5 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 13:14
  Association of Pulmonary Function With Late?Life Cardiac Function and Heart Failure Risk: The ARIC Study - Sergio H. R. Ramalho, Brian L. Claggett , George R. Washko , Raul San Jose Estepar , Patricia P. Chang , Dalane W. Kitzman , Gerson Cipriano Junior , Scott D. Solomon , Hicham Skali , and Amil M. Shah 1Division of Cardiovascular Medicine Brigham and Women’s Hospital Boston MA 2Health Sciences and Technologies Program – University of Brasilia Brasília Brazil 3Division of Pulmonary and Critical Care Medicine Brigham and Women’s Hospital Boston MA 4Department of Radiology Brigham and Women’s Hospital Boston MA 5University of North Carolina Chapel Hill NC 6Wake Forest School of Medicine (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundPulmonary and cardiac functions decline with age, but the associations of pulmonary dysfunction with cardiac function and heart failure (HF) risk in late life is not known. We aimed to determine the associations of percent (...) (Journal of the American Heart Association)
• 13:14
  Gravitational Dose?Response Curves for Acute Cardiovascular Hemodynamics and Autonomic Responses in a Tilt Paradigm - Richard S. Whittle, Nathan Keller , Eric A. Hall , Hrudayavani S. Vellore , Lindsay M. Stapleton , Katherine H. Findlay , Bonnie J. Dunbar , and Ana Diaz?Artiles 1Department of Aerospace Engineering Texas A&M University College Station TX 2Department of Health and Kinesiology Texas A&M University College Station TX 3Department of Biomedical Engineering Texas A&M University College Station TX 4Independent Researcher College Station TX J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe cardiovascular system is strongly dependent on the gravitational environment. Gravitational changes cause mechanical fluid shifts and, in turn, autonomic effectors influence systemic circulation and cardiac control. We (...) (Journal of the American Heart Association)
• 13:13
  Correction to: One?Month Dual Antiplatelet Therapy After Bioresorbable Polymer Everolimus?Eluting Stents in High Bleeding Risk Patients J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 13:12
  Correction to: Ischemic Stroke Severity and Mortality in Patients With and Without Atrial Fibrillation J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 13:12
  Correction to: Clinical Impact of Intraprocedural Stent Thrombosis During Percutaneous Coronary Intervention in Patients Treated With Potent P2Y12 inhibitors – a VALIDATE?SWEDEHEART Substudy J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)

4 July

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 11:06
  Highlights in ASCVD Primary Prevention for 2021 - Tamar S. Polonsky, Amit Khera , Michael D. Miedema , Douglas D. Schocken , and Peter W. F. Wilson 1 Department of Medicine University of Chicago Medicine Chicago IL 2 Department of Medicine University of Texas, Southwestern Dallas TX 3 Allina Health Minneapolis MN 4 Department of Medicine Duke University Durham NC 5 Department of Medicine Emory University Atlanta GA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. This review examines key studies published in 2021 that are related to primary prevention of atherosclerotic cardiovascular disease (ASCVD). Major randomized clinical trials (RCTs) concerning traditional risk factors or ASCVD events, (...) (Journal of the American Heart Association)

29 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 13:08
  Alcohol Consumption Is Associated With Postablation Recurrence but Not Changes in Atrial Substrate in Patients With Atrial Fibrillation: Insight from a High?Density Mapping Study - Yuichiro Sagawa, Yasutoshi Nagata , Naoyuki Miwa , Takanori Yamaguchi , Keita Watanabe , Masakazu Kaneko , Tomofumi Nakamura , Toshihiro Nozato , Takashi Ashikaga , Masahiko Goya , and Tetsuo Sasano 1 Department of Cardiology Japanese Red Cross Musashino Hospital Tokyo Japan 2 Cardiovascular Center Tsuchiura Kyodo Hospital Tsuchiura Japan 3 Department of Cardiovascular Medicine Saga University Saga Japan 4 Department of Cardiovascular Medicine Tokyo Medical and Dental University Tokyo (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe association between alcohol consumption, atrial substrate, and outcomes after atrial fibrillation (AF) ablation remains controversial. This study evaluated the impacts of drinking on left atrial substrate and AF recurrence (...) (Journal of the American Heart Association)
• 12:45
  Bidirectional Longitudinal Relationships Between Arterial Stiffness and Hypertension Are Independent of Those Between Arterial Stiffness and Diabetes: A Large?Scale Prospective Observational Study in Employees of a Japanese Company - Hiroki Nakano, Kazuki Shiina , Takamichi Takahashi , Masatsune Fujii , Yoichi Iwasaki , Chisa Matsumoto , Akira Yamashina , Taishiro Chikamori , and Hirofumi Tomiyama 1 Department of Cardiology Tokyo Medical University Tokyo Japan 2 Division of Preemptive Medicine for Vascular Damage Tokyo Medical University Tokyo Japan 3 Department of Nursing Kiryu University Gunma Japan J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundHypertension and diabetes frequently coexist; however, it has not yet been clarified if the bidirectional longitudinal relationships between arterial stiffness and hypertension are independent of those between arterial (...) (Journal of the American Heart Association)
• 12:45
  Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality - Patricia A. Pellikka, Ratnasari Padang , Christopher G. Scott , Shannon M. E. Murphy , Rosalind Fabunmi , and Jeremy J. Thaden 1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN 2 Department of Quantitative Health Sciences Mayo Clinic Rochester MN 3 Edwards Lifesciences Irvine CA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundMany patients with symptomatic severe aortic stenosis do not undergo aortic valve replacement (AVR) despite clinical guidelines. This study analyzed the association of managing provider type with cardiac specialist follow?up, (...) (Journal of the American Heart Association)
• 12:45
  Novel Risk Prediction Model to Determine Adverse Heart Failure Outcomes in Arrhythmogenic Right Ventricular Cardiomyopathy - Shi Chen, Liang Chen , Ardan M. Saguner , Kai Chen , Deniz Akdis , Alessio Gasperetti , Corinna Brunckhorst , Hanwei Tang , Guangran Guo , Man Rao , Xiangjie Li , Jiangping Song , Firat Duru , and Shengshou Hu 1 State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China 2 University Heart Center Zurich Zurich Switzerland 3 Center for Integrative Human Physiology University of Zurich Zurich Switzerland 4 School of Statistics and Data Science Nankai University (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundPatients with arrhythmogenic right ventricular cardiomyopathy are at risk for life?threatening ventricular tachyarrhythmias, but progressive heart failure (HF) may occur in later stages of disease. This study aimed to (...) (Journal of the American Heart Association)
• 12:45
  Neuropeptide?Y Levels in ST?Segment–Elevation Myocardial Infarction: Relationship With Coronary Microvascular Function, Heart Failure, and Mortality - Thomas Gibbs, Nidi Tapoulal , Mayooran Shanmuganathan , Matthew K. Burrage , Alessandra Borlotti , Adrian P. Banning , Robin P. Choudhury , Stefan Neubauer , Rajesh K. Kharbanda , Vanessa M. Ferreira , Keith M. Channon , and Neil Herring 1 Department of Physiology, Anatomy and Genetics, Burdon Sanderson Cardiac Science Centre University of Oxford United Kingdom 2 Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence University of Oxford United Kingdom 3 Oxford Acute Vascular Imaging Centre University of Oxford United (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe sympathetic cotransmitter, neuropeptide Y (NPY), is released into the coronary sinus during ST?segment–elevation myocardial infarction and can constrict the coronary microvasculature. We sought to establish whether (...) (Journal of the American Heart Association)
• 12:44
  Inhibiting Succinate Release Worsens Cardiac Reperfusion Injury by Enhancing Mitochondrial Reactive Oxygen Species Generation - Alexander S. Milliken, Sergiy M. Nadtochiy , and Paul S. Brookes 1 Department of Pharmacology and Physiology University of Rochester Medical Center Rochester NY 2 Department of Anesthesiology and Perioperative Medicine University of Rochester Medical Center Rochester NY J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe metabolite succinate accumulates during cardiac ischemia. Within 5 minutes of reperfusion, succinate returns to baseline levels via both its release from cells and oxidation by mitochondrial complex II. The latter drives (...) (Journal of the American Heart Association)
• 12:44
  B?Type Natriuretic Peptide and Long?Term Cardiovascular Mortality in Patients With Coronary Heart Disease - Ralph A. H. Stewart, Adrienne Kirby , Harvey D. White , Simone L. Marschner , Malcolm West , Peter L. Thompson , David Sullivan , Edward Janus , David Hunt , Leonard Kritharides , Anthony Keech , John Simes , and Andrew M. Tonkin 1 Green Lane Cardiovascular Service Auckland City Hospital Auckland New Zealand 2 National Health and Medical Research Council Clinical Trials Centre University of Sydney Camperdown Australia 3 Department of Medicine University of Queensland Brisbane Australia 4 School of Population Health University of Western Australia Perth Australia 5 Department of Clinical (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe plasma concentration of B?type natriuretic peptide (BNP) is a strong predictor of adverse cardiovascular events. The aim of this study was to determine whether the association between plasma BNP concentration and (...) (Journal of the American Heart Association)
• 12:44
  Utility of Updated Japanese Circulation Society Guidelines to Diagnose Isolated Cardiac Sarcoidosis - Kimi Sato, Naoto Kawamatsu , Masayoshi Yamamoto , Tomoko Machino?Ohtsuka , Tomoko Ishizu , and Masaki Ieda 1 Department of Cardiology, Faculty of Medicine University of Tsukuba Japan J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundIn the population with cardiac sarcoidosis (CS), approximately one third lacks extracardiac involvement and is considered to have isolated CS. Recently, the Japanese Circulation Society updated the diagnostic criteria for CS, (...) (Journal of the American Heart Association)
