care which involves specialist palliative care and cardiology health care providers (HCPs) in a collaborative, home?based palliative care (...) (Journal of the American Heart Association)
12:33
Temporal Changes in Beat?to?Beat Variability of Repolarization Predict Imminent Nonsustained Ventricular Tachycardia in Patients With Ischemic and Nonischemic Dilated Cardiomyopathy - Matthew Amoni, Sebastian Ingelaere , Jonathan Moeyersons , Bert Vandenberk , Piet Claus , Robin Lemmens , Sabine Van Huffel , Karin Sipido , Carolina Varon , and Rik Willems 1 Cardiology University Hospitals Leuven Leuven Belgium 2 Experimental Cardiology, Department of Cardiovascular Sciences University of Leuven Belgium 3 STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Department of Electrical Engineering University of Leuven Belgium 4 Imaging and Cardiovascular Dynamics, Department of Cardiovascular Sciences KU Leuven Leuven Belgium 5 Neurology University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundAn increase in beat?to?beat variability of repolarization (BVR) predicts arrhythmia onset in experimental models, but its clinical translation is not well established. We investigated the temporal changes in (...) (Journal of the American Heart Association)
12:33
Quantification of Cardiac Adipose Tissue in Failing and Nonfailing Human Myocardium - Kyra K. Peczkowski, Mohammed A. Mashali , Nancy S. Saad , Austin Hare , Courtney M. Campbell , Bryan A. Whitson , Nahush A. Mokadam , and Paul M. L. Janssen 1 Department of Physiology and Cell Biology College of Medicine The Ohio State University Columbus OH 2 Dorothy M. Davis Heart and Lung Research Institute The Ohio State University Columbus OH 3 Department of Internal Medicine College of Medicine The Ohio State University Columbus OH 4 Division of Cardiac Surgery College of Medicine The Ohio State University Columbus (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundBecause body mass index (BMI) is generally used clinically to define obesity and to estimate body adiposity, BMI likely is positively correlated with epicardial adipose tissue (EAT) level. Based on (...) (Journal of the American Heart Association)
12:32
Safety and Efficacy of SSRIs in Improving Poststroke Recovery: A Systematic Review and Meta?Analysis - Heba M. Kalbouneh, Ahmad A. Toubasi , Farah H. Albustanji , Yazan Y. Obaid , and Layla M. Al?Harasis 1Department of Anatomy Faculty of Medicine University of Jordan Amman Jordan 2Faculty of Medicine University of Jordan Amman Jordan 3Faculty of Medicine Jordan University of Science and Technology Irbid Jordan J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundSeveral studies investigated the role of selective serotonin reuptake inhibitors (SSRIs) in improving poststroke recovery; thus, we have decided to conduct this systematic review and meta?analysis to (...) (Journal of the American Heart Association)
12:32
Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice - Jared M. McLendon, Xiaoming Zhang , Daniel S. Matasic , Mohit Kumar , Olha M. Koval , Isabella M. Grumbach , Sakthivel Sadayappan , Barry London , and Ryan L. Boudreau 1Department of Internal Medicine University of Iowa Carver College of Medicine Iowa City IA 2Abboud Cardiovascular Research Center University of Iowa Carver College of Medicine Iowa City IA 3Department of Molecular Physiology and Biophysics University of Iowa Carver College of Medicine Iowa City IA 4Department of Pharmacology and Systems Physiology University of Cincinnati OH 5Division of Cardiovascular Health and Disease (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundSorbin and SH3 domain containing 2 (Sorbs2) protein is a cytoskeletal adaptor with an emerging role in cardiac biology and disease; yet, its potential relevance to adult?onset cardiomyopathies remains (...) (Journal of the American Heart Association)
12:32
Aspirin Therapy on Prophylactic Anticoagulation for Patients Hospitalized With COVID?19: A Propensity Score?Matched Cohort Analysis of the HOPE?COVID?19 Registry - Francesco Santoro, Ivan J. Núñez?Gil , Enrica Vitale , María C. Viana?Llamas , Rodolfo Romero , Charbel Maroun Eid , Gisela Feltes Guzman , Victor Manuel Becerra?Muñoz , Inmaculada Fernández Rozas , Aitor Uribarri , Emilio Alfonso?Rodriguez , Marcos García Aguado , Jia Huang , Alex Fernando Castro Mejía , Juan Fortunato Garcia Prieto , Javier Elola , Fabrizio Ugo , Enrico Cerrato , Jaime Signes?Costa , Sergio Raposeiras Roubin , Jorge Luis Jativa Mendez , Carolina Espejo Paeres , Alvaro López Masjuan , Francisco Marin , Federico Guerra , Ibrahim El?Battrawy , Bernardo Cortese , Harish Ramakrishna (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundCOVID?19 is an infectious illness, featured by an increased risk of thromboembolism. However, no standard antithrombotic therapy is currently recommended for patients hospitalized with COVID?19. The aim of (...) (Journal of the American Heart Association)
12:32
Rheumatic Heart Disease Is a Neglected Disease Relative to Its Burden Worldwide: Findings From Global Burden of Disease 2019 - Seyyed?Hadi Ghamari, Mohsen Abbasi?Kangevari , Sahar Saeedi Moghaddam , Arya Aminorroaya , Negar Rezaei , Parnian Shobeiri , Zahra Esfahani , Mohammad?Reza Malekpour , Nazila Rezaei , Ali Ghanbari , Mohammad Keykhaei , Mohammadreza Naderian , Bagher Larijani , Mohamad Taghi Majnoon , Farshad Farzadfar , and Ali H. Mokdad 1Non?Communicable Diseases Research Center Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran Iran 2Tehran Heart CenterTehran University of Medical Sciences Tehran Iran 3Endocrinology and Metabolism Research Center (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundRheumatic heart disease (RHD) takes a heavy toll in low? and middle?income countries. We aimed to present worldwide estimates for the burden of the RHD during 1990 to 2019 using the GBD (Global Burden of (...) (Journal of the American Heart Association)
12:31
Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice - Qing Liang, Hu Xu , Min Liu , Lei Qian , Jin Yan , Guangrui Yang , and Lihong Chen 1Advanced Institute for Medical Sciences Dalian Medical University Dalian China 2School of Bioengineering Dalian University of Technology Dalian China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundMice with cardiomyocyte?specific deletion of Bmal1, a core clock gene, had spontaneous abnormal cardiac metabolism, dilated cardiomyopathy, and shortened lifespan. However, the role of cardiomyocyte Bmal1 in (...) (Journal of the American Heart Association)
12:31
Health State Utility Values in People With Stroke: A Systematic Review and Meta?Analysis - Raed A. Joundi, Joel Adekanye , Alexander A. Leung , Paul Ronksley , Eric E. Smith , Alexander D. Rebchuk , Thalia S. Field , Michael D. Hill , Stephen B. Wilton , and Lauren C. Bresee 1Department of Clinical Neurosciences University of Calgary Alberta Canada 2Division of Neurology Hamilton Health SciencesMcMaster University & Population Health Research Institute Hamilton Ontario Canada 3University of Calgary Calgary Alberta Canada 4University of British Columbia Vancouver British Columbia Canada 5Department of Community Health Sciences University of Calgary Alberta (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundHealth state utility values are commonly used to provide summary measures of health?related quality of life in studies of stroke. Contemporaneous summaries are needed as a benchmark to contextualize future (...) (Journal of the American Heart Association)
12:31
Racial and Ethnic Differences in Cardiac Rehabilitation Participation: Effect Modification by Household Income - Joshua Garfein, Emily N. Guhl , Gretchen Swabe , Akira Sekikawa , Emma Barinas?Mitchell , Daniel E. Forman , and Jared W. Magnani 1 Department of Medicine University of Pittsburgh School of Medicine Pittsburgh PA 2 Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA 3 Department of Epidemiology, Graduate School of Public Health University of Pittsburgh PA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundCardiac rehabilitation (CR) is associated with improved cardiovascular outcomes. Racial and ethnic differences in CR have been identified, but whether income may attenuate these disparities remains unknown. (...) (Journal of the American Heart Association)
12:31
Genetically?Proxied Levels of Vitamin D and Risk of Intracerebral Hemorrhage - Natalia Szejko, Julian N. Acosta , Cameron P. Both , Audrey Leasure , Charles Matouk , Lauren Sansing , Thomas M. Gill , Zhao Hongyu , Kevin Sheth , and Guido J. Falcone 1 Department of Neurology Yale School of Medicine New Haven CT 2 Department of Bioethics Medical University of Warsaw Poland 3 Department of Neurology Medical University of Warsaw Poland 4 Department of Neurosurgery Yale School of Medicine New Haven CT 5 Department of Internal Medicine, Geriatric Medicine Yale School of Medicine New Haven CT 6 Department of Biostatistics Yale School of Public Health New Haven (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe evidence linking vitamin D (VitD) levels and spontaneous intracerebral hemorrhage (ICH) remains inconclusive. We tested the hypothesis that lower genetically determined VitD levels are associated with (...) (Journal of the American Heart Association)
12:30
To Be or Not to Be: Surviving Immune?Mediated Fetal Heart Disease - Edgar Jaeggi, Lisa Hornberger , Bettina Cuneo , Anita J. Moon?Grady , Marie?Josée Raboisson , Jane Lougheed , Karim Diab , Wadi Mawad , and Earl Silverman 1Labatt Family Heart Centre The Hospital for Sick Children Toronto Ontario Canada 2Labatt Family Heart Centre Stollery Children’s Hospital University of Alberta Edmonton Alberta Canada 3Labatt Family Heart Centre Children’s Hospital Colorado Denver CO 4Labatt Family Heart Centre UCSF Benioff Children's Hospital San Francisco CA 5Labatt Family Heart Centre Centre Hospitalier Universitaire Sainte Justine Montréal Quebec Canada 6Labatt Family (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. (Journal of the American Heart Association)
12:30
To Be or Not to Be Treated: That Is the Question in Managing a Fetus With Cardiac Injury Exposed to Anti?SSA/Ro - Jill Buyon, Amit Saxena , Deborah Friedman , and Peter Izmirly 1Division of Rheumatology Department of Medicine New York University Grossman School of Medicine New York NY 2Department of Pediatrics New York Medical College Valhalla NY J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. (Journal of the American Heart Association)
12:30
Relationship of Sodium Intake With Granulocytes, Renal and Cardiovascular Outcomes in the Prospective EPIC?Norfolk Cohort - Eliane F. E. Wenstedt, Hessel Peters Sengers , S. Matthijs Boekholdt , Kay?Tee Khaw , Nicholas J. Wareham , Bert?Jan H. van den Born , and Liffert Vogt 1Department of Internal Medicine Section of Nephrology Amsterdam UMC University of AmsterdamAmsterdam Cardiovascular Sciences Amsterdam The Netherlands 2Amsterdam UMC University of AmsterdamCenter for Experimental and Molecular Medicine Amsterdam The Netherlands 3Amsterdam UMC The Amsterdam Institute for Infection and Immunity Amsterdam The Netherlands 4Department of Cardiology Amsterdam UMC University of Amsterdam The Netherlands (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundExperimental studies show that high?sodium intake affects the innate immune system, among others with increased circulating granulocytes. Whether this relationship exists on a population level and whether (...) (Journal of the American Heart Association)
12:29
Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium - Edoardo Bressi, Thomas C. Crawford , Frank M. Bogun , Xiaokui Gu , Kenneth A. Ellenbogen , Alexandra B. Chicos , Henri Roukoz , Peter J. Zimetbaum , Steven J. Kalbfleisch , Francis D. Murgatroyd , David A. Steckman , Lynda E. Rosenfeld , Ann C. Garlitski , Kyoko Soejima , Adarsh K. Bhan , Vasanth Vedantham , Timm M. Dickfeld , David B. De Lurgio , Pyotr G. Platonov , Matthew M. Zipse , Suguru Nishiuchi , Matthew L. Ortman , Calambur Narasimhan , Kris K. Patton , David G. Rosenthal , Siddharth S. Mukerji , Jarieke C. Hoogendoorn , Katja Zeppenfeld , William H. Sauer , Jordana Kron (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. (Journal of the American Heart Association)
12:29
Reliability of Past Medical History in a Single Hospital Participating in Get With The Guidelines?Stroke Registry - Christopher G. Favilla, Alice F. Ford , Ossama Khazaal , Daniel Cristancho , Emily Grodinsky , Judy Dawod , and Scott E. Kasner 1Department of Neurology University of Pennsylvania Philadelphia PA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe GWTG (Get With The Guidelines)?Stroke registry supports clinical research and quality improvement projects that often rely on past medical history elements, the reliability of which remains largely (...) (Journal of the American Heart Association)
12:29
Extended Anticoagulation After Pulmonary Embolism: A Multicenter Observational Cohort Analysis - Romain Chopard, Ida Ehlers Albertsen , Fiona Ecarnot , Sebastien Guth , Matthieu Besutti , Nicolas Falvo , Gregory Piazza , and Nicolas Meneveau 1Department of Cardiology University Hospital Jean Minjoz Besançon France 2EA3920 University of Burgundy Franche?Comté Besançon France 3F?CRIN INNOVTE Network Saint?Etienne France 4Aalborg Thrombosis Research Unit Aalborg University Hospital Aalborg Denmark 5Department of Internal Medicine University Hospital Dijon?Bourgogne Dijon France 6Division of Cardiovascular Medicine Department of Medicine Brigham and Women’s HospitalHarvard Medical School (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundPulmonary embolism (PE) has a long?term risk of adverse events, which can be prevented by extended anticoagulation. We compared clinical characteristics and outcomes between patients treated with 2?year (...) (Journal of the American Heart Association)
12:28
Increases in Circulating and Fecal Butyrate are Associated With Reduced Blood Pressure and Hypertension: Results From the SPIRIT Trial - Curtis Tilves, Hsin?Chieh Yeh , Nisa Maruthur , Stephen P. Juraschek , Edgar Miller , Karen White , Lawrence J. Appel , and Noel T. Mueller 1Department of Epidemiology Johns Hopkins University Bloomberg School of Public Health Baltimore MD 2Welch Center for Prevention, Epidemiology, and Clinical Research Johns Hopkins University Baltimore MD 3Division of General Medicine and Primary Care Beth Israel Deaconess Medical Center Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundShort chain fatty acids (SCFAs) are microbially derived end products of dietary fiber fermentation. The SCFA butyrate reduces blood pressure (BP) in mouse models. The association of SCFAs, including (...) (Journal of the American Heart Association)
12:28
Myocardial Injury in Patients With Acute and Subacute Chagas Disease in the Brazilian Amazon Using Cardiovascular Magnetic Resonance - Katia do Nascimento Couceiro, Jessica Vanina Ortiz , Mônica Regina Hosannah da Silva e Silva , Débora Raysa Teixeira de Sousa , Rubens Celso Andrade , Alba Regina Jorge Brandão , Rômulo Freire de Morais , Susan Smith Doria , Rafael Almeida Fonseca , Paula Rita Leite da Silva , Fabio Fernandes , Maria das Graças Vale Barbosa Guerra , Carlos Eduardo Rochitte , João Marcos Bemfica Barbosa Ferreira , and Jorge Augusto de Oliveira Guerra 1 Programa de Pós?Graduação em Medicina Tropical–Universidade do Estado do Amazonas Manaus Amazonas Brazil 2 Universidade Nilton Lins Manaus Amazonas Brazil 3 Instituto (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundChagas disease is a neglected tropical disease that is still considered a global health emergency. In the Amazon region, most of the reports are of acute cases that are associated with oral transmission. (...) (Journal of the American Heart Association)

