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15 March
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01:00
Various nursing models are usually employed to achieve self-management and improve the quality of life in chronic conditions. Given its person-based characteristics, the 5 A nursing model can improve the quali... -- Research
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The study’s purpose is to explore the link of serum albumin on renal progression in patients with chronic kidney disease (CKD). -- Research
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Impaired renal function was not a recognized indication for renal biopsy. The effects of receiving renal biopsy on the renal functional prognosis for chronic kidney disease (CKD) patients with impaired renal f... -- Research
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Uremic tumoral calcinosis (UTC) is a rare complication in hemodialysis patients, whose mechanism remains incompletely understood. We report two cases with UTC who experienced completely different patterns of r... -- Case Report
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Late-onset oligomeganephronia (OMN) is a rare chronic kidney disease and has no quantitative criteria for diagnosis yet. The current study aimed to explore its clinicopathological features by histomorphometric... -- Research
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Post-operative recurrence of focal segmental glomerulosclerosis according to pre-transplant treatment after kidney transplantation -
Hye Eun Kwon, Young Hoon Kim, Sang Ah Lee, Jae Jun Lee, Youngmin Ko, Sung Shin, Joo Hee Jung, Frances S. Sung, Chung Hee Baek, Hyosang Kim, Su-Kil Park and Hyunwook Kwon
BMC Nephrol
Recurrent focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) is a serious complication and a significant risk factor for graft failure. However, there is no clear evidence of the effec... -- Research
14 March
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01:00
More than 4 billion doses of the Coronavirus disease (COVID-19) vaccine have been administered worldwide but the relationship between the different vaccines and the development of renal disease is unknown. We ... -- Case report
10 March
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01:00
Bevacizumab is a monoclonal antibody drug targeting Vascular Endothelial Growth Factor (VEGF), which binds to VEGF receptors to inhibit vascular endothelial cell proliferation and angiogenesis, thus inhibiting... -- Case report
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Early diagnosis and typing are crucial for improving the prognosis of patients with renal amyloidosis. Currently, Untargeted proteomics based precise diagnosis and typing of amyloid deposits are crucial for gu... -- Research
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People with kidney failure often require surgery and experience worse postoperative outcomes compared to the general population, but existing risk prediction tools have excluded those with kidney failure durin... -- Research
9 March
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01:00
Immune checkpoint inhibitors (ICIs) have provided significant benefits in cancer treatment, but they could develop immune-related adverse events (irAE). ICI-associated renal adverse effects are rare and tubulo... -- Case report
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Chronic kidney disease (CKD) patients with and without heart failure (HF) often present with hyperkalaemia (HK) leading to increased risk of hospitalisations, cardiovascular related events and cardiovascular-r... -- Research
2 March
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01:00
Acute Kidney Injury (AKI) in COVID-19 patients is associated with increased morbidity and mortality. In the present study, we aimed to develop a prognostic score to predict AKI development in these patients. -- Research
27 February
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01:00
Accurate diagnosis and assessment of hematuria is crucial for the early detection of chronic kidney disease(CKD). As instability of urinary RBC count (URBC) often results with clinical uncertainty, therefore n... -- Research
25 February
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01:00
Inflammation plays an important role in the development of acute kidney injury (AKI). However, there are few studies exploring the prognostic influence of C-reactive protein to albumin ratio (CAR) among AKI pa... -- Research article
24 February
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01:00
Study protocol of a randomized controlled trial of fistula vs. graft arteriovenous vascular access in older adults with end-stage kidney disease on hemodialysis: the AV access trial -
Mariana Murea, Ali I. Gardezi, Mathew P. Goldman, Caitlin W. Hicks, Timmy Lee, John P. Middleton, Roman Shingarev, Tushar J. Vachharajani, Karen Woo, Lama M. Abdelnour, Kyla M. Bennett, Duvuru Geetha, Lee Kirksey, Kevin W Southerland, Carlton J. Young, William M. Brown…
BMC Nephrol
Treatment of end-stage kidney disease (ESKD) with hemodialysis requires surgical creation of an arteriovenous (AV) vascular access—fistula (AVF) or graft (AVG)—to avoid (or limit) the use of a central venous c... -- Study Protocol
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Antibody-mediated rejection (AMR) still persists as the major hurdle towards successful renal allograft survival. This paper aims to report on the HLA antibody landscape of renal transplant candidates in Malaysi... -- Research
22 February
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Foetal and early childhood development contributes to the risk of adult non-communicable diseases such as hypertension and cardiovascular disease. We aimed to investigate whether kidney size at birth is associ... -- Research
18 February
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Bosnia and Herzegovina (BiH) and Serbia are countries in the Western Balkans that share parts of their social and political legacy from the former Yugoslavia, such as their health care system and the fact that... -- Research
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Chronic kidney disease (CKD) has been a global public health problem and a major source of suffering and poor quality of life for those afflicted. Using data from the global burden of disease (GBD) study 2019,... -- Research
16 February
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The role of Klotho as a multifunctional protein in anemia is unclear. This study aimed to determine the association between anemia and serum Klotho concentrations in middle-aged and elderly populations. -- Research
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Cardiac valvular calcification (CVC) is prevalent in haemodialysis (HD) patients. Its association with mortality in Chinese incident haemodialysis (IHD) patients remains unknown. -- Research
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More attention has been put on the relationship between pediatric glomerular disease and respiratory tract virus infection. Children with glomerular illness, however, are uncommonly found to have biopsy-proven... -- Research
15 February
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01:00
Assessment of a serum calcification propensity test for the prediction of all-cause mortality among hemodialysis patients -
Adam M Zawada, Melanie Wolf, Abraham Rincon Bello, Rosa Ramos-Sanchez, Sara Hurtado Munoz, Laura Ribera Tello, Josep Mora-Macia, M. Amparo Fernández-Robres, Jordi Soler-Garcia, Josep Aguilera Jover, Francesc Moreso, Stefano Stuard, Manuela Stauss-Grabo, Anke Winter and Bernard Canaud
BMC Nephrol
Vascular calcification is a major contributor to the high cardiac burden among hemodialysis patients. A novel in vitro T50-test, which determines calcification propensity of human serum, may identify patients ... -- Research
14 February
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01:00
Maintenance hemodialysis (MHD) patients often suffer from sarcopenia, which is strongly associated with their long-term mortality. The diagnosis and treatment of sarcopenia, especially possible sarcopenia for ... -- Research
13 February
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Autosomal recessive polycystic kidney disease (ARPKD) is a hereditary condition characterized by massive kidney enlargement and developmental liver defects. Potential consequences during childhood include the ... -- Research
11 February
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01:00
For the improvement of outcome after renal transplantation it is important to predict future risk of major adverse cardiac events as well as all-cause mortality. We aimed to determine the relationship of pre-t... -- Research
9 February
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01:00
One of the rare life-threatening fungal infections is pneumocystis pneumonia (PCP). Immunocompromised patients are the main vulnerable population. We investigate the risk factors associated with the developmen... -- Research
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Tobacco exposure in adults and children with proteinuric glomerulopathies: a NEPTUNE cohort study -
