10:00When Will We Have What We Need to Advise Patients How to Manage Their Carotid Stenosis?: Lessons From SPACE-2 -
Thomas G. Brott James F. Meschia Brajesh K. Lal Ángel Chamorro Virginia J. Howard George Howard Department of Neurology, Mayo Clinic, Jacksonville, FL (T.G.B., J.F.M.). Department of Surgery, University of Maryland, Baltimore (B.K.L.). Department of Neurology, Hospital Clinic, Barcelona, Spain (A.C.). Department of Biostatistics, University of Alabama at Birmingham. (G.H.) Department of Epidemiology, University of Alabama at Birmingham. (V.J.H.)
Stroke
Stroke, Ahead of Print. The recently published SPACE-2 trial (Stent-Supported Percutaneous Angioplasty of the Carotid Artery Versus Endarterectomy-2) compared 3 treatments to prevent stroke in patients with asymptomatic carotid stenosis ?70%: (1) carotid endarterectomy plus best medical (...) (Stroke)
10:00Genetic Susceptibility to Mood Disorders and Risk of Stroke: A Polygenic Risk Score and Mendelian Randomization Study -
Jiangming Sun Yan Borné Andreas Edsfeldt Yunpeng Wang Mengyu Pan Olle Melander Gunnar Engström Isabel Gonçalves Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (J.S., Y.B., A.E., M.P., O.M., G.E., I.G.). Department of Cardiology, Skåne University Hospital, Malmö, Sweden (A.E., I.G.). Wallenberg Center for Molecular Medicine, Lund University, Sweden (A.E.). Lifespan Changes in Bain and Cognition (LCBC), Department of Psychology, University of Oslo, Norway (Y.W., M.P.). Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY., Regeneron Genetics Center Goncalo (...)
Stroke
Stroke, Ahead of Print. BACKGROUND:Mood disorders and strokes are often comorbid, and their health toll worldwide is huge. This study characterizes prognostic and causal roles of mood disorders in stroke.METHODS:We tested if genetic susceptibilities for mood disorders were associated with all (...) (Stroke)
10:00NOTCH2NLC GGC Repeat Expansion in Patients With Vascular Leukoencephalopathy -
Yi-Chu Liao Cheng-Yu Wei Fu-Pang Chang Ying-Tsen Chou Shao-Lun Hsu Chih-Ping Chung Takeshi Mizuguchi Naomichi Matsumoto Shaw-Fang Yet Yi-Chung Lee Departments of Neurology, National Yang Ming Chao Tung University School of Medicine, Taipei, Taiwan. (Y.-C. Liao, Y.-T.C., S.-L.H., C.-P.C., Y.-C. Lee) Department of Pathology and Laboratory Medicine, National Yang Ming Chao Tung University School of Medicine, Taipei, Taiwan. (F.-P.C.) Taipei Veterans General Hospital, Taiwan. Department of Neurology, National Yang Ming Chao Tung University School of Medicine, Taipei, Taiwan. (Y.-C. Liao, (...)
Stroke
Stroke, Ahead of Print. BACKGROUND:Neuronal intranuclear inclusion disease (NIID), caused by GGC (guanine-guanine-cytosine) repeat expansion inNOTCH2NLC, has several clinical and radiological features akin to cerebral small vessel disease (cSVD). The present study tested the hypothesis (...) (Stroke)