• 12:44
  Left Ventricular Diastolic Dysfunction and Progression of Chronic Kidney Disease: Analysis of KNOW?CKD Data - Eunjeong Kang, Sung Woo Lee , Hyunjin Ryu , Minjung Kang , Seonmi Kim , Sue K. Park , Ji Yong Jung , Kyu?Beck Lee , Seung Hyeok Han , Curie Ahn , and Kook?Hwan Oh 1 Department of Internal Medicine Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine Seoul South Korea 2 Department of Internal Medicine Uijeongbu Eulji University Medical Center, Uijeongbu?si Gyeonggi?do South Korea 3 Department of Internal Medicine Seoul National University College of Medicine Seoul South Korea 4 Department of Preventive Medicine Seoul National University College of Medicine (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundFew studies have examined the association between the early diastolic mitral inflow velocity/early diastolic mitral annulus velocity ratio (E/e’) and chronic kidney disease progression.Methods and ResultsWe reviewed data from (...) (Journal of the American Heart Association)
• 12:44
  Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism - Tomomi Ueda, Yuya Tsurutani , Jun Osada , Kosuke Inoue , Yoshitomo Hoshino , Masato Ono , Kazuki Nakai , Jun Saito , Kazuhiko Yumoto , and Tetsuo Nishikawa 1 Endocrinology and Diabetes Center Yokohama Rosai Hospital Yokohama Japan 2 Department of Cardiovascular Medicine Yokohama Rosai Hospital Yokohama Japan 3 Department of Social Epidemiology, Graduate School of Medicine Kyoto University Kyoto Japan 4 Nishikawa Clinic Yokohama Japan J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundPrimary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement. A few studies have compared the cardioprotective effects between (...) (Journal of the American Heart Association)
• 12:44
  Late Outcomes of Patients With Prehospital ST?Segment Elevation and Appropriate Cardiac Catheterization Laboratory Nonactivation - Amir Faour, Reece Pahn , Callum Cherrett , Oliver Gibbs , Karen Lintern , Christian J. Mussap , Rohan Rajaratnam , Dominic Y. Leung , David A. Taylor , Steven C. Faddy , Sidney Lo , Craig P. Juergens , and John K. French 1 Department of Cardiology, Liverpool Hospital Sydney New South Wales 2 The University of New South Wales Sydney New South Wales 3 Western Sydney University Sydney New South Wales 4 Ingham Institute Sydney New South Wales 5 New South Wales Ambulance Sydney New South (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundPatients with suspected ST?segment–elevation myocardial infarction (STEMI) and cardiac catheterization laboratory nonactivation (CCL?NA) or cancellation have reportedly similar crude and higher adjusted risks of death compared (...) (Journal of the American Heart Association)
• 12:44
  Diastolic Filling Time, Chronotropic Response, and Exercise Capacity in Heart Failure and Preserved Ejection Fraction With Sinus Rhythm - Kazuki Kagami, Masaru Obokata , Tomonari Harada , Toshimitsu Kato , Naoki Wada , Takeshi Adachi , and Hideki Ishii 1 Department of Cardiovascular Medicine Gunma University Graduate School of Medicine Maebashi Gunma Japan 2 Division of Cardiovascular Medicine National Defense Medical College Tokorozawa, Saitama Japan 3 Department of Rehabilitation Medicine Gunma University Graduate School of Medicine Maebashi Gunma Japan J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundExercise?induced high heart rate may impair exercise tolerance by reducing diastolic filling time and ventricular filling in heart failure with preserved ejection fraction (HFpEF). Given the importance of chronotropic response, (...) (Journal of the American Heart Association)
• 12:43
  Predicting Heart Failure in Arrhythmogenic Right Ventricular Cardiomyopathy - Weijia Wang, and Hugh Calkins 1 Division of Cardiology, Department of Medicine Johns Hopkins University Baltimore MD J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 12:43
  Association Between High?Sensitivity C?Reactive Protein and Prognosis in Different Periods After Ischemic Stroke or Transient Ischemic Attack - Yu Wang, Jiejie Li , Yuesong Pan , Mengxing Wang , Xia Meng , and Yongjun Wang 1 Department of Neurology Beijing Tiantan Hospital, Capital Medical University Beijing China 2 China National Clinical Research Center for Neurological Diseases Beijing China 3 Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical Sciences Beijing China J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe aim of this study was to investigate the association between hsCRP (high?sensitivity C?reactive protein) and prognosis over time after stroke onset.Methods and ResultsIn this prespecified prospective substudy of the Third (...) (Journal of the American Heart Association)
• 12:43
  Translating Clinical Guidelines Into Care Delivery Innovation: The Importance of Rigorous Methods for Generating Evidence - Adam N. Berman, and Jason H. Wasfy 1 Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital Harvard Medical School Boston MA 2 Cardiology Division, Department of Medicine, Massachusetts General Hospital Harvard Medical School Boston MA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 12:43
  Misdiagnosis of Thoracic Aortic Emergencies Occurs Frequently Among Transfers to Aortic Referral Centers: An Analysis of Over 3700 Patients - George J. Arnaoutakis, Takuya Ogami , Edgar Aranda?Michel , Yancheng Dai , Reed Holmes , Thomas M. Beaver , Derek Serna?Gallegos , Tomas D. Martin , Forozan Navid , Sarah Yousef , and Ibrahim Sultan 1 University of Florida Health Gainsville FL 2 Division of Cardiac Surgery, Department of Cardiothoracic Surgery University of Pittsburgh Pittsburgh PA USA 3 Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundAcute aortic syndromes may be prone to misdiagnosis by nonreferral aortic centers with less diagnostic experience. We evaluated regional variability in these misdiagnosis trends among patients transferred to different regional (...) (Journal of the American Heart Association)
• 12:42
  Sex?Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca2+ Handling - Celio Damacena de Angelis, Benney T. Endoni , Daniel Nuno , Kathryn Lamping , Johannes Ledolter , Olha M. Koval , and Isabella M. Grumbach 1 Department of Internal Medicine, Abboud Cardiovascular Research Center University of Iowa Iowa City IA 2 Department of Pharmacology Carver College of Medicine University of Iowa Iowa City IA 3 Tippie College of Business University of Iowa Iowa City IA 4 College of Liberal Arts and Sciences University of Iowa Iowa City IA 5 Redox and Radiation Biology Program Holden Comprehensive Cancer Center University of Iowa Iowa City IA 6 Iowa City VA Healthcare (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundSex?specific differences in vasodilation are mediated in part by differences in cytosolic Ca2+handling, but how variations in mitochondrial Ca2+contributes to this effect remains unknown. Here, we investigated the extent to (...) (Journal of the American Heart Association)
• 12:42
  Survival Probability and Survival Benefit Associated With Primary Prevention Implantable Cardioverter?Defibrillator Generator Changes - Kenneth C. Bilchick, Yongfei Wang , Jeptha P. Curtis , Ramin Shadman , Todd F. Dardas , Inder Anand , Lars H. Lund , Ulf Dahlström , Ulrik Sartipy , and Wayne C. Levy 1 Department of Medicine University of Virginia Health System Charlottesville VA 2 Center for Outcomes Research and Evaluation Yale?New Haven Hospital New Haven CT 3 Department of Internal Medicine Yale University New Haven CT 4 Southern California Permanente Medical Group Los Angeles CT 5 Department of Medicine University of Washington Seattle WA 6 University of Minnesota Minneapolis MN 7 Department of Medicine/Cardiology (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundAs patients derive variable benefit from generator changes (GCs) of implantable cardioverter?defibrillators (ICDs) with an original primary prevention (PP) indication, better predictors of outcomes are needed.Methods and (...) (Journal of the American Heart Association)
• 12:41
  Colchicine Ameliorates Dilated Cardiomyopathy Via SIRT2?Mediated Suppression of NLRP3 Inflammasome Activation - Xuan Sun, Junfeng Duan , Chenyi Gong , Yuting Feng , Jiaxin Hu , Rong Gu , and Biao Xu 1 State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital Medical School of Nanjing University Nanjing China J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundDilated cardiomyopathy remains a leading cause of heart failure worldwide. Immune inflammation response is recognized as a significant player in the progression of heart failure; however, immunomodulatory strategies remain a (...) (Journal of the American Heart Association)
• 12:40
  Hospital?Level Variation in Ticagrelor Use in Patients With Acute Coronary Syndrome - Aya F. Ozaki, Cynthia A. Jackevicius , Alice Chong , Maneesh Sud , Jiming Fang , Peter C. Austin , and Dennis T. Ko 1School of Pharmacy & Pharmaceutical Sciences University of California Irvine CA United States 2College of Pharmacy Western University of Health Sciences Pomona CA United States 3Veterans Affairs Greater Los Angeles Healthcare System Los Angeles CA United States 4ICES Toronto Canada 5University of Toronto Ontario Canada 6Schulich Heart Centre Sunnybrook Health Sciences Centre Toronto Ontario (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundDespite improved outcomes associated with ticagrelor compared with clopidogrel in acute coronary syndrome (ACS), many studies have demonstrated slow adoption of ticagrelor in the United States because of its increased cost. (...) (Journal of the American Heart Association)
• 12:40