Linda Wang, Bayle Smith-Salzberg, Kevin EC Meyers, Dorey A. Glenn, Katherine R. Tuttle, Vimal K. Derebail, Tammy M. Brady, Keisha Gibson, Abigail R. Smith, Michelle M. O’Shaughnessy, Tarak Srivastava, Gentzon Hall, Jarcy Zee, Markus Bitzer and Christine B. Sethna
BMC Nephrol
Tobacco exposure has been recognized as a risk factor for cardiovascular disease (CVD) and progression of kidney disease. Patients with proteinuric glomerulopathies are at increased risk for cardiovascular mor... -- Research
8 February
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01:00
Galloway-Mowat syndrome (GAMOS) is a group of rare hereditary diseases by the combination of early onset steroid-resistant nephrotic syndrome (SRNS) and microcephaly with brain anomalies caused by WDR73, LAGE3, O... -- Case Report
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Rituximab (RTX) is a standard therapy for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). However, the most frequently used dose may lead to severe adverse effects (SAEs). We explored t... -- Research
7 February
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01:00
Strongyloidiasis is an infectious disease that can be fatal in immunocompromised patients. Patients with end-stage renal failure who are on dialysis have a considerably weakened immune system, and organ transp... -- Research
2 February
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01:00
Serum and plasma levels of Ba, but not those of soluble C5b-9, might be affected by renal function in chronic kidney disease patients -
Ryoko Yamane, Yoshinari Yasuda, Aki Oshima, Yasuhiro Suzuki, Hiroshi Kojima, Hangsoo Kim, Sosuke Fukui, Shoichi Maruyama, Yasuhiko Ito and Masashi Mizuno
BMC Nephrol
During the last few decades, pathogenic mechanisms associated with uncontrolled activation of the complement (C) system and development of anti-C agents have been closely investigated in the field of nephrolog... -- Research article
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Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of hospital-acquired renal failure. However, there is no effective treatment of CI-AKI, and its mechanism is unknown. Interestingly,... -- Research
30 January
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01:00
Macrophages contribute to epithelial–mesenchymal transition (EMT) in diabetic nephropathy (DN). Exosomal long non-coding RNAs (lncRNAs) derived from macrophages play a major role in transmitting biological inf... -- Research
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Globally, the World Health Organization ranks chronic kidney disease (CKD) as one of the top 10 causes of mortality. In South Africa, where noncommunicable diseases have become leading causes of mortality, the... -- Research
26 January
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Kidney failure is rapidly rising in Palestine, as the number of patients receiving maintenance dialysis has quadrupled in the last 15 years. In this study, we share an overview of our experience growing a peri... -- Research
25 January
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Hepcidin is considered to play a central role in the pathophysiology of renal anemia. Recent studies in healthy individuals have demonstrated a suppressive effect of vitamin D (VD) on the expression of hepcidi... -- Research
24 January
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01:00
Immunosuppressive therapy is associated with an increased risk of severe courses of SARS-CoV-2 infection, with frequently delayed viral clearance. We report a case of an acute kidney transplant failure in pers... -- Case Report
19 January
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Hyperkalemia (HK) is a barrier to optimization of renin-angiotensin-aldosterone system inhibitor (RAASi) therapy in heart failure (HF) and chronic kidney disease (CKD). We investigated cardiorenal risk associa... -- Research
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Chronic kidney disease (CKD) is a global challenge. CKD prevalence estimation is central to management strategies and prevention. It is necessary to predict end stage kidney disease (ESKD) and, subsequently, t... -- Research
18 January
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01:00
Ultrasonographic quantitation of quadriceps muscle mass is increasingly used for assessment of sarcopenia, but its relationship with frailty in haemodialysis recipients is not known. This study explores the re... -- Research
17 January
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01:00
Vitamin D deficiency has been examined as a risk factor for severity and progression of kidney disease due to its immunomodulatory effects. There is paucity of data about its impact in IgA nephropathy (IgAN). -- Research
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Electronic alerts (e-alerts) for Acute Kidney Injury (AKI) have been implemented into a variety of different Electronic Health Records (EHR) systems worldwide in order to improve recognition and encourage earl... -- Research
16 January
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01:00
Xanthine oxidase activity has a key role in the development of oxidative stress and progression of cardiovascular diseases. However, the change of xanthine oxidase activity following hemodialysis and its progn... -- Research
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Unfractionated heparin sodium and nafamostat mesylate have long been used as anticoagulants in continuous kidney replacement therapy (CKRT) where citrate is unavailable. This study aimed to determine whether h... -- Research
14 January
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01:00
Hyperlactatemia occurs frequently in critically ill patients, and this pathologic condition leads to worse outcomes in several disease subsets. Herein, we addressed whether hyperlactatemia is associated with t... -- Research
12 January
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01:00
Overt eosinophilic peritonitis (EP) is a relatively uncommon complication of peritoneal dialysis (PD), although not rare. Here we reported a case of EP relieved after changing dialysate. -- Case report
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A survey to gain insight into anticoagulant prescribing practice in the setting of chronic kidney disease (CKD) across the UK was disseminated via renal and haematology networks. Areas of anticoagulant use inc... -- Research
11 January
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01:00
C3 Glomerulopathy (C3G) is a rare glomerular disease caused by dysregulation of the complement pathway. Based on its pathophysiology, treatment with the monoclonal antibody eculizumab targeting complement C5 m... -- Research
10 January
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01:00
Nephrotic syndrome (NS) in children is widely believed to be associated with severe changes in the immune system. Based on lymphocyte subset analysis, we examined the pathogenesis of immune deficiencies in chi... -- Research
9 January
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01:00
The role of higher insulinemic effects of dietary pattern and lifestyle factors on the risk of chronic kidney disease (CKD) is not well-studied. In the current study, we aimed to investigate the relationship b... -- Research
5 January
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01:00
Assessment of fluid removal using ultrasound, bioimpedance and anthropometry in pediatric dialysis: a pilot study -
Abdulla M. Ehlayel, Oluwatimilehin Okunowo, Mohini Dutt, Kathryn Howarth, Babette S. Zemel, Laura Poznick, Xenia Morgan, Michelle R. Denburg, Lawrence Copelovitch, Susan J. Back, Hansel J. Otero and Erum A. Hartung
BMC Nephrol
Fluid overload is associated with morbidity and mortality in children receiving dialysis. Accurate clinical assessment is difficult, and using deuterium oxide (D2O) to measure total body water (TBW) is impractica... -- Research
4 January
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Informal caregivers (i.e. family and friends) provide essential support to people with chronic kidney disease (CKD). Many informal caregivers experience mental health problems such as anxiety and depression du... -- Research
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The prevalence of chronic kidney disease (CKD) is between 10 and 15% worldwide. Ethiopia is seeing a consistent increase in the number of dialysis patients. Patients on chronic hemodialysis have high mortality... -- Research
3 January
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We aimed to investigate the renal prognosis of patients with idiopathic nephrotic syndrome (INS) complicated with steroid-induced diabetes mellitus (SIDM), the association of high-density lipoprotein cholester... -- Research
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The improvement of anaemia over time by erythropoiesis stimulating agent (ESA) is associated with better survival in haemodialysis patients. We previously reported that erythrocyte creatine content, a marker o... -- Research
31 December