20 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:02
From Purpose to Impact: Harnessing the Elements to Improve Peripheral Artery Disease Outcomes - Subhash Banerjee, Lawrence Hoang , and Douglas E. Drachman 1University of Texas Southwestern Medical Center Dallas TX 2Methodist Hospital Dallas TX 3Massachusetts General Hospital Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
12:02
Cardiovascular and Limb Events Following Endovascular Revascularization Among Patients ?65 Years Old: An American College of Cardiology PVI Registry Analysis - E. Hope Weissler, Yongfei Wang , Jordan M. Gales , Dmitriy N. Feldman , Shipra Arya , Eric A. Secemsky , Herbert D. Aronow , Beau M. Hawkins , J. Antonio Gutierrez , Manesh R. Patel , Jeptha P. Curtis , W. Schuyler Jones , and Rajesh V. Swaminathan 1Division of Vascular and Endovascular Surgery Department of Surgery Duke University School of Medicine Durham NC 2Section of Cardiovascular Medicine Department of Internal Medicine Yale School of Medicine New Haven CT 3Center of Outcome Research and Evaluation Yale?New Haven Health Services New Haven CT 4Texas Heart Institute Houston TX (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundWe aimed to characterize the occurrence of major adverse cardiovascular and limb events (MACE and MALE) among patients with peripheral artery disease (PAD) undergoing peripheral vascular intervention (PVI), (...) (Journal of the American Heart Association)
12:01
Moving Beyond Self?Reported Race in Our Understanding of Cardiovascular Medicine - Nancy Luo 1Sutter Heart and Vascular Institute Sacramento CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
12:01
A Frequentist Opting for the Road Less Traveled - Mirvat Alasnag, and Mamas A. Mamas 1Cardiac Center King Fahd Armed Forces Center Jeddah Saudi Arabia 2Keele Cardiovascular Research Group Keele University Stoke on Trent United Kingdom J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
12:01
When the Price Is Right: Beyond the Medical Risks and Benefits of Costly Therapies - Michelle M. Kittleson 1Department of Cardiology Smidt Heart InstituteCedars?Sinai Medical Center Los Angeles CA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
12:01
Impact of Financial Considerations on Willingness to Take Sacubitril/Valsartan for Heart Failure - Birju R. Rao, Candace D. Speight , Larry A. Allen , Scott D. Halpern , Yi?An Ko , Daniel D. Matlock , Miranda A. Moore , Alanna A. Morris , Laura D. Scherer , Mary C. Thomson , Peter Ubel , and Neal W. Dickert 1Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA 2Department of Medicine University of Colorado School of Medicine Aurora CO 3Palliative and Advanced Illness Research (PAIR) Center and Department of Medicine Pennsylvania Perelman School of Medicine Philadelphia PA 4Department of Biostatistics Emory University Rollins School of Public (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundSacubitril/valsartan improves health outcomes for heart failure with reduced ejection fraction relative to angiotensin?converting enzyme inhibitors or angiotensin receptor blockers, but it carries higher (...) (Journal of the American Heart Association)
12:00
Systematic Review and Network Meta?Analysis Comparing Bifurcation Techniques for Percutaneous Coronary Intervention - Dae Yong Park, Seokyung An , Neeraj Jolly , Steve Attanasio , Neha Yadav , Sunil Rao , and Aviral Vij 1Department of Medicine John H. Stroger Jr Hospital of Cook County Chicago IL 2Department of Biomedical Science Seoul National University Graduate School Seoul Korea 3Division of Cardiology Rush University Medical Center Chicago IL 4Division of Cardiology Cook County Health Chicago IL 5Division of Cardiology Rush Medical College Chicago IL 6Duke Clinical Research Institute and Duke University Health System Durham (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundBifurcation lesions account for 20% of all percutaneous coronary interventions and represent a complex subset which are associated with lower procedural success and higher rates of restenosis. The ideal (...) (Journal of the American Heart Association)
12:00
Angiotensin Receptor Neprilysin Inhibition and Associated Outcomes by Race and Ethnicity in Patients With Heart Failure With Reduced Ejection Fraction: Data From CHAMP?HF - Brittany Chapman, Anne S. Hellkamp , Laine E. Thomas , Nancy M. Albert , Javed Butler , J. Herbert Patterson , Adrian F. Hernandez , Fredonia B. Williams , Xian Shen , John A. Spertus , Gregg C. Fonarow , and Adam D. DeVore 1Department of Medicine Duke University School of Medicine Durham NC 2Duke Clinical Research Institute Durham NC 3Cleveland Clinic Cleveland OH 4University of Mississippi Medical Center Jackson MS 5Eshelman School of Pharmacy University of North Carolina Chapel Hill NC 6Mended Hearts Huntsville AL 7Novartis Pharmaceuticals Corporation East Hanover NJ 8Saint Luke’s Mid (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere are limited data on the use of angiotensin receptor neprilysin inhibitors (ARNIs) in minority populations with heart failure (HF) with reduced ejection fraction. We used data from the CHAMP?HF (Change (...) (Journal of the American Heart Association)

17 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:55
Invasive Versus Medical Management in Patients With Chronic Kidney Disease and Non–ST?Segment–Elevation Myocardial Infarction - Monil Majmundar, Gabriel Ibarra , Ashish Kumar , Rajkumar Doshi , Palak Shah , Roxana Mehran , Grant W. Reed , Rishi Puri , Samir R. Kapadia , Sripal Bangalore , and Ankur Kalra 1Department of Cardiology Maimonides Medical Center, Brooklyn New York NY 2Department of Internal Medicine Brown University Providence RI 3Department of Internal Medicine Cleveland Clinic Akron General Akron OH 4Division of Cardiology St. Joseph’s University Medical Center Paterson NJ 5Department of Internal Medicine New York Medical College/Metropolitan Hospital New York NY 6The Zena and Michael A. Wiener (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThe role of invasive management compared with medical management in patients with non–ST?segment–elevation myocardial infarction (NSTEMI) and advanced chronic kidney disease (CKD) is uncertain, given the (...) (Journal of the American Heart Association)
12:54
Invasive Management for Non–ST?Segment–Elevation Myocardial Infarction and Chronic Kidney Disease: Does One Size Fit All? - Ayman Elbadawi, Islam Y. Elgendy , and Paul Kumfa 1 Section of Cardiology Baylor College of Medicine Houston TX 2 Division of Cardiology University of Texas Southwestern Medical Center Dallas TX 3 Division of Cardiovascular Medicine Gill Heart Institute, University of Kentucky Lexington KY 4 Division of Cardiology University of Texas Medical Branch Galveston TX J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)

16 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

14:33
Trends, Predictors, and Outcomes of Cardiovascular Complications Associated With Polycystic Ovary Syndrome During Delivery Hospitalizations: A National Inpatient Sample Analysis (2002–2019) - Salman Zahid, Muhammad Zia Khan , Smitha Gowda , Nadeen N. Faza , Michael C. Honigberg , Arthur (Jason) Vaught , Carolyn Guan , Anum S. Minhas , and Erin D. Michos 1 Sands?Constellation Heart Institute Rochester General Hospital Rochester NY 2 Division of Cardiovascular Medicine West Virginia University Heart and Vascular Institute Morgantown WV 3 Division of Cardiology Houston Methodist DeBakey Heart and Vascular Center Houston TX 4 Cardiology Division, Department of Medicine Massachusetts General Hospital Boston MA 5 Division of Maternal Fetal Medicine, Department of Gynecology and (...) J Am Heart Assoc

Journal of the American Heart Association, Ahead of Print. BackgroundWomen with polycystic ovary syndrome (PCOS) have an increased risk of pregnancy?associated complications. However, data on peripartum cardiovascular complications remain limited. Hence, we investigated trends, outcomes, and (...) (Journal of the American Heart Association)

15 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:08
Association of Common and Rare Genetic Variation in the 3?Hydroxy?3?Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk - Jonas Ghouse, Gustav Ahlberg , Anne Guldhammer Skov , Henning Bundgaard , and Morten S. Olesen 1Laboratory for Molecular Cardiology Department of Cardiology Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark 2Laboratory for Molecular Cardiology Department of Biomedical Sciences University of Copenhagen Denmark 3Department of Ophthalmology Copenhagen University HospitalRigshospitalet?GlostrupUniversity of Copenhagen Denmark 4Department of Cardiology Copenhagen University Hospital, RigshospitaletUniversity of Copenhagen (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundResults from animal models and observational studies have raised concerns regarding the potential cataractogenic effects of statin treatment. We investigated whether common and rare genetic variants (...) (Journal of the American Heart Association)