  Patent Ductus Arteriosus Stent Versus Surgical Aortopulmonary Shunt for Initial Palliation of Cyanotic Congenital Heart Disease with Ductal?Dependent Pulmonary Blood Flow: A Systematic Review and Meta?Analysis - Stephanie Y. Tseng, Vien T. Truong , Daniel Peck , Sneha Kandi , Samuel Brayer , Don P. Jason , Wojciech Mazur , Garick D. Hill , Awais Ashfaq , Bryan H. Goldstein , and Tarek Alsaied 1 The Heart Center Nationwide Children’s Hospital Columbus OH 2 The Heart Institute, Cincinnati Children’s Hospital Medical Center Cincinnati OH 3 The Christ Hospital Health Network Cincinnati OH 4 Northeast Ohio Medical University Rootstown OH 5 University of Cincinnati College of Medicine Cincinnati OH 6 Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH 7 Heart Institute (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundIn patients with ductal?dependent pulmonary blood flow, initial palliation includes catheter?based patent ductus arteriosus (PDA) stent or surgical aortopulmonary shunt (APS). This meta?analysis aimed to compare outcomes between (...) (Journal of the American Heart Association)
• 12:40
  Mortality Risk in Takotsubo Syndrome Versus Myocarditis - Alan C. Kwan, Jesse Navarrette , Patrick Botting , Melanie T. Chen , Janet Wei , C. Noel Bairey Merz , Joseph E. Ebinger , and Susan Cheng 1Department of Cardiology Barbra Streisand Women's Heart Center Smidt Heart InstituteCedars Sinai Medical Center Los Angeles CA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 12:39
  Multifaceted Intervention to Improve P2Y12 Inhibitor Adherence After Percutaneous Coronary Intervention: A Stepped Wedge Trial - P. Michael Ho, Colin I. O’Donnell , Marina McCreight , Anthony A. Bavry , Hayden B. Bosworth , Saket Girotra , P. Michael Grossman , Christian Helfrich , Faisal Latif , David Lu , Michael Matheny , Kreton Mavromatis , Jose Ortiz , Amitabh Parashar , Devona M. Ratliff , Gary K. Grunwald , Michael Gillette , and Hani Jneid 1 Cardiology Section Rocky Mountain Regional VA Medical Center Aurora CO 2 Department of Medicine University of Colorado School of Medicine Aurora CO 3 Denver?Seattle Center of Innovation for Veteran Centered and Value Driven Care Rocky Mountain Regional VA Medical Center (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundP2Y12 inhibitor medications are critical following percutaneous coronary intervention (PCI); however, adherence remains suboptimal. Our objective was to assess the effectiveness of a multifaceted intervention to improve P2Y12 (...) (Journal of the American Heart Association)

22 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 12:33
  Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart - Keqiang Yan, Zhanlong Mei , Jingjing Zhao , Md Aminul Islam Prodhan , Detlef Obal , Kartik Katragadda , Benjamin Doelling , David Hoetker , Dheeraj Kumar Posa , Liqing He , Xinmin Yin , Jasmit Shah , Jianmin Pan , Shesh Rai , Pawel Konrad Lorkiewicz , Xiang Zhang , Siqi Liu , Aruni Bhatnagar , and Shahid P. Baba 1 Beijing Institute of Genomics Chinese Academy of Sciences, Beishan Industrial Zone Shenzhen China 2 Diabetes and Obesity Center University of Louisville KY 3 Christina Lee Brown Envirome Institute University of Louisville KY USA 4 Department of Chemistry University of Louisville (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundHistidyl dipeptides such as carnosine are present in a micromolar to millimolar range in mammalian hearts. These dipeptides facilitate glycolysis by proton buffering. They form conjugates with reactive aldehydes, such as (...) (Journal of the American Heart Association)
• 12:33
  Exploring Health Care Providers' Experiences of Providing Collaborative Palliative Care for Patients With Advanced Heart Failure At Home: A Qualitative Study - Cassandra Graham, Rebecca Schonnop , Tieghan Killackey , Dio Kavalieratos , Shirley H. Bush , Leah Steinberg , Susanna Mak , Kieran Quinn , and Sarina R. Isenberg 1 Division of Palliative Medicine, Department of Medicine University of Toronto Toronto Canada 2 Division of Palliative Care University Health Network Toronto Canada 3 Department of Emergency Medicine University of Alberta Edmonton Canada 4 Department of Emergency Medicine Royal Alexandra Hospital Edmonton Canada 5 Child Health Evaluative Sciences The Hospital for Sick Children Toronto Canada 6 Division of Palliative Medicine (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe HeartFull Collaborative is a regionally organized model of care which involves specialist palliative care and cardiology health care providers (HCPs) in a collaborative, home?based palliative care approach for patients with (...) (Journal of the American Heart Association)
• 12:33
  Temporal Changes in Beat?to?Beat Variability of Repolarization Predict Imminent Nonsustained Ventricular Tachycardia in Patients With Ischemic and Nonischemic Dilated Cardiomyopathy - Matthew Amoni, Sebastian Ingelaere , Jonathan Moeyersons , Bert Vandenberk , Piet Claus , Robin Lemmens , Sabine Van Huffel , Karin Sipido , Carolina Varon , and Rik Willems 1 Cardiology University Hospitals Leuven Leuven Belgium 2 Experimental Cardiology, Department of Cardiovascular Sciences University of Leuven Belgium 3 STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Department of Electrical Engineering University of Leuven Belgium 4 Imaging and Cardiovascular Dynamics, Department of Cardiovascular Sciences KU Leuven Leuven Belgium 5 Neurology University (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundAn increase in beat?to?beat variability of repolarization (BVR) predicts arrhythmia onset in experimental models, but its clinical translation is not well established. We investigated the temporal changes in BVR before (...) (Journal of the American Heart Association)
• 12:33
  Quantification of Cardiac Adipose Tissue in Failing and Nonfailing Human Myocardium - Kyra K. Peczkowski, Mohammed A. Mashali , Nancy S. Saad , Austin Hare , Courtney M. Campbell , Bryan A. Whitson , Nahush A. Mokadam , and Paul M. L. Janssen 1 Department of Physiology and Cell Biology College of Medicine The Ohio State University Columbus OH 2 Dorothy M. Davis Heart and Lung Research Institute The Ohio State University Columbus OH 3 Department of Internal Medicine College of Medicine The Ohio State University Columbus OH 4 Division of Cardiac Surgery College of Medicine The Ohio State University Columbus (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundBecause body mass index (BMI) is generally used clinically to define obesity and to estimate body adiposity, BMI likely is positively correlated with epicardial adipose tissue (EAT) level. Based on echocardiography, previous (...) (Journal of the American Heart Association)
• 12:32
  Safety and Efficacy of SSRIs in Improving Poststroke Recovery: A Systematic Review and Meta?Analysis - Heba M. Kalbouneh, Ahmad A. Toubasi , Farah H. Albustanji , Yazan Y. Obaid , and Layla M. Al?Harasis 1Department of Anatomy Faculty of Medicine University of Jordan Amman Jordan 2Faculty of Medicine University of Jordan Amman Jordan 3Faculty of Medicine Jordan University of Science and Technology Irbid Jordan J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundSeveral studies investigated the role of selective serotonin reuptake inhibitors (SSRIs) in improving poststroke recovery; thus, we have decided to conduct this systematic review and meta?analysis to investigate the efficacy (...) (Journal of the American Heart Association)
• 12:32
  Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice - Jared M. McLendon, Xiaoming Zhang , Daniel S. Matasic , Mohit Kumar , Olha M. Koval , Isabella M. Grumbach , Sakthivel Sadayappan , Barry London , and Ryan L. Boudreau 1Department of Internal Medicine University of Iowa Carver College of Medicine Iowa City IA 2Abboud Cardiovascular Research Center University of Iowa Carver College of Medicine Iowa City IA 3Department of Molecular Physiology and Biophysics University of Iowa Carver College of Medicine Iowa City IA 4Department of Pharmacology and Systems Physiology University of Cincinnati OH 5Division of Cardiovascular Health and Disease (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundSorbin and SH3 domain containing 2 (Sorbs2) protein is a cytoskeletal adaptor with an emerging role in cardiac biology and disease; yet, its potential relevance to adult?onset cardiomyopathies remains underexplored. Sorbs2 (...) (Journal of the American Heart Association)
• 12:32
  Aspirin Therapy on Prophylactic Anticoagulation for Patients Hospitalized With COVID?19: A Propensity Score?Matched Cohort Analysis of the HOPE?COVID?19 Registry - Francesco Santoro, Ivan J. Núñez?Gil , Enrica Vitale , María C. Viana?Llamas , Rodolfo Romero , Charbel Maroun Eid , Gisela Feltes Guzman , Victor Manuel Becerra?Muñoz , Inmaculada Fernández Rozas , Aitor Uribarri , Emilio Alfonso?Rodriguez , Marcos García Aguado , Jia Huang , Alex Fernando Castro Mejía , Juan Fortunato Garcia Prieto , Javier Elola , Fabrizio Ugo , Enrico Cerrato , Jaime Signes?Costa , Sergio Raposeiras Roubin , Jorge Luis Jativa Mendez , Carolina Espejo Paeres , Alvaro López Masjuan , Francisco Marin , Federico Guerra , Ibrahim El?Battrawy , Bernardo Cortese , Harish Ramakrishna (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundCOVID?19 is an infectious illness, featured by an increased risk of thromboembolism. However, no standard antithrombotic therapy is currently recommended for patients hospitalized with COVID?19. The aim of this study was to (...) (Journal of the American Heart Association)
• 12:32
  Rheumatic Heart Disease Is a Neglected Disease Relative to Its Burden Worldwide: Findings From Global Burden of Disease 2019 - Seyyed?Hadi Ghamari, Mohsen Abbasi?Kangevari , Sahar Saeedi Moghaddam , Arya Aminorroaya , Negar Rezaei , Parnian Shobeiri , Zahra Esfahani , Mohammad?Reza Malekpour , Nazila Rezaei , Ali Ghanbari , Mohammad Keykhaei , Mohammadreza Naderian , Bagher Larijani , Mohamad Taghi Majnoon , Farshad Farzadfar , and Ali H. Mokdad 1Non?Communicable Diseases Research Center Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran Iran 2Tehran Heart CenterTehran University of Medical Sciences Tehran Iran 3Endocrinology and Metabolism Research Center (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundRheumatic heart disease (RHD) takes a heavy toll in low? and middle?income countries. We aimed to present worldwide estimates for the burden of the RHD during 1990 to 2019 using the GBD (Global Burden of Disease) study.Methods (...) (Journal of the American Heart Association)