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This cross-sectional study aimed to investigate the association between plasma homocysteine (Hcy) and chronic kidney disease (CKD) in US patients with type 2 diabetes mellitus (T2DM). -- Research
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The purpose of this manuscript is to introduce reserve and resilience as novel concepts in chronic kidney disease (CKD) research and present baseline data from a unique prospective cohort study designed to cha... -- Research
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To investigate depression and anxiety and related factors among patients receiving maintenance hemodialysis (MHD). -- Research
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Chronic kidney disease (CKD) is a major risk factor for contrast induced acute kidney injury (CI-AKI) in chronic coronary syndrome (CCS) patients undergoing coronary catheterization. We aimed to evaluate the e... -- Research
30 December
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01:00
Platelet-to-lymphocyte ratio and the first occurrence of peritonitis in peritoneal dialysis patients -
Ning Su, Yijia Zheng, Xing Zhang, Xingming Tang, Li-wen Tang, Qinqin Wang, Xingyu Chen, Xiaoyang Wang, Yueqiang Wen, Xiaoran Feng, Qian Zhou, Jiafan Zhou, Yafang Li and Sijia Shang
BMC Nephrol
Platelet-to-lymphocyte ratio (PLR) has been used as a potential biomarker of inflammation-related diseases, but its role in the peritoneal dialysis-related peritonitis (PDRP) is still uncertain. This study was... -- Research
29 December
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Hemodialysis clinic patient social networks may reinforce positive and negative attitudes towards kidney transplantation. We examined whether a patient’s position within the hemodialysis clinic social network ... -- Research
28 December
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Mesangial proliferative glomerulonephritis (MsPGN) accounts for a main cause of chronic kidney disease (CKD), chronic renal failure and uremia. This paper aimed to examine the effect of Ntrk1 on MsPGN developm... -- Research
27 December
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The current classification for acute kidney injury (AKI) according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria integrates both serum creatinine (SCr) and urine output (UO). Most reports o... -- Research
26 December
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Acidosis frequently occurs in severe acute kidney injury (AKI), and continuous renal replacement therapy (CRRT) can control this pathologic condition. Nevertheless, acidosis may be aggravated; thus, monitoring... -- Research
24 December
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Fluid assessment is challenging, and fluid overload poses a significant problem among dialysis patients, with pulmonary oedema being the most serious consequence. Our study aims to develop a simple objective f... -- Research
23 December
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Chronic kidney disease (CKD) is linked to high morbidity and mortality and increased hospitalization burden. If appropriately managed in the outpatient setting, ambulatory care-sensitive conditions (ACSCs) do ... -- Research
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Peritonitis is one of the major complications of peritoneal dialysis. The most common cause of peritonitis is infection at the catheter exit site. This study aimed to determine the effect of propolis on the in... -- Research
21 December
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01:00
In recent years, it has been reported that diabetic patients tend to have a lower zinc intake due to unbalanced diet accompanying changes in lifestyle habits. We investigated serum zinc concentration in diabet... -- Research
20 December
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Introducing a de-novo home haemodialysis (HHD) program often raises safety concerns as errors could potentially lead to serious adverse events. Despite the complexity of performing haemodialysis at home withou... -- Research
19 December
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01:00
Acute kidney injury (AKI) is independently associated with morbidity and mortality in a wide range of surgical settings. Nowadays, with the increasing use of electronic health records (EHR), advances in patien... -- Research
16 December
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Peritonitis is the most common complication in patients undergoing peritoneal dialysis (PD). Most patients recover with appropriate antibiotic treatment; however, when peritonitis repeatedly relapses, the caus... -- Case report
27 July
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02:00
Currently, there is a lack of clinical indicators that can accurately distinguish diabetic kidney disease (DKD) from non-diabetic kidney disease (NDKD) in type 2 diabetes. The purpose of this study was to inve... -- Research
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There are few studies on immunoglobulin A nephropathy (IgAN) at high altitude. This study aimed to analyze the clinical and pathological characteristics of IgAN between Tibet and Beijing, which provided a basi... -- Research
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The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a multicentre prospective double-blind randomised controlled trial -
Sharlene A. Greenwood, Nicholas Beckley-Hoelscher, Elham Asgari, Salma Ayis, Luke A. Baker, Debasish Banerjee, Sunil Bhandari, Kate Bramham, Joseph Chilcot, James Burton, Philip A. Kalra, Courtney J. Lightfoot, Kieran McCafferty, Thomas H. Mercer, Darlington O. Okonko, Benjamin Oliveira…
BMC Nephrol
Many people living with chronic kidney disease (CKD) are iron deficient, even though they may not be anaemic. The Iron and Muscle study aims to evaluate whether iron supplementation reduces symptoms of fatigue... -- Research
26 July
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02:00
Gitelman syndrome (GS) is a rare autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we report, for the first time, a case of GS overlapping nephrotic syndrome (NS) related to PLA2R-associated m... -- Case report
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Good knowledge and early identification of chronic kidney disease (CKD) can help in preventing disease progression in its early stages and reducing undesired outcomes. The aim of the current study was to asses... -- Research
25 July
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02:00
Percutaneous kidney biopsies are important tools for the diagnosis of kidney diseases. Nephrologists must be familiar with the expected complications of the procedure to provide an adequate informed consent. H... -- Research
23 July
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02:00
Glomerular endotheliosis is the pathognomonic glomerular lesion in pre-eclampsia that has also been described in those taking tyrosine kinase inhibitors for cancer treatment. Ibrutinib is a Bruton’s tyrosine k... -- Case report
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Residual kidney function (RKF) may provide many benefits to patients on permanent renal replacement therapy that are reflected in better control of biochemical parameters. In hemodialysis patients, quality of ... -- Research
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TAFRO syndrome is an acute or subacute systemic inflammatory disease with no apparent cause, presenting with fever, generalized edema, thrombocytopenia, renal damage, anemia, and organ enlargement. Interleukin... -- Case report
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Chronic kidney disease (CKD) affects gastrointestinal system (GIS) and causes histological, functional and mucosal changes. There are scarce data investigating GIS symptoms and findings in patients with CKD st... -- Research
22 July
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02:00
Living with frailty and haemodialysis: a qualitative study -
Hannah M. L. Young, Nicki Ruddock, Mary Harrison, Samantha Goodliffe, Courtney J. Lightfoot, Juliette Mayes, Andrew C. Nixon, Sharlene A. Greenwood, Simon Conroy, Sally J. Singh, James O. Burton, Alice C. Smith and Helen Eborall
BMC Nephrol
Frailty is highly prevalent in people receiving haemodialysis (HD) and is associated with poor outcomes. Understanding the lived experiences of this group is essential to inform holistic care delivery. -- Research
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02:00
Gut microbiota dysbiosis in patients with chronic kidney disease on haemodialysis (CKD-HD) creates an increase in proteolytic bacteria activity, leading to an increase in the production of uraemic toxins, such... -- Research
21 July
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02:00
Given the complexity and variety in treatment options for advanced chronic kidney disease (CKD), shared decision-making (SDM) can be a challenge. SDM is needed for making decisions that best suit patients’ nee... -- Research
20 July
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To evaluate the presence of LGA and the relationship with the 10-year risk of a cardiovascular event in hypertensive and diabetic patients in Primary Health Care. -- Research