14 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:42
Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out?of?Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry - Ryo Emoto, Mitsuaki Nishikimi , Muhammad Shoaib , Kei Hayashida , Kazuki Nishida , Kazuya Kikutani , Shinichiro Ohshimo , Shigeyuki Matsui , Nobuaki Shime , and Taku Iwami 1 Department of Biostatistics Nagoya University Graduate School of Medicine Nagoya Japan 2 Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan 3 Department of Emergency and Critical Care Medicine Nagoya University Graduate School of Medicine Nagoya Japan 4 Laboratory for Critical Care Physiology The Feinstein Institutes for Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundPredicting a spontaneous rhythm change from nonshockable to shockable before hospital arrival in patients with out?of?hospital cardiac arrest can help emergency medical services develop better strategies for (...) (Journal of the American Heart Association)
12:41
Association of Statins for Primary Prevention of Cardiovascular Diseases With Hospitalization for COVID?19: A Nationwide Matched Population?Based Cohort Study - Kim Bouillon, Bérangère Baricault , Laura Semenzato , Jérémie Botton , Marion Bertrand , Jérôme Drouin , Rosemary Dray?Spira , Alain Weill , and Mahmoud Zureik 1EPI?PHARE Scientific Interest Group in Epidemiology of Health Products Saint?Denis France 2Faculty of Pharmacy Paris?Saclay University Châtenay?Malabry France 3Paris?Saclay University UVSQ CESP?Inserm, Anti?infective evasion and pharmacoepidemiology Montigny le Bretonneux France J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere is little evidence on the relationship between statin use and the risk of hospitalization attributable to COVID?19.Methods and ResultsThe French National Healthcare Data System database was used to (...) (Journal of the American Heart Association)
12:41
Hypertension and Diabetes Status by Patterns of Stress in Older Adults From the US Health and Retirement Study: A Latent Class Analysis - Jessica R. Fernandez, Francisco A. Montiel Ishino , Faustine Williams , Natalie Slopen , and Allana T. Forde 1Division of Intramural Research National Institute on Minority Health and Health DisparitiesNational Institutes of Health Bethesda MD 2Department of Social and Behavioral Sciences Harvard University T. H. Chan School of Public Health Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundHypertension and diabetes disproportionately affect older non?Hispanic Black and Hispanic adults in the United States. Chronic stress may partially explain these disparities. This study identified underlying (...) (Journal of the American Heart Association)
12:40
Development and Validation of 3?Year Atrial Fibrillation Prediction Models Using Electronic Health Record With or Without Standardized Electrocardiogram Diagnosis and a Performance Comparison Among Models - Yunjin Yum, Seung Yong Shin , Hakje Yoo , Yong Hyun Kim , Eung Ju Kim , Gregory Y. H. Lip , and Hyung Joon Joo 1 Department of Biostatistics Korea University College of Medicine Seoul Republic of Korea 2 Cardiovascular and Arrhythmia Center Chung?Ang University Hospital Seoul Republic of Korea 3 Korea University Research Institute for Medical Bigdata Science Korea University Seoul Republic of Korea 4 Department of Internal Medicine Korea University Ansan Hospital Seoul Republic of Korea 5 Cardiovascular Center Korea University Guro Hospital Seoul Republic of Korea 6 Liverpool Center for (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundImproved prediction of atrial fibrillation (AF) may allow for earlier interventions for stroke prevention, as well as mortality and morbidity from other AF?related complications. We developed a clinically (...) (Journal of the American Heart Association)
12:38
Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes - Vivien Ngo, Bernd K. Fleischmann , Manfred Jung , Lutz Hein , and Achim Lother 1 Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine University of Freiburg Germany 2 Institute of Physiology I, Life & Brain Center, Medical Faculty University of Bonn Germany 3 Institute of Pharmaceutical Sciences University of Freiburg Germany 4 BIOSS Centre for Biological Signaling Studies University of Freiburg Germany 5 Interdisciplinary Medical Intensive Care (IMIT), Medical Center – University of Freiburg, Faculty of Medicine University of Freiburg (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundEpigenetic modulators have been proposed as promising new drug targets to treat adverse remodeling in heart failure. Here, we evaluated the potential of 4 epigenetic drugs, including the recently developed (...) (Journal of the American Heart Association)
12:38
Association of Race and Ethnicity on the Management of Acute Non?ST?Segment Elevation Myocardial Infarction - Tarryn Tertulien, Stephen T. Broughton , Gretchen Swabe , Utibe R. Essien , and Jared W. Magnani 1 Department of Medicine University of Pittsburgh Medical Center Pittsburgh Pennsylvania 2 Division of Cardiology UPMC Heart and Vascular Institute, University of Pittsburgh Pittsburgh Pennsylvania 3 Center for Health Equity Research and Promotion VA Pittsburgh Healthcare System Pittsburgh Pennsylvania J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundPrior studies have reported disparities by race in the management of acute myocardial infarction (MI), with many studies having limited covariates or now dated. We examined racial and ethnic differences in (...) (Journal of the American Heart Association)
12:38
Interaction Between Race, Ethnicity, Severe Mental Illness, and Cardiovascular Disease - Kevin O'Gallagher, James TH. Teo , Ajay M. Shah , and Fiona Gaughran 1 British Heart Foundation Centre of Research Excellence King’s College London London United Kingdom 2 King’s College Hospital NHS Foundation Trust London United Kingdom 3 Institute of Psychiatry, Psychology and Neuroscience King’s College London London United Kingdom 4 South London and Maudsley NHS Foundation Trust London United Kingdom J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. Severe mental illnesses, such as schizophrenia or bipolar disorder, affect ?1% of the population who, as a group, experience significant disadvantage in terms of physical health and reduced life expectancy. In this (...) (Journal of the American Heart Association)
12:37
Prognostic Value of Exercise Capacity in Kidney Transplant Candidates - Sean Tan, Yi Wen Thang , William R. Mulley , Kevan R. Polkinghorne , Satish Ramkumar , Kevin Cheng , Jasmine Chan , John Galligan , Mark Nolan , Adam J. Brown , Stuart Moir , James D. Cameron , Stephen J. Nicholls , Philip M. Mottram , and Nitesh Nerlekar 1 Monash Cardiovascular Research Centre, Victorian Heart Institute Monash University Melbourne Victoria Australia 2 Monash Heart Monash Health Melbourne Victoria Australia 3 Department of Nephrology Monash Health Melbourne Victoria Australia 4 Department of Medicine Monash University Melbourne Victoria Australia 5 Baker Heart and (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundExercise stress testing for cardiovascular assessment in kidney transplant candidates has been shown to be a feasible alternative to pharmacologic methods. Exercise stress testing allows the additional (...) (Journal of the American Heart Association)
12:37
Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial Cells - Michael Hauke, Robert Eckenstaler , Anne Ripperger , Anna Ender , Heike Braun , and Ralf A. Benndorf 1Department of Clinical Pharmacy and Pharmacotherapy Institute of PharmacyMartin?Luther?University Halle?Wittenberg Halle (Saale) Germany J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThe small GTPase RhoA (Ras homolog gene family, member A) regulates a variety of cellular processes, including cell motility, proliferation, survival, and permeability. In addition, there are reports (...) (Journal of the American Heart Association)
12:37
Effects of Clinical Trial or Research Program Participation Status on In?Hospital Mortality After Transcatheter Aortic Valve Implantation - Tadao Aikawa, Toshiki Kuno , Jef Van den Eynde , Alexandros Briasoulis , and Aaqib H. Malik 1 Department of Cardiology Hokkaido Cardiovascular Hospital Sapporo Japan 2 Department of Radiology Jichi Medical University Saitama Medical Center Saitama Japan 3 Division of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine New York NY 4 Helen B. Taussig Heart Center The Johns Hopkins Hospital and School of Medicine Baltimore MD 5 Department of Cardiovascular Sciences KU Leuven Leuven Belgium 6 Section of Heart Failure and Transplantation, Division of Cardiovascular (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
12:37
Moderate? and High?Intensity Exercise Improves Lipoprotein Profile and Cholesterol Efflux Capacity in Healthy Young Men - Kelly M. Stanton, Vivian Kienzle , Donna Lee M. Dinnes , Irina Kotchetkov , Wendy Jessup , Leonard Kritharides , David S. Celermajer , and Kerry?Anne Rye 1Heart Research Institute Sydney New South Wales Australia 2The University of Sydney New South Wales Australia 3Royal Brisbane and Women’s Hospital Herston Queensland Australia 4The ANZAC Research Institute Concord New South Wales Australia 5Royal Prince Alfred Hospital Sydney New South Wales Australia 6The University of New South Wales Sydney New South Wales (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundExercise is associated with a reduced risk of cardiovascular disease. Increased high?density lipoprotein cholesterol (HDL?C) levels are thought to contribute to these benefits, but much of the research in (...) (Journal of the American Heart Association)
12:36
Integrating a Polygenic Risk Score for Coronary Artery Disease as a Risk?Enhancing Factor in the Pooled Cohort Equation: A Cost?Effectiveness Analysis Study - Deo Mujwara, Geoffrey Henno , Stephen T. Vernon , Siyang Peng , Paolo Di Domenico , Brock Schroeder , George B. Busby , Gemma A Figtree , and Giordano Bottà 1Allelica, Inc Wilmington DE 2 Illumina, Inc San Diego CA 3Kolling InstituteRoyal North Shore Hospital Sydney NSW Australia 4Charles Perkins CentreUniversity of Sydney NSW Australia 5Department of Cardiology Royal North Shore Hospital Sydney NSW Australia J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCardiovascular diseases are the leading cause of death in the United States, yet a significant proportion of adults at high risk remain undetected by standard screening practices. Polygenic risk score for (...) (Journal of the American Heart Association)
12:36
Sex?Specific Differences in Clinical Outcomes After Percutaneous Coronary Intervention: Insights from the TAILOR?PCI Trial - Mina Madan, J. Dawn Abbott , Ryan Lennon , Derek Y. F. So , Andrea M. MacDougall , Mary Ann McLaughlin , Vishakantha Murthy , Jacqueline Saw , Charanjit Rihal , Michael E. Farkouh , Naveen L. Pereira , Shaun G. Goodman 1Schulich Heart CentreSunnybrook Health Sciences CentreUniversity of Toronto Toronto Ontario Canada 2Division of Cardiology Lifespan Cardiovascular Institute Warren Alpert Medical School of Brown University Providence RI 3Department of Quantitative Health Sciences Mayo Clinic Rochester MN 4University of Ottawa Heart Institute Ottawa Ontario Canada 5Thunder Bay Regional (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundTAILOR?PCI (Tailored Antiplatelet Initiation to Lessen Outcomes due to decreased Clopidogrel Response After Percutaneous Coronary Intervention) studied genotype?guided selection of antiplatelet therapy after (...) (Journal of the American Heart Association)
12:35
Sex?Based Differences in Outcomes Following Peripheral Artery Revascularization: Insights From VOYAGER PAD - Connie N. Hess, Iris Baumgartner , Sonia S. Anand , Mark R. Nehler , Manesh R. Patel , E. Sebastian Debus , Michael Szarek , Warren Capell , Eva Muehlhofer , Scott D. Berkowitz , Lloyd P. Haskell , Rupert M. Bauersachs , Marc P. Bonaca , and Judith Hsia 1 Division of Cardiology, Department of Medicine University of Colorado School of Medicine Aurora CO 2 CPC Clinical Research Aurora CO 3 Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital University of Bern Switzerland 4 Population Health Research Institute, Hamilton Health Sciences McMaster (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundDespite high female prevalence of peripheral artery disease (PAD), little is known about sex?based outcomes after lower extremity revascularization (LER) for symptomatic PAD. The effects of rivaroxaban (...) (Journal of the American Heart Association)