• 12:31
  Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice - Qing Liang, Hu Xu , Min Liu , Lei Qian , Jin Yan , Guangrui Yang , and Lihong Chen 1Advanced Institute for Medical Sciences Dalian Medical University Dalian China 2School of Bioengineering Dalian University of Technology Dalian China J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundMice with cardiomyocyte?specific deletion of Bmal1, a core clock gene, had spontaneous abnormal cardiac metabolism, dilated cardiomyopathy, and shortened lifespan. However, the role of cardiomyocyte Bmal1 in pressure overload (...) (Journal of the American Heart Association)
• 12:31
  Health State Utility Values in People With Stroke: A Systematic Review and Meta?Analysis - Raed A. Joundi, Joel Adekanye , Alexander A. Leung , Paul Ronksley , Eric E. Smith , Alexander D. Rebchuk , Thalia S. Field , Michael D. Hill , Stephen B. Wilton , and Lauren C. Bresee 1Department of Clinical Neurosciences University of Calgary Alberta Canada 2Division of Neurology Hamilton Health SciencesMcMaster University & Population Health Research Institute Hamilton Ontario Canada 3University of Calgary Calgary Alberta Canada 4University of British Columbia Vancouver British Columbia Canada 5Department of Community Health Sciences University of Calgary Alberta (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundHealth state utility values are commonly used to provide summary measures of health?related quality of life in studies of stroke. Contemporaneous summaries are needed as a benchmark to contextualize future observational studies (...) (Journal of the American Heart Association)
• 12:31
  Racial and Ethnic Differences in Cardiac Rehabilitation Participation: Effect Modification by Household Income - Joshua Garfein, Emily N. Guhl , Gretchen Swabe , Akira Sekikawa , Emma Barinas?Mitchell , Daniel E. Forman , and Jared W. Magnani 1 Department of Medicine University of Pittsburgh School of Medicine Pittsburgh PA 2 Heart and Vascular Institute University of Pittsburgh Medical Center Pittsburgh PA 3 Department of Epidemiology, Graduate School of Public Health University of Pittsburgh PA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundCardiac rehabilitation (CR) is associated with improved cardiovascular outcomes. Racial and ethnic differences in CR have been identified, but whether income may attenuate these disparities remains unknown. We evaluated (1) (...) (Journal of the American Heart Association)
• 12:30
  To Be or Not to Be: Surviving Immune?Mediated Fetal Heart Disease - Edgar Jaeggi, Lisa Hornberger , Bettina Cuneo , Anita J. Moon?Grady , Marie?Josée Raboisson , Jane Lougheed , Karim Diab , Wadi Mawad , and Earl Silverman 1Labatt Family Heart Centre The Hospital for Sick Children Toronto Ontario Canada 2Labatt Family Heart Centre Stollery Children’s Hospital University of Alberta Edmonton Alberta Canada 3Labatt Family Heart Centre Children’s Hospital Colorado Denver CO 4Labatt Family Heart Centre UCSF Benioff Children's Hospital San Francisco CA 5Labatt Family Heart Centre Centre Hospitalier Universitaire Sainte Justine Montréal Quebec Canada 6Labatt Family (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 12:30
  To Be or Not to Be Treated: That Is the Question in Managing a Fetus With Cardiac Injury Exposed to Anti?SSA/Ro - Jill Buyon, Amit Saxena , Deborah Friedman , and Peter Izmirly 1Division of Rheumatology Department of Medicine New York University Grossman School of Medicine New York NY 2Department of Pediatrics New York Medical College Valhalla NY J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 12:30
  Relationship of Sodium Intake With Granulocytes, Renal and Cardiovascular Outcomes in the Prospective EPIC?Norfolk Cohort - Eliane F. E. Wenstedt, Hessel Peters Sengers , S. Matthijs Boekholdt , Kay?Tee Khaw , Nicholas J. Wareham , Bert?Jan H. van den Born , and Liffert Vogt 1Department of Internal Medicine Section of Nephrology Amsterdam UMC University of AmsterdamAmsterdam Cardiovascular Sciences Amsterdam The Netherlands 2Amsterdam UMC University of AmsterdamCenter for Experimental and Molecular Medicine Amsterdam The Netherlands 3Amsterdam UMC The Amsterdam Institute for Infection and Immunity Amsterdam The Netherlands 4Department of Cardiology Amsterdam UMC University of Amsterdam The Netherlands (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundExperimental studies show that high?sodium intake affects the innate immune system, among others with increased circulating granulocytes. Whether this relationship exists on a population level and whether this relates to (...) (Journal of the American Heart Association)
• 12:29
  Arrhythmia Monitoring and Outcomes in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium - Edoardo Bressi, Thomas C. Crawford , Frank M. Bogun , Xiaokui Gu , Kenneth A. Ellenbogen , Alexandra B. Chicos , Henri Roukoz , Peter J. Zimetbaum , Steven J. Kalbfleisch , Francis D. Murgatroyd , David A. Steckman , Lynda E. Rosenfeld , Ann C. Garlitski , Kyoko Soejima , Adarsh K. Bhan , Vasanth Vedantham , Timm M. Dickfeld , David B. De Lurgio , Pyotr G. Platonov , Matthew M. Zipse , Suguru Nishiuchi , Matthew L. Ortman , Calambur Narasimhan , Kris K. Patton , David G. Rosenthal , Siddharth S. Mukerji , Jarieke C. Hoogendoorn , Katja Zeppenfeld , William H. Sauer , Jordana Kron (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. (Journal of the American Heart Association)
• 12:29
  Reliability of Past Medical History in a Single Hospital Participating in Get With The Guidelines?Stroke Registry - Christopher G. Favilla, Alice F. Ford , Ossama Khazaal , Daniel Cristancho , Emily Grodinsky , Judy Dawod , and Scott E. Kasner 1Department of Neurology University of Pennsylvania Philadelphia PA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe GWTG (Get With The Guidelines)?Stroke registry supports clinical research and quality improvement projects that often rely on past medical history elements, the reliability of which remains largely unknown. Here, we (...) (Journal of the American Heart Association)
• 12:29
  Extended Anticoagulation After Pulmonary Embolism: A Multicenter Observational Cohort Analysis - Romain Chopard, Ida Ehlers Albertsen , Fiona Ecarnot , Sebastien Guth , Matthieu Besutti , Nicolas Falvo , Gregory Piazza , and Nicolas Meneveau 1Department of Cardiology University Hospital Jean Minjoz Besançon France 2EA3920 University of Burgundy Franche?Comté Besançon France 3F?CRIN INNOVTE Network Saint?Etienne France 4Aalborg Thrombosis Research Unit Aalborg University Hospital Aalborg Denmark 5Department of Internal Medicine University Hospital Dijon?Bourgogne Dijon France 6Division of Cardiovascular Medicine Department of Medicine Brigham and Women’s HospitalHarvard Medical School (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundPulmonary embolism (PE) has a long?term risk of adverse events, which can be prevented by extended anticoagulation. We compared clinical characteristics and outcomes between patients treated with 2?year extended anticoagulation (...) (Journal of the American Heart Association)
• 12:28
  Increases in Circulating and Fecal Butyrate are Associated With Reduced Blood Pressure and Hypertension: Results From the SPIRIT Trial - Curtis Tilves, Hsin?Chieh Yeh , Nisa Maruthur , Stephen P. Juraschek , Edgar Miller , Karen White , Lawrence J. Appel , and Noel T. Mueller 1Department of Epidemiology Johns Hopkins University Bloomberg School of Public Health Baltimore MD 2Welch Center for Prevention, Epidemiology, and Clinical Research Johns Hopkins University Baltimore MD 3Division of General Medicine and Primary Care Beth Israel Deaconess Medical Center Boston MA J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundShort chain fatty acids (SCFAs) are microbially derived end products of dietary fiber fermentation. The SCFA butyrate reduces blood pressure (BP) in mouse models. The association of SCFAs, including butyrate, with BP in humans (...) (Journal of the American Heart Association)
• 12:28
  Myocardial Injury in Patients With Acute and Subacute Chagas Disease in the Brazilian Amazon Using Cardiovascular Magnetic Resonance - Katia do Nascimento Couceiro, Jessica Vanina Ortiz , Mônica Regina Hosannah da Silva e Silva , Débora Raysa Teixeira de Sousa , Rubens Celso Andrade , Alba Regina Jorge Brandão , Rômulo Freire de Morais , Susan Smith Doria , Rafael Almeida Fonseca , Paula Rita Leite da Silva , Fabio Fernandes , Maria das Graças Vale Barbosa Guerra , Carlos Eduardo Rochitte , João Marcos Bemfica Barbosa Ferreira , and Jorge Augusto de Oliveira Guerra 1Programa de Pós?Graduação em Medicina Tropical–Universidade do Estado do Amazonas Manaus Amazonas Brazil 2Universidade Nilton Lins Manaus Amazonas Brazil 3Instituto do (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundChagas disease is a neglected tropical disease that is still considered a global health emergency. In the Amazon region, most of the reports are of acute cases that are associated with oral transmission. This study aimed to (...) (Journal of the American Heart Association)
• 12:31
  Genetically?Proxied Levels of Vitamin D and Risk of Intracerebral Hemorrhage - Natalia Szejko, Julian N. Acosta , Cameron P. Both , Audrey Leasure , Charles Matouk , Lauren Sansing , Thomas M. Gill , Zhao Hongyu , Kevin Sheth , and Guido J. Falcone 1 Department of Neurology Yale School of Medicine New Haven CT 2 Department of Bioethics Medical University of Warsaw Poland 3 Department of Neurology Medical University of Warsaw Poland 4 Department of Neurosurgery Yale School of Medicine New Haven CT 5 Department of Internal Medicine, Geriatric Medicine Yale School of Medicine New Haven CT 6 Department of Biostatistics Yale School of Public Health New Haven (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundThe evidence linking vitamin D (VitD) levels and spontaneous intracerebral hemorrhage (ICH) remains inconclusive. We tested the hypothesis that lower genetically determined VitD levels are associated with higher risk of (...) (Journal of the American Heart Association)

20 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 12:02
