02:00
A novel inhibitor of Factor XIa as potential haemostasis-sparing anticoagulant for patients with atrial fibrillation Eur Heart J

Comment on ‘Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study’ which was presented at the American College of Cardiology (ACC) 2022 (...)

7 May

Eur Heart J https://academic.oup.com/site_5375/

02:00
The risk of ‘hidden’ sodium and of low vitamin D levels - Crea F. Eur Heart J

6 May

Eur Heart J https://academic.oup.com/site_5375/

02:00
Detection of risk factors in childhood: a new perspective in cardiovascular prevention - Volpe M, Galiuto L. Eur Heart J

Comment on “Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events” which was published in the New England Journal of Medicine, https://doi.org/10.1056/NEJMoa2109191.

5 May

Eur Heart J https://academic.oup.com/site_5375/

02:00
The European Heart Journal: fulfilling the mission - Crea F, Badimon L, Berry C, et al. Eur Heart J

AbstractIn September 2020, the new Editors of the European Heart Journal (EHJ) wrote the following in their inaugural editorial: “The fundamental mission of the Journal remains the reduction of the global burden of cardiovascular disease. We aspire to advance this aim by worldwide teamwork to (...)

3 May

Eur Heart J https://academic.oup.com/site_5375/

02:00
A call to embrace a culture of openness in cardiovascular research - Cobey K, Liu P. Eur Heart J

If we have learned anything as a biomedical research community in the past 2 years because of the COVID-19 pandemic, it is that there are major unaddressed challenges and inefficiencies in how research is traditionally conducted and disseminated. This ‘inefficiency’ in biomedical research has (...)

1 May

Eur Heart J https://academic.oup.com/site_5375/

02:00
Valvular heart disease: the quest for new pharmacological targets - Crea F. Eur Heart J

28 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Corrigendum to: Targeting the CCL2–CCR2 axis for atheroprotection Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehac094.

25 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
The PACMAN-AMI trial: game over for the “vulnerable plaque”? - Vergallo R, Patrono C. Eur Heart J

Comment on the article ‘Effect of alirocumab added to high-intensity statin therapy on coronary atherosclerosis in patients with acute myocardial infarction: the PACMAN-AMI randomized clinical trial’, published in JAMA, doi:10.1001/jama.2022.5218.
02:00
Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study - Eckhardt C, Balte P, Barr R, et al. Eur Heart J

AbstractAimsThe aim is to evaluate associations of lung function impairment with risk of incident heart failure (HF).Methods and resultsData were pooled across eight US population-based cohorts that enrolled participants from 1987 to 2004. Participants with self-reported baseline cardiovascular (...)
02:00
HFp2EF: heart failure with pulmonary dysfunction and preserved ejection fraction? - Maron B, Humbert M. Eur Heart J

22 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Left main revascularization: an evidence-based reconciliation Eur Heart J
02:00
Stereotactic radioablation to treat ventricular tachycardia related to a left ventricular mass - Ninni S, Longere B, Mirabel X. Eur Heart J
02:00
Infectious endarteritis associated with patent ductus arteriosus and vegetation: a challenging diagnosis and treatment - Ku L, Cheng Y, Ma X. Eur Heart J
02:00
The end of aspirin for dementia prevention in diabetes? - Kristensen S, Olesen K, Maeng M. Eur Heart J

20 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
How delivering cardiopulmonary resuscitation and basic life support skills training through places of worship can help save lives and address health inequalities - Khanji M, Waqar S, Khawaja Z, et al. Eur Heart J
02:00
Data standards for heart failure: the European Unified Registries for Heart Care Evaluation and Randomized Trials (EuroHeart) - Aktaa S, Batra G, Cleland J, et al. Eur Heart J

AbstractStandardized data definitions are essential for assessing the quality of care and patient outcomes in observational studies and randomized controlled trials. The European Unified Registries for Heart Care Evaluation and Randomized Trials (EuroHeart) project of the European Society of (...)
02:00
Heart transplantation: focus on donor recovery strategies, left ventricular assist devices, and novel therapies - Crespo-Leiro M, Costanzo M, Gustafsson F, et al. Eur Heart J

AbstractHeart transplantation is advocated in selected patients with advanced heart failure in the absence of contraindications. Principal challenges in heart transplantation centre around an insufficient and underutilized donor organ pool, the need to individualize titration of (...)
02:00
A deleterious interaction between omecamtiv mecarbil and atrial fibrillation in patients with heart failure: an influence of digoxin? - van der Meer P, Rienstra M, van Veldhuisen D. Eur Heart J
02:00
Heart failure with normal natriuretic peptide levels: more fat, and that is the main problem - Verbrugge F, Borlaug B. Eur Heart J

This commentary refers to ‘Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality’, by F.H. Verbrugge et al., https://doi.org/10.1093/eurheartj/ehab911 and the discussion piece ‘Mixing the fat with (...)
02:00
Mixing the fat with water: are normal natriuretic peptide heart failure with preserved ejection fraction patients just more obese? - Olivella A, Méndez A, Ferreira-González I. Eur Heart J

This commentary refers to ‘Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality’, by F.H. Verbrugge et al., https://doi.org/10.1093/eurheartj/ehab911 and the discussion piece ‘Heart failure with (...)

19 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
In vivo generated chimeric antigen receptor T cells reduce fibrosis and restore cardiac function in experimental heart failure - Liuzzo G, Patrono C. Eur Heart J

Comment on ‘CAR T cells produced in vivo to treat cardiac injury’ published in Science (https://doi.org/10.1126/science.abm0594).

14 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Fighting against sudden cardiac death: the new frontiers - Crea F. Eur Heart J

13 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
The importance of time-to-event analysis in measuring the prognostic impact of coronary flow reserve - Kelshiker M, Seligman H, Howard J, et al. Eur Heart J

This commentary refers to ‘Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis’, by M.A. Kelshiker et al., https://doi.org/10.1093/eurheartj/ehab775 and the discussion piece ‘An attempt to better show some results such as the comparison of mortality and major (...)
02:00
An attempt to better show some results such as the comparison of mortality and major adverse cardiovascular events between the abnormal and normal coronary flow reserve cohorts - Zhu H, Chen T, Huang J. Eur Heart J

This commentary refers to ‘Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis’, by M.A. Kelshiker et al., https://doi.org/10.1093/eurheartj/ehab775 and the discussion piece ‘The importance of time-to-event analysis in measuring the prognostic impact of (...)
02:00
Hospitalization for heart failure: a window of opportunity - Wachter R, Rommel K. Eur Heart J
02:00
Increased risk of incident diabetes in patients with long COVID - Paneni F, Patrono C. Eur Heart J

Comment on ‘Risks and burdens of incident diabetes in long COVID: a cohort study’ which was published in Lancet Diabetes Endocrinol (https://doi.org/10.1016/S2213-8587(22)00044-4).
02:00
Pointing a FINGER at the contribution of lifestyle to cardiovascular events and dementia - Noutsias M, Hauptmann M, Völler H. Eur Heart J
02:00
The DISCHARGE trial: imaging a new strategy for the clinical management of stable chest pain? - Vergallo R, Volpe M. Eur Heart J

Comment on the article ‘CT or invasive coronary angiography in stable chest pain’, published in the New England Journal of Medicine (https://doi.org/10.1056/NEJMoa2200963).

11 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Age at first syncope: a consideration for assessing probable cause? - Colburn S, Benditt DG. Eur Heart J

8 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Master switches in cardiac ischaemia: the Collaborative Research Center (CRC) 1116 of the German Research Foundation Eur Heart J

German Research Foundation10.13039/501100001659
02:00
Corrigendum to: P2Y12 inhibitor adherence trajectories in patients with acute coronary syndrome undergoing percutaneous coronary intervention: prognostic implications Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehac116.
02:00
Global disparities in prescription of guideline-recommended drugs for heart failure with reduced ejection fraction - Tromp J, Ouwerkerk W, Teng T, et al. Eur Heart J

AbstractBackgroundHeart failure (HF) is a global challenge, with lower- and middle-income countries (LMICs) carrying a large share of the burden. Treatment for HF with reduced ejection fraction (HFrEF) improves survival but is often underused. Economic factors might have an important effect on (...)
02:00
Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial - Parish S, Mafham M, Offer A, et al. Eur Heart J

AbstractAimsAspirin is widely used in cardiovascular disease prevention but is also associated with an increased risk of bleeding. The net effect of aspirin on dementia and cognitive impairment is uncertain.Methods and resultsIn the ASCEND trial, 15 480 people from the UK with diabetes and no (...)

7 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Transcatheter closure of a rare ruptured giant non-coronary Valsalva sinus aneurysm - Shen Q, Deng X, Jing C, et al. Eur Heart J

A 40-year-old male patient was admitted to hospital due to paroxysmal palpitations in the recent 2 months. Heart auscultation found continuous murmurs and electrocardiogram monitoring showed frequent short ventricular tachycardia. Computed tomography angiography revealed that a giant aneurysm (...)
02:00
Double aortic arch with aortic arch diverticulum leading to the use of tracheal intubation in a newborn - Zhu J, Zou J, Zhu S, et al. Eur Heart J
02:00
Soluble LOX-1 levels during acute coronary syndrome: a potent and multifaceted warning sign for cardiovascular risk - Sposito A. Eur Heart J
02:00
Twitter promotion is associated with higher citation rates of cardiovascular articles: the ESC Journals Randomized Study - Ladeiras-Lopes R, Vidal-Perez R, Santos-Ferreira D, et al. Eur Heart J

AbstractThe association between the dissemination of scientific articles on Twitter and online visibility (as assessed by the Altmetric Score) is still controversial, and the impact on citation rates has never been rigorously addressed for cardiovascular medicine journals using a randomized (...)

6 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Cardiac cell therapy: a call for action Eur Heart J
02:00
Attentive follow-up to counter alarmism - Twerenbold R, Cavus E, Blankenberg S. Eur Heart J

This commentary refers to ‘Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme’ by E.L. Petersen et al., https://doi.org/10.1093/eurheartj/ehab914 and the discussion piece ‘Alarmist reporting on the pandemic: time (...)
02:00
Alarmist reporting on the pandemic: time to say no! - Roy A. Eur Heart J

This commentary refers to ‘Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme’ by E.L. Petersen et al., https://doi.org/10.1093/eurheartj/ehab914 and the discussion piece ‘Attentive follow-up to counter alarmism’ (...)
02:00
Is there an increased incidence of subclinical proximal deep vein thrombosis after mild to moderate course of SARS-CoV-2 infection? - Müller L, Mendoza E, Stücker M. Eur Heart J

This commentary refers to ‘Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme’ by E.L. Petersen et al., https://doi.org/10.1093/eurheartj/ehab914 and the discussion piece ‘The everlasting challenge to identify (...)
02:00
The everlasting challenge to identify deep vein thrombosis in both clinical practice and research - Behrendt C, Twerenbold R, Blankenberg S. Eur Heart J

This commentary refers to ‘Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme’ by E.L. Petersen et al., https://doi.org/10.1093/eurheartj/ehab914 and the discussion piece ‘Is there an increased incidence of (...)