18 July
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The inflammatory bowel disease, containing Crohn’s disease and ulcerative colitis, was rare in the population, especially in the complication of kidney disease. A few studies had found proteinuria played a pot... -- Research
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To investigate the relationship between serum uric acid levels and glomerular ischemic lesions in patients with immunoglobulin A nephropathy (IgAN) and the relevant risk factors. -- Research
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Human Kidney Injury Molecule-1, also known as HAVCR-1 (Hepatitis A virus cellular receptor 1), belongs to the cell-surface protein of immunoglobulin superfamily involved in the phagocytosis by acting as scaven... -- Research
16 July
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02:00
Alport syndrome is a hereditary kidney disease characterized by hematuria and proteinuria. Although there have been reports of autosomal dominant COL4A4 variants, this is likely an underdiagnosed condition. Impro... -- Case report
15 July
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Hispanic Americans receive disproportionately fewer organ transplants than non-Hispanic whites. In 2018, the Hispanic Kidney Transplant Program (HKTP) was established as at the University of Colorado Hospital ... -- Research
14 July
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02:00
Glomerulopathy with fibronectin deposits (GFND) is a rare autosomal dominant genetic disorder, and proteinuria and hematuria are the most common clinical manifestations. The pathogenesis of this disease is pri... -- Case report
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Recently, early graft loss has become very rare in living-related kidney transplantation (LKT) as a result of decreased risk of hyperacute rejection and improvements in immunosuppressive regimens. Post-transpl... -- Case report
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Distal renal tubular acidosis (dRTA) is the most common type of renal tubular acidosis (RTA) in children. Pediatric dRTA is usually genetic and rarely occurs due to acquired issues such as obstructive uropathi... -- Case report
13 July
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02:00
The clinical and pathological impact factors for renal function recovery in acute kidney injury (AKI) on the progression of renal function in primary membranous nephropathy (PMN) with AKI patients have not yet... -- Research
11 July
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02:00
Over half of the patients with hepatitis B virus associated membranous nephropathy (HBV-MN) were found to be phospholipase A2 receptor (PLA2R) positive. Whether MN is really secondary to hepatitis B or just co... -- Research
9 July
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02:00
Hyperphosphatemia is common in patients on peritoneal dialysis (PD). Restricting dietary phosphorus often leads to a decrease in protein intake, which may result in hypoalbuminemia. The high pill burden of pho... -- Research
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The high burden of chronic kidney disease in First Nations peoples requires urgent attention. Empowering people to self-manage their own condition is key, along with promotion of traditional knowledge and empo... -- Research
8 July
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02:00
Lupus nephritis (LN) is a common and serious complication of systemic lupus erythematosus (SLE). However, the aetiology and pathogenesis of LN remain unknown. 1,25-dihydroxyvitamin D3 [1,25-(OH)2-VitD3] is the... -- Research
7 July
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02:00
Despite estimated glomerular filtration rate (eGFR) being the best marker for kidney function, there are no studies in sub-Saharan Africa comparing the performance of various equations used to determine eGFR. ... -- Research
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COVID-19 infection is considered to cause high mortality in kidney transplant recipients (KTR). Old age, comorbidities and acute kidney injury are known risk factors for increased mortality in KTR. Nevertheles... -- Research
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The clinical trajectory for patients with primary membranous nephropathy ranges widely from spontaneous remission to a rapid decline in kidney function. Etiologies for rapid progression with membranous nephrop... -- Case report
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Page kidney (PK) is the occurrence of kidney hypoperfusion and ischemia due to pressure on the kidney by a subcapsular hematoma (SH), a mass, or fluid collection. SH after renal transplantation may result in k... -- Case report
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High prevalence of chronic kidney disease of unknown etiology among workers in the Mesoamerican Nephropathy Occupational Study -
Sinead A. Keogh, Jessica H. Leibler, Caryn M. Sennett Decker, Juan Jose Amador Velázquez, Emmanuel R. Jarquin, Damaris Lopez-Pilarte, Ramon Garcia-Trabanino, Iris S. Delgado, Zoe E. Petropoulos, David J. Friedman, Magaly Rosario Amador Sánchez, Raul Guevara, Michael D. McClean, Daniel R. Brooks and Madeleine K. Scammell
BMC Nephrol
Mortality from chronic kidney disease of unknown etiology (CKDu) is extremely high along the Pacific coast of Central America, particularly among sugarcane workers. The Mesoamerican Nephropathy Occupational St... -- Research
6 July
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02:00
Development of an online patient decision aid for kidney failure treatment modality decisions -
Noel Engels, Paul B. van der Nat, Jet W. Ankersmid, Janine C. M. Prick, Ellen Parent, Regina The, Asako Takahashi, Hans A. J. Bart, Cornelia F. van Uden-Kraan, Anne M. Stiggelbout, Willem J. W. Bos and Marinus A. van den Dorpel
BMC Nephrol
Patient decision aids (PtDAs) support patients and clinicians in shared decision-making (SDM). Real-world outcome information may improve patients’ risk perception, and help patients make decisions congruent w... -- Research
4 July
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02:00
Lupus nephritis is a common manifestation of Systemic Lupus Erythematosus. Mycophenolate is recommended by guidelines for induction therapy in patients with proliferative lupus nephritis and nephrotic range pr... -- Research
1 July
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02:00
The all-cause mortality of patients undergoing hemodialysis (HD) is higher than in the general population. The first 6 months after dialysis are important for new patients. The aim of this study was to develop... -- Research
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02:00
Investigating the effect of metabolic disorders on chronic kidney disease (CKD) in the presence or the absence of obesity is of great importance. This study aimed to examine the independent and joint relations... -- Research
29 June
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02:00
Patients on maintenance hemodialysis (HD) exhibit a high risk of death, cardiovascular and cerebrovascular diseases (CCDs). Previous studies indicated complement activation associated with the increased risk o... -- Research
28 June
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02:00
Serum total indoxyl sulfate levels and all-cause and cardiovascular mortality in maintenance hemodialysis patients: a prospective cohort study -
Qian Li, Shuang Zhang, Qi-Jun Wu, Jia Xiao, Zhi-Hong Wang, Xiang-Wei Mu, Yu Zhang, Xue-Na Wang, Lian-Lian You, Sheng-Nan Wang, Jia-Ni Song, Xiu-Nan Zhao, Zhen-Zhen Wang, Xin-Yi Yan, Yu-Xin Jin, Bo-Wen Jiang…
BMC Nephrol
The association between serum total indoxyl sulfate (tIS), and cardiovascular disease (CVD) and all-cause mortality is a matter of debate. In the current study we sought to determine the association, if any, b... -- Research
27 June
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02:00
Engagement in exercise by haemodialysis (HD) patients has been shown to generate benefits both in terms of improved functional capacity and in the health-related quality of life. The use of non-immersive virtu... -- Research
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02:00
First-year mortality in incident dialysis patients: results of the Peridialysis study -
James Heaf, Maija Heiro, Aivars Petersons, Baiba Vernere, Johan V. Povlsen, Anette Bagger Sørensen, Naomi Clyne, Inga Bumblyte, Alanta Zilinskiene, Else Randers, Niels Løkkegaard, Mai Rosenberg, Stig Kjellevold, Jan Dominik Kampmann, Björn Rogland, Inger Lagreid…
BMC Nephrol
Controversy surrounds which factors are important for predicting early mortality after dialysis initiation (DI). We investigated associations of predialysis course and circumstances affecting planning and exec... -- Research
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02:00
Arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome is a rare disease with a high mortality rate caused by VPS33B or VIPAS39 mutations. ARC syndrome typically presents with arthrogryposis, renal tubula... -- Case report