  From Purpose to Impact: Harnessing the Elements to Improve Peripheral Artery Disease Outcomes - Subhash Banerjee, Lawrence Hoang , and Douglas E. Drachman 1University of Texas Southwestern Medical Center Dallas TX 2Methodist Hospital Dallas TX 3Massachusetts General Hospital Boston MA J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
• 12:02
  Cardiovascular and Limb Events Following Endovascular Revascularization Among Patients ?65 Years Old: An American College of Cardiology PVI Registry Analysis - E. Hope Weissler, Yongfei Wang , Jordan M. Gales , Dmitriy N. Feldman , Shipra Arya , Eric A. Secemsky , Herbert D. Aronow , Beau M. Hawkins , J. Antonio Gutierrez , Manesh R. Patel , Jeptha P. Curtis , W. Schuyler Jones , and Rajesh V. Swaminathan 1Division of Vascular and Endovascular Surgery Department of Surgery Duke University School of Medicine Durham NC 2Section of Cardiovascular Medicine Department of Internal Medicine Yale School of Medicine New Haven CT 3Center of Outcome Research and Evaluation Yale?New Haven Health Services New Haven CT 4Texas Heart Institute Houston TX (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundWe aimed to characterize the occurrence of major adverse cardiovascular and limb events (MACE and MALE) among patients with peripheral artery disease (PAD) undergoing peripheral vascular intervention (PVI), (...) (Journal of the American Heart Association)
• 12:01
  Moving Beyond Self?Reported Race in Our Understanding of Cardiovascular Medicine - Nancy Luo 1Sutter Heart and Vascular Institute Sacramento CA J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
• 12:01
  A Frequentist Opting for the Road Less Traveled - Mirvat Alasnag, and Mamas A. Mamas 1Cardiac Center King Fahd Armed Forces Center Jeddah Saudi Arabia 2Keele Cardiovascular Research Group Keele University Stoke on Trent United Kingdom J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
• 12:01
  When the Price Is Right: Beyond the Medical Risks and Benefits of Costly Therapies - Michelle M. Kittleson 1Department of Cardiology Smidt Heart InstituteCedars?Sinai Medical Center Los Angeles CA J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
• 12:01
  Impact of Financial Considerations on Willingness to Take Sacubitril/Valsartan for Heart Failure - Birju R. Rao, Candace D. Speight , Larry A. Allen , Scott D. Halpern , Yi?An Ko , Daniel D. Matlock , Miranda A. Moore , Alanna A. Morris , Laura D. Scherer , Mary C. Thomson , Peter Ubel , and Neal W. Dickert 1Division of Cardiology Department of Medicine Emory University School of Medicine Atlanta GA 2Department of Medicine University of Colorado School of Medicine Aurora CO 3Palliative and Advanced Illness Research (PAIR) Center and Department of Medicine Pennsylvania Perelman School of Medicine Philadelphia PA 4Department of Biostatistics Emory University Rollins School of Public (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundSacubitril/valsartan improves health outcomes for heart failure with reduced ejection fraction relative to angiotensin?converting enzyme inhibitors or angiotensin receptor blockers, but it carries higher (...) (Journal of the American Heart Association)
• 12:00
  Systematic Review and Network Meta?Analysis Comparing Bifurcation Techniques for Percutaneous Coronary Intervention - Dae Yong Park, Seokyung An , Neeraj Jolly , Steve Attanasio , Neha Yadav , Sunil Rao , and Aviral Vij 1Department of Medicine John H. Stroger Jr Hospital of Cook County Chicago IL 2Department of Biomedical Science Seoul National University Graduate School Seoul Korea 3Division of Cardiology Rush University Medical Center Chicago IL 4Division of Cardiology Cook County Health Chicago IL 5Division of Cardiology Rush Medical College Chicago IL 6Duke Clinical Research Institute and Duke University Health System Durham (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundBifurcation lesions account for 20% of all percutaneous coronary interventions and represent a complex subset which are associated with lower procedural success and higher rates of restenosis. The ideal (...) (Journal of the American Heart Association)
• 12:00
  Angiotensin Receptor Neprilysin Inhibition and Associated Outcomes by Race and Ethnicity in Patients With Heart Failure With Reduced Ejection Fraction: Data From CHAMP?HF - Brittany Chapman, Anne S. Hellkamp , Laine E. Thomas , Nancy M. Albert , Javed Butler , J. Herbert Patterson , Adrian F. Hernandez , Fredonia B. Williams , Xian Shen , John A. Spertus , Gregg C. Fonarow , and Adam D. DeVore 1Department of Medicine Duke University School of Medicine Durham NC 2Duke Clinical Research Institute Durham NC 3Cleveland Clinic Cleveland OH 4University of Mississippi Medical Center Jackson MS 5Eshelman School of Pharmacy University of North Carolina Chapel Hill NC 6Mended Hearts Huntsville AL 7Novartis Pharmaceuticals Corporation East Hanover NJ 8Saint Luke’s Mid (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere are limited data on the use of angiotensin receptor neprilysin inhibitors (ARNIs) in minority populations with heart failure (HF) with reduced ejection fraction. We used data from the CHAMP?HF (Change (...) (Journal of the American Heart Association)

17 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 12:55
  Invasive Versus Medical Management in Patients With Chronic Kidney Disease and Non–ST?Segment–Elevation Myocardial Infarction - Monil Majmundar, Gabriel Ibarra , Ashish Kumar , Rajkumar Doshi , Palak Shah , Roxana Mehran , Grant W. Reed , Rishi Puri , Samir R. Kapadia , Sripal Bangalore , and Ankur Kalra 1Department of Cardiology Maimonides Medical Center, Brooklyn New York NY 2Department of Internal Medicine Brown University Providence RI 3Department of Internal Medicine Cleveland Clinic Akron General Akron OH 4Division of Cardiology St. Joseph’s University Medical Center Paterson NJ 5Department of Internal Medicine New York Medical College/Metropolitan Hospital New York NY 6The Zena and Michael A. Wiener (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThe role of invasive management compared with medical management in patients with non–ST?segment–elevation myocardial infarction (NSTEMI) and advanced chronic kidney disease (CKD) is uncertain, given the (...) (Journal of the American Heart Association)
• 12:54
  Invasive Management for Non–ST?Segment–Elevation Myocardial Infarction and Chronic Kidney Disease: Does One Size Fit All? - Ayman Elbadawi, Islam Y. Elgendy , and Paul Kumfa 1 Section of Cardiology Baylor College of Medicine Houston TX 2 Division of Cardiology University of Texas Southwestern Medical Center Dallas TX 3 Division of Cardiovascular Medicine Gill Heart Institute, University of Kentucky Lexington KY 4 Division of Cardiology University of Texas Medical Branch Galveston TX J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)

16 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 14:33
  Trends, Predictors, and Outcomes of Cardiovascular Complications Associated With Polycystic Ovary Syndrome During Delivery Hospitalizations: A National Inpatient Sample Analysis (2002–2019) - Salman Zahid, Muhammad Zia Khan , Smitha Gowda , Nadeen N. Faza , Michael C. Honigberg , Arthur (Jason) Vaught , Carolyn Guan , Anum S. Minhas , and Erin D. Michos 1 Sands?Constellation Heart Institute Rochester General Hospital Rochester NY 2 Division of Cardiovascular Medicine West Virginia University Heart and Vascular Institute Morgantown WV 3 Division of Cardiology Houston Methodist DeBakey Heart and Vascular Center Houston TX 4 Cardiology Division, Department of Medicine Massachusetts General Hospital Boston MA 5 Division of Maternal Fetal Medicine, Department of Gynecology and (...) J Am Heart Assoc
  Journal of the American Heart Association, Ahead of Print. BackgroundWomen with polycystic ovary syndrome (PCOS) have an increased risk of pregnancy?associated complications. However, data on peripartum cardiovascular complications remain limited. Hence, we investigated trends, outcomes, and (...) (Journal of the American Heart Association)

15 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 13:08
  Association of Common and Rare Genetic Variation in the 3?Hydroxy?3?Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk - Jonas Ghouse, Gustav Ahlberg , Anne Guldhammer Skov , Henning Bundgaard , and Morten S. Olesen 1Laboratory for Molecular Cardiology Department of Cardiology Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark 2Laboratory for Molecular Cardiology Department of Biomedical Sciences University of Copenhagen Denmark 3Department of Ophthalmology Copenhagen University HospitalRigshospitalet?GlostrupUniversity of Copenhagen Denmark 4Department of Cardiology Copenhagen University Hospital, RigshospitaletUniversity of Copenhagen (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundResults from animal models and observational studies have raised concerns regarding the potential cataractogenic effects of statin treatment. We investigated whether common and rare genetic variants (...) (Journal of the American Heart Association)

14 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 12:42
  Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out?of?Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry - Ryo Emoto, Mitsuaki Nishikimi , Muhammad Shoaib , Kei Hayashida , Kazuki Nishida , Kazuya Kikutani , Shinichiro Ohshimo , Shigeyuki Matsui , Nobuaki Shime , and Taku Iwami 1 Department of Biostatistics Nagoya University Graduate School of Medicine Nagoya Japan 2 Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan 3 Department of Emergency and Critical Care Medicine Nagoya University Graduate School of Medicine Nagoya Japan 4 Laboratory for Critical Care Physiology The Feinstein Institutes for Medical (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundPredicting a spontaneous rhythm change from nonshockable to shockable before hospital arrival in patients with out?of?hospital cardiac arrest can help emergency medical services develop better strategies for (...) (Journal of the American Heart Association)
• 12:41