12:35
Characterization of “ICU?30”: A Binary Composite Outcome for Neonates With Critical Congenital Heart Disease - Monique M. Gardner, Garrett Keim , Jill Hsia , Anh D. Mai , J. William Gaynor , Andrew C. Glatz , and Nadir Yehya 1Division of Cardiac Critical Care Department of Anesthesiology and Critical Care The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of Pennsylvania Philadelphia PA 2Division of Critical Care Department of Anesthesiology and Critical Care The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of Pennsylvania Philadelphia PA 3Division of Cardiology Department of Pediatrics The Children’s Hospital of Philadelphia (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundNeonates with heart disease requiring cardiopulmonary bypass surgery are at high risk for mortality and morbidity. As it is rare, short?term mortality is difficult to use as a primary outcome for clinical (...) (Journal of the American Heart Association)
12:34
Aortic Dimensions Are Larger in Patients With Fibromuscular Dysplasia - Arielle M. Schwartz, Esther Kim , Patrick Gleason , Xiaona Li , Yi?An Ko , and Bryan J Wells 1 Willis Hurst Internal Medicine Residency Program Emory University Atlanta GA 2 Division of Cardiovascular Medicine, Department of Medicine Vanderbilt University Medical Center Nashville NC 3 Division of Cardiology, Department of Medicine Emory University School of Medicine Atlanta GA 4 Department of Biostatistics and Bioinformatics, Rollins School of Public Health Emory University Atlanta (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundFibromuscular dysplasia (FMD) is a disease of unknown etiology that causes stenosis, aneurysmal dilatation, and dissection of vascular beds. Known to affect medium?sized arteries, FMD is not typically (...) (Journal of the American Heart Association)
12:34
Protective Effects of MicroRNA?200b?3p Encapsulated by Mesenchymal Stem Cells–Secreted Extracellular Vesicles in Myocardial Infarction Via Regulating BCL2L11 - Jun Wan, Shaoyan Lin , Zhuo Yu , Zhengkun Song , Xuefeng Lin , Rongning Xu , and Songlin Du 1Department of Cardiovascular Surgery Nanfang Hospital Southern Medical University Guangzhou Guangdong China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundExtracellular vesicles (EVs) are a popular treatment candidate for myocardial injury. This work investigated the effects of mesenchymal stem cells (MSCs)–secreted EVs–derived miR?200b?3p on cardiomyocyte (...) (Journal of the American Heart Association)
12:34
Systematic Review of Cerebral Phenotypes Associated With Monogenic Cerebral Small?Vessel Disease - Ed Whittaker, Sophie Thrippleton , Liza Y. W. Chong , Victoria G. Collins , Amy C. Ferguson , David E. Henshall , Emily Lancastle , Tim Wilkinson , Blair Wilson , Kirsty Wilson , Cathie Sudlow , Joanna Wardlaw , and Kristiina Rannikmäe 1Medical School University of Edinburgh Edinburgh United Kingdom 2Centre for Medical Informatics Usher Institute University of Edinburgh Edinburgh United Kingdom 3Centre for Clinical Brain Sciences University of Edinburgh Edinburgh United Kingdom 4NHS Greater Glasgow and Clyde Glasgow United Kingdom 5NHS Lothian Edinburgh United Kingdom 6BHF Data Science (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCerebral small?vessel disease (cSVD) is an important cause of stroke and vascular dementia. Most cases are multifactorial, but an emerging minority have a monogenic cause. WhileNOTCH3is the best?known gene, (...) (Journal of the American Heart Association)
12:34
Relative Contribution of Blood Pressure in Childhood, Young? and Mid?Adulthood to Large Artery Stiffness in Mid?Adulthood - Yaxing Meng, Marie?Jeanne Buscot , Markus Juonala , Feitong Wu , Matthew K. Armstrong , Brooklyn J. Fraser , Katja Pahkala , Nina Hutri?Kähönen , Mika Kähönen , Tomi Laitinen , Jorma S. A. Viikari , Olli T. Raitakari , Costan G. Magnussen , and James E. Sharman 1Menzies Institute for Medical ResearchUniversity of Tasmania Hobart Australia 2Department of Medicine University of Turku Turku Finland 3Division of Medicine Turku University Hospital Turku Finland 4Research Centre of Applied and Preventive Cardiovascular Medicine University of Turku Turku Finland 5Centre for Population Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundBlood pressure associates with arterial stiffness, but the contribution of blood pressure at different life stages is unclear. We examined the relative contribution of childhood, young? and mid?adulthood (...) (Journal of the American Heart Association)
12:33
Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart Study - Vibhu Parcha, Marguerite R. Irvin , Leslie A. Lange , Nicole D. Armstrong , Akhil Pampana , Mariah Meyer , Suzanne E. Judd , Garima Arora , and Pankaj Arora 1Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL 2Department of Epidemiology University of Alabama at Birmingham Birmingham AL 3Division of Biomedical Informatics and Personalized Medicine Department of Medicine University of Colorado School of Medicine Aurora CO 4Department of Epidemiology University of Colorado School of Public Health Aurora CO 5Department of Biostatistics University of Alabama (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCorin enzyme contributes to the processing of inactive natriuretic peptides to bioactive hormones. In Black individuals, Corin gene variants (rs111253292 [Q568P] and rs75770792 [T555I]) have been previously (...) (Journal of the American Heart Association)
12:33
Transcatheter Aortic Valve Implantation With and Without Resheathing and Repositioning: A Systematic Review and Meta?analysis - Francesco Moroni, Lorenzo Azzalini , Lars Sondergaard , Guilherme F. Attizzani , Santiago García , Hani Jneid , Mamas A. Mamas , and Rodrigo Bagur 1Division of Cardiology Pauley Heart CenterVirginia Commonwealth University Richmond VA 2Division of Cardiology Department of Medicine University of Washington Seattle WA 3The Heart Centre, RigshospitaletCopenhagen University Hospital Copenhagen Denmark 4Harrington Heart and Vascular InstituteUniversity Hospitals Cleveland Medical Center Cleveland OH 5The Carl and Edyth Lindner Center for Research and Education, The Christ Hospital Cincinnati OH (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere is a concern that resheathing/repositioning of transcatheter heart valves during transcatheter aortic valve implantation (TAVI) may lead to an increased risk of periprocedural complications. We aimed (...) (Journal of the American Heart Association)
12:33
Altered Cerebral Microstructure in Adults With Atrial Septal Defect and Ventricular Septal Defect Repaired in Childhood - Benjamin Asschenfeldt, Lars Evald , Camilla Salvig , Johan Heiberg , Leif Østergaard , Simon Fristed Eskildsen , and Vibeke Elisabeth Hjortdal 1Department of Cardiothoracic & Vascular Surgery Aarhus University Hospital Denmark 2Center of Functionally Integrative Neuroscience Aarhus University Denmark 3Department of Clinical Medicine Aarhus University Denmark 4Hammel Neurorehabilitation Centre and University Research Clinic Denmark 5Neuroradiology Research Unit, Department of Radiology Aarhus University Hospital Denmark 6Department of Cardiothoracic Surgery, Rigshospitalet and Institute of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundDelayed brain development, brain injury, and neurodevelopmental disabilities are commonly observed in infants operated for complex congenital heart defect. Our previous findings of poorer neurodevelopmental (...) (Journal of the American Heart Association)
12:33
Low?Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific - Arjen J. Cupido, Folkert W. Asselbergs , A. Floriaan Schmidt , and G. Kees Hovingh 1Department of Vascular Medicine Amsterdam University Medical Centerslocation AMCUniversity of Amsterdam Netherlands 2Department of Cardiology Division of Heart & Lungs University Medical Center UtrechtUtrecht University Utrecht the Netherlands 3Division of Cardiology Department of Medicine University of California, Los Angeles Los Angeles CA 4Faculty of Population Health Sciences Institute of Cardiovascular ScienceUniversity College London London United Kingdom 5Health Data Research UK and Institute of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundEpidemiological studies show that women are generally at lower risk for cardiovascular disease than men. Here, we investigated the sex?specific differential effect of genetically increased low?density (...) (Journal of the American Heart Association)
12:32
Evaluation of a Population?Wide Mobile Health Physical Activity Program in 696 907 Adults in Singapore - Jiali Yao, Nicole Lim , Jeremy Tan , Andre Matthias Müller , Rob Martinus van Dam , Cynthia Chen , Chuen Seng Tan , and Falk Müller?Riemenschneider 1Saw Swee Hock School of Public Health National University of Singapore Singapore 2Policy, Research and Surveillance Division Health Promotion Board Singapore 3Berlin Institute of HealthCharite University Medical Centre Berlin Germany J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundEvidence of scaled?up physical activity interventions is scarce. This study evaluates the uptake, engagement, and effectiveness of one such intervention program.Methods and ResultsThe program was open to (...) (Journal of the American Heart Association)
12:32
Radiofrequency Catheter Ablation for Pediatric Atrioventricular Nodal Reentrant Tachycardia: Impact of Age on Procedural Methods and Durable Success - Edward T. O’Leary, Jamie Harris , Kimberlee Gauvreau , Courtney Gentry , Audrey Dionne , Dominic J. Abrams , Mark E. Alexander , Vassilios J. Bezzerides , Elizabeth S. DeWitt , John K. Triedman , Edward P. Walsh , and Douglas Y. Mah 1Department of Cardiology Boston Children’s Hospital Boston MA 2Harvard Medical School Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCatheter?based slow?pathway modification (SPM) is the treatment of choice for symptomatic atrioventricular nodal reentrant tachycardia (AVNRT). We sought to investigate the interactions between patient age (...) (Journal of the American Heart Association)
12:32
Association of Familial History of Diabetes, Hypertension, Dyslipidemia, Stroke, or Myocardial Infarction With Risk of Kawasaki Disease - Ji Hee Kwak, Eun Kyo Ha , Ju Hee Kim , Hye Ryung Cha , Seung Won Lee , and Man Yong Han 1Department of Pediatrics Kangbuk Samsung HospitalSungkyunkwan University School of Medicine Seoul Korea 2Department of Pediatrics Kangnam Sacred Heart HospitalHallym University College of Medicine Seoul Korea 3Department of Pediatrics Kangdong Sacred Heart HospitalHallym University College of Medicine Seoul Korea 4Department of Data Science Sejong University College of Software Convergence Seoul Korea 5Department of Precision Medicine Sungkyunkwan University School of Medicine Suwon Korea 6Department (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere are few studies on the association with Kawasaki disease in children and the family’s history of cardiovascular disease (CVD). The aim of this study was to identify the association of increased risks (...) (Journal of the American Heart Association)
12:32
Correlation Between Cardiac Images, Biomarkers, and Amyloid Load in Wild?Type Transthyretin Amyloid Cardiomyopathy - Mami Morioka, Seiji Takashio , Naoya Nakashima , Masato Nishi , Akira Fujiyama , Kyoko Hirakawa , Shinsuke Hanatani , Hiroki Usuku , Eiichiro Yamamoto , Masafumi Kidoh , Seitaro Oda , Kenichi Matsushita , Mitsuharu Ueda , and Kenichi Tsujita 1Departments of Cardiovascular Medicine Graduate School of Medical Sciences Kumamoto University Kumamoto Japan 2Departments of Diagnostic Radiology Graduate School of Medical Sciences Kumamoto University Kumamoto Japan 3Departments of Neurology Graduate School of Medical Sciences Kumamoto University Kumamoto (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundSeveral imaging parameters and biomarkers provide diagnostic and prognostic information for wild?type transthyretin amyloid cardiomyopathy. However, the relevance of these parameters and their association (...) (Journal of the American Heart Association)