5 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Data standards for acute coronary syndrome and percutaneous coronary intervention: the European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) - , , , et al. Eur Heart J

AbstractStandardized data definitions are essential for monitoring and benchmarking the quality of care and patient outcomes in observational studies and randomized controlled trials. There are no contemporary pan-European data standards for the acute coronary syndrome (ACS) and percutaneous (...)

1 April

Eur Heart J https://academic.oup.com/site_5375/

02:00
Long-term results of first-generation S-ICD systems: strong from the start and through the threats of time - Cappato R. Eur Heart J
02:00
SARS-CoV-2 infection markedly increases long-term cardiovascular risk - Liuzzo G, Volpe M. Eur Heart J

Comment on ‘Long-term cardiovascular outcomes of COVID-19’ which was published in Nat Med. https://doi.org/10.1038/s41591-022-01689-3.

30 March

Eur Heart J https://academic.oup.com/site_5375/

02:00
Left main bifurcation treatment: is one stent enough? - den Dekker W, Mahmoud K, Boersma E. Eur Heart J

This commentary refers to ‘The European bifurcation club Left Main Coronary Stent study: a randomized comparison of stepwise provisional vs. systematic dual stenting strategies (EBC MAIN)’, by D. Hildick-Smith et al., https://doi.org/10.1093/eurheartj/ehab283 and the discussion piece ‘The (...)
02:00
The stepwise provisional approach to left main stem bifurcations in Europe - Hildick-Smith D. Eur Heart J

This commentary refers to ‘The European bifurcation club Left Main Coronary Stent study: a randomized comparison of stepwise provisional vs. systematic dual stenting strategies (EBC MAIN)’, by D. Hildick-Smith et al., https://doi.org/10.1093/eurheartj/ehab283 and the discussion piece ‘Left main (...)
02:00
Increased cardiovascular risk in boys born with hypospadias: intriguing observations and remaining questions - Kränkel N. Eur Heart J

24 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
A novel exosome-based therapy for post-MI arrhythmias - Cacheux M, Akar F. Eur Heart J
01:00
Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes - Kraler S, Wenzl F, Georgiopoulos G, et al. Eur Heart J

AbstractAimsThe lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and its shedding product [soluble LOX-1 (sLOX-1)] are implicated in atherosclerotic cardiovascular disease (ASCVD) pathogenesis. Herein, we examined the relationship of sLOX-1 with both fatal events and plaque (...)
01:00
Mischief in the marrow: a root of cardiovascular evil - Libby P, Nahrendorf M, Swirski F. Eur Heart J

23 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Influence of atrial fibrillation on efficacy and safety of omecamtiv mecarbil in heart failure: the GALACTIC-HF trial - Solomon S, Claggett B, Miao Z, et al. Eur Heart J

AbstractAimsIn GALACTIC-HF, the cardiac myosin activator omecamtiv mecarbil compared with placebo reduced the risk of heart failure events or cardiovascular death in patients with heart failure with reduced ejection fraction. We explored the influence of atrial fibrillation or flutter (AFF) on (...)

22 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
In memoriam—Dr. Hikaru Sato: the discoverer of Takotsubo syndrome - Nagai M, Dote K, Ishihara M, et al. Eur Heart J

A pioneer of Japanese reperfusion therapy for acute myocardial infarction, the discoverer and outstanding researcher of ‘Takotsubo syndrome’ passed away on 10 November 2021

19 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Early stakeholder engagement lessons from managing hypertension among people living with human-immunodeficiency virus: an integrated model (MAP-IT) Eur Heart J

National Heart Lung and Blood Institute, United States of America1UG3HL152381-01

18 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Sudden cardiac death in congenital heart disease - Khairy P, Silka M, Moore J, et al. Eur Heart J

AbstractSudden cardiac death (SCD) accounts for up to 25% of deaths in patients with congenital heart disease (CHD). To date, research has largely been driven by observational studies and real-world experience. Drawbacks include varying definitions, incomplete taxonomy that considers SCD as a (...)
01:00
Cardiac sympathetic denervation in the prevention of genetically mediated life-threatening ventricular arrhythmias - Schwartz PJ, Ackerman MJ. Eur Heart J

AbstractProper management of patients affected by genetic disorders causing life-threatening arrhythmias is important for several reasons, including even societal ones, given the predominantly young age of those affected. Incorrect management often has dire consequences, ranging from (...)
01:00
BNP: Biomarker Not Perfect in heart failure with preserved ejection fraction - Shah S. Eur Heart J

17 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Massive device thrombosis, multiple embolisms, and delayed-onset heparin-induced thrombocytopenia: a rare but severe complication of patent foramen ovale closure Eur Heart J

A 40-year-old man was referred to our centre for a patent foramen ovale (PFO) closure 8 months after a cryptogenic stroke. A Cardioform Septal Occluder device (GSO; W.L. Gore and Associates) was successfully positioned with transoesophageal echocardiography (TEE) guidance. A 100 UI/kg bolus of (...)
01:00
Revisiting the definition of perioperative myocardial infarction after coronary artery bypass grafting Eur Heart J
01:00
P2Y12 inhibitor adherence trajectories in patients with acute coronary syndrome undergoing percutaneous coronary intervention: prognostic implications - Turgeon R, Koshman S, Dong Y, et al. Eur Heart J

AbstractAimsPost-acute coronary syndrome (ACS) P2Y12 inhibitor non-adherence is common and associated with greater risk of major adverse cardiovascular events (MACEs). Non-adherence can follow different trajectories from an inability to initiate, implement, or continue therapy for the intended (...)
01:00
Adherence to P2Y12 inhibitors in acute coronary syndrome after a percutaneous coronary intervention: what can we improve? - Han Y, Li Y. Eur Heart J
01:00
Encouraging physical activity amongst older adults; where should we stand? - Hellénius M. Eur Heart J
01:00
Vascular dysfunction and increased cardiovascular risk in hypospadias - Lucas-Herald A, Montezano A, Alves-Lopes R, et al. Eur Heart J

AbstractAimsHypogonadism is associated with cardiovascular disease. However, the cardiovascular impact of hypogonadism during development is unknown. Using hypospadias as a surrogate of hypogonadism, we investigated whether hypospadias is associated with vascular dysfunction and is a risk (...)

16 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Cereblon, a novel target in heart failure: but is calcium really everything? - Sequeira V, Maack C. Eur Heart J
01:00
800 years of research at the University of Padua (1222–2022): contemporary insights into Sports Cardiology - Corrado D, Zorzi A, Basso C, et al. Eur Heart J

Holding a long tradition of excellence since 1222, the University of Padua is one of the oldest and most prestigious academic centres in Europe. In the 16th–17th centuries, milestone achievements from Padua's researchers in astronomy, medicine, and natural philosophy contributed to the cultural (...)

11 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: Cardiovascular health after menopause transition, pregnancy disorders, and other gynaecologic conditions: a consensus document from European cardiologists, gynaecologists, and endocrinologists Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehaa1044.
01:00
Bone marrow activation in response to metabolic syndrome and early atherosclerosis - Devesa A, Lobo-González M, Martínez-Milla J, et al. Eur Heart J

AbstractAimsExperimental studies suggest that increased bone marrow (BM) activity is involved in the association between cardiovascular risk factors and inflammation in atherosclerosis. However, human data to support this association are sparse. The purpose was to study the association between (...)
01:00
Corrigendum to: Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab834.

10 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Circadian nuclear receptor Rev-erb? is expressed by platelets and potentiates platelet activation and thrombus formation - Shi J, Tong R, Zhou M, et al. Eur Heart J

AbstractAimsAdverse cardiovascular events have day/night patterns with peaks in the morning, potentially related to endogenous circadian clock control of platelet activation. Circadian nuclear receptor Rev-erb? is an essential and negative component of the circadian clock. To date, the (...)
01:00
Chrono-pharmacology-based antiplatelet therapy for acute myocardial infarction - Tual-Chalot S, Stellos K. Eur Heart J
01:00
Electrical management of heart failure: from pathophysiology to treatment - Prinzen F, Auricchio A, Mullens W, et al. Eur Heart J

AbstractElectrical disturbances, such as atrial fibrillation (AF), dyssynchrony, tachycardia, and premature ventricular contractions (PVCs), are present in most patients with heart failure (HF). While these disturbances may be the consequence of HF, increasing evidence suggests that they may (...)
01:00
Metabolic/bariatric surgery protects against cardiovascular disease - Mingrone G, Castagneto-Gissey L, Bornstein S. Eur Heart J
01:00
Coronary artery fistula bypassed the left main coronary artery blocked by a large cardiogenic thrombus - Wang J, Chen H, Zhang L. Eur Heart J

Wuhan Asia General Hospital
01:00
To repair or not to repair: the dilemma of tricuspid regurgitation associated with left-sided valvular heart disease - Galiuto L, Massetti M. Eur Heart J

Comment on ‘Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation’ published in the New England Journal of Medicine (https://doi.org/10.1056/NEJMoa2115961).
01:00
Risk scoring in secondary prevention: a basis for informed clinical decisions in the context of ever-expanding treatments - Sattar N, Welsh P. Eur Heart J
01:00
Mitral valve prolapse: will genetics finally solve the puzzle? - Trenkwalder T, Krane M. Eur Heart J

9 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Biological substrate modification suppresses ventricular arrhythmias in a porcine model of chronic ischaemic cardiomyopathy - Dawkins JF, Ehdaie A, Rogers R, et al. Eur Heart J

AbstractAimsCardiomyopathy patients are prone to ventricular arrhythmias (VA) and sudden cardiac death. Current therapies to prevent VA include radiofrequency ablation to destroy slowly conducting pathways of viable myocardium which support re-entry. Here, we tested the reverse concept, namely (...)