  Association of Statins for Primary Prevention of Cardiovascular Diseases With Hospitalization for COVID?19: A Nationwide Matched Population?Based Cohort Study - Kim Bouillon, Bérangère Baricault , Laura Semenzato , Jérémie Botton , Marion Bertrand , Jérôme Drouin , Rosemary Dray?Spira , Alain Weill , and Mahmoud Zureik 1EPI?PHARE Scientific Interest Group in Epidemiology of Health Products Saint?Denis France 2Faculty of Pharmacy Paris?Saclay University Châtenay?Malabry France 3Paris?Saclay University UVSQ CESP?Inserm, Anti?infective evasion and pharmacoepidemiology Montigny le Bretonneux France J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere is little evidence on the relationship between statin use and the risk of hospitalization attributable to COVID?19.Methods and ResultsThe French National Healthcare Data System database was used to (...) (Journal of the American Heart Association)
• 12:41
  Hypertension and Diabetes Status by Patterns of Stress in Older Adults From the US Health and Retirement Study: A Latent Class Analysis - Jessica R. Fernandez, Francisco A. Montiel Ishino , Faustine Williams , Natalie Slopen , and Allana T. Forde 1Division of Intramural Research National Institute on Minority Health and Health DisparitiesNational Institutes of Health Bethesda MD 2Department of Social and Behavioral Sciences Harvard University T. H. Chan School of Public Health Boston MA J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundHypertension and diabetes disproportionately affect older non?Hispanic Black and Hispanic adults in the United States. Chronic stress may partially explain these disparities. This study identified underlying (...) (Journal of the American Heart Association)
• 12:40
  Development and Validation of 3?Year Atrial Fibrillation Prediction Models Using Electronic Health Record With or Without Standardized Electrocardiogram Diagnosis and a Performance Comparison Among Models - Yunjin Yum, Seung Yong Shin , Hakje Yoo , Yong Hyun Kim , Eung Ju Kim , Gregory Y. H. Lip , and Hyung Joon Joo 1 Department of Biostatistics Korea University College of Medicine Seoul Republic of Korea 2 Cardiovascular and Arrhythmia Center Chung?Ang University Hospital Seoul Republic of Korea 3 Korea University Research Institute for Medical Bigdata Science Korea University Seoul Republic of Korea 4 Department of Internal Medicine Korea University Ansan Hospital Seoul Republic of Korea 5 Cardiovascular Center Korea University Guro Hospital Seoul Republic of Korea 6 Liverpool Center for (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundImproved prediction of atrial fibrillation (AF) may allow for earlier interventions for stroke prevention, as well as mortality and morbidity from other AF?related complications. We developed a clinically (...) (Journal of the American Heart Association)
• 12:38
  Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes - Vivien Ngo, Bernd K. Fleischmann , Manfred Jung , Lutz Hein , and Achim Lother 1 Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine University of Freiburg Germany 2 Institute of Physiology I, Life & Brain Center, Medical Faculty University of Bonn Germany 3 Institute of Pharmaceutical Sciences University of Freiburg Germany 4 BIOSS Centre for Biological Signaling Studies University of Freiburg Germany 5 Interdisciplinary Medical Intensive Care (IMIT), Medical Center – University of Freiburg, Faculty of Medicine University of Freiburg (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundEpigenetic modulators have been proposed as promising new drug targets to treat adverse remodeling in heart failure. Here, we evaluated the potential of 4 epigenetic drugs, including the recently developed (...) (Journal of the American Heart Association)
• 12:38
  Association of Race and Ethnicity on the Management of Acute Non?ST?Segment Elevation Myocardial Infarction - Tarryn Tertulien, Stephen T. Broughton , Gretchen Swabe , Utibe R. Essien , and Jared W. Magnani 1 Department of Medicine University of Pittsburgh Medical Center Pittsburgh Pennsylvania 2 Division of Cardiology UPMC Heart and Vascular Institute, University of Pittsburgh Pittsburgh Pennsylvania 3 Center for Health Equity Research and Promotion VA Pittsburgh Healthcare System Pittsburgh Pennsylvania J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundPrior studies have reported disparities by race in the management of acute myocardial infarction (MI), with many studies having limited covariates or now dated. We examined racial and ethnic differences in (...) (Journal of the American Heart Association)
• 12:38
  Interaction Between Race, Ethnicity, Severe Mental Illness, and Cardiovascular Disease - Kevin O'Gallagher, James TH. Teo , Ajay M. Shah , and Fiona Gaughran 1 British Heart Foundation Centre of Research Excellence King’s College London London United Kingdom 2 King’s College Hospital NHS Foundation Trust London United Kingdom 3 Institute of Psychiatry, Psychology and Neuroscience King’s College London London United Kingdom 4 South London and Maudsley NHS Foundation Trust London United Kingdom J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. Severe mental illnesses, such as schizophrenia or bipolar disorder, affect ?1% of the population who, as a group, experience significant disadvantage in terms of physical health and reduced life expectancy. In this (...) (Journal of the American Heart Association)
• 12:37
  Prognostic Value of Exercise Capacity in Kidney Transplant Candidates - Sean Tan, Yi Wen Thang , William R. Mulley , Kevan R. Polkinghorne , Satish Ramkumar , Kevin Cheng , Jasmine Chan , John Galligan , Mark Nolan , Adam J. Brown , Stuart Moir , James D. Cameron , Stephen J. Nicholls , Philip M. Mottram , and Nitesh Nerlekar 1 Monash Cardiovascular Research Centre, Victorian Heart Institute Monash University Melbourne Victoria Australia 2 Monash Heart Monash Health Melbourne Victoria Australia 3 Department of Nephrology Monash Health Melbourne Victoria Australia 4 Department of Medicine Monash University Melbourne Victoria Australia 5 Baker Heart and (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundExercise stress testing for cardiovascular assessment in kidney transplant candidates has been shown to be a feasible alternative to pharmacologic methods. Exercise stress testing allows the additional (...) (Journal of the American Heart Association)
• 12:37
  Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial Cells - Michael Hauke, Robert Eckenstaler , Anne Ripperger , Anna Ender , Heike Braun , and Ralf A. Benndorf 1Department of Clinical Pharmacy and Pharmacotherapy Institute of PharmacyMartin?Luther?University Halle?Wittenberg Halle (Saale) Germany J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThe small GTPase RhoA (Ras homolog gene family, member A) regulates a variety of cellular processes, including cell motility, proliferation, survival, and permeability. In addition, there are reports (...) (Journal of the American Heart Association)
• 12:37
  Effects of Clinical Trial or Research Program Participation Status on In?Hospital Mortality After Transcatheter Aortic Valve Implantation - Tadao Aikawa, Toshiki Kuno , Jef Van den Eynde , Alexandros Briasoulis , and Aaqib H. Malik 1 Department of Cardiology Hokkaido Cardiovascular Hospital Sapporo Japan 2 Department of Radiology Jichi Medical University Saitama Medical Center Saitama Japan 3 Division of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine New York NY 4 Helen B. Taussig Heart Center The Johns Hopkins Hospital and School of Medicine Baltimore MD 5 Department of Cardiovascular Sciences KU Leuven Leuven Belgium 6 Section of Heart Failure and Transplantation, Division of Cardiovascular (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. (Journal of the American Heart Association)
• 12:37
  Moderate? and High?Intensity Exercise Improves Lipoprotein Profile and Cholesterol Efflux Capacity in Healthy Young Men - Kelly M. Stanton, Vivian Kienzle , Donna Lee M. Dinnes , Irina Kotchetkov , Wendy Jessup , Leonard Kritharides , David S. Celermajer , and Kerry?Anne Rye 1Heart Research Institute Sydney New South Wales Australia 2The University of Sydney New South Wales Australia 3Royal Brisbane and Women’s Hospital Herston Queensland Australia 4The ANZAC Research Institute Concord New South Wales Australia 5Royal Prince Alfred Hospital Sydney New South Wales Australia 6The University of New South Wales Sydney New South Wales (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundExercise is associated with a reduced risk of cardiovascular disease. Increased high?density lipoprotein cholesterol (HDL?C) levels are thought to contribute to these benefits, but much of the research in (...) (Journal of the American Heart Association)
• 12:36
  Integrating a Polygenic Risk Score for Coronary Artery Disease as a Risk?Enhancing Factor in the Pooled Cohort Equation: A Cost?Effectiveness Analysis Study - Deo Mujwara, Geoffrey Henno , Stephen T. Vernon , Siyang Peng , Paolo Di Domenico , Brock Schroeder , George B. Busby , Gemma A Figtree , and Giordano Bottà 1Allelica, Inc Wilmington DE 2 Illumina, Inc San Diego CA 3Kolling InstituteRoyal North Shore Hospital Sydney NSW Australia 4Charles Perkins CentreUniversity of Sydney NSW Australia 5Department of Cardiology Royal North Shore Hospital Sydney NSW Australia J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCardiovascular diseases are the leading cause of death in the United States, yet a significant proportion of adults at high risk remain undetected by standard screening practices. Polygenic risk score for (...) (Journal of the American Heart Association)
• 12:36
  Sex?Specific Differences in Clinical Outcomes After Percutaneous Coronary Intervention: Insights from the TAILOR?PCI Trial - Mina Madan, J. Dawn Abbott , Ryan Lennon , Derek Y. F. So , Andrea M. MacDougall , Mary Ann McLaughlin , Vishakantha Murthy , Jacqueline Saw , Charanjit Rihal , Michael E. Farkouh , Naveen L. Pereira , Shaun G. Goodman 1Schulich Heart CentreSunnybrook Health Sciences CentreUniversity of Toronto Toronto Ontario Canada 2Division of Cardiology Lifespan Cardiovascular Institute Warren Alpert Medical School of Brown University Providence RI 3Department of Quantitative Health Sciences Mayo Clinic Rochester MN 4University of Ottawa Heart Institute Ottawa Ontario Canada 5Thunder Bay Regional (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundTAILOR?PCI (Tailored Antiplatelet Initiation to Lessen Outcomes due to decreased Clopidogrel Response After Percutaneous Coronary Intervention) studied genotype?guided selection of antiplatelet therapy after (...) (Journal of the American Heart Association)