8 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:52
Underdiagnosis and Undertreatment of Modifiable Cardiovascular Risk Factors Among Survivors of Childhood Cancer - Eric J. Chow, Yan Chen , Gregory T. Armstrong , Laura?Mae Baldwin , Casey R. Cai , Todd M. Gibson , Melissa M. Hudson , Aaron McDonald , Paul C. Nathan , Jeffrey E. Olgin , Karen L. Syrjala , Emily S. Tonorezos , Kevin C. Oeffinger , and Yutaka Yasui 1Public Health Sciences and Clinical Research Divisions Fred Hutchinson Cancer Research Center Seattle WA 2Department of Pediatrics Seattle Children’s HospitalUniversity of Washington Seattle WA 3University of Alberta Edmonton Alberta Canada 4Department of Epidemiology and Cancer Control St. Jude Children’s Research Hospital Memphis TN (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundDetermine the prevalence and predictors associated with underdiagnosis and undertreatment of modifiable cardiovascular disease (CVD) risk factors (hypertension, dyslipidemia, glucose intolerance/diabetes) (...) (Journal of the American Heart Association)

6 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:04
Impact of the Obesity Paradox Between Sexes on In?Hospital Mortality in Cardiogenic Shock: A Retrospective Cohort Study - Woochan Kwon, Seung Hun Lee , Jeong Hoon Yang , Ki Hong Choi , Taek Kyu Park , Joo Myung Lee , Young Bin Song , Joo?Yong Hahn , Seung?Hyuk Choi , Chul?Min Ahn , Young?Guk Ko , Cheol Woong Yu , Woo Jin Jang , Hyun?Joong Kim , Sung Uk Kwon , Jin?Ok Jeong , Sang?Don Park , Sungsoo Cho , Jang?Whan Bae , and Hyeon?Cheol Gwon 1Division of Cardiology Department of Medicine Heart Vascular Stroke InstituteSamsung Medical CenterSungkyunkwan University School of Medicine Seoul Republic of Korea 2Division of Cardiology Department of Internal Medicine Chonnam National University Hospital Gwangju (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundSeveral studies have shown that obesity is associated with better outcomes in patients with cardiogenic shock (CS). Although this phenomenon, the “obesity paradox,” reportedly manifests differently based on (...) (Journal of the American Heart Association)
12:03
Is There an Obesity Paradox in Cardiogenic Shock? - Carl J. Lavie, Adrian daSilva?deAbreu , Hector O. Ventura , and Mandeep R. Mehra 1John Ochsner Heart and Vascular InstituteOchsner Clinical School ? The University of Queensland School of Medicine New Orleans LA 2Section of Cardiovascular Medicine Yale School of MedicineHeart and Vascular CenterYale?New Haven Hospital New Haven CT 3Brigham and Women’s Hospital and Harvard Medical School Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
12:02
Cardiac Magnetic Resonance Imaging–Based Screening for Cardiac Sarcoidosis in Patients With Atrioventricular Block Requiring Temporary Pacing - Aino?Maija Vuorinen, Jukka Lehtonen , Sami Pakarinen , Miia Holmström , Sari Kivistö , and Touko Kaasalainen 1Radiology HUS Diagnostic CenterUniversity of Helsinki and Helsinki University Hospital Helsinki Finland 2Heart and Lung Center University of Helsinki and Helsinki University Hospital Helsinki Finland 3Haartman HospitalUniversity of Helsinki and Helsinki University Hospital Helsinki Finland J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundSome myocardial diseases, such as cardiac sarcoidosis, predispose to complete atrioventricular block. The European Society of Cardiology Guidelines on cardiac pacing in 2021 recommend myocardial disease (...) (Journal of the American Heart Association)
12:02
Managing Patients With Advanced Atrioventricular Block: The Essential Role of Cardiovascular Magnetic Resonance Imaging for Timely and Accurate Diagnosis - Lisa von Wald, and Chetan Shenoy 1Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
12:01
Idiopathic Recurrent Pericarditis: Not Really So Idiopathic? - François Roubille, Clément Delmas , and Camille Roubille 1Cardiology Department INI?CRT PhyMedExp INSERM CNRS CHU de MontpellierUniversité de Montpellier France 2Intensive Cardiac Care Unit Rangueil University Hospital/Institute of Metabolic and Cardiovascular Diseases UMR?1048 National Institute of Health and Medical Research Toulouse France 3Department of Internal Medicine PhyMedExp CHU MontpellierMontpellier University Montpellier France J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
12:01
Pericarditis and Autoinflammation: A Clinical and Genetic Analysis of Patients With Idiopathic Recurrent Pericarditis and Monogenic Autoinflammatory Diseases at a National Referral Center - Claire J. Peet, Dorota Rowczenio , Ebun Omoyinmi , Charalampia Papadopoulou , Bella Ruth R. Mapalo , Michael R. Wood , Francesca Capon , and Helen J. Lachmann 1National Amyloidosis Centre Royal Free London NHS Foundation Trust & Division of Medicine University, College London London United Kingdom 2Department of Medical and Molecular Genetics King’s College London London United Kingdom J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundIdiopathic recurrent pericarditis (IRP) is an orphan disease that carries significant morbidity, partly driven by corticosteroid dependence. Innate immune modulators, colchicine and anti?interleukin?1 agents, (...) (Journal of the American Heart Association)
12:00
Arrhythmogenesis and Prolonged Repolarization From Synthetic Opioids: Finally Sorted? - Lee L. Eckhardt 1Department of Medicine University of Wisconsin?Madison Madison WI J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
11:59
Methadone Blockade of Cardiac Inward Rectifier K+ Current Augments Membrane Instability and Amplifies U Waves on Surface ECGs: A Translational Study - Michael G. Klein, Mori J. Krantz , Naheed Fatima , Ashlie Watters , Dayan Colon?Sanchez , Robert M. Geiger , Robert E. Goldstein , Soroosh Solhjoo , Philip S. Mehler , Thomas P. Flagg , and Mark C. Haigney 1Cardiology Division Department of Medicine Uniformed Services University Bethesda MD 2Department of Anatomy, Physiology & Genetics Uniformed Services University Bethesda MD 3Psychiatry Division Outpatient Behavioral Health Services, Denver Health, & University of Colorado School of Medicine Denver CO 4Denver Health Medical Center Cardiology Division Denver CO 5ACUTE at Denver Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundMethadone is associated with a disproportionate risk of sudden death and ventricular tachyarrhythmia despite only modest inhibition of delayed rectifier K+current (IKr),the principal mechanism of (...) (Journal of the American Heart Association)