8 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Advanced subspecialty cardiology training in India in 2022: challenges and future directions - Bhat V, Ozair A, Kumar A, et al. Eur Heart J
01:00
European Reference Network for rare, low prevalence, or complex diseases of the heart (ERN GUARD-Heart): 5 year anniversary - Amin A, Biller R, Charron P, et al. Eur Heart J
01:00
Cardiotoxicity from chimeric antigen receptor-T cell therapy for advanced malignancies - Totzeck M, Michel L, Lin Y, et al. Eur Heart J

AbstractChimeric antigen receptor (CAR)-T cell therapy is the next revolutionary advance in cancer therapy. By using ex vivo engineered T cells to specifically target antigens, a targeted immune reaction is induced. Chimeric antigen receptor-T cell therapy is approved for patients suffering (...)
01:00
Unloading left heart with a shunt device shows no benefits in heart failure with preserved ejection fraction but supports the importance of phenotyping patients in clinical trials - Volpe M, Liuzzo G. Eur Heart J

Comment on ‘Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomized, multicentre, blinded, sham-controlled trial’ which was published in The Lancet, https://doi.org/10.1016/S0140-6736(22)00016-2.

7 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Targeting the CCL2–CCR2 axis for atheroprotection - Georgakis M, Bernhagen J, Heitman L, et al. Eur Heart J

AbstractDecades of research have established atherosclerosis as an inflammatory disease. Only recently though, clinical trials provided proof-of-concept evidence for the efficacy of anti-inflammatory strategies with respect to cardiovascular events, thus offering a new paradigm for lowering (...)
01:00
Complete resolution of apical hypertrophy and fibrosis: the role of serial cardiovascular magnetic resonance tissue characterization to differentiate hypertrophic cardiomyopathy from myocarditis - Wilson J, Muthumala A, Khanji M. Eur Heart J

A 71-year-old female with Type 2 diabetes mellitus, hypertension, and hypercholesterolaemia presented to the emergency department with a 2-day history of heavy chest pain radiating to the left shoulder. Electrocardiogram showed normal sinus rhythm with no evidence of ischaemia, but serial (...)
01:00
Corrigendum to: Proteomics for the prediction and prevention of atherosclerotic disease Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehac036.

5 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Personalized antithrombotic treatment of cardiovascular disease: a glimpse into the future based on current knowledge - Crea F. Eur Heart J
01:00
Time for a paradigm shift? Making the case for tailored selection of antiplatelet therapy - O’Donoghue ML, Marston NA. Eur Heart J

This editorial refers to ‘Comparative effects of guided vs. potent P2Y12 inhibitor therapy in acute coronary syndrome: a network meta-analysis of 61 898 patients from 15 randomized trials’, by M. Galli et al., https://doi.org/10.1093/eurheartj/ehab836.

4 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
A training project to promote clinical research among young cardiologists - Di Fusco S, Maggioni A, Colivicchi F. Eur Heart J

Providing guidance to young cardiologists by promoting collaboration and professional development is one of the main goals that the Italian Association of Hospital Cardiologists (ANMCO) shares with the European Society of Cardiology. In 2021, the ANMCO President, Prof Furio Colivicchi, launched (...)
01:00
Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis - van Veldhuisen S, Gorter T, van Woerden G, et al. Eur Heart J

AbstractAimsObesity is a global health problem, associated with significant morbidity and mortality, often due to cardiovascular (CV) diseases. While bariatric surgery is increasingly performed in patients with obesity and reduces CV risk factors, its effect on CV disease is not established. We (...)
01:00
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse - Roselli C, Yu M, Nauffal V, et al. Eur Heart J

AbstractAimsMitral valve prolapse (MVP) is a common valvular heart disease with a prevalence of >2% in the general adult population. Despite this high incidence, there is a limited understanding of the molecular mechanism of this disease, and no medical therapy is available for this disease. We (...)

3 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: European Heart Journal quality standards Eur Heart J

European Heart Journal, https://doi:10.1093/eurheartj/ehab324.

2 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
NSTEMI management: a fall from GRACE? - Schiele F, Meneveau N. Eur Heart J

1 March

Eur Heart J https://academic.oup.com/site_5375/

01:00
Differential cardiovascular effects of disease-modifying antirheumatic drugs in rheumatoid arthritis - Galiuto L, Patrono C. Eur Heart J

Comment on ‘Cardiovascular and cancer risk with tofacitinib in rheumatoid arthritis’ published in N Engl J Med. https://doi.org/10.1056/NEJMoa2109927.

25 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Polygenic risk score: a tool ready for clinical use? - Kavousi M, Schunkert H. Eur Heart J
01:00
Sodium-containing acetaminophen and cardiovascular outcomes in individuals with and without hypertension - Zeng C, Rosenberg L, Li X, et al. Eur Heart J

AbstractAimsPrevious studies have found high sodium intake to be associated with increased risks of cardiovascular disease (CVD) and all-cause mortality among individuals with hypertension; findings on the effect of intake among individuals without hypertension have been equivocal. We aimed to (...)
01:00
The sodium hidden in medication: a tough pill to swallow - Schutte A, Neal B. Eur Heart J

23 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study - Lu X, Liu Z, Cui Q, et al. Eur Heart J

AbstractAimsTo construct a polygenic risk score (PRS) for coronary artery disease (CAD) and comprehensively evaluate its potential in clinical utility for primary prevention in Chinese populations.Methods and resultsUsing meta-analytic approach and large genome-wide association results for CAD (...)

22 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: Nudging within learning health systems: next generation decision support to improve cardiovascular care Eur Heart J

European Heart Journal,https://doi.org/10.1093/eurheartj/ehac030.
01:00
Cereblon contributes to cardiac dysfunction by degrading Cav1.2? - Park N, Marquez J, Pham T, et al. Eur Heart J

AbstractAimsCereblon (CRBN) is a substrate receptor of the E3 ubiquitin ligase complex that was reported to target ion channel proteins. L-type voltage-dependent Ca2+ channel (LTCC) density and dysfunction is a critical player in heart failure with reduced ejection fraction (HFrEF). However, (...)

21 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Is APAF-CRT robust enough to change clinical practice? - Brignole M, Soranna D, Rienstra M. Eur Heart J

This commentary refers to ‘AV junction ablation and cardiac resynchronization for patients with permanent atrial fibrillation and narrow QRS: the APAF-CRT mortality trial’, by M. Brignole et al., https://doi.org/10.1093/eurheartj/ehab569 and the discussion piece ‘Ablate and pace for patients with (...)
01:00
Ablate and pace for patients with atrial fibrillation: a fragile option? - Kaur H, McIntyre W, Belley-Côté E. Eur Heart J

This commentary refers to ‘AV junction ablation and cardiac resynchronization for patients with permanent atrial fibrillation and narrow QRS: the APAF-CRT mortality trial’, by M. Brignole et al., https://doi.org/10.1093/eurheartj/ehab569 and the discussion piece ‘Is APAF-CRT robust enough to (...)
01:00
Clinical strokes in atrial fibrillation: the tip of the iceberg - Jared Bunch T, Steinberg B. Eur Heart J
01:00
Corrigendum to: 2021 ESC/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab395.
01:00
Calcific aortic valve disease: novel insights into nitric oxide signalling - Kraler S, Garg V, Akhmedov A. Eur Heart J
01:00
Inflammation, targeted proteomics, and microvascular dysfunction: the new frontiers of ischaemic heart disease - Crea F. Eur Heart J
01:00
Percutaneous coronary intervention vs. coronary artery bypass graft for left main coronary artery disease: a never-ending debate - Liuzzo G, Volpe M. Eur Heart J

Comment on ‘Percutaneous coronary intervention with drug-eluting stents versus coronary artery bypass grafting in left main coronary artery disease: an individual patient data meta-analysis’ published in Lancet. (https://doi.org/10.1016/S0140-6736(21)02334-5).

18 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Not only lungs: COVID-19 hits platelets as well - Bongiovanni D, Klug M, Valgimigli M, et al. Eur Heart J

Despite the worldwide diffusion of SARS-CoV-2 infection, still little is known concerning the mechanism leading to multi-organ damage in coronavirus disease 2019 (COVID-19). It is now clear that the coronavirus does not only affect the pulmonary system but causes damage to several other (...)
01:00
Serial histopathologic assessment of fulminant myocarditis after the first mRNA COVID-19 vaccine dose - Koiwaya H, Nishihira K, Tomozoe K, et al. Eur Heart J

A 77-year-old man with hypertension presented to the emergency department with fever and cardiogenic shock 8 days after receiving the first dose of the BNT16B2b2 mRNA COVID-19 vaccine (Pfizer-BioNTech). Nucleic acid amplification via polymerase chain reaction with a nasopharyngeal swab sample (...)
01:00
Percutaneous closure of left ventricular pseudoaneurysm after direct surgical mitral valve implantation of balloon-expandable transcatheter prosthesis in severe mitral annular calcification - Oechslin L, Corti R, Biaggi P, et al. Eur Heart J

A 76-year-old female patient who had undergone quadruple coronary bypass surgery and aortic valve replacement 10 years earlier was referred to our clinic for severe symptomatic mitral valve stenosis secondary to extensive mitral annular calcification (MAC). Due to the high surgical risk, the (...)
01:00
Heart and kidney: towards an integrated approach to secondary mitral regurgitation - Rudolph V. Eur Heart J

17 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Ethnicity-dependent performance of the Global Registry of Acute Coronary Events risk score for prediction of non-ST-segment elevation myocardial infarction in-hospital mortality: nationwide cohort study - Moledina S, Kontopantelis E, Wijeysundera H, et al. Eur Heart J

AbstractAimsThe Global Registry of Acute Coronary Events (GRACE) score was developed to evaluate risk in patients with the acute coronary syndrome with or without ST-segment elevation. Little is known about its performance at predicting in-hospital mortality for ethnic minority patients.Methods (...)
01:00
Renal denervation therapy for hypertension: all that glitters is not gold - Ram C. Eur Heart J

Systemic hypertension is a common condition that substantially increases the risk of cardiovascular events. Despite this, blood pressure (BP) control with pharmacological antihypertensive therapy remains challenging and control rates are well below the optimal level. This common unmet need (...)
01:00
Silent brain infarcts impact on cognitive function in atrial fibrillation - Kühne M, Krisai P, Coslovsky M, et al. Eur Heart J

AbstractAimsWe aimed to investigate the association of clinically overt and silent brain lesions with cognitive function in atrial fibrillation (AF) patients.Methods and resultsWe enrolled 1227 AF patients in a prospective, multicentre cohort study (Swiss-AF). Patients underwent standardized (...)
01:00
Corrigendum to: 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab364.
01:00
Corrigendum to: PCSK9 inhibition in patients with heart failure – neutral or harmful intervention? Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab913.