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02:00
Nephrolithiasis is not common in children, but the incidence is gradually increased in these years. Urinary tract malformations, urinary infection, dietary habits, geographic region and genetic factor are invo... -- Research
25 June
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02:00
Kidney biopsy is the most vital tool guiding a nephrologist in diagnosis and treatment of kidney disease. Over the last few years, we have seen an increasing number of kidney biopsies being performed by interv... -- Research
24 June
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02:00
Clinical practice guidelines recommend specialist referral according to different criteria. The aim was to assess recommended and observed referral rate and health care expenditure according to recommendations... -- Research
23 June
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02:00
The study aimed to investigate the incidence and risk factors of acute kidney injury (AKI) in elderly patients (aged ? 75 years) undergoing major nonvascular abdominal surgery. -- Research
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02:00
Asymptomatic hyperuricemia was found to be associated with increased cardiovascular disease risk but the potential benefits of urate-lowering therapy (ULT) remain controversial. We conducted a systematic revie... -- Research
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02:00
Chronic renal failure can lead to dialysis and/or a kidney transplant in the final stage. The number of patients under dialysis has increased considerably in the world and particularly in sub-Saharan Africa. Dial... -- Research
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02:00
The purpose of this study is to present the prevalence and effects of direct arterial puncture (DAP) for hemodialysis patients, and to introduce optimal option for the vascular access (VA) in certain hemodialy... -- Research
21 June
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02:00
In end-stage kidney disease, patients may undergo parathyroidectomy if secondary hyperparathyroidism cannot be managed medically. This study was designed to estimate the parathyroidectomy rate in the United St... -- Research
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02:00
Prediction of graft survival for Kidney Transplantation (KT) is considered a risky task due to the scarcity of donating organs and the use of health care resources. The present study aimed to design and evalua... -- Software
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02:00
The vascular access preservation and the maintenance of a complication-free fistula remains an Achilles’ heel of hemodialysis in chronic kidney patients due to its substantial contribution to the morbidity and... -- Study protocol
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02:00
Most patients on peritoneal dialysis (PD) in the United States choose automated PD via cyclers. Cyclers have evolved considerably over time with older versions (e.g. HomeChoice Pro) replaced by more sophistica... -- Research
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02:00
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination has become a major part of the strategy to reduce Coronavirus disease 2019 (COVID-19) numbers worldwide. To date, vaccinations based on ... -- Case report
20 June
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02:00
Chemokine (C–C motif) receptor 2 (CCR2) is involved in important physiological and pathological processes, such as inflammation and autoimmune diseases. Abnormal immune and inflammatory responses play a critic... -- Research
17 June
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02:00
Lupus nephritis (LN) is the most common severe complication of systemic lupus erythematosus (SLE) which results in high morbidity and mortality. Up to 60% of adult patients with SLE develop the renal disease w... -- Research
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02:00
CKD-associated pruritus (chronic kidney disease-associated pruritus) is one of the common symptoms in hemodialysis patients, with a major effect on sleep quality because it occurs at night. The main objective ... -- Research
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02:00
Elevated parathyroid hormone one year after kidney transplantation is an independent risk factor for graft loss even without hypercalcemia -
Manabu Okada, Yoshihiro Tominaga, Tetsuhiko Sato, Toshihide Tomosugi, Kenta Futamura, Takahisa Hiramitsu, Toshihiro Ichimori, Norihiko Goto, Shunji Narumi, Takaaki Kobayashi, Kazuharu Uchida and Yoshihiko Watarai
BMC Nephrol
Hypercalcemic hyperparathyroidism has been associated with poor outcomes after kidney transplantation (KTx). However, the clinical implications of normocalcemic hyperparathyroidism after KTx are unclear. This ... -- Research
16 June
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02:00
T-type calcium channels (TTCC) are low voltage activated channels that are widely expressed in the heart, smooth muscle and neurons. They are known to impact on cell cycle progression in cancer and smooth musc... -- Research
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02:00
Atherosclerotic renovascular disease (ARVD) often follows an asymptomatic chronic course which may be undetected for many years. However, there are certain critical acute presentations associated with ARVD and... -- Case report
14 June
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02:00
Stage 5 chronic kidney disease (CKD) patients often experience decisional conflict when faced with the selection between the initiation of dialysis and conservative care. The study examined the effects of a br... -- Research article
13 June
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02:00
Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality and morbidity associated with DKD are increasing with the global prevalence of type 2 diabetes. Chronic, sub-clinical, ... -- Review
11 June
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02:00
Technique failure is more likely to occur during the first 12 months after peritoneal dialysis (PD) initiation, which is a great challenge encountered in PD patients. The aim of this study was to investigate t... -- Research
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02:00
Perioperative hemoglobin drop after noncardiac surgery is associated with acute kidney injury (AKI). However, opinion on the tolerable difference in postoperative hemoglobin drop in patients with different pre... -- Research
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02:00
Progression of chronic kidney disease (CKD) may be delayed if patients engage in healthy lifestyle behaviors. However, lifestyle adherence is very difficult and may be influenced by problems in psychosocial fu... -- Research
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02:00
Central fibrous area in the glomerular vascular pole consists of fibrous collagens and is associated with advanced age: a cross-sectional study -
Satoshi Hara, Yutaka Yamaguchi, Takeshi Zoshima, Ichiro Mizushima, Kazunori Yamada, Ryo Inoue, Hisao Muto, Kazuaki Mizutomi, Masayoshi Hirata, Hideo Araki, Ryoichi Miyazaki and Mitsuhiro Kawano
BMC Nephrol
For the optimal management of patients with both allograft kidneys and native kidney diseases, the recognition of the histological features associated with older age is important. This is because most patholog... -- Research
9 June
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02:00
Chronic kidney disease (CKD) is one of the major global causes of mortality, described as the most neglected chronic disease. This study aimed to determine the prevalence and determinants of CKD in the setting... -- Research
3 June
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02:00
In critically ill patients, acute pain occurs frequently, causes sympathetic activation, release of inflammatory mediators, and potential organ dysfunction, with the kidneys potentially sensitive to inflammati... -- Research article
1 June
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02:00
Qualitative patient interviews and patient-reported outcome instruments are important tools to understand the patient experience of disease. The aim of this study was to use patient interviews to identify conc... -- Research
31 May
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02:00
Left ventricular hypertrophy (LVH) is common among patients undergoing dialysis. However, the dynamic structural changes of LV are rarely discussed. The study aimed to investigate the prognostic significance o... -- Research
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02:00
SARS-COV-2 vaccine responses in renal patient populations -
Rona M. Smith, Daniel J. Cooper, Rainer Doffinger, Hannah Stacey, Abdulrahman Al-Mohammad, Ian Goodfellow, Stephen Baker, Sara Lear, Myra Hosmilo, Nicholas Pritchard, Nicholas Torpey, David Jayne, Vivien Yiu, Anil Chalisey, Jacinta Lee, Enric Vilnar…
BMC Nephrol
Dialysis patients and immunosuppressed renal patients are at increased risk of COVID-19 and were excluded from vaccine trials. We conducted a prospective multicentre study to assess SARS-CoV-2 vaccine antibody... -- Research