3 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

12:39
Workers’ Activity Profiles Associated With Predicted 10?Year Cardiovascular Disease Risk - Aviroop Biswas, Cynthia Chen , Stephanie A. Prince , Peter M. Smith , and Cameron A. Mustard 1Institute for Work & Health Toronto Ontario Canada 2Dalla Lana School of Public Health University of Toronto Ontario Canada 3Centre for Surveillance and Applied Research Public Health Agency of CanadaOttawa Ontario Canada 4School of Epidemiology and Public Health Faculty of Medicine University of Ottawa Ontario Canada 5Department of Epidemiology and Preventive Medicine Monash University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 14, July 19, 2022. BackgroundThere is a need to explore common activity patterns undertaken by workers and the association between these activity profiles and cardiovascular disease (CVD). This study explored the number and type of (...) (Journal of the American Heart Association)
12:41
Circulating S?Glutathionylated cMyBP?C as a Biomarker for Cardiac Diastolic Dysfunction - Xiaoxu Zhou, Euy?Myoung Jeong , Hong Liu , Bahaa Kaseer , Man Liu , Suvash Shrestha , Hafiz Imran , Kylie Kavanagh , Ning Jiang , Lori?Ann Desimone , Feng Feng , Guangbin Shi , Go Eun Jeong , Anyu Zhou , Philip Stockwell , and Samuel C. Dudley 1Division of Cardiology Department of Medicine The Lillehei Heart InstituteUniversity of Minnesota Minneapolis MN 2Lifespan Cardiovascular Research Center Brown University Providence RI 3Department of Pathology Wake Forest Baptist Medical Center Winston?Salem NC 4Department of Biology and Medicine Brown University Providence (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundcMyBP?C (Cardiac myosin binding protein?C) regulates cardiac contraction and relaxation. Previously, we demonstrated that elevated myocardial S?glutathionylation of cMyBP?C correlates with diastolic dysfunction (...) (Journal of the American Heart Association)
12:40
Relationship Between Risk of Atherosclerotic Cardiovascular Disease, Inflammation, and Coronary Microvascular Dysfunction in Rheumatoid Arthritis - Brittany Weber, Dana Weisenfeld , Thany Seyok , Sicong Huang , Elena Massarotti , Leanne Barrett , Courtney Bibbo , Daniel H. Solomon , Jorge Plutzky , Marcy Bolster , Marcelo Di Carli , and Katherine P. Liao 1Heart and Vascular Center Division of Cardiovascular Medicine Department of Medicine Brigham and Women’s HospitalHarvard Medical School Boston MA 2Division of Rheumatology, Inflammation, and Immunity Brigham and Women’s Hospital Harvard Medical School Boston MA 3Division of Rheumatology, Allergy and Immunology Massachusetts General HospitalHarvard Medical School Boston MA (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
12:40
Prognostic Implications of Prestent Pullback Pressure Gradient and Poststent Quantitative Flow Ratio in Patients Undergoing Percutaneous Coronary Intervention - Neng Dai, Sheng Yuan , Kefei Dou , Rui Zhang , Nan Hu , Jining He , Changdong Guan , Tongqiang Zou , Zheng Qiao , Shaofeng Duan , Lihua Xie , Yongfu Yu , Yingmei Zhang , Bo Xu , and Junbo Ge 1Department of Cardiology Zhongshan HospitalFudan UniversityShanghai Institute of Cardiovascular Diseases Shanghai China 2National Clinical Research Center for Interventional Medicine Shanghai China 3State Key Laboratory of Cardiovascular Disease Beijing China 4Cardiometabolic Medicine Center Fu Wai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundCoronary diffuse disease associates with poor outcomes, but little is known about its role after percutaneous coronary intervention (PCI). We aimed to investigate the prognostic implication of pre?PCI focal (...) (Journal of the American Heart Association)
12:40
Predictors of Recurrent Stroke After Embolic Stroke of Undetermined Source in the RE?SPECT ESUS Trial - Victor J. Del Brutto, Han?Christoph Diener , J. Donald Easton , Christopher B. Granger , Lisa Cronin , Eva Kleine , Claudia Grauer , Martina Brueckmann , Kazunori Toyoda , Peter D. Schellinger , Philippe Lyrer , Carlos A. Molina , Aurauma Chutinet , Christopher F. Bladin , Conrado J. Estol , and Ralph L. Sacco 1Department of Neurology University of Miami Miller School of Medicine Miami FL 2Department of Neurology University Duisburg?Essen Essen Germany 3Department of Neurology University of California San Francisco CA 4Duke Clinical Research Institute Durham NC 5Boehringer Ingelheim (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundWe sought to determine recurrent stroke predictors among patients with embolic strokes of undetermined source (ESUS).Methods and ResultsWe applied Cox proportional hazards models to identify clinical (...) (Journal of the American Heart Association)
12:40
Machine Learning–Based Risk Model for Predicting Early Mortality After Surgery for Infective Endocarditis - Li Luo, Sui?qing Huang , Chuang Liu , Quan Liu , Shuohui Dong , Yuan Yue , Kai?zheng Liu , Lin Huang , Shun?jun Wang , Hua?yang Li , Shaoyi Zheng , and Zhong?kai Wu 1Department of Cardiac Surgery The First Affiliated Hospital of Sun Yat?sen University Guangzhou P. R. China 2School of Computer Science and Technology Xidian University Xi’an P. R. China 3Department of General Surgery Qianfoshan HospitalShandong University Jinan P. R. China 4Department of Cardiovascular Surgery Nanfang HospitalSouthern Medical University Guangzhou P. R. (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe early mortality after surgery for infective endocarditis is high. Although risk models help identify patients at high risk, most current scoring systems are inaccurate or inconvenient. The objective of (...) (Journal of the American Heart Association)
12:40
p53?Dependent Mitochondrial Compensation in Heart Failure With Preserved Ejection Fraction - Xiaonan Chen, Hao Lin , Weiyao Xiong , Jianan Pan , Shuying Huang , Shan Xu , Shufang He , Ming Lei , Alex Chia Yu Chang , and Huili Zhang 1Department of Cardiology Ninth People’s HospitalShanghai Jiao Tong University School of Medicine Shanghai China 2Shanghai Institute of Precision MedicineNinth People’s HospitalShanghai Jiao Tong University School of Medicine Shanghai China J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundHeart failure with preserved ejection fraction (HFpEF) accounts for 50% of patients with heart failure. Clinically, HFpEF prevalence shows age and gender biases. Although the majority of patients with HFpEF (...) (Journal of the American Heart Association)
12:39
Cost?Effectiveness of Cilostazol Added to Aspirin or Clopidogrel for Secondary Prevention After Noncardioembolic Stroke - Lily W. Zhou, Lironn Kraler , Adam de Havenon , and Maarten G. Lansberg 1Stanford Stroke Center Stanford University Palo Alto CA 2Division of Neurology and Vancouver Stroke Program University of British Columbia Vancouver British Columbia Canada 3Department of Neurology Yale University New Haven CT J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe objective of the study was to assess the cost?effectiveness of cilostazol (a selective phosphodiesterase 3 inhibitor) added to aspirin or clopidogrel for secondary stroke prevention in patients with (...) (Journal of the American Heart Association)
12:39
Amiodarone Use and All?Cause Mortality in Patients With a Continuous?Flow Left Ventricular Assist Device - Rakesh Gopinathannair, Naga Venkata K. Pothineni , Jaimin R. Trivedi , Henri Roukoz , Jennifer Cowger , Mustafa M. Ahmed , Adarsh Bhan , Ashwin K. Ravichandran , Geetha Bhat , Amin Al Ahmad , Andrea Natale , Luigi Di Biase , Mark S. Slaughter , and Dhanunjaya Lakkireddy 1Kansas City Heart Rhythm Institute Overland Park KS 2Department of Cardiothoracic Surgery University of Louisville Louisville KY 3Division of Cardiology University of Minnesota Minneapolis MN 4Division of Cardiology Henry Ford Hospital Detroit MI 5Division of Cardiology University of Florida Gainesville FL 6Division of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundAtrial and ventricular arrhythmias are commonly encountered in patients with advanced heart failure, with amiodarone being the most commonly used antiarrhythmic drug in continuous?flow left ventricular assist (...) (Journal of the American Heart Association)
12:39
Clinician Responses to a Clinical Decision Support Advisory for High Risk of Torsades de Pointes - Tyler Gallo, C. William Heise , Raymond L. Woosley , James E. Tisdale , Malinda S. Tan , Sheila M. Gephart , Corneliu C. Antonescu , and Daniel C. Malone 1Division of Clinical Data Analytics and Decision Support University of Arizona College of Medicine–Phoenix AZ 2Department of Pharmacy Practice and Science University of Arizona College of Pharmacy Phoenix AZ 3Department of Medical Toxicology Banner–University Medical Center Phoenix Phoenix AZ 4Arizona Center for Education and Research on Therapeutics Oro Valley AZ 5Department of Pharmacy Practice College of Pharmacy Purdue University (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundTorsade de pointes (TdP) is a potentially fatal cardiac arrhythmia that is often drug induced. Clinical decision support (CDS) may help minimize TdP risk by guiding decision making in patients at risk. CDS (...) (Journal of the American Heart Association)
12:39
Pyruvate Kinase M2 Protects Heart from Pressure Overload?Induced Heart Failure by Phosphorylating RAC1 - Le Ni, Bowen Lin , Lingjie Hu , Ruoyu Zhang , Fengmei Fu , Meiting Shen , Jian Yang , and Dan Shi 1Department of Cardiology Shanghai East HospitalTongji University School of Medicine Shanghai China 2Key Laboratory of Arrhythmias of the Ministry of Education of China Shanghai East HospitalTongji University School of Medicine Shanghai China 3Department of Cell Biology Tongji University School of Medicine Shanghai China 4Jinzhou Medical University Liaoning China 5Institute of Medical Genetics Tongji University Shanghai (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundHeart failure, caused by sustained pressure overload, remains a major public health problem. PKM (pyruvate kinase M) acts as a rate?limiting enzyme of glycolysis. PKM2 (pyruvate kinase M2), an alternative (...) (Journal of the American Heart Association)
12:38
Association Between Systolic Blood Pressure Variability and Major Adverse Cardiovascular Events in Korean Patients With Chronic Kidney Disease: Findings From KNOW?CKD - Cheol Ho Park, Hyung Woo Kim , Young Su Joo , Jung Tak Park , Tae Ik Chang , Tae?Hyun Yoo , Sue Kyung Park , Dong?Wan Chae , Wookyung Chung , Yong?Soo Kim , Kook?Hwan Oh , Shin?Wook Kang , Seung Hyeok Han , and 1Department of Internal Medicine College of MedicineInstitute of Kidney Disease ResearchYonsei University Seoul Republic of Korea 2Department of Internal Medicine National Health Insurance Service Medical CenterIlsan Hospital Goyangshi Republic of Korea 3Department of Preventive Medicine Seoul National University College of Medicine Seoul Republic of Korea 4Department of Internal (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundWhether visit?to?visit systolic blood pressure (SBP) variability can predict major adverse cardiovascular events (MACE) in patients with chronic kidney disease is unclear.Methods and ResultsWe investigated the (...) (Journal of the American Heart Association)
12:38
Subcutaneous Versus Transvenous Implantable Defibrillator Therapy: A Systematic Review and Meta?Analysis of Randomized Trials and Propensity Score–Matched Studies - Khi Yung Fong, Colin Jun Rong Ng , Yue Wang , Colin Yeo , and Vern Hsen Tan 1Yong Loo Lin School of MedicineNational University of Singapore Singapore 2Department of Cardiology Changi General Hospital Singapore J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundSubcutaneous implantable cardioverter?defibrillators (S?ICDs) have been of great interest as an alternative to transvenous implantable cardioverter?defibrillators (TV?ICDs). No meta?analyses synthesizing data (...) (Journal of the American Heart Association)
12:38
Risk Burden of Coronary Perforation in Chronic Total Occlusion Recanalization: Latin American CTO Registry Analysis - Marcelo Harada Ribeiro, Carlos M. Campos , Lucio Padilla , Antonio Carlos B. da Silva , João Eduardo T. de Paula , Marco Alcantara , Ricardo Santiago , Franklin Hanna , Franciele R. da Silva , Karlyse C. Belli , Lorenzo Azzalini , Pedro P. de Oliveira , Gustavo N. Araujo , Vincenzo Sucato , Kambis Mashayekhi , Alfredo R. Galassi , Alexandre Abizaid , and Alexandre Quadros 1Heart Institute (InCor)Universidade de São Paulo (USP) São Paulo Brazil 2Instituto Prevent Senior, Sao Paulo São Paulo Brazil 3Interventional Cardiology Division Instituto Cardiovascular de Buenos Aires Buenos Aires (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundCoronary perforation is a life?threatening complication of acute percutaneous coronary intervention (PCI) for chronic total occlusions (CTO), but data on midterm outcomes are limited.Methods and ResultsData (...) (Journal of the American Heart Association)
12:38
Genetic Determinants of Body Mass Index and Fasting Glucose Are Mediators of Grade 1 Diastolic Dysfunction - Nataraja Sarma Vaitinadin, Mingjian Shi , Christian M. Shaffer , Eric Farber?Eger , Brandon D. Lowery , Vineet Agrawal , Deepak K. Gupta , Dan M. Roden , Quinn S. Wells , and Jonathan D. Mosley 1Department of Medicine Vanderbilt University Medical Center Nashville TN 2Department of Biomedical Informatics Vanderbilt University Medical Center Nashville TN 3Department of Pharmacology Vanderbilt University Nashville TN J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundEarly (grade 1) cardiac left ventricular diastolic dysfunction (G1DD) increases the risk for heart failure with preserved ejection fraction and may improve with aggressive risk factor modification. Type 2 (...) (Journal of the American Heart Association)
12:37
Neutrophil?to?Lymphocyte Ratios in Patients Undergoing Aortic Valve Replacement: The PARTNER Trials and Registries - Bahira Shahim, Björn Redfors , Brian R. Lindman , Shmuel Chen , Torsten Dahlen , Tamim Nazif , Samir Kapadia , Zachary M. Gertz , Aaron C. Crowley , Ditian Li , Vinod H. Thourani , Susheel K. Kodali , Alan Zajarias , Vasilis C. Babaliaros , Robert A. Guyton , Sammy Elmariah , Howard C. Herrmann , David J. Cohen , Michael J. Mack , Craig R. Smith , Martin B. Leon , and Isaac George 1Clinical Trials Center Cardiovascular Research Foundation New York NY 2Division of Cardiology NewYork?Presbyterian Hospital/Columbia University Medical Center New York NY 3Structural Heart and Valve (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe neutrophil?to?lymphocyte ratio (NLR) as a marker of systemic inflammation has been associated with worse prognosis in several chronic disease states, including heart failure. However, few data exist on the (...) (Journal of the American Heart Association)
12:37
Hydrophilic Versus Lipophilic Statin Treatments in Patients With Renal Impairment After Acute Myocardial Infarction - Min Hye Kang, Weon Kim , Jin Sug Kim , Kyung Hwan Jeong , Myung Ho Jeong , Jin?Yong Hwang , Seung Ho Hur , and Hyeon Seok Hwang 1Division of Nephrology Department of Internal Medicine Kyung Hee University Seoul Republic of Korea 2Division of Cardiology Department of Internal Medicine Kyung Hee University Seoul Republic of Korea 3Department of Internal Medicine and Heart Center Chonnam National University Hospital Gwangju Republic of Korea 4Department of Internal Medicine Gyeongsang National University Hospital Jinju Republic of Korea 5Division of Cardiology Keimyung University Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundHydrophilic and lipophilic statins have similar efficacies in treating coronary artery disease. However, specific factors relevant to renal impairment and different arterial pathogeneses could modify the (...) (Journal of the American Heart Association)
12:36
Lipoprotein(a) and Subclinical Vascular and Valvular Calcification on Cardiac Computed Tomography: The Atherosclerosis Risk in Communities Study - Olufunmilayo H. Obisesan, Minghao Kou , Frances M. Wang , Ellen Boakye , Yasuyuki Honda , S. M. Iftekhar Uddin , Omar Dzaye , Albert D. Osei , Olusola A. Orimoloye , Candace M. Howard?Claudio , Josef Coresh , Roger S. Blumenthal , Ron C. Hoogeveen , Matthew J. Budoff , Kunihiro Matsushita , Christie M. Ballantyne , and Michael J. Blaha 1Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease Baltimore MD 2Medstar Union Memorial Hospital Baltimore MD 3Tulane University School of Public Health and Tropical Medicine New Orleans LA 4Johns Hopkins Bloomberg School of Public (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundLipoprotein(a) (Lp(a)) is a potent causal risk factor for cardiovascular events and mortality. However, its relationship with subclinical atherosclerosis, as defined by arterial calcification, remains (...) (Journal of the American Heart Association)
12:36
Intervention Adherence in REHAB?HF: Predictors and Relationship With Physical Function, Quality of Life, and Clinical Events - M. Benjamin Nelson, Olivia N. Gilbert , Pamela W. Duncan , Dalane W. Kitzman , Gordon R. Reeves , David J. Whellan , Robert J. Mentz , Haiying Chen , Leigh Ann Hewston , Karen M. Taylor , and Amy M. Pastva 1Department of Internal Medicine Section on Cardiovascular Medicine Wake Forest School of Medicine Winston?Salem NC 2Department of Neurology Wake Forest School of Medicine Winston?Salem NC 3Department of Internal MedicineSection on GeriatricsWake Forest School of Medicine Winston?Salem NC 4Novant Health Heart and Vascular Institute Charlotte NC 5Department of Medicine Sidney Kimmel (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe REHAB?HF (Rehabilitation Therapy in Older Acute Heart Failure Patients) trial showed that a novel, early, transitional, tailored, progressive, multidomain physical rehabilitation intervention improved (...) (Journal of the American Heart Association)
12:36
Faculty Development Approaches for Life Support Courses: A Scoping Review - Ying?Chih Ko, Ming?Ju Hsieh , Adam Cheng , Kasper G. Lauridsen , Taylor L. Sawyer , Farhan Bhanji , Robert Greif 1Department of Emergency Medicine National Taiwan University Hospital Taipei Taiwan 2Departments of Pediatrics and Emergency Medicine University of Calgary Alberta Canada 3Research Center for Emergency Medicine Aarhus University Hospital Aarhus Denmark 4Emergency Department Randers Regional Hospital Randers Denmark 5Department of Anesthesiology and Critical Care Medicine Children's Hospital of Philadelphia Philadelphia PA 6University of Washington School of Medicine Seattle WA (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. The aim of this scoping review initiated by the Education, Implementation and Teams Task Force of the International Liaison Committee on Resuscitation was to identify faculty development approaches to improve (...) (Journal of the American Heart Association)
12:36
Validation of the WATCH?DM and TRS?HFDM Risk Scores to Predict the Risk of Incident Hospitalization for Heart Failure Among Adults With Type 2 Diabetes: A Multicohort Analysis - Matthew W. Segar, Kershaw V. Patel , Anne S. Hellkamp , Muthiah Vaduganathan , Yuliya Lokhnygina , Jennifer B. Green , Siu?Hin Wan , Ahmed A. Kolkailah , Rury R. Holman , Eric D. Peterson , Vaishnavi Kannan , Duwayne L. Willett , Darren K. McGuire , and Ambarish Pandey 1Department of Cardiology Texas Heart Institute Houston TX 2Department of Cardiology Houston Methodist DeBakey Heart and Vascular Center Houston TX 3Duke Clinical Research Institute Duke University School of Medicine Durham NC 4Brigham and Women’s Hospital Heart and Vascular Center Department of Medicine Harvard Medical (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe WATCH?DM (weight [body mass index], age, hypertension, creatinine, high?density lipoprotein cholesterol, diabetes control [fasting plasma glucose], ECG QRS duration, myocardial infarction, and coronary (...) (Journal of the American Heart Association)
12:36
Underuse of Catheter Ablation as First?Line Therapy for Supraventricular Tachycardia - Lucas Hollanda Oliveira, Mateus dos Santos Viana , Christian Moreno Luize , Ricardo Sobral de Carvalho , Claudio Cirenza , Cristiano de Oliveira Dietrich , Luis Claudio Correia , Claudio das Virgens , Juliana Medeiros Filgueiras , Mauricio Barreto , Emerson Porto , Enia Coutinho , and Ângelo de Paola 1From Clinical Cardiac Electrophysiology Federal University of São Paulo São Paulo Brazil 2Fundação Bahiana de Cardiologia Salvador Brazil 3Hospital Aliança Salvador Brazil 4Bahiana Medical and Public Health School Salvador Brazil 5Hospital Moriah São Paulo (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundCatheter ablation (CA) is a safe, effective, cost?effective technique and may be considered a first?line strategy for the treatment of symptomatic supraventricular tachycardias (SVT). Despite the high prospect (...) (Journal of the American Heart Association)
12:36
Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans - Hao Zhang, K. Lockhart Jamieson , Justin Grenier , Anish Nikhanj , Zeyu Tang , Faqi Wang , Shaohua Wang , Jonathan G. Seidman , Christine E. Seidman , Richard Thompson , John M. Seubert , and Gavin Y. Oudit 1Division of Cardiology Department of Medicine Faculty of Medicine and DentistryEdmonton Alberta Canada 2Mazankowski Alberta Heart Institute Edmonton Alberta Canada 3Department of Pharmacology Faculty of Medicine and DentistryEdmonton Alberta Canada 4Department of Biomedical Engineering Faculty of Medicine and DentistryEdmonton Alberta Canada 5Division of Cardiac Surgery Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundMyocardial iron deficiency (MID) in heart failure (HF) remains largely unexplored. We aim to establish defining criterion for MID, evaluate its pathophysiological role, and evaluate the applicability of (...) (Journal of the American Heart Association)
12:34
Potential Impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on Contemporary Practice: A Cross?Sectional Analysis From NCDR PINNACLE Registry - Aliza Hussain, Salim S. Virani , Luke Zheng , Ty J. Gluckman , William B. Borden , Frederick A. Masoudi , and Thomas M. Maddox 1Section of Cardiology Department of Medicine Baylor College of Medicine Houston TX 2Section of Cardiology Michael E. DeBakey Veterans Affairs Hospital Houston TX 3BAIM Institute for Clinical Research Boston MA 4Center for Cardiovascular Analytics, Research and Data Science Providence Heart InstituteProvidence St Joseph Health Portland OR 5Department of Medicine George Washington University Washington DC 6Division of Cardiology University of Colorado Anschutz (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundClinical implications of change in the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline on the diagnosis and management of hypertension, compared with recommendations by (...) (Journal of the American Heart Association)