• 12:35
  Sex?Based Differences in Outcomes Following Peripheral Artery Revascularization: Insights From VOYAGER PAD - Connie N. Hess, Iris Baumgartner , Sonia S. Anand , Mark R. Nehler , Manesh R. Patel , E. Sebastian Debus , Michael Szarek , Warren Capell , Eva Muehlhofer , Scott D. Berkowitz , Lloyd P. Haskell , Rupert M. Bauersachs , Marc P. Bonaca , and Judith Hsia 1 Division of Cardiology, Department of Medicine University of Colorado School of Medicine Aurora CO 2 CPC Clinical Research Aurora CO 3 Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital University of Bern Switzerland 4 Population Health Research Institute, Hamilton Health Sciences McMaster (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundDespite high female prevalence of peripheral artery disease (PAD), little is known about sex?based outcomes after lower extremity revascularization (LER) for symptomatic PAD. The effects of rivaroxaban (...) (Journal of the American Heart Association)
• 12:35
  Characterization of “ICU?30”: A Binary Composite Outcome for Neonates With Critical Congenital Heart Disease - Monique M. Gardner, Garrett Keim , Jill Hsia , Anh D. Mai , J. William Gaynor , Andrew C. Glatz , and Nadir Yehya 1Division of Cardiac Critical Care Department of Anesthesiology and Critical Care The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of Pennsylvania Philadelphia PA 2Division of Critical Care Department of Anesthesiology and Critical Care The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of Pennsylvania Philadelphia PA 3Division of Cardiology Department of Pediatrics The Children’s Hospital of Philadelphia (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundNeonates with heart disease requiring cardiopulmonary bypass surgery are at high risk for mortality and morbidity. As it is rare, short?term mortality is difficult to use as a primary outcome for clinical (...) (Journal of the American Heart Association)
• 12:34
  Aortic Dimensions Are Larger in Patients With Fibromuscular Dysplasia - Arielle M. Schwartz, Esther Kim , Patrick Gleason , Xiaona Li , Yi?An Ko , and Bryan J Wells 1 Willis Hurst Internal Medicine Residency Program Emory University Atlanta GA 2 Division of Cardiovascular Medicine, Department of Medicine Vanderbilt University Medical Center Nashville NC 3 Division of Cardiology, Department of Medicine Emory University School of Medicine Atlanta GA 4 Department of Biostatistics and Bioinformatics, Rollins School of Public Health Emory University Atlanta (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundFibromuscular dysplasia (FMD) is a disease of unknown etiology that causes stenosis, aneurysmal dilatation, and dissection of vascular beds. Known to affect medium?sized arteries, FMD is not typically (...) (Journal of the American Heart Association)
• 12:34
  Protective Effects of MicroRNA?200b?3p Encapsulated by Mesenchymal Stem Cells–Secreted Extracellular Vesicles in Myocardial Infarction Via Regulating BCL2L11 - Jun Wan, Shaoyan Lin , Zhuo Yu , Zhengkun Song , Xuefeng Lin , Rongning Xu , and Songlin Du 1Department of Cardiovascular Surgery Nanfang Hospital Southern Medical University Guangzhou Guangdong China J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundExtracellular vesicles (EVs) are a popular treatment candidate for myocardial injury. This work investigated the effects of mesenchymal stem cells (MSCs)–secreted EVs–derived miR?200b?3p on cardiomyocyte (...) (Journal of the American Heart Association)
• 12:34
  Systematic Review of Cerebral Phenotypes Associated With Monogenic Cerebral Small?Vessel Disease - Ed Whittaker, Sophie Thrippleton , Liza Y. W. Chong , Victoria G. Collins , Amy C. Ferguson , David E. Henshall , Emily Lancastle , Tim Wilkinson , Blair Wilson , Kirsty Wilson , Cathie Sudlow , Joanna Wardlaw , and Kristiina Rannikmäe 1Medical School University of Edinburgh Edinburgh United Kingdom 2Centre for Medical Informatics Usher Institute University of Edinburgh Edinburgh United Kingdom 3Centre for Clinical Brain Sciences University of Edinburgh Edinburgh United Kingdom 4NHS Greater Glasgow and Clyde Glasgow United Kingdom 5NHS Lothian Edinburgh United Kingdom 6BHF Data Science (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCerebral small?vessel disease (cSVD) is an important cause of stroke and vascular dementia. Most cases are multifactorial, but an emerging minority have a monogenic cause. WhileNOTCH3is the best?known gene, (...) (Journal of the American Heart Association)
• 12:34
  Relative Contribution of Blood Pressure in Childhood, Young? and Mid?Adulthood to Large Artery Stiffness in Mid?Adulthood - Yaxing Meng, Marie?Jeanne Buscot , Markus Juonala , Feitong Wu , Matthew K. Armstrong , Brooklyn J. Fraser , Katja Pahkala , Nina Hutri?Kähönen , Mika Kähönen , Tomi Laitinen , Jorma S. A. Viikari , Olli T. Raitakari , Costan G. Magnussen , and James E. Sharman 1Menzies Institute for Medical ResearchUniversity of Tasmania Hobart Australia 2Department of Medicine University of Turku Turku Finland 3Division of Medicine Turku University Hospital Turku Finland 4Research Centre of Applied and Preventive Cardiovascular Medicine University of Turku Turku Finland 5Centre for Population Health (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundBlood pressure associates with arterial stiffness, but the contribution of blood pressure at different life stages is unclear. We examined the relative contribution of childhood, young? and mid?adulthood (...) (Journal of the American Heart Association)
• 12:33
  Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart Study - Vibhu Parcha, Marguerite R. Irvin , Leslie A. Lange , Nicole D. Armstrong , Akhil Pampana , Mariah Meyer , Suzanne E. Judd , Garima Arora , and Pankaj Arora 1Division of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL 2Department of Epidemiology University of Alabama at Birmingham Birmingham AL 3Division of Biomedical Informatics and Personalized Medicine Department of Medicine University of Colorado School of Medicine Aurora CO 4Department of Epidemiology University of Colorado School of Public Health Aurora CO 5Department of Biostatistics University of Alabama (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCorin enzyme contributes to the processing of inactive natriuretic peptides to bioactive hormones. In Black individuals, Corin gene variants (rs111253292 [Q568P] and rs75770792 [T555I]) have been previously (...) (Journal of the American Heart Association)
• 12:33
  Transcatheter Aortic Valve Implantation With and Without Resheathing and Repositioning: A Systematic Review and Meta?analysis - Francesco Moroni, Lorenzo Azzalini , Lars Sondergaard , Guilherme F. Attizzani , Santiago García , Hani Jneid , Mamas A. Mamas , and Rodrigo Bagur 1Division of Cardiology Pauley Heart CenterVirginia Commonwealth University Richmond VA 2Division of Cardiology Department of Medicine University of Washington Seattle WA 3The Heart Centre, RigshospitaletCopenhagen University Hospital Copenhagen Denmark 4Harrington Heart and Vascular InstituteUniversity Hospitals Cleveland Medical Center Cleveland OH 5The Carl and Edyth Lindner Center for Research and Education, The Christ Hospital Cincinnati OH (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere is a concern that resheathing/repositioning of transcatheter heart valves during transcatheter aortic valve implantation (TAVI) may lead to an increased risk of periprocedural complications. We aimed (...) (Journal of the American Heart Association)
• 12:33
  Altered Cerebral Microstructure in Adults With Atrial Septal Defect and Ventricular Septal Defect Repaired in Childhood - Benjamin Asschenfeldt, Lars Evald , Camilla Salvig , Johan Heiberg , Leif Østergaard , Simon Fristed Eskildsen , and Vibeke Elisabeth Hjortdal 1Department of Cardiothoracic & Vascular Surgery Aarhus University Hospital Denmark 2Center of Functionally Integrative Neuroscience Aarhus University Denmark 3Department of Clinical Medicine Aarhus University Denmark 4Hammel Neurorehabilitation Centre and University Research Clinic Denmark 5Neuroradiology Research Unit, Department of Radiology Aarhus University Hospital Denmark 6Department of Cardiothoracic Surgery, Rigshospitalet and Institute of (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundDelayed brain development, brain injury, and neurodevelopmental disabilities are commonly observed in infants operated for complex congenital heart defect. Our previous findings of poorer neurodevelopmental (...) (Journal of the American Heart Association)
• 12:33
  Low?Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific - Arjen J. Cupido, Folkert W. Asselbergs , A. Floriaan Schmidt , and G. Kees Hovingh 1Department of Vascular Medicine Amsterdam University Medical Centerslocation AMCUniversity of Amsterdam Netherlands 2Department of Cardiology Division of Heart & Lungs University Medical Center UtrechtUtrecht University Utrecht the Netherlands 3Division of Cardiology Department of Medicine University of California, Los Angeles Los Angeles CA 4Faculty of Population Health Sciences Institute of Cardiovascular ScienceUniversity College London London United Kingdom 5Health Data Research UK and Institute of (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundEpidemiological studies show that women are generally at lower risk for cardiovascular disease than men. Here, we investigated the sex?specific differential effect of genetically increased low?density (...) (Journal of the American Heart Association)
• 12:32