28 May
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02:00
Pyrethroids are used for insect control. They act on voltage-gated sodium channels in neurons. Lambdacyhalothrin (LCH) is a type II pyrethroid producing choreoatetosis and salivation in rodents. Vascular endot... -- Research
26 May
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02:00
Serum leptin level and incidence of CKD: a longitudinal study of adult enrolled in the Korean genome and epidemiology study(KoGES) -
Yon Chul Park, Solam Lee, Young-Sang Kim, Jae-Min Park, Kunhee Han, Hunju Lee, Kyung-Won Hong, Jong-Koo Kim, Eun Suk Cho, Tae-Ha Chung, Bom-Taeck Kim and Sang Baek Koh
BMC Nephrol
Chronic kidney disease(CKD) is a major public health issue and is highly prevalent in the general population. Leptin is an adipose tissue-derived endocrine factor that has been associated with several metaboli... -- Research article
25 May
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02:00
Kidney diseases constitute an important proportion of the non-communicable disease (NCD) burden in Sub-Saharan Africa (SSA), though prevention, diagnosis and treatment of kidney diseases are less prioritized i... -- Research
24 May
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02:00
To explore the biological variation (BV) of kidney injury markers in serum and urine of healthy subjects within 24 hours to assist with interpretation of future studies using these biomarkers in the context of... -- Research
23 May
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02:00
First case of a renal cyst infection caused by Desulfovibrio: a case report and literature review -
Yoshiki Okamoto, Yoei Miyabe, Momoko Seki, Yusuke Ushio, Keisuke Sato, Eri Kasama, Kenichi Akiyama, Kazunori Karasawa, Keiko Uchida, Ken Kikuchi, Kosaku Nitta, Takahito Moriyama and Junichi Hoshino
BMC Nephrol
Genus Desulfovibrio species is a sulphate-reducing anaerobic gram-negative rod that resides in the human oral cavity and intestinal tract. It was reported as the causative pathogen of bacteraemia and abdominal in... -- Case report
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02:00
Despite the high economic and mortality burden of chronic kidney disease, studies on survival and predictors of mortality among patients on hemodialysis in Ethiopia especially in the Amhara region are scarce c... -- Research
21 May
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02:00
Hyperphosphatemia (HP) is associated with vascular calcification (VC) in chronic kidney disease (CKD). However, relationship between HP-induced-endothelial extracellular vesicles (HP-EC-EVs) and VC is unclear,... -- Research
19 May
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02:00
Syndrome of inappropriate antidiuretic hormone secretion is associated with different proton pump inhibitor use: a pharmacovigilance study -
Mengmeng Wang, Lingjian Zhang, Min Jia, Junyan Wang, Zhiwen Shen, Shuyue Wang, Xinghui Zhang, Jing Xu, Zheng Zheng, Xuanrui Lv, Xiaoyu Zong, Hui Li, Jin Zhou, Tong Meng, Mingzhu Chen, Bin Zhao…
BMC Nephrol
The objective of this study was to evaluate the reported associations between the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and a variety of proton pump inhibitors (PPI) through analysis... -- Research
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02:00
Assisted home hemodialysis is a therapeutic modality for patients diagnosed with end-stage renal disease who require dialysis replacement therapy and have concomitant health limitations that prevent them from ... -- Research
18 May
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02:00
The mortality rate associated with coronavirus disease 2019 (COVID-19) is high among haemodialyzed patients. We sought to describe the serological status of haemodialysis patients having received up to three d... -- Research
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02:00
Association of acute kidney disease with the prognosis of ischemic stroke in the Third China National Stroke Registry -
Yilun Zhou, Dongxue Wang, Hao Li, Yuesong Pan, Xianglong Xiang, Yu Wu, Xuewei Xie, Xianwei Wang, Yang Luo, Xia Meng, Jinxi Lin, Hong Wang, Yong Huo, Kunihiro Matsushita, Jing Chen, Fan Fan Hou…
BMC Nephrol
Acute kidney disease (AKD) evolves a spectrum of acute and subacute kidney disease requiring a global strategy to address. The present study aimed to explore the impact of AKD on the prognosis of ischemic stroke. -- Research
17 May
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02:00
Patients who are HLA-sensitized are at high risk for early antibody-mediated rejection (AMR) and worse outcomes. Therefore, it is crucial to detect the presence of donor-specific antibodies (DSAs) using pretra... -- Case report
16 May
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02:00
Patients on hemodialysis often suffer from reduced muscle strength and exercise capacity due to the decreased quantity and quality of muscle. Cumulative studies showed ultrasound echo intensity (EI) had great ... -- Research
14 May
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02:00
To explore the technical specifications and clinical outcomes of thrombosed aneurysmal haemodialysis arteriovenous fistula (AVF) treated with ultrasound-guided percutaneous transluminal angioplasty combined wi... -- Research
13 May
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02:00
Statins therapy has been primarily recommended for the prevention of cardiovascular risk in patients with chronic kidney diseases. Statins has also been proved some benefits in lipid-induced kidney diseases. T... -- Research
12 May
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02:00
COVID-19 in Kidney Transplant Recipients: A Multicenter Experience from the First Two Waves of Pandemic -
Erol Demir, Zuhal Atan Ucar, Hamad Dheir, Ramazan Danis, Berna Yelken, Murathan Uyar, Ergun Parmaksiz, Ayse Serra Artan, Ayse Sinangil, Ozgur Merhametsiz, Serap Yadigar, Ahmet Burak Dirim, Baris Akin, Nurana Garayeva, Seda Safak and Aydin Turkmen
BMC Nephrol
Kidney transplant recipients have an increased risk of complications from COVID-19. However, data on the risk of allograft damage or death in kidney transplant recipients recovering from COVID-19 is limited. I... -- Research
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02:00
Dent disease is an X-linked disorder characterized by low molecular weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and chronic kidney disease (CKD). It is caused by mutations in the chloride voltag... -- Case report
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02:00
Bartonella endocarditis is often a diagnostic challenge due to its variable clinical manifestations, especially when it is first presented with involvement of organs other than skin and lymph nodes, such as t... -- Case report
11 May
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02:00
Hyponatraemia is a documented but under-recognised cause of rhabdomyolysis, with the contrasting treatment strategies for the two conditions posing a unique challenge. Balancing the need for aggressive fluid r... -- Case report
10 May
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02:00
Tripterygium Wilfordii Hook F (TwHF) preparation has been widely used in the treatments of IgA nephropathy (IgAN) in China. However, the effectiveness and safety of the new generation of TwHF preparation, KuxX... -- Research
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02:00
Recurrence of IgA nephropathy (IgAN) after kidney transplantation occurs in about 30% of patients. The relevance of recurrence for the long-term graft survival is expected to increase, since graft survival con... -- Research
6 May
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02:00
Elderly hemodialysis patients have a higher rate of mortality than nonelderly hemodialysis patients. Recent studies shown that the serum uric acid to creatinine ratio (SUA/Scr) was associated with all-cause mo... -- Research
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02:00
The coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produced a pandemic since March 2020 by affecting more than 243 million people with more than 5 mil... -- Study protocol
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02:00
Coronavirus disease 2019 (COVID-19) is identified as the pneumonia and acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The intravascular thrombotic ph... -- Case report
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02:00
Metformin-associated lactic acidosis (MALA) is a rare but life-threatening condition. Here, we report the outcome of a patient with MALA complicated by acute coronary syndrome. -- Case report
5 May
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02:00
This study aims to evaluate the impact of multidisciplinary pre-dialysis care (MDPC) on the risks of peritonitis, technique failure and mortality in peritoneal dialysis (PD) patients. -- Research
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02:00
The dysfunction of RNA binding proteins (RBPs) is associated with various inflammation and cancer. The occurrence and progression of tumors are closely related to the abnormal expression of RBPs. There are few... -- Research