2 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:07
Sex Differences in Temporal Trends of Cardiovascular Health in Young US Adults - So Mi Jemma Cho, Sara Haidermota , Michael C. Honigberg , and Pradeep Natarajan 1Program in Medical and Population Genetics and the Cardiovascular Disease Initiative Broad Institute of MIT and Harvard Cambridge MA 2Cardiovascular Research Center Massachusetts General Hospital Boston MA 3Department of Preventive Medicine Yonsei University College of Medicine Seoul Korea 4Integrative Research Center for Cerebrovascular and Cardiovascular Diseases Seoul Korea 5Cardiology Division Department of Medicine Harvard Medical School Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundFavorable cardiovascular health (CVH) in young adulthood has been associated with lower future cardiovascular risk. We determined whether CVH and its sex differences in young adults have changed from 2007 to (...) (Journal of the American Heart Association)

1 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

03:34
Blood Pressure–Lowering Effects of Omega?3 Polyunsaturated Fatty Acids: Are These the Missing Link to Explain the Relationship Between Omega?3 Polyunsaturated Fatty Acids and Cardiovascular Disease? - Marc George, and Ajay Gupta 1 Department of Clinical Pharmacology and Therapeutics University College London Hospitals NHS Foundation Trust London United Kingdom 2 Institute of Cardiovascular Science University College London London United Kingdom 3 Department of Clinical Pharmacology William Harvey Research Institute, Queen Mary University of London London United Kingdom 4 Royal London Hospital Barts Health NHS Trust London United Kingdom J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
03:00
Omega?3 Polyunsaturated Fatty Acids Intake and Blood Pressure: A Dose?Response Meta?Analysis of Randomized Controlled Trials - Xin Zhang, Jennifer A. Ritonja , Na Zhou , Bingshu E. Chen , and Xinzhi Li 1School of Pharmacy and State Key Laboratory of Quality Research in Chinese Medicines Macau University of Science and Technology Taipa Macau China 2Department of Public Health Sciences and Canadian Cancer Trials Group Queen's University Kingston Ontario Canada J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundCurrent evidence might support the use of omega?3 fatty acids (preferably docosahexaenoic acid and eicosapentaenoic acid) for lowering blood pressure (BP), but the strength and shape of the dose?response (...) (Journal of the American Heart Association)

28 May

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

04:23
Effects of Sodium Nitroprusside Administered Via a Subdural Intracranial Catheter on the Microcirculation, Oxygenation, and Electrocortical Activity of the Cerebral Cortex in a Pig Cardiac Arrest Model - Hyoung Youn Lee, Yong Hun Jung , Najmiddin Mamadjonov , Kyung Woon Jeung , Min Chul Kim , Kyung Seob Lim , Chang?Yeop Jeon , Youngjeon Lee , and Hyung Joong Kim 1Trauma Center Chonnam National University Hospital Gwangju Republic of Korea 2Department of Emergency Medicine Chonnam National University Hospital Gwangju Republic of Korea 3Department of Emergency Medicine Chonnam National University Medical School Gwangju Republic of Korea 4Department of Medical Science Chonnam National University Graduate School Gwangju Republic of Korea 5Division of Cardiology Department of Internal Medicine (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundPostischemic cerebral hypoperfusion has been indicated as an important contributing factor to secondary cerebral injury after cardiac arrest. We evaluated the effects of sodium nitroprusside administered via (...) (Journal of the American Heart Association)
04:22
Renin?Angiotensin Aldosterone System Inhibitors and COVID?19: A Systematic Review and Meta?Analysis Revealing Critical Bias Across a Body of Observational Research - Jordan Loader, Frances C. Taylor , Erik Lampa , and Johan Sundström 1Department of Medical Sciences Uppsala University Uppsala Sweden 2Inserm U1300 – HP2 CHU Grenoble Alpes Grenoble France 3Baker Heart and Diabetes Institute Melbourne Victoria Australia 4Mary MacKillop Institute for Health Research, Australian Catholic University Melbourne Victoria Australia 5The George Institute for Global Health University of New South Wales Sydney Australia J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundRenin?angiotensin aldosterone system (RAAS) inhibitor—COVID?19 studies, observational in design, appear to use biased methods that can distort the interaction between RAAS inhibitor use and COVID?19 risk. This (...) (Journal of the American Heart Association)
04:21
Impact of Racial Disparities in Preoperative Cardiovascular Evaluation and Surgical Outcomes in Patients Undergoing Metabolic and Bariatric Surgery: A Retrospective Cohort Analysis - Kaitlyn D. Ibrahim, Lauren A. Tragesser , Rohit Soans , Abdullah Haddad , Vikram J. Eddy , Joseph McComb , Martin G. Keane , and Isaac R. Whitman 1Lewis Katz School of Medicine at Temple University Philadelphia PA 2Division of Cardiology Temple University Hospital Philadelphia PA 3Main Line Health Broomall PA 4Division of Bariatric Surgery Temple University Hospital Philadelphia PA 5Division of Anesthesiology Temple University Hospital Philadelphia (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundWe investigated preoperative referral patterns, rates of cardiovascular testing, surgical wait times, and postoperative outcomes in White versus Black, Hispanic, or other racial or ethnic groups of patients (...) (Journal of the American Heart Association)