15 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
High-sensitivity cardiac troponin I after coronary artery bypass grafting for post-operative decision-making Eur Heart J

AbstractAimsCurrent troponin cut-offs suggested for the post-operative workup of patients following coronary artery bypass graft (CABG) surgery are based on studies using non-high-sensitive troponin assays or are arbitrarily chosen. We aimed to identify an optimal cut-off and timing for a (...)
01:00
Hybrid aortic arch repair for unibody single-branched endograft induced retrograde aortic dissection - Zhang Y, Yang P, Lu C, et al. Eur Heart J

National Natural Science Foundation of China10.13039/50110000180981670327Sichuan Science and Technology Program2019YJ00462018SZ0384West China Hospital, Sichuan University10.13039/5011000133652020HXJS0152019HXFH027
01:00
Unmet needs in the management of arrhythmias among heart failure patients in Africa - Mutagaywa R, Chin A, Karaye K, et al. Eur Heart J

Several studies suggest that the burden of heart failure (HF) in Africa is on the increase with patients presenting late to hospitals.1 Such a high burden is fuelled by an increase in the prevalence of cardiovascular risk factors, sub-optimal management of these risk factors, and an ageing (...)
01:00
A polypill for cardiovascular disease prevention with a focus on non-alcohol steatohepatitis - Joseph P, Yusuf S. Eur Heart J
01:00
Transcatheter mitral valve in ring implantation: a word of caution based on histopathological workup - Schmiady M, Carrel T, Sigler M, et al. Eur Heart J

Cardiac surgery is the current gold standard for mitral valve repair. However, surgery may carry a high perioperative risk in critically ill patients. Transcatheter valve-in-ring and valve-in-valve implantation has emerged as a promising alternative in these patients, but significant residual (...)
01:00
Advancing therapeutic targeting of the vulnerable plaque - Newman A, Cyr Y, Moore K. Eur Heart J
01:00
Estimation of recurrent atherosclerotic cardiovascular event risk in patients with established cardiovascular disease: the updated SMART2 algorithm - Hageman S, McKay A, Ueda P, et al. Eur Heart J

AbstractAimsThe 10-year risk of recurrent atherosclerotic cardiovascular disease (ASCVD) events in patients with established ASCVD can be estimated with the Secondary Manifestations of ARTerial disease (SMART) risk score, and may help refine clinical management. To broaden generalizability (...)
01:00
Heart failure: a 70 year Odyssey - Braunwald E. Eur Heart J
01:00
Proteomics for the prediction and prevention of atherosclerotic disease - Ridker PM. Eur Heart J
01:00
Volunteer first responders for out-of-hospital cardiac arrest at home: the missing link for improved survival? - Malta Hansen C, Folke F. Eur Heart J

12 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
A comprehensive update on valvular heart disease: from mechanisms to Guidelines - Crea F. Eur Heart J

11 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Erratum to: Leadless pacing: is this the end of the road for transvenous pacemakers? Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab769.

10 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Endothelial cell-derived tetrahydrobiopterin prevents aortic valve calcification - Liu Z, Dong N, Hui H, et al. Eur Heart J

AbstractAimsTetrahydrobiopterin (BH4) is a critical determinant of the biological function of endothelial nitric oxide synthase. The present study was to investigate the role of valvular endothelial cell (VEC)-derived BH4 in aortic valve calcification.Methods and resultsPlasma and aortic valve (...)
01:00
New therapeutic targets in the prevention of atherosclerotic cardiovascular disease - Crea F. Eur Heart J

9 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Impact of myocardial injury after coronary artery bypass grafting on long-term prognosis Eur Heart J

AbstractAimsThe most appropriate definition of perioperative myocardial infarction (pMI) after coronary artery bypass grafting (CABG) and its impact on clinically relevant long-term events is controversial. We aimed to (i) analyse the incidence of pMI depending on various current definitions in (...)
01:00
You can only change what you measure: an argument for more detailed characterization in the Fontan circulation Eur Heart J
01:00
Early and late-onset syncope: insight into mechanisms - Torabi P, Rivasi G, Hamrefors V, et al. Eur Heart J

AbstractAimsUnexplained syncope is an important clinical challenge. The influence of age at first syncope on the final syncope diagnosis is not well studied.Methods and resultsConsecutive head-up tilt patients (n = 1928) evaluated for unexplained syncope were stratified into age groups P < (...)
01:00
Corrigendum to: Heart failure with preserved ejection fraction in humans and mice: embracing clinical complexity in mouse models Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab389.
01:00
Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality - Verbrugge F, Omote K, Reddy Y, et al. Eur Heart J

AbstractBackgroundA substantial proportion of patients with heart failure (HF) with preserved ejection fraction (HFpEF) present with normal natriuretic peptide (NP) levels. The pathophysiology and natural history for this phenotype remain unclear.Methods and resultsConsecutive subjects (...)
01:00
Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture–prone atherosclerotic plaques - Edsfeldt A, Swart M, Singh P, et al. Eur Heart J

AbstractAimsInflammation is a key factor in atherosclerosis. The transcription factor interferon regulatory factor-5 (IRF5) drives macrophages towards a pro-inflammatory state. We investigated the role of IRF5 in human atherosclerosis and plaque stability.Methods and resultsBulk RNA sequencing (...)
01:00
Targeted proteomics improves cardiovascular risk prediction in secondary prevention - Nurmohamed NS, Belo Pereira JP, Hoogeveen RM, et al. Eur Heart J

AbstractAimsCurrent risk scores do not accurately identify patients at highest risk of recurrent atherosclerotic cardiovascular disease (ASCVD) in need of more intensive therapeutic interventions. Advances in high-throughput plasma proteomics, analysed with machine learning techniques, may (...)
01:00
Fighting against sudden cardiac death: need for a paradigm shift—Adding near-term prevention and pre-emptive action to long-term prevention - Marijon E, Garcia R, Narayanan K, et al. Eur Heart J

AbstractMore than 40 years after the first implantable cardioverter-defibrillator (ICD) implantation, sudden cardiac death (SCD) still accounts for more than five million deaths worldwide every year. Huge efforts in the field notwithstanding, it is now increasingly evident that the current (...)

8 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Sex equality or sex equity: what are we looking for in treating limb-threatening ischaemia? - Kingsmore D, Brittenden J. Eur Heart J
01:00
New insights into transcatheter edge-to-edge repair: filling a gap for undertreatment of primary mitral regurgitation in the elderly? - Iung B, Urena M. Eur Heart J