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02:00
Tunnel exposure, a non-infectious complication, is a rare finding in peritoneal dialysis (PD) patients, which has been described in some case reports. Our study aimed to present catheter salvage therapy using ... -- Research
4 May
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02:00
Gitelman Syndrome (GS) is a hereditary tubulopathy associated with a biallelic inactivating mutations of the SLC12A3 gene encoding the thiazide-sensitive sodium-chloride cotransporter (NCCT). The typical clinical... -- Case report
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02:00
Prevalence of Fabry disease amongst Chronic Kidney Disease (CKD) patients on haemodialysis has been shown to be approximately 0.2%. -- Research
2 May
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02:00
The burden of both acute kidney injury and chronic kidney disease is on the rise globally. In sierra Leone, there has been no data on renal patients or admissions. This study intends to close this gap in knowl... -- Research
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02:00
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been shown to exert cardiorenal protective effects in diabetic patients and are widely used clinically. In addition, an increasing number of reports now s... -- Case report
30 April
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02:00
Optimal management of anemia of chronic kidney disease (CKD) remains controversial. This retrospective study aimed to describe the epidemiology and selected clinical outcomes of anemia in patients with CKD in ... -- Research
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02:00
A diagnosis of chronic kidney disease has been strongly associated with cardiovascular disease and mortality in a number of studies, but the association with specific causes of death has not been assessed in d... -- Research
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02:00
The prevalence of idiopathic membranous nephropathy (IMN) is increasing worldwide and the gut microbiota is recognized to play a role in its pathology. The aim of this study was to understand the involvement o... -- Research
29 April
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02:00
To date, nephrotic syndrome (NS) has not been well characterized in patients with IgA nephropathy (IgAN). Whether decline in serum albumin is an ominous sign in IgAN patients with massive proteinuria remains u... -- Research
28 April
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02:00
The progression of chronic kidney disease (CKD) is associated with an increasing risk of cardiovascular morbidity and mortality due to elevated serum phosphate levels. Besides low phosphate diets and hemodialy... -- Research
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02:00
Diabetic nephropathy is the leading cause of kidney failure. Clinical practice guidelines recommend prescribing renin–angiotensin aldosterone system inhibitors (RAASi) to prevent diabetic nephropathy at any st... -- Research
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02:00
Post-transplant malignancy is major morbidity complicated in kidney transplantation (KT). In Korea, a few studies have investigated the sex- and age-dependent risk for post-transplant malignancy among KT recip... -- Research
27 April
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02:00
Markers of kidney function, genetic variation related to cognitive function, and cognitive performance in the UK Biobank -
Erin L. Richard, Linda K. McEvoy, Ian J. Deary, Gail Davies, Steven Y. Cao, Eyal Oren, John E. Alcaraz, Andrea Z. LaCroix, Jan Bressler and Rany M. Salem
BMC Nephrol
Chronic kidney disease has been linked to worse cognition. However, this association may be dependent on the marker of kidney function used, and studies assessing modification by genetics are lacking. This stu... -- Research
22 April
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02:00
Therapeutic strategies, including dietary intervention, to target non-dialysis dependent Chronic Kidney Disease (CKD) progression have been at the forefront of recent renal research. Nephrologists and other re... -- Research
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02:00
Hyperuricemia and diabetes mellitus (DM) are associated with increased mortality risk in patients with chronic kidney disease (CKD). Here we aimed to evaluate the independent and joint risks of these two condi... -- Research
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02:00
Association of plasma neutrophil gelatinase-associated lipocalin and thoracic aorta calcification in maintenance hemodialysis patients with and without diabetes -
Kai Wei, Gesheng Song, Linhe Xi, Juan Chen, Chuancai Sun, Ping Chen, Yong Wei, Li Wang, Xianglei Kong, Yang Li, Dongmei Xu and Xiaoyan Jia
BMC Nephrol
Neutrophil gelatinase-associated lipocalin (NGAL) is not only a bone-derived factor involved in metabolism, but also a biomarker of kidney disease and cardiovascular pathophysiology. We conducted this cross-se... -- Research article
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02:00
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) may coexist with rheumatoid arthritis (RA). However, it is unclear whether the manifestations of AAV with and without coexisting RA are s... -- Research article
19 April
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02:00
There is controversy regarding the impact of delayed graft function (DGF) on kidney transplant outcomes. We hypothesize that the duration of DGF, rather than DGF itself, is associated with long-term kidney gra... -- Research
18 April
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02:00
Steroid pulse (SP) therapy is one of the immunosuppressive therapies for immunoglobulin A nephropathy (IgAN). Although there are various protocols of SP therapy in IgAN, the intermittent SP (ISP) and consecuti... -- Research
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02:00
Diabetic nephropathy (DN) is the major cause of kidney failure, and glomerular podocytes play critical roles in the pathogenesis of DN by maintaining the glomerular structure and filtration barrier. Klotho and... -- Research article
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02:00
Sunitinib-induced high-grade proteinuria and irreversible renal allograft dysfunction are rare conditions. Here, we present a patient who had received renal allograft and later developed metastatic clear cell ... -- Case report
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02:00
Eosinophilic peritonitis is a well-known complication at the initiation of peritoneal dialysis. It is often due to an allergic reaction to peritoneal dialysis solution or sometimes to the peritoneal dialysis c... -- Case report
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02:00
Acute and chronic kidney diseases are important comorbidities in People Living With HIV (PLWH). Biopsy is often pursued in this cohort with ongoing renal impairment without a clear aetiology, in order to estab... -- Research
15 April
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02:00
This report introduces an unusual cause of kidney failure in a previously healthy pediatric patient. She developed thrombotic microangiopathy (TMA) that was diagnosed post-partum, requiring dialysis and eculiz... -- Case report
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02:00
Renal perfusion may redistribute from cortex to medulla during systemic hypovolaemia and after renal ischaemia for other reasons, but there is no consensus on this matter. We studied renal perfusion after rena... -- Research article
14 April
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02:00
Comparing prevalence of chronic kidney disease and its risk factors between population-based surveys in Russia and Norway -
Sarah Cook, Marit D. Solbu, Anne Elise Eggen, Olena Iakunchykova, Maria Averina, Laila A. Hopstock, Kamila Kholmatova, Alexander V. Kudryavtsev, David A. Leon, Sofia Malyutina, Andrew Ryabikov, Elizabeth Williamson and Dorothea Nitsch
BMC Nephrol
Little data exists on the prevalence of chronic kidney disease (CKD) in the Russian population. We aimed to estimate the prevalence of CKD in a population-based study in Russia, compare with a similar study in... -- Research
13 April
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02:00
Systemic amyloidosis is classified according to the deposited amyloid fibril protein (AFP), which determines its best therapeutic scheme. The most common type of AFP found are immunoglobulin light chains. The ... -- Research
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02:00
IgA nephropathy (IgAN), which has been reported as the most prevalent glomerulonephritis globally, is the major contributor to end-stage renal diseases. This bioinformatics study aimed to explore glomerulotubu... -- Research
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02:00
Chronic kidney disease effects about 4.2 million people in Poland, yet Polish organ donation research is rare. In addition, compared to other countries in the world, Poland has a relatively low living donation... -- Research