27 May

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

13:12
Marital Status and Subclinical Coronary Atherosclerosis in Asymptomatic Individuals - Soe Hee Ann, Hyeji Lee , Kyung Sun Park , Young?Jee Jeon , Eun Ji Park , Sangwoo Park , Yong?Giun Kim , Yongjik Lee , Seong Hoon Choi , Woon Jung Kwon , and Gyung?Min Park 1Department of Cardiology Ulsan University HospitalUniversity of Ulsan College of Medicine Ulsan Republic of Korea 2Department of Emergency Medicine Ulsan University HospitalUniversity of Ulsan College of Medicine Ulsan Republic of Korea 3Department of Nephrology Ulsan University HospitalUniversity of Ulsan College of Medicine Ulsan Republic of Korea 4Department of Family Medicine Ulsan University HospitalUniversity of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundData are limited on the association between marital status and subclinical coronary atherosclerosis. This study investigated the influence of marital status on subclinical coronary atherosclerosis detected (...) (Journal of the American Heart Association)
13:12
Total Cardiovascular and Limb Events and the Impact of Polyvascular Disease in Chronic Symptomatic Peripheral Artery Disease - Michael Szarek, Connie Hess , Manesh R. Patel , W. Schuyler Jones , Jeffrey S. Berger , Iris Baumgartner , Brian Katona , Kenneth W. Mahaffey , Lars Norgren , Juuso Blomster , Frank W. Rockhold , Judith Hsia , F. Gerry R. Fowkes , and Marc P. Bonaca 1CPC Clinical Research Aurora CO 2Department of Medicine University of Colorado Aurora CO 3SUNY Downstate Health Sciences University Brooklyn NY 4Duke Clinical Research Institute Durham NC 5Division of Cardiology Duke University Medical Center Durham NC 6New York University School of Medicine New York NY 7Swiss Cardiovascular (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundPeripheral artery disease (PAD) is associated with heightened risk for major adverse cardiovascular and limb events, but data on the burden of risk for total (first and potentially subsequent) events, and (...) (Journal of the American Heart Association)
13:12
Framingham and American College of Cardiology/American Heart Association Pooled Cohort Equations, High?Sensitivity Troponin T, and N?Terminal Pro–Brain?Type Natriuretic Peptide for Predicting Atherosclerotic Cardiovascular Events Across the Spectrum of Kidney Dysfunction - Benjamin Lidgard, Leila R. Zelnick , Alan Go , Kevin D. O’Brien , Nisha Bansal 1Department of Medicine University of Washington Seattle WA 2Kaiser Permanente Division of ResearchNorthern California Oakland CA, the CRIC Study Investigators * Lawrence J. Appel, Jing Chen, Debbie L. Cohen, Harold I. Feldman, James P. Lash, Robert G. Nelson, Panduranga S. Rao, Mahboob Rahman, Vallabh O. Shah, and Mark L. Unruh J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundContemporary guidelines recommend using atherosclerotic cardiovascular disease screening tools to guide primary prevention. The performance of these scores is not well known in patients with moderate to (...) (Journal of the American Heart Association)
13:11
Same?Day Discharge After Transcatheter Aortic Valve Implantation: Insights from the Nationwide Readmission Database 2015 to 2019 - Salman Zahid, Devesh Rai , Mian Tanveer Ud Din , Muhammad Zia Khan , Waqas Ullah , Muhammad Usman Khan , Samarthkumar Thakkar , Ahmed Hussein , Bipul Baibhav , Mohan Rao , Farhad Abtahian , Deepak L. Bhatt , and Jeremiah P. Depta 1Sands?Constellation Heart InstituteRochester General Hospital Rochester NY 2Department of Medicine Allegheny Health Network Pittsburgh PA 3Division of Cardiovascular Medicine West Virginia University Heart & Vascular Institute Morgantown WV 4Department of Cardiovascular Medicine Jefferson University Hospitals Philadelphia PA 5Brigham and Women’s Hospital Heart & (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThere is a paucity of data on the feasibility of same?day discharge (SDD) following transcatheter aortic valve implantation (TAVI) at a national level.Methods and ResultsThis study used data from the (...) (Journal of the American Heart Association)
13:11
Cangrelor Use Patterns and Transition to Oral P2Y12 Inhibitors Among Patients With Myocardial Infarction: Initial Results From the CAMEO Registry - Jennifer A. Rymer, Deepak L. Bhatt , Dominick J. Angiolillo , Miguel Diaz , Kirk N. Garratt , Ron Waksman , Laura Edwards , Gudaye Tasissa , Khalid Salahuddin , Hijrah El?Sabae , Carmen Dell’Anna , Linda Davidson?Ray , Jeffrey B. Washam , E. Magnus Ohman , and Tracy Y. Wang 1Division of Cardiology Duke University Medical Center Durham NC 2Duke Clinical Research Institute Durham NC 3Division of Cardiovascular Medicine Brigham and Women’s HospitalHarvard Medical School Boston MA 4Division of Cardiology University of Florida Jacksonville FL 5Palmetto General Hospital Hialeah FL 6Division of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundIn clinical trials, cangrelor has been shown to reduce percutaneous coronary intervention–related ischemic complications without increasing major bleeding. This study was performed to examine cangrelor use (...) (Journal of the American Heart Association)
13:11
Genetic Architecture of Plasma Alpha?Aminoadipic Acid Reveals a Relationship With High?Density Lipoprotein Cholesterol - Mingjian Shi, Chuan Wang , Hao Mei , Marinella Temprosa , Jose C. Florez , Mark Tripputi , Jordi Merino , Loren Lipworth , Xiao?Ou Shu , Robert E. Gerszten , Thomas J. Wang , Joshua A. Beckman , Jorge L. Gamboa , Jonathan D. Mosley , Jane F. Ferguson , and 1Department of Biomedical Informatics Vanderbilt University Medical Center Nashville TN 2Division of Cardiovascular Medicine Department of Medicine Vanderbilt University Medical Center Nashville TN 3Department of Data Science School of Population Health University of Mississippi Medical Center Jackson MS 4Department of Biostatistics and (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundElevated plasma levels of alpha?aminoadipic acid (2?AAA) have been associated with the development of type 2 diabetes and atherosclerosis. However, the nature of the association remains unknown.Methods and (...) (Journal of the American Heart Association)
13:10
Temporal Changes of Stable High?Sensitivity Cardiac Troponin T Levels and Prognosis - Andreas Roos, Gustaf Edgren , and Martin J. Holzmann 1Department of Medicine Karolinska Institutet, Solna Stockholm Sweden 2Department of Emergency and Reparative Medicine Karolinska University Hospital, Huddinge Stockholm Sweden 3Department of Medicine Clinical Epidemiology Division Karolinska Institutet, Solna Stockholm Sweden 4 Department of Cardiology, Södersjukhuset Stockholm Sweden J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe prognostic implications of temporal change of previously stable high?sensitivity cardiac troponin concentrations are unknown. We investigated the prognosis associated with temporal changes of stable (...) (Journal of the American Heart Association)
13:10
Longitudinal Associations Between Fat?Derived Dietary Patterns and Early Markers of Cardiovascular Disease Risk in the UK Biobank Study - Barbara Brayner, Michelle A. Keske , Gunveen Kaur , Sheikh Mohammed Shariful Islam , Aurora Perez?Cornago , Carmen Piernas , and Katherine M. Livingstone 1School of Exercise and Nutrition Sciences Institute for Physical Activity and Nutrition Deakin University Geelong Victoria Australia 2Cancer Epidemiology Unit Nuffield Department of Population Health University of Oxford, Old Road Campus Headington, Oxford United Kingdom 3Nuffield Department of Primary Care Health Sciences Medical Sciences Division Radcliffe Primary Care Building Radcliffe Observatory QuarterUniversity of Oxford United (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundAlthough the impact of dietary fats on cardiovascular disease (CVD) risk is widely researched, longitudinal associations between dietary patterns (DPs) based on fat type and early markers of CVD risk remain (...) (Journal of the American Heart Association)
13:09
Increases in Hepatokine Selenoprotein P Levels Are Associated With Hepatic Hypoperfusion and Predict Adverse Prognosis in Patients With Heart Failure - Ryohei Takeishi, Tomofumi Misaka , Yasuhiro Ichijo , Shinji Ishibashi , Mitsuko Matsuda , Yukio Yamadera , Himika Ohara , Yukiko Sugawara , Yu Hotsuki , Koichiro Watanabe , Fumiya Anzai , Yu Sato , Takamasa Sato , Masayoshi Oikawa , Atsushi Kobayashi , Takayoshi Yamaki , Kazuhiko Nakazato , Akiomi Yoshihisa , and Yasuchika Takeishi 1Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan 2Department of Clinical Laboratory Medicine Fukushima Medical University Hospital Fukushima Japan 3Department of Clinical Laboratory Sciences Fukushima Medical University School (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundAlthough multiorgan networks are involved in the pathophysiology of heart failure (HF), interactions of the heart and the liver have not been fully understood. Hepatokines, which are synthesized and secreted (...) (Journal of the American Heart Association)
13:09
Cerebral Circulation Time After Thrombectomy: A Potential Predictor of Outcome After Recanalization in Acute Stroke - Jia?Qi Wang, Ying?Jia Wang , Jin Qiu , Wei Li , Xian?Hui Sun , Yong?Gang Zhao , Xin Liu , Zi?Ai Zhao , Liang Liu , Thanh N. Nguyen , and Hui?Sheng Chen 1Department of Neurology General Hospital of Northern Theater Command Shenyang China 2Neurology, Radiology, Boston Medical Center Boston MA J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundDespite successful recanalization, up to half of patients with acute ischemic stroke caused by large?vessel occlusion treated with endovascular treatment (EVT) do not recover to functional independence. We (...) (Journal of the American Heart Association)
13:09
Impact of Adenosine on Wavefront Propagation in Persistent Atrial Fibrillation: Insights From Global Noncontact Charge Density Mapping of the Left Atrium - Michael T. B. Pope, Pawel Kuklik , Andre Briosa e Gala , Milena Leo , Michael Mahmoudi , John Paisey , and Timothy R. Betts 1Oxford University Hospitals NHS Foundation Trust Oxford United Kingdom 2University of Southampton United Kingdom 3Department of Cardiology Asklepios Clinic St. Georg Hamburg Germany 4Southampton University Hospitals NHS Foundation Trust Southampton United Kingdom 5University of Oxford Biomedical Research Centre Oxford United (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundAdenosine shortens action potential duration and refractoriness and provokes atrial fibrillation. This study aimed to evaluate the effect of adenosine on mechanisms of wavefront propagation during atrial (...) (Journal of the American Heart Association)
13:09
Impact of Blood Pressure in the Early 40s on Left Atrial Volumes in the Mid?60s: Data From the ACE 1950 Study - Peter Selmer Rønningen, Trygve Berge , Magnar Gangås Solberg , Steve Enger , Mohammad Osman Pervez , Eivind Bjørkan Orstad , Brede Kvisvik , Erika Nerdrum Aagaard , Magnus Nakrem Lyngbakken , Inger Ariansen , Helge Røsjø , Kjetil Steine , and Arnljot Tveit 1Department of Medical Research Bærum HospitalVestre Viken Hospital Trust Gjettum Norway 2Faculty of Medicine Institute of Clinical Medicine University of Oslo Oslo Norway 3Division of Medicine Department of Cardiology Akershus University Hospital Lørenskog Norway 4Deparment of Chronic Diseases and Ageing Norwegian Institute of Public Health (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundEchocardiographic measures of left atrial volumes are powerful predictors of cardiovascular events and important for assessing diastolic dysfunction. Despite this, there is limited knowledge of factors (...) (Journal of the American Heart Association)
13:08
Impact of Fontan Fenestration on Long?Term Outcomes: A Propensity Score–Matched Analysis - Michael Daley, Edward Buratto , Gregory King , Leeanne Grigg , Ajay Iyengar , Nelson Alphonso , Andrew Bullock , David S. Celermajer , Julian Ayer , Terry Robertson , Yves d’Udekem , and Igor E. Konstantinov 1Department of Cardiac Surgery Royal Children’s Hospital Melbourne Australia 2Department of Paediatrics University of Melbourne Melbourne Australia 3Heart Research Group Murdoch Children’s Research Institute Melbourne Australia 4Department of Cardiology Royal Melbourne Hospital Melbourne Australia 5Green Lane Paediatric and Congenital Cardiac Service Starship Children’s Health Auckland (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe long?term impact of fenestration at the time of Fontan operation remains unclear. We aimed to review the early and long?term impact of Fontan fenestration in the Australia and New Zealand cohort.Methods (...) (Journal of the American Heart Association)
13:07
Patient? and Process?Related Contributors to the Underuse of Aortic Valve Replacement and Subsequent Mortality in Ambulatory Patients With Severe Aortic Stenosis - Laura Flannery, Muhammad Etiwy , Alexander Camacho , Ran Liu , Nilay Patel , Arpi Tavil?Shatelyan , Varsha K. Tanguturi , Jacob P. Dal?Bianco , Evin Yucel , Rahul Sakhuja , Arminder S. Jassar , Nathaniel B. Langer , Ignacio Inglessis , Jonathan J. Passeri , Judy Hung , and Sammy Elmariah 1Cardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA 2Division of Cardiac Surgery Department of Surgery Massachusetts General HospitalHarvard Medical School Boston (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundMany patients with severe aortic stenosis (AS) and an indication for aortic valve replacement (AVR) do not undergo treatment. The reasons for this have not been well studied in the transcatheter AVR era. We (...) (Journal of the American Heart Association)
13:07
Association of Vascular Properties With the Brain White Matter Hyperintensity in Middle?Aged Population - Yousef Hannawi, Dhananjay Vaidya , Lisa R. Yanek , Michelle C. Johansen , Brian G. Kral , Lewis C. Becker , Diane M. Becker , and Paul A. Nyquist 1Division of Cerebrovascular Diseases and Neurocritical Care Department of Neurology The Ohio State University Columbus OH 2GeneSTAR Research Program Department of Medicine Johns Hopkins University School of Medicine Baltimore MD 3Department of Neurology Johns Hopkins University School of Medicine Baltimore MD 4Department of Neurosurgery Johns Hopkins University School of Medicine Baltimore MD 5Division of Neurocritical Care Department of (...) J Am Heart Assoc

Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundThe periventricular white matter is more sensitive to the systemic hemodynamic alterations than the deep white matter because of differences in its vascular structure and systemic circulation relationship. (...) (Journal of the American Heart Association)

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