4 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Clinical significance of epicardial fat in suspected angina pectoris: an observational study - Dadarwal A, Garg N, Kapoor A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundEpicardial adipose tissue (EAT) is the visceral fat between pericardium and visceral epicardium and is the source of several endocrine and inflammatory mediators. It also has paracrine affects in the neighboring coronary (...)
01:00
Homocysteine predicts vascular target organ damage in hypertension and may serve as guidance for first-line antihypertensive therapy - Carnagarin R, Schlaich M. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Foundation. Main funding source(s): the primary author is supported by the Australian National Heart Foundation post docctoral fellowshipOnBehalfDobney Hypertension CentreBackgroundHomocysteine is an independent risk factor for (...)
01:00
Invasive validation of the different echo parameters and cut-offs among the trilogy of left ventricular filling pressure assessment guidelines: EACVI/ASE 2016, ESC 2016, HFA 2019 - Barakat A, Alsaadi A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): Al-mouwasat University Hospital and University Heart Surgery Center in Damascus, Syrian Arab Republic.BackgroundLeft ventricular filling pressure assessment is a challenge. Three guidelines (...)
01:00
ECG education for first-grade medical students detecting Epsilon and J waves in patients with arrhythmogenic right ventricular cardiomyopathy in comparison with specialists for arrhythmia treatment - Funabashi N, Nakamura K, Sasaki T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundMedical students find Epsilon and J wave diagnoses by electrocardiogram (ECG) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) difficult.PurposeTo evaluate the inter observer reliability for detecting (...)
01:00
Angiographic Profiles in Persistent Non-Valvular Atrial Fibrillation Patients - Batta A, Sharma Y, Makkar K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfCardiology dept. PGIMER, ChandigarhBackgroundThe relationship of atrial fibrillation (AF) with coronary artery disease (CAD) is well established. Atrial ischemia due to obstructive CAD has been identified as one of the key (...)
01:00
The influence of physical rehabilitation on bone mineral density in patients with chronic heart failure before and after heart transplantation - Sujayeva V, Rudenka E, Koshlataya O, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Objectiveto estimate the influence of physical rehabilitation on bone metabolism density (BMD) in patients with heart failure (HF) before and after heart transplantation (HT).Methods. We studied 95 patients with CHF before and after (...)
01:00
Cardiac resynchronization therapy in patients with true left bundle branch block : a systematic review and meta-analysis - Cheng C. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Cardiac resynchronization therapy has been shown to improve clinical outcomes of heart failure. Still, about 30% of the patients had no response to CRT. A stricter LBBB criteria emphasizing notched or slurred R waves was (...)
01:00
Prevalence and characteristics of non-ST-segment elevation in acute myocardial infarction with insignificant coronary artery disease - Sricholwattana S, Chaipromprasit J, Kosum P. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): King Chulalongkorn Memorial HospitalBackground Acute myocardial infarction is mostly associated with obstructive coronary artery disease. 8% to 12% of patients have insignificant coronary artery (...)
01:00
The use of bedside haemodynamic parameters to predict risk and in-hospital outcomes in non-ST elevation acute coronary syndromes: data from resource- limited settings in Iraq - Dakhil Z. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThere is lack of data on the value of bedside hemodynamic parameters in predicting risk and outcomes in NSTE-ACS. This study aimed to assess if the following bedside haemodynamic tests : mean arterial pressure (MAP) [DBP + (...)
01:00
Clinical implications of troponin-T elevations following TAVR - Imamura T, Oshima A, Onoda H, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundBaseline and post-procedural elevations in serum troponin-T levels are associated with increased morbidity and mortality following transcatheter aortic valve replacement (TAVR). However, the prognostic impact of change in (...)
01:00
Single center experience of transcatheter aortic valve implantation in severe aortic stenosis: study of mid-term clinical outcome - Tey Y, Aris F, Jalaluddin M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BACKGROUNDTranscatheter Aortic Valve Implantation (TAVI) had revolutionized the treatment and outcome of symptomatic severe aortic stenosis (AS) since its introduction. In 2009, our center performed the first TAVI in Malaysia and (...)
01:00
Direct oral anticoagulant vs low molecular weight heparin for the treatment of venous thromboembolism associated with malignancy: a meta- analysis - Lastimosa H. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundVenous thromboembolism (VTE) is a major cause of morbidity and mortality in cancer patients and treatment of cancer associated thromboembolism is challenging. Low molecular weight heparin (LMWH) has been the standard of (...)
01:00
Anticoagulation practices and venous thromboembolism in COVID-19 patients in a Philippine tertiary hospital - Ramos M. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.INTRODUCTIONCOVID-19 poses an increased risk for thrombosis and initiation of prophylactic anticoagulation has been shown to have mortality benefit in earlier studies. However, the use of full dose anticoagulation as prophylaxis and (...)
01:00
The effects of Kaatsu training on an acute angiogenic response in post-interventional rehabilitation of peripheral arterial disease patients - Wlodarczyk A, Wachsmann-Maga A, Schonborn M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundAtherosclerosis as the main cause of death in adults is one of the greatest challenges of modern medicine. Peripheral arterial disease (PAD) is a condition with worldwide increasing occurrence affecting more than 20% of (...)
01:00
The impact of blood pressure variation on mortality and symptomatic intracerebral hemorrhage in stroke patients after thrombolytic therapy - Kotruchin P, Kliangsa-Ard H, Mitsungnern T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public Institution(s). Main funding source(s): Faculty of Medicine, Khon Kaen UniversityIntroduction Blood pressure variation (BPV) was one of the risk factors for unfavorable stokes outcomes. However, the association between BPV and (...)
01:00
Incidence of gastrointestinal bleeding after transoesophageal echocardiography in patients with gastro-oesophageal varices: a systematic review and meta-analysis - Hui R, Leung C. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionTransoesophageal echocardiography (TEE) is useful for cardiac assessment and intraoperative monitoring. However, the safety of TEE in cirrhotic patients with gastro-oesophageal varices has remained uncertain.PurposeThis (...)
01:00
When type 2 diabetes coexists with atrial fibrillation in Middle Eastern patients: Clinical profiles and utilization of oral anticoagulant agents - Hammoudeh A, Alzyoud W, Ja"ara D, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfThe Jordan Atrial Fibrillation (JoFib) StudyBackground. Studies from different regions in the world have shown that patients with atrial fibrillation (AF) who have type 2 diabetes mellitus (T2D) have unfavorable baseline (...)
01:00
Impact of preprocedural upper gastrointestinal endoscopy for pulmonary vein isolation - single-center experience of 400 patients - Grosse Meininghaus D, Kleemann T. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionMucosal esophageal lesions (ELs) are reported in 10-40% after pulmonary vein isolation (PVI) and may be precursors of (almost always lethal) atrio-esophageal fistula (AEF). Although mechanisms of lesion progression are (...)
01:00
Echinacoside inhibited cardiomyocyte apoptosis and improved heart function in heart failure rats induced by isoproterenol via suppressing nadph/ros/atf6/chop associated endoplasmic reticulum stress - Ni Y, Gao L, Zhu W. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Other. Main funding source(s): Shaanxi Provincial Key Research and Development Projects (2019SF-218)BackgroundEndoplasmic reticulum (ER) stress played an essential role in the development and progression of HF due to it could induce (...)
01:00
Clustering analysis based on automated electrocardiographic measurements to identify prognostically distinct phenotypes in patients hospitalized for heart failure: a retrospective cohort study - Chan J, Zhou J, Li A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundHeart failure (HF) is a heterogeneous disease with complex structural and electrophysiological derangements of the heart. Attempts to classify HF from the electrophysiological perspective are lacking.PurposeTo use (...)
01:00
In-hospital outcomes of acute heart failure according to left ventricular ejection fraction: a single-center retrospective cohort study - Han-Gla A, Viriyanukulvong K, Ariyachaipanich A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundAcute heart failure (AHF) is a common cause of hospitalization and associated with high mortality rate. However, the study on outcomes of AHF patients classified by left ventricular ejection fraction (LVEF) in Thailand (...)
01:00
Do more specific assays for B-type natriuretic peptides better predict heart failure in breathless patients than the currently used assays? - Lewis L, Raudsepp S, Whitlow J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Heart Foundation of New Zealand Health Research Council of New ZealandIntroductionThe cardioprotective B-type natriuretic peptide (BNP1-32) and its inactive congener N-terminal (...)
01:00
Efficacy and safety of HDL/apoA-1 mimetics on human and mice with atherosclerosis: a systematic review and meta-analysis - Abudukeremu A, Li H, Sun R, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): the National Natural Science Foundation of ChinaBackgroundLow high-density lipoprotein cholesterol (HDL-C) level as a residual risk factor of cardiovascular disease (CVD) is (...)
01:00
Primary PCI in the very elderly: A study of outcomes in patients aged > 85 years with STEMI - Jariwala P, Jadhav K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundPrimary percutaneous coronary intervention (PPCI) as management for acute STEMI is a well-established, evidence-based treatment offered across India. Evidence of benefit in the very elderly is sparse. With an aging (...)
01:00
Cost and prescription trends of P2Y12 inhibitors in Australia over the last decade - Abrahams T, Brown A, Pol D. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundCoronary artery disease (CAD) remains one of the leading causes of mortality worldwide and in Australia, and places significant burden on healthcare costs. [1,2] Dual antiplatelet therapy (DAPT) is guideline therapy (...)
01:00
The effect of remote ischemic post-conditioning on left ventricular ejection fraction in STEMI patients undergoing primary percutaneous coronary intervention - Fadil M. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background/IntroductionPrimary Percutaneous Coronary Intervention (PPCI) in ST-Segment Elevation Myocardial Infarction (STEMI) is an effective method to limit the infarct area, reduce clinical symptoms, and improve clinical (...)
01:00
Left main PCI with second-generation DES: a single-centre experience - Jariwala P, Jadhav K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundTo characterise patients and procedures with left main (LM) percutaneous coronary intervention (PCI) and to evaluate their outcomes.MethodsSingle-centre, retrospective study performed from January 2018 to December 2019 in (...)
01:00
Analysis of clinical features and coronary angiography in 10 patients with de winter syndrome - Ni N. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfGuohua NiObjectiveTo investigate the clinical characteristics and electrocardiogram (ECG) changes of patients with de winter syndrome, so as to enhancing the awareness of de Winter ECG pattern and conducting early emergency (...)
01:00
Circulating extracellular vesicles correlate with nocturnal blood pressure and vascular organ damage and may serve as an integrative biomarker of vascular health. - Lugo Gavidia L, Burger D, Robinson S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public Institution(s). Main funding source(s): National Council on Science and Technology, Mexico (CONACYT).Background Elevated blood pressure (BP) has been associated with increased levels of circulating extracellular vesicles (EVs) (...)
01:00
Study on the correlation between ambulatory blood pressure and left atrial diameter in patients with treated and controlled office hypertension - Zhang L, Zhang X, Song W, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Patients suffered from different kinds of target organ damage even after years of standardized treatment in clinic. PurposeTo explore the relationship between ABPM and LAD in patients with treated essential (...)
01:00
Serum uric acid is positively associated with systolic and diastolic blood pressure in young adults - Correa T, De Oliveira I. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Science and Technology Department of the Brazilian Ministry of Health.IntroductionUric acid is the final product of purine metabolism, and its increase can be related to (...)
01:00
A survey-based comparison of cardiovascular health risk behaviours in Indian men and women during the pandemic - Chockalingam P, Natarajan V, Sekar T. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundCardiovascular disease (CVD), the leading cause of mortality globally, is caused by a combination of behavioral, clinical and genetic risk factors. The rising prevalence of unhealthy diet, inadequate exercise, psychosocial (...)