12 April
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02:00
Among the possible causes of hypertension in adolescence, electrolyte imbalances and environmental pollutants are drawing increasing attention. We aimed to examine the relationship between bisphenol A (BPA), p... -- Research
11 April
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02:00
Acute kidney injury (AKI) can lead to chronic kidney disease, which results in poor long-term outcomes. There is plausibility that increased levels of physical activity may promote renal recovery post-AKI. Thi... -- Research
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02:00
Minimal change disease (MCD) is a common cause of the nephrotic syndrome. Several studies have shown an increased incidence of cancer in patients with MCD. However, there are no reports on the association betw... -- Case report
9 April
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02:00
Adherence of patients with End-Stage Renal Disease (ESRD) to Hemodialysis (HD), prescribed medications, diet and fluid restrictions is essential to get the desirable outcome and prevent complications. During C... -- Research
7 April
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02:00
Survivors of critical illness and acute kidney injury (AKI) are at risk of increased morbidity. The purpose of this study was to compare physical, emotional, and cognitive health in survivors of critical illne... -- Research
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02:00
Aplastic anemia (AA) is a rare but fatal disorder characterized by pancytopenia due to bone marrow hypoplasia. Anti-glomerular basement membrane disease (anti-GBM disease) is an immune complex small-vessel vas... -- Case report
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02:00
The flare of immune-mediated disease following coronavirus disease of 2019 (COVID-19) vaccination is a rare adverse event following immunization. De novo, as well as relapsing IgA nephropathy (IgAN) cases, hav... -- Case report
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02:00
Membranous Nephropathy (MN) is a common cause of nephrotic syndrome (NS) in adults. Recognition of MN as an antibody mediated autoimmune disease has enabled the introduction of anti-B-cell therapy. Rituximab, ... -- Case report
6 April
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02:00
According to dietary recommendations, reduction of sodium intake has potential to reduce Chronic Kidney Disease (CKD) risk; however the role of dietary potassium and the sodium -to- potassium ratio in the deve... -- Research
5 April
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02:00
In the light of recent years, an increase in the number of life-threatening infections due to various fungi has been observed, especially in tertiary care centres. With Amphotericin B labelled as the first cho... -- Research
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02:00
Up to 60% of pediatric renal transplant recipients with end-stage renal disease due to primary focal and segmental glomerulosclerosis (FSGS) may develop recurrent disease. Such recurrence is associated with po... -- Research
4 April
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02:00
Correlation between intestinal flora disruption and protein–energy wasting in patients with end-stage renal disease -
Jianguang Hu, Xiaoshi Zhong, Yan Liu, Jing Yan, Daoyuan Zhou, Danping Qin, Xiao Xiao, Yuanyuan Zheng, Luona Wen, Rongshao Tan, Pan Liang and Yun Liu
BMC Nephrol
Different dialysis treatments may affect the composition and structure of the intestinal flora of dialysis-treated chronic kidney disease (CKD) patients. This study aimed to analyze the correlations between th... -- Research
2 April
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02:00
Aortic valve stenosis (AS) has a high prevalence and poor prognosis in patients who receive maintenance dialysis. However, few large-scale observational studies in Japan have investigated patients with AS who ... -- Research
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02:00
Nephrotic syndrome (NS) results in massive proteinuria and hypoalbuminemia, which are responsible for a compensatory increase in protein synthesis in the liver. Serum cholinesterase (ChE) also increases in NS.... -- Research
31 March
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02:00
Published literatures on repeat renal biopsy of AL amyloidosis have basically reached a consensus that amyloid material deposit does not disappear or diminish after satisfactory hematologic response, regardles... -- Case report
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02:00
Depressive symptoms, fatigue, and poor sleep quality are associated with renal function deterioration in patients with nondialysis chronic kidney disease (CKD-ND). This study was designed to examine whether fa... -- Research
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02:00
Although cisplatin-based chemotherapy is a standard treatment for urothelial carcinoma, it often causes acute kidney injury (AKI). AKI and dysfunction are observed in 25–35% of cisplatin-based chemotherapy pat... -- Research
30 March
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02:00
Nuclear receptor-binding SET domain protein 2 (NSD2) is a histone methyltransferase that has been demonstrated to regulate insulin secretion and glucose concentration. This study focused on the role of NSD2 in... -- Research
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02:00
Circulating Proprotein Convertase Subtilisin/Kexin type 9 level independently predicts incident cardiovascular events and all-cause mortality in hemodialysis black Africans patients -
François-Pantaléon Musungayi Kajingulu, François Bompeka Lepira, Aliocha Natuhoyila Nkodila, Jean-Robert Rissassy Makulo, Vieux Momeme Mokoli, Pepe Mfutu Ekulu, Justine Busanga Bukabau, Yannick Mayamba Nlandu, Augustin Luzayadio Longo, Nazaire Mangani Nseka, Laura Labriola and Ernest Kiswaya Sumaili
BMC Nephrol
Cardiovascular (CV) disease is the leading cause of mortality in patients with end-stage kidney disease (ESKD). The aim of the present study was to determine whether Proprotein Convertase Subtilisin/Kexin type... -- Research
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02:00
Incidence and cost of haemolytic uraemic syndrome in urban China: a national population-based analysis -
Jingnan Feng, Ke Xu, Xinmiao Shi, Lu Xu, Lili Liu, Fang Wang, Xuhui Zhong, Guozhen Liu, Jinxi Wang, Pei Gao, Jie Ding, Shengfeng Wang and Siyan Zhan
BMC Nephrol
Haemolytic uraemic syndrome (HUS) is a severe syndrome that causes a substantial burden for patients and their families and is the leading cause of acute kidney injury in children. However, data on the epidemi... -- Research
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02:00
Informed dialysis selection and greater home dialysis use are the two long-desired, underachieved targets of advanced chronic kidney disease (CKD) care in the US healthcare system. Observational institutional ... -- Research
25 March
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01:00
Chronic kidney disease (CKD) affects 8 to 16% of the world’s population and is one of the top ten important drivers of increasing disease burden. Apart from genetic predisposition, lifestyle factors greatly co... -- Research
24 March
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01:00
Determining factors of functioning in hemodialysis patients using the international classification of functioning, disability and health -
Luciana M. M. Santos, Pedro Henrique S. Figueiredo, Ana C. R. Silva, Patrícia C. Campos, Gabriele T. Gonçalves, Jaqueline de Paula C Freitas, Fidelis Antônio da Silva Junior, Jousielle Márcia Santos, Frederico L. Alves, Vanessa G. B. Rodrigues, Emílio Henrique B. Maciel, Maria Cecília S. M. Prates, Borja Sañudo, Redha Taiar, Mario Bernardo-Filho, Vanessa P. Lima…
BMC Nephrol
Hemodialysis (HD) treatment affects functioning, physical activity level, clinical biomarkers, and body composition. However, the association between these variables with functioning, considering International... -- Research article
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01:00
IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated... -- Research
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01:00
Regulation of SARS CoV-2 host factors in the kidney and heart in rats with 5/6 nephrectomy—effects of salt, ARB, DPP4 inhibitor and SGLT2 blocker -
Yingquan Xiong, Denis Delic, Shufei Zeng, Xin Chen, Chang Chu, Ahmed A. Hasan, Bernhard K. Krämer, Thomas Klein, Lianghong Yin and Berthold Hocher
BMC Nephrol
Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstr... -- Research
23 March
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01:00
Data on the long-term effects of neonatal acute kidney injury (AKI) are limited. -- Research
22 March
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01:00
Studies have revealed that patients with chronic kidney disease (CKD) have dietary patterns different from those of the general population. However, no studies have compared the dietary patterns of between pat... -- Research
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