11:00Immune Regulation of the Liver Through the PCSK9/CD36 Pathway During Heart Transplant Rejection -
Xi Zhang Heng Xu Jizhang Yu Jikai Cui Zhang Chen Yuan Li Yuqing Niu Song Wang Shuan Ran Yanqiang Zou Jie Wu Jiahong Xia Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan China. (X.Z., H.X., J.Y., J.C., Z.C., Y.L., Y.N., S.W., S.R., Y.Z., J.W., J.X.) Center for Translational Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan China. (X.Z., J.Y., Z.C., Y.L., Y.N., S.W., S.R., J.W., J.X.) Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key (...)
Circulation
Circulation, Ahead of Print. BACKGROUND:PCSK9 (proprotein convertase subtilisin/kexin 9), which is mainly secreted by the liver, is not only a therapeutic target for hyperlipidemia and cardiovascular disease, but also has been implicated in the immune regulation of infections and tumors. (...) (Circulation)