01:00
Epidemiology of obstructive sleep apnea in older patients with stable cardiovascular disease and chronic kidney disease - Efremova E, Shutov A, Serov V, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Obstructive sleep apnea (OSA) is diagnosed late, especially in older people. The presence of chronic hypoxia and glomerular hypertension decrease renal function in patients with OSAS, which causes the progression of chronic kidney (...)
01:00
Programmed Cell Death 1 (PD-1) and Programmed Cell Death Ligand 1 (PD-L1) inhibitors and adverse cardiovascular events: a population-based study - Lee S, Zhou J, Lakhani I, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfCardiovascular Analytics GroupBackgroundProgrammed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) inhibitors are major classes of immune checkpoint inhibitors that are increasingly used for cancer treatment. However, (...)
01:00
Serial echocardiography assessment and clinical outcomes among pregnant women with Tetralogy of Fallot - Hon N, Wu M, Yu S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Following advancements in intracardiac repair of Tetralogy of Fallot (TOF), a greater proportion of patients survive well beyond child-bearing age. Pulmonary regurgitation (PR) and subsequent progressive right ventricular dilatation (...)
01:00
Role of prenatal cardiovascular magnetic resonance imaging in determining pregnancy risk in repaired Tetralogy of Fallot patients - Hon N, Wu M, Yu S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Addressing pregnancy risks poses as a new challenge among women with repaired tetralogy of Fallot (TOF). The high-output state of pregnancy may predispose women to late complications of repaired TOF. However, guidelines regarding (...)
01:00
Accuracy of global longitudinal and territorial longitudinal strain in determining myocardial viability in out of window period Anterior wall myocardial infarction patients - Batta A, Sharma Y, Makkar K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundPrimary percutaneous intervention remains the principal treatment modality for anterior wall myocardial infarction (AWMI). However, a large fraction of patients especially in the developing countries present outside the (...)
01:00
OCT-guided left-main PCI, a retrospective single-center analysis - Jariwala P, Jadhav K, Jadhav K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundIt is known that PCI is associated with non-optimal stent implantation utilizing angiography for only left main lesions as well as for bifurcation lesions and is characterised by a high risk of adverse long-term effects. (...)
01:00
High power short duration (HPSD) versus lower power longer duration (LPLD) atrial fibrillation ablation: a multi-centre randomised controlled trial (HiLo-HEAT study) - Chieng D, Sugumar H, Segan L, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Lower power (25W) longer duration (LPLD) radiofrequency (RF) ablation has conventionally been used on the posterior wall during pulmonary vein isolation (PVI) for atrial fibrillation (AF), to attenuate the risk of (...)
01:00
A multicentre survey of paediatric out-of-hospital cardiac arrest incidence, aetiology, and survival in New South Wales over an 11-year period - Youssef D, Singh A, Ayer J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionOut-of-hospital cardiac arrest (OOHCA) is commonly associated with pulseless ventricular tachycardia and ventricular fibrillation (VT/VF) and cardiac aetiologies. One New South Wales (NSW) ambulance registry reported(1) (...)
01:00
Acute procedural outcomes of his bundle pacing with or without electrophysiology mapping system: a multicenter study - Loo G, De Leon J, Seow S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionHis bundle pacing (HBP) is associated with improved clinical outcomes compared to right ventricular apical pacing. However, it can be technically challenging and may result in prolonged fluoroscopy and procedural (...)
01:00
Clinical value of the HATCH score for predicting adverse outcomes in patients with heart failure - Shibata N, Kondo T, Morimoto R, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe HATCH score is employed as a risk assessment tool for atrial fibrillation (AF) development. However, the impact of the HATCH score on the long-term adverse outcomes in patients with acute heart failure (AHF) is (...)
01:00
Prognostic value of machine learning for acute heart failure - Shimizu M, Miyazaki H, Cho S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundAt onset of acute heart failure (AHF), various clinical fundamental parameters including vital sign, laboratory data, or initial treatment were investigated, and we can roughly estimate the prognosis. However, machine (...)
01:00
An echocardiographic algorithm for predicting coronary artery disease: is it time to establish one? - Barakat A, Alsaadi A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): Al-mouwasat University Hospital and University Heart Surgery Center in Damascus, Syrian Arab Republic.BackgroundCoronary artery disease (CAD) is a major clinical issue. CAD affects left (...)
01:00
Differential association between significant coronary stenosis and cardiac troponin T serial algorithms in renal dysfunction patients diagnosed with non-ST-segment elevation acute coronary syndromes - Kotruchin P, Tangpaisarn T, Srimakam N, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public Institution(s). Main funding source(s): Faculty of Medicine Khon Kaen UniversityBackgroundHigh-sensitivity cardiac troponin T (hs-cTnT) is recommended for diagnosing non-ST segment elevation acute coronary syndromes (NSTE-ACS). (...)
01:00
Knowledge and attitudes amongst internal medicine clinicians in referring valvular heart disease patients : a multi-centre survey study - Raja Shariff R, Ibrahim K, Zainal Abidin H, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundWith advancement in valvular interventions, outcomes of valvular heart disease (VHD) patients have improved dramatically. However, very little is known regarding levels of knowledge and attitudes amongst non-cardiology (...)
01:00
Infective endocarditis post-transcatheter aortic valve replacement: a systematic review of epidemiology, clinical findings and prognosis - Jaiswal V, Jaiswal A, Ishak A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundTranscatheter aortic valve replacement (TAVR) is a minimally invasive, catheter-based procedure to replace calcified narrow aortic valves. Available data on prosthetic valve endocarditis (PVE) post TAVR is limited to small (...)
01:00
Prognostic value of pre-operative left atrial strain on composite endpoint in patients received aortic valve replacement for severe aortic stenosis: a retrospective cohort study - Tsui L, Yiu K, Tse H, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.ObjectiveSevere aortic stenosis (AS) is the most common primary valvular heart disease, treatable only by aortic valve replacement (AVR). Current literatures have shown that severe AS may precede atrial dysfunction which predicts (...)
01:00
Hemodynamic change in patients with hypertrophic obstructive cardiomyopathy before and after alcohol septal ablation using 4D flow magnetic resonance imaging: a retrospective observational study - Suwa K, Akita K, Iguchi K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Ministry of Education, Science, Sports and Culture of Japan, Grants-in-Aid for Scientific ResearchBackgroundThe hemodynamics in the left ventricle (LV) and the ascending aorta (...)
01:00
Bridging to warfarin with apixaban versus conventional heparin: an open label, pilot, randomized controlled trial - Dangploy T, Wongvipaporn C. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Other. Main funding source(s): Queen Sirikit Heart center of the Northeast of ThailandBackground : Despite of non-vitamin K antagonist oral anticoagulants (NOACs) is a preferred oral anticoagulant but in limited-resource country, warfarin (...)
01:00
Prediction of in-hospital mortality by using get with the guideline-heart failure (GWTG-HF) risk scores in patients hospitalized with heart failure - Mahmood M, Banerjee S. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): University Grants Commission BangladeshBackgroundPrognostic stratification using readily available clinical data can assist clinical decision making in heart failure. Get with (...)
01:00
Incidence, clinical correlates and associated outcomes of dementia in heart failure: a population-based cohort study - Ren Q, Teng T, Wang T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundDementia, in the setting of heart failure (HF), portends poorer outcomes and poses great challenges in its clinical management.PurposeWe investigated the incidence, types, clinical correlates, and the prognostic impact of (...)
01:00
A single-centre analysis of in-stent restenosis after left main stenting - Jariwala P, Jadhav K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundPercutaneous coronary interventions (PCI) can be the standard of care for left main (LM) coronary artery disease. In-stent restenosis (ISR) is a rare complication and is associated with patient- and procedure-specific (...)
01:00
Aspirin vs. Clopidogrel as a Chronic maintenance monotherapy after PCI in patients with high ischemic risk and high bleeding risk: Subgroup analysis of the HOST-EXAM trial - Park K, Kang J, Koo B, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfon behalf of the HOST-EXAM investigatorsBackgroundThe HOST-EXAM randomized clinical trial recently performed a comparison of clopidogrel monotherapy vs. aspirin monotherapy in patients requiring indefinite antiplatelet (...)
01:00
Relationship of mean platelet volume to severity of coronary atherosclerosis in non-ST-segment myocardial infarction - Bin Waleed K, Tse G, Wang L, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundPlatelets play a crucial role in thrombotic mechanism. Mean platelet volume (MPV) is primarily indicator of platelet activation and its measurement is easy and time-effective. The MPV is associated with adverse cardiac (...)
01:00
Short- and long-term outcomes in patients with right ventricular infarction according to modalities of reperfusion strategies in China: data from China Acute Myocardial Infarction (CAMI) Registry - Mengjin H, Yuejin Y, Xiaojin G. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Twelfth Five-Year Planning Project of the Scientific and Technological Department of ChinaPurpose We sought to investigate the short- and long-term outcomes in patients with (...)
01:00
Clinical manifestation of coronary pulmonary arterial fistula diagnosed by cardiac computed tomography - Funabashi N, Kobayashi Y. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Coronary pulmonary arterial fistula (CPAF) may cause enlargement of an aneurysm, which may rupture or compress other organs, or occurrence of steal phenomenon of coronary arterial (CA) blood flow. We hypothesize that there (...)
01:00
Risk stratification and prognosis in pulmonary arterial hypertension: the Singapore experience - Teoh J, Yap J, Ong Z, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Aims & Background: Guidelines recommend the risk stratification of patients with pulmonary arterial hypertension (PAH) at baseline and on follow-up, so as to guide the management and titration of therapy in these patients. This (...)
01:00
Intravenous epoprostenol therapy in the treatment of pulmonary arterial hypertension: the Singapore experience - Choo J, Yap J, Ismail A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundPulmonary arterial hypertension (PAH) is a progressive disease with significant morbidity and mortality. While intravenous (IV) Epoprostenol, a prostacyclin analogue, has been shown to improve exercise tolerance, symptoms, (...)
01:00
The association between neutrophil to lymphocyte ratio and echocardiographic parameters in hospitalised adults with COVID-19 - a retrospective analysis - Agarwal R, Priyonugroho G, Hertine S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe neutrophil to lymphocyte ratio (NLR) is an inflammatory biomarker with prognostic value in several cardiovascular conditions. Hyperinflammation contributes to severe coronavirus disease 2019 (COVID-19), which is (...)
01:00
Correlation of cardiac biomarkers with computed tomography severity score in COVID-19 patients - Rivera R, Cuenza L, Razon-Cuenza T. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.INTRODUCTIONA vast number of COVID-19 cases have been reported worldwide since the initial outbreak in China, and the disease has since become a global pandemic. Knowledge on this predominantly respiratory illness is evolving with (...)
01:00
Learning curve of visually-guided laser balloon ablation of paroxysmal atrial fibrillation - Kondo Y, Nakano M, Kajiyama T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe visually-guided laser balloon (VGLB) is a compliant, variable-diameter balloon that delivers laser energy around the pulmonary vein (PV) ostium under real-time endoscopic visualization. However, limited data exist in (...)
01:00
Alternative method of adenosine administration in paroxysmal supraventricular tachycardia - Tangsuwanaruk T, Daengbubpha P, Wittayachamnankul B, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public Institution(s). Main funding source(s): Faculty of Medicine, Chiang Mai University Research FundBackgroundAn intravenous adenosine with a double syringe technique is an essential treatment in a patient with paroxysmal (...)
01:00
J waves reaching to equal or more than 2 of 3 LV inferior wall leads may predict the presence of organized myocardial fibrotic or fat change in survivors of ventricular fibrillation - Funabashi N, Kobayashi Y. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe distribution of J waves and the presence of organized left ventricular (LV) myocardial damage may be related in survivors of ventricular fibrillation (VF).PurposeTo predict the presence of organized myocardial damage (...)
01:00