  Evaluation of a Population?Wide Mobile Health Physical Activity Program in 696 907 Adults in Singapore - Jiali Yao, Nicole Lim , Jeremy Tan , Andre Matthias Müller , Rob Martinus van Dam , Cynthia Chen , Chuen Seng Tan , and Falk Müller?Riemenschneider 1Saw Swee Hock School of Public Health National University of Singapore Singapore 2Policy, Research and Surveillance Division Health Promotion Board Singapore 3Berlin Institute of HealthCharite University Medical Centre Berlin Germany J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundEvidence of scaled?up physical activity interventions is scarce. This study evaluates the uptake, engagement, and effectiveness of one such intervention program.Methods and ResultsThe program was open to (...) (Journal of the American Heart Association)
• 12:32
  Radiofrequency Catheter Ablation for Pediatric Atrioventricular Nodal Reentrant Tachycardia: Impact of Age on Procedural Methods and Durable Success - Edward T. O’Leary, Jamie Harris , Kimberlee Gauvreau , Courtney Gentry , Audrey Dionne , Dominic J. Abrams , Mark E. Alexander , Vassilios J. Bezzerides , Elizabeth S. DeWitt , John K. Triedman , Edward P. Walsh , and Douglas Y. Mah 1Department of Cardiology Boston Children’s Hospital Boston MA 2Harvard Medical School Boston MA J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundCatheter?based slow?pathway modification (SPM) is the treatment of choice for symptomatic atrioventricular nodal reentrant tachycardia (AVNRT). We sought to investigate the interactions between patient age (...) (Journal of the American Heart Association)
• 12:32
  Association of Familial History of Diabetes, Hypertension, Dyslipidemia, Stroke, or Myocardial Infarction With Risk of Kawasaki Disease - Ji Hee Kwak, Eun Kyo Ha , Ju Hee Kim , Hye Ryung Cha , Seung Won Lee , and Man Yong Han 1Department of Pediatrics Kangbuk Samsung HospitalSungkyunkwan University School of Medicine Seoul Korea 2Department of Pediatrics Kangnam Sacred Heart HospitalHallym University College of Medicine Seoul Korea 3Department of Pediatrics Kangdong Sacred Heart HospitalHallym University College of Medicine Seoul Korea 4Department of Data Science Sejong University College of Software Convergence Seoul Korea 5Department of Precision Medicine Sungkyunkwan University School of Medicine Suwon Korea 6Department (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundThere are few studies on the association with Kawasaki disease in children and the family’s history of cardiovascular disease (CVD). The aim of this study was to identify the association of increased risks (...) (Journal of the American Heart Association)
• 12:32
  Correlation Between Cardiac Images, Biomarkers, and Amyloid Load in Wild?Type Transthyretin Amyloid Cardiomyopathy - Mami Morioka, Seiji Takashio , Naoya Nakashima , Masato Nishi , Akira Fujiyama , Kyoko Hirakawa , Shinsuke Hanatani , Hiroki Usuku , Eiichiro Yamamoto , Masafumi Kidoh , Seitaro Oda , Kenichi Matsushita , Mitsuharu Ueda , and Kenichi Tsujita 1Departments of Cardiovascular Medicine Graduate School of Medical Sciences Kumamoto University Kumamoto Japan 2Departments of Diagnostic Radiology Graduate School of Medical Sciences Kumamoto University Kumamoto Japan 3Departments of Neurology Graduate School of Medical Sciences Kumamoto University Kumamoto (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundSeveral imaging parameters and biomarkers provide diagnostic and prognostic information for wild?type transthyretin amyloid cardiomyopathy. However, the relevance of these parameters and their association (...) (Journal of the American Heart Association)

8 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 13:52
  Underdiagnosis and Undertreatment of Modifiable Cardiovascular Risk Factors Among Survivors of Childhood Cancer - Eric J. Chow, Yan Chen , Gregory T. Armstrong , Laura?Mae Baldwin , Casey R. Cai , Todd M. Gibson , Melissa M. Hudson , Aaron McDonald , Paul C. Nathan , Jeffrey E. Olgin , Karen L. Syrjala , Emily S. Tonorezos , Kevin C. Oeffinger , and Yutaka Yasui 1Public Health Sciences and Clinical Research Divisions Fred Hutchinson Cancer Research Center Seattle WA 2Department of Pediatrics Seattle Children’s HospitalUniversity of Washington Seattle WA 3University of Alberta Edmonton Alberta Canada 4Department of Epidemiology and Cancer Control St. Jude Children’s Research Hospital Memphis TN (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 12, June 21, 2022. BackgroundDetermine the prevalence and predictors associated with underdiagnosis and undertreatment of modifiable cardiovascular disease (CVD) risk factors (hypertension, dyslipidemia, glucose intolerance/diabetes) (...) (Journal of the American Heart Association)

6 June

J Am Heart Assoc https://www.ahajournals.org/feeds.jsp

• 12:04
  Impact of the Obesity Paradox Between Sexes on In?Hospital Mortality in Cardiogenic Shock: A Retrospective Cohort Study - Woochan Kwon, Seung Hun Lee , Jeong Hoon Yang , Ki Hong Choi , Taek Kyu Park , Joo Myung Lee , Young Bin Song , Joo?Yong Hahn , Seung?Hyuk Choi , Chul?Min Ahn , Young?Guk Ko , Cheol Woong Yu , Woo Jin Jang , Hyun?Joong Kim , Sung Uk Kwon , Jin?Ok Jeong , Sang?Don Park , Sungsoo Cho , Jang?Whan Bae , and Hyeon?Cheol Gwon 1Division of Cardiology Department of Medicine Heart Vascular Stroke InstituteSamsung Medical CenterSungkyunkwan University School of Medicine Seoul Republic of Korea 2Division of Cardiology Department of Internal Medicine Chonnam National University Hospital Gwangju (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundSeveral studies have shown that obesity is associated with better outcomes in patients with cardiogenic shock (CS). Although this phenomenon, the “obesity paradox,” reportedly manifests differently based on (...) (Journal of the American Heart Association)
• 12:03
  Is There an Obesity Paradox in Cardiogenic Shock? - Carl J. Lavie, Adrian daSilva?deAbreu , Hector O. Ventura , and Mandeep R. Mehra 1John Ochsner Heart and Vascular InstituteOchsner Clinical School ? The University of Queensland School of Medicine New Orleans LA 2Section of Cardiovascular Medicine Yale School of MedicineHeart and Vascular CenterYale?New Haven Hospital New Haven CT 3Brigham and Women’s Hospital and Harvard Medical School Boston MA J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
• 12:02
  Cardiac Magnetic Resonance Imaging–Based Screening for Cardiac Sarcoidosis in Patients With Atrioventricular Block Requiring Temporary Pacing - Aino?Maija Vuorinen, Jukka Lehtonen , Sami Pakarinen , Miia Holmström , Sari Kivistö , and Touko Kaasalainen 1Radiology HUS Diagnostic CenterUniversity of Helsinki and Helsinki University Hospital Helsinki Finland 2Heart and Lung Center University of Helsinki and Helsinki University Hospital Helsinki Finland 3Haartman HospitalUniversity of Helsinki and Helsinki University Hospital Helsinki Finland J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundSome myocardial diseases, such as cardiac sarcoidosis, predispose to complete atrioventricular block. The European Society of Cardiology Guidelines on cardiac pacing in 2021 recommend myocardial disease (...) (Journal of the American Heart Association)
• 12:02
  Managing Patients With Advanced Atrioventricular Block: The Essential Role of Cardiovascular Magnetic Resonance Imaging for Timely and Accurate Diagnosis - Lisa von Wald, and Chetan Shenoy 1Cardiovascular Division Department of Medicine University of Minnesota Medical School Minneapolis MN J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
• 12:01
  Idiopathic Recurrent Pericarditis: Not Really So Idiopathic? - François Roubille, Clément Delmas , and Camille Roubille 1Cardiology Department INI?CRT PhyMedExp INSERM CNRS CHU de MontpellierUniversité de Montpellier France 2Intensive Cardiac Care Unit Rangueil University Hospital/Institute of Metabolic and Cardiovascular Diseases UMR?1048 National Institute of Health and Medical Research Toulouse France 3Department of Internal Medicine PhyMedExp CHU MontpellierMontpellier University Montpellier France J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
• 12:01
  Pericarditis and Autoinflammation: A Clinical and Genetic Analysis of Patients With Idiopathic Recurrent Pericarditis and Monogenic Autoinflammatory Diseases at a National Referral Center - Claire J. Peet, Dorota Rowczenio , Ebun Omoyinmi , Charalampia Papadopoulou , Bella Ruth R. Mapalo , Michael R. Wood , Francesca Capon , and Helen J. Lachmann 1National Amyloidosis Centre Royal Free London NHS Foundation Trust & Division of Medicine University, College London London United Kingdom 2Department of Medical and Molecular Genetics King’s College London London United Kingdom J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundIdiopathic recurrent pericarditis (IRP) is an orphan disease that carries significant morbidity, partly driven by corticosteroid dependence. Innate immune modulators, colchicine and anti?interleukin?1 agents, (...) (Journal of the American Heart Association)
• 12:00
  Arrhythmogenesis and Prolonged Repolarization From Synthetic Opioids: Finally Sorted? - Lee L. Eckhardt 1Department of Medicine University of Wisconsin?Madison Madison WI J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. (Journal of the American Heart Association)
• 11:59
  Methadone Blockade of Cardiac Inward Rectifier K+ Current Augments Membrane Instability and Amplifies U Waves on Surface ECGs: A Translational Study - Michael G. Klein, Mori J. Krantz , Naheed Fatima , Ashlie Watters , Dayan Colon?Sanchez , Robert M. Geiger , Robert E. Goldstein , Soroosh Solhjoo , Philip S. Mehler , Thomas P. Flagg , and Mark C. Haigney 1Cardiology Division Department of Medicine Uniformed Services University Bethesda MD 2Department of Anatomy, Physiology & Genetics Uniformed Services University Bethesda MD 3Psychiatry Division Outpatient Behavioral Health Services, Denver Health, & University of Colorado School of Medicine Denver CO 4Denver Health Medical Center Cardiology Division Denver CO 5ACUTE at Denver Health (...) J Am Heart Assoc
  Journal of the American Heart Association, Volume 11, Issue 11, June 7, 2022. BackgroundMethadone is associated with a disproportionate risk of sudden death and ventricular tachyarrhythmia despite only modest inhibition of delayed rectifier K+current (IKr),the principal mechanism of (...) (Journal of the American Heart Association)