Comparison of sites of wall thickening and abnormal late enhancement on cardiac CT and magnetic resonance imaging with electrocardiography findings in patients with confirmed cardiac amyloidosis - Funabashi N, Kobayashi Y. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundLeft ventricular (LV) wall thickening and diastolic dysfunction on a transthoracic echocardiogram (TTE) without a high voltage R wave on V5 leads on an ECG leads to a diagnosis of cardiac amyloidosis. A final diagnosis is (...)
01:00
Implication of current ASE/EACVI left ventricular diastolic function classification in predicting 2-year MACE in asymptomatic patients with diabetes and hypertension - Foo D, Lam K, Igo M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Ministry of Health MalaysiaBackgroundLeft ventricular diastolic dysfunction (LVDD) has been shown to be more prevalent in patients with diabetes, and once progress to overt (...)
01:00
Left main coronary artery dimension and variation in Thai population - Siriwiwattana T. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Objectives The aim of our study was to determine the length, proximal and distal dimension of the left main coronary artery (LMCA) in Thai population with normal LMCA, from coronary computed tomography angiography (...)
01:00
Identification of hemodynamically significant coronary artery disease with stress myocardial blood flow ratio by dynamic CT perfusion studies - Maqsood H, Ashraf T, Younus S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionCoronary computed tomographic angiography (CTA) is an accepted noninvasive tool with high diagnostic accuracy for the evaluation of coronary artery disease (CAD). However, coronary CTA is limited in that it does not (...)
01:00
Characterizing patients with newly diagnosed atrial fibrillation compared to those with established atrial fibrillation: data from the CODE-AF registry - Choi J, Lee S, Choi E. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Foundation. Main funding source(s): Korean Healthcare Technology R&D project funded by the Ministry of Health & WelfareOnBehalfCODE-AF investigatorBackground/Introduction: The characteristic of atrial fibrillation (AF), such as (...)
01:00
The impact of socioeconomic deprivation on the risk of atrial fibrillation in patients with diabetes mellitus: a nationwide population-based study - Han M, Lee S, Choi E, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundAlthough the prevalence of atrial fibrillation (AF) is increasing worldwide, little is known about the exact risk factors of AF; and the disease"s association with socioeconomic status (SES) is under debate.PurposeThis (...)
01:00
A short and long-term outcomes of heart failure with midrange and preserved ejection fraction; developing countries perspective - Leesutipornchai T, Puwanant S, Siwamogsatham S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundHospitalization and mortality are common among patients with heart failure (HF). However, evidence of outcomes in HF patients classified by left ejection fraction (LVEF) is limited, especially in Thailand.MethodsThis is a (...)
01:00
Chronic kidney disease begets heart failure and vice versa; temporal associations between heart failure events in relation to incident chronic kidney disease - Wu M, Teng T, Tay W, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundDiabetes, chronic kidney disease (CKD) and heart failure (HF) are fast-growing causes of morbidity and mortality worldwide. Diabetes is an optimal model to study the inter-play of cardiovascular disease and renal (...)
01:00
MicroRNA 155:145 ratio as a marker of atherogenic tilt manifested across different age groups and risk factor profiles - Banerjee A, Roy D, Mazumdar H, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Differential expression of microRNAs is critical in the genesis and progression of atherosclerosis. MiR145 has atheroprotective role through improved homeostasis of smooth muscle cells (SMC). MiR155 is pro-atherogenic due (...)
01:00
Association of Body mass index and clinical outcomes in patient with coronary artery disease undergoing percutaneous coronary intervention - Lin T, Leu H. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundMost of the world"s population lives in countries in which overweight status and obesity issues cause more morbidity and mortality than underweight status. Mortality increased as BMI increased above 25 kg/m², and the lowest (...)
01:00
Demographic analysis and clinical outcomes of COVID-19 and myocardial infarction from a tertiary care centre in south India - Kongara R, Sankaran R, Muralidharan T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Back ground – COVID-19 is reported in India from March 2020. It is known to cause myocarditis , arrythmias and heart failure. COVID-19 infection has been proposed to be associated with myocardial infarction.PURPOSE–We intent to study (...)
01:00
Comparison of VWF-ADAMTS13 axis involvement in atrial fibrillation and sinus rhythm in patients with ST-elevation myocardial infarction - Osawa T, Ito Y, Nakano K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Previous studies have shown that von Willebrand factor (VWF) increases, and a disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) decreases in myocardial infarction. Few studies have (...)
01:00
Risk scores in predicting adverse events after an acute coronary syndrome - Duarte F, Barradas M, Barradas M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionST-segment elevation myocardial infarction (STEMI) is a serious event that usually occur in patients with cardiovascular risk factors and is associated with great morbidity and mortality.PARIS ischemic risk score and TIMI (...)
01:00
Hemorrhagic risk scores in hospitalized patients with acute coronary syndrome: can they (only) predict bleeding events? - Duarte F, Barradas M, Oliveira L, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionAcute coronary syndrome (ACS) is a life-threatening condition and its therapeutic approach increases the risk of important bleeding events which are associated with a worse prognosis. Along with hemorrhagic events, a drop (...)
01:00
Standardized LocSSIPs improves risk prevention for in-patient angioplasty in tertiary care hospital - Kyaw K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfacute cardiovascular careIntroductionThere are no established ESC/NICE guidelines for acceptable Safety Checklists in invasive coronary angiogram. A lack of Quality Assurance Checklists that is indicated by WHO guidelines for (...)
01:00
Anatomical obstacles and their impact on the sheath to balloon time while intervening through a trans-radial approach in patients undergoing primary percutaneous coronary intervention - Kumar D, Abdul Bari S, Saghir T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundTrans-radial approach has been considered a safe and useful vascular access site for cardiac catheterization in comparison with the conventional trans-femoral approach. However, radial access has many challenges, such as (...)
01:00
Randomized comparison of proximal and distal radial access for coronary angiography and interventions - Dadarwal A, Garg N, Kapoor A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionVascular access for coronary procedures is of paramount important not only for successful procedure but also to prevent complications. In comparison to femoral access, proximal radial artery (PRA) access at wrist is (...)
01:00
Optical coherence tomography versus angiography to guide percutaneous intervention: a real-world single center propensity-matched analysis - Dadarwal A, Roy S, Sharma A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundOptical coherence tomography (OCT) with its superior resolution has several benefits over coronary angiography (CA) to guide percutaneous coronary intervention (PCI). Despite the benefits of OCT in comparison with (...)
01:00
ECG changes in psychiatric patients on psychotropic medications - Wong S, Soliman M, Cunningham A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundSuicide and euthanasia accounts for 14.3% of deaths in those with psychiatric conditions. The rest are attributed to preventable causes such as cardiovascular disease, respiratory disease, and infections. Several (...)
01:00
Efficacy and safety of fondaparinux versus unfractionated heparin in patients hospitalised with severe COVID-19 pneumonia and coagulopathy: a randomised, open-label clinical trial - Adrian L, Hutomo S, Negari A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): Syarifah Ambami Rato Ebu General Hospital, Bangkalan, East Java, IndonesiaBackgroundThe use of unfractionated heparin (UFH) has been renowned to reduce mortality in COVID-19. There are no data (...)
01:00
How to bridge residual distance to target low-density-lipoprotein cholesterol in acute coronary syndrome patients after initial statin therapy? - Yan B, Lai A, Sun H. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BACKGROUNDCurrent guidelines recommend intensive low-density-lipoprotein cholesterol (LDL-C) lowering by ?50% to target LDL-C PURPOSEWe aimed to evaluate residual distance to guideline recommended target LDL-C and the proportion of (...)
01:00
Pharmacological evaluation of the use of dexrazoxane in preventing anthracycline induced cardiotoxicity in breast cancer - Maqsood H, Ashraf T, Younus S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundAnthracyclines and trastuzumab are extensively used for the treatment of breast cancer but are associated with an increased risk of dilated cardiomyopathy. Dexrazoxane is an iron-chelating agent used to reduce the risk of (...)
01:00
In patients with paroxysmal atrial fibrillation left atrial strain paramethers, left atrial function index and poor glycaemic control can be predictors of arrhythmia recurrence - Rus H, Bobescu E, Poinareanu I. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionLeft atrial (LA) systolic dysfunction is present in early stages of atrial fibrillation (AFib) prior to left anatomical changes and is influenced by left ventricular systolic function. We evaluate weather left atrial (...)
01:00
Outcomes of cardiac CT investigations in patients from the Rapid Access Chest Pain clinic with consideration to additional CT modalities and individual risk factors - Juffry L, Lim F, Ahmad S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Coronary CT is a first line investigation according to NICE guidelines, yet there are still uncertainties in its ability to decrease adverse event rates. The high sensitivity and high negative predictive value of coronary CT only (...)
01:00
A fourteen-year experience on treatment of atrial fibrillation with radiofrequency ablation in Thailand: a real-world report from South East Asia - Tokavanich N, Leelapatana P, Chokesuwattanaskul R, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundAtrial Fibrillation ablation has been performed for more than 10 years, but the result of the procedure varied across centers. In Western world freedom from AF after ablation with PVI technique was 81.6% at 12 months, 73.8% (...)
01:00
Impact of heart rate reduction on recurrence after catheter ablation of persistent atrial fibrillation - Okada M, Inoue K, Tanaka N, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Private company. Main funding source(s): Johnson & Johnson KKOnBehalfOCVC Arrhythmia InvestigatorsBackgroundPredicting heart rate (HR) after restoration of sinus rhythm (SR) remains one of the challenges when performing catheter (...)
01:00
Validation of HAS-BELD scoring system and risk factors of bleeding with warfarin among non-valvular atrial fibrillation patients - Wachirapraditporn P, Uaprasert N. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.ObjectivesThis study aimed to validate different bleeding scoring systems including HAS-BELD score and other scores and risks of bleeding in Thai patients with non-valvular atrial fibrillation (AF).BackgroundAF is the most common (...)
01:00
Cardiorenal effects of SGLT2i in combination with ARNI for HFrEF: a systematic review and meta-analysis - Cordovez R, Rivera K, Denila R, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundRecent recommendations suggest a combination of Angiotensin receptor neprilysin inhibitor (ARNI) and beta blocker with other classes of medications in heart failure with reduced ejection fraction (HFrEF) (1). Despite (...)
01:00
Pulmonary artery pulsatility index and hemolysis during Impella support - Nakamura M, Imamura T, Kinugawa K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundImpella-related hemolysis is a well-known complication, which we sometimes experience in the clinical practice depending on various hemodynamic status including right ventricular impairment.MethodsWe enrolled consecutive (...)
01:00
The correlation between coronary artery disease and left ventricular filling pressure: which correlates more LVEDP or LV pre-A wave? - Barakat A, Amar A, Alsaadi A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): Al-mouwasat University Hospital and Uneversity Heart Surgery Center, Damascus, Syrian Arab Republic.BackgroundCoronary artery disease (CAD) affects left ventricular (LV) systolic and diastolic (...)
01:00
The value of microRNA-122 in the diagnosis of coronary heart disease - Marchenko O, Rudenko N, Kyriachenko Y, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background. Patients with ischemic heart diseases form the majority group of cardiac diseases. Studies on the roles and mechanisms of microRNAs taking part in cardiac pathophysiology have become the focus of research (...)
01:00
Prognostic value of GRACE versus TIMI Score for in-hospital outcomes after non-ST-Elevation acute coronary syndrome - Kumar D, Saghir T, Ahmed Khan K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe risk stratification scores are very helpful to categorize high risk patients to plan future management. Therefore, in this study we compared the predictive value of TIMI and GRACE score for predicting in-hospital (...)
01:00
Impact of SARS-CoV2 pandemic onto acute ST-elevation myocardial infarction care and patient outcomes in a large tertiary cardiac center - Yong D, Sulong M, Sundarajoo M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundSARS-CoV2 pandemic has caused major impact on patient care worldwide. We experienced a surge of cases beginning March 2020 leading to the government imposing a movement control order, more commonly known as ‘lockdown’ (...)
01:00
Clinical manifestation and impact on management of acute coronary syndrome during covid-19 pandemic, lessons learnt from a tertiary care - Subburaja T, Sambasivam K, Radhika R, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionThe World Health Organization first characterized COVID-19 as a ongoing pandemic since 12th March 2020. Since then, mitigation plans including vaccinations are on the run globally. During this pandemic several (...)
01:00
Optimal landmark for chest compression during cardiopulmonary resuscitation derived from a chest computed tomography in arms-down position - Usawasuraiin P, Wittayachamnankul B, Euathrongchit J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Private hospital(s). Main funding source(s): The Faculty of Medicine, Chiang Mai University FundBackgroundRecently evidence, compression at the maximal left ventricular diameter on sternum (LVmax) maximises cardiac output, stroke volume (...)
01:00
Platinum chromium everolimus-eluting stent versus cobalt chromium zotarolimus-eluting stent in very late stent thrombosis: a meta-analysis of randomized controlled trials - Baterna J, Susanto A, Cheng F. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionVery late stent thrombosis is a rare but potentially lethal outcome for drug-eluting stents used in percutaneous coronary intervention. There is limited research currently on the occurrence of very late stent thrombosis (...)
01:00
Refined balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: a prospective multicenter registry - Zhou Y, Wei Y, Yang Y, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Foundation. Main funding source(s): the National Key Research and Development Program of ChinaBackground Chronic thromboembolic pulmonary hypertension (CTEPH) is a life-threatening disease with a poor prognosis if left untreated. (...)
01:00
Transit time flow measurement (TTFM) as a predictor of graft failure and major adverse cardiac events following coronary artery bypass grafting (CABG) - Yong H, Lim M, Kok K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionPost coronary artery bypass grafting (CABG), coronary angiography (CAG) is the gold standard for graft assessment to check the presence of occlusion or stenosis. Despite this, CAGs after a CABG in the nation are only (...)
01:00
The association of preoperative dialysis with troponin trends and short term outcomes among advanced kidney disease patients undergoing coronary artery bypass grafting - Manla Y, Hogan M, Bhatnagar G, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionCoronary artery disease continues to be the leading cause of death in patients with stage IV-V chronic kidney disease (CKD IV-V). However, the prognosis and early outcomes for advanced CKD patients undergoing coronary (...)
01:00
Evaluation of subclinical LV systolic dysfunction by global longitudinal strain using 2D-speckle tracking echocardiography in patients having angina with normal epicardial coronary arteries - Hoque M, Ahmed C, Osmany D, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Other. Main funding source(s): SelfBackground Global longitudinal strain (GLS), assessed by 2D speckle tracking echocardiography would be a trustworthy noninvasive tool to detect subclinical LV systolic dysfunction in patients having (...)
01:00
Prevalence and distribution of coronary artery calcium in a southeast asian cohort - Wong C, Choo H, Baskaran L, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe coronary artery calcium score (CACS) independently predicts the risk of cardiovascular disease and major adverse cardiovascular events. While previous studies have demonstrated regional and ethnic differences in (...)
01:00
High sensitivity C-reactive protein is associated with vulnerable characteristics in non-culprit plaques in patients with ST-segment elevation myocardial infarction - Katamine M, Minami Y, Nagata T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundHigher level of high sensitivity C-reactive protein (hsCRP) is associated with an increased risk of recurrent cardiovascular events in patients with ST-segment elevation myocardial infarction (STEMI). However, the (...)
01:00
The role of STEMI integrated networking system based on tele-cardiology for reducing ischemic time and crossing wire time delayed during COVID 19 pandemic - Rizki Fadlan M, Anjarwani S, Saifur Rohman M. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfon behalf of contributors for Saiful Anwar Hospital Acute Coronary Syndrome Pre Hospital NetworkBackground During a public health emergency, such as outbreak of COVID-19, delayed for reperfusion become even more challenging (...)
01:00
Association of body mass index with systolic and diastolic blood pressure in rural Indians - Inamdar A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundBody mass index (BMI) is positively and independently associated with morbidity and mortality from hypertension, cardiovascular disease, type II diabetes mellitus, and other chronic diseases. In Caucasian and Asian (...)
01:00
Impact of the COVID-19 pandemic on cardiology services in the second year at a South Asian cardiac centre - Cader F, Haq M, Khan S. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundLittle has been reported on the impact of the COVID-19 pandemic and the new delta variant, on cardiology services and catheterization volumes in South Asia, during the second year of the pandemic.PurposeWe aimed to assess (...)
01:00
Thromboembolic complication among COVID-19 patients in the intensive care unit (ICU): a single-centre study from a Malaysian perspective - Zulkifly H, Mansor F, Abdul Halim Zaki I, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionThe emerging complications of thromboembolism (TE) in COVID-19 patients have led to severe consequence such as death. Nonetheless, the prevalence of TE complications among COVID-19 patients in the Intensive Care Unit (...)
01:00
Measuring the arterial phase of the right coronary artery in the patients suspected of coronary artery disease: a dual study by dynamic angiography and deep learning program - Truyen T, Vu L, Pham D, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background. In the diagnosis of coronary artery disease (CAD), coronary angiography (CA) plays a crucial role in determining the location and severity of the stenosis, the anatomical aspect of a lesion. It does not accurately reflect (...)
01:00
The correlation of ESC 2016 diastolic guidelines with invasively measured left ventricular filling pressure - Barakat A, Amar A, Alsaadi A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): Al-mouwasat University Hospital, University Heart Surgery Center in Damascus, Syrian Arab Republic.Backgroundleft ventricular (LV) diastolic function and filling pressure assessment is a (...)
01:00
The Clinical Experience of Macitentan in pulmonary hypertension in Indian cohort: 12-months follow-up - Jariwala P, Jadhav K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.AIM AND OBJECTIVEMacitentan, an endothelin receptor antagonist, has been shown to be effective and safe in the treatment of pulmonary arterial hypertension (PAH) in multiple randomized clinical trials, including SERAPHIN, focusing on (...)
01:00
Effectiveness and safety of combined direct oral anticoagulant and antiplatelet among high-risk peripheral arterial disease: a meta-analysis - Solano S, Obrado G, Balcos K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundPeripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis which strongly correlates to cardiovascular morbidity and mortality and increased risk of limb loss, and despite the wide use of (...)
01:00
High visit-to-visit cholesterol variability predicts new-onset heart failure and adverse cardiovascular events: a retrospective population-based cohort study - Chan J, Zhou J, Satti D, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundHyperlipidaemia is associated with adverse cardiovascular outcomes. However, the long-term prognostic value of visit-to-visit cholesterol variability is less certain, particularly regarding the risks of new-onset heart (...)
01:00
Can cord blood lipid and lipoprotein levels inform LDL targets? - Tan J, Yeo K, Phua S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Introduction Current ESC dyslipidemia guidelines recommend lowering LDL targets to 1.4mmol/L (55mg/dL) for very high risk individuals. Lipid levels of newborns may provide insights into physiologic levels at the time of birth. There (...)
01:00
Normal weight central obesity among Filipinos and its association with cardiovascular diseases: a cross-sectional study - Toledano B, Yap E, Vilela G. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public Institution(s). Main funding source(s): Philippine Lipid Atherosclerotic SocietyBackgroundNormal weight central obesity reflects an increased visceral fat and low lean mass hence its association with cardiovascular (...)
01:00
Palliative care for patients with cardiovascular disease and COVID-19 in a major referral hospital - Correa T, Simao A, Sobreira J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionCOVID-19 disease has a wide spectrum of severity, ranging from asymptomatic to severe acute respiratory syndrome. Although the estimated mortality is around 3% in the general population, individuals with comorbidities (...)
01:00
The effect of high intensity interval training on patients with heart transplantation: a systematic review - Rajandekar T, John G. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BACKGROUNDExercise rehabilitation after heart transplant is of major importance in order to improve physical capacity and prognosis.High-intensity interval training (HIIT) has repeatedly proven to be a highly efficient form of (...)
01:00
Differing radiation exposure in scrub technicians and rotating staff in cardiac catheterization laboratory: occupation matters - Javed M, Rahman N, Adnan G, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundRadiation exposure of cardiac catheterization lab personnel is an evolving area of concern, due to long term, repetitive exposure causing deterministic and stochastic effects(1,2). Current radiation protection measures are (...)
01:00
AEPEI scoring system to predict mortality among patients diagnosed with infective endocarditis after surgery at the philippine heart center: a retrospective analytical cross-sectional study - Gatuz M, Cuenza L. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Infective endocarditis (IE) is a life-threatening disease which continues to pose significant challenges in clinical practice. Surgery for IE while curative can be associated with considerable morbidity and mortality. We (...)
01:00
Symptomatology, prognosis and clinical findings of myocarditis as an adverse event of COVID-19 mRNA vaccine: a systematic review - Jaiswal V, Jaiswal A, Batra N, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundMyocarditis, an inflammation of the myocardium in the absence of ischemic injury, may be caused by viruses, drugs, and vaccines. The Myocarditis following COVID-19 vaccinations is most commonly seen in young adult males and (...)
01:00
Prevalence and predictors for high blood pressure during covid-19 vaccination in Thailand - Patamatamkul S. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe Thai government mandates BP measurement prior to COVID-19 vaccination to ensure safety for all vaccinees. However, there is neither large study regarding the prevalence of high BP nor CV complication during COVID-19 (...)
01:00
Evaluation of outcome of Coronavirus disease 2019 patients receiving RAAS inhibitors (OCRAS study): a prospective observational study of Bangladeshi hypertensive patients - Majumder A, Rahman M, Islam A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Private company. Main funding source(s): Beximco Pharmaceutical Limited, BangladeshOnBehalfCardiology Study Group (Bangladesh)BackgroundThe fact that SAARS-Cov2 virus enters cells through ACE2 receptors and the (...)
01:00
Blood pressure variability in hypertension patients in Indian clinical settings - Abhyankar M, Jinghan A, Das C, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Blood pressure variability (BPV) is a potential predictor for complications such as coronary artery disease, heart failure, stroke, and all-cause death, independently of mean blood pressure (BP) in patients with (...)
01:00
The safety and efficacy of efonidipine, an L- and T-Type dual calcium channel blocker, on heart rate and blood pressure in indian patients with mild-to-moderate essential hypertension - Jariwala P, Jadhav K. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundEfonidipine hydrochloride, an L- and T-type dual calcium channel blocker, have a heart rate (HR)-slowing action in addition to a blood pressure (BP)-lowering effect. Many younger Indian hypertensive patients has sinus (...)
01:00
Can paraoxonase activity serve as a comparable marker than high density lipoprotein in the follow-up of patients of coronary artery disease? - Chatterjee S, Majumder B, Biswas P, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundHuman serum paraoxonase (PON1) produced by the liver and residing almost exclusively on high density lipoproteins (HDL), has been demonstrated to prevent the oxidation of low density lipoprotein (LDL), which is the central (...)
01:00
Role of myocardial performance index as predictor of in-hospital cardiac events in patients with acute myocardial infarction - Dalimunthe N. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background. Acute myocardial infarction (AMI) remains the leading cause of morbidity and mortality worldwide. Left ventricular dysfunction is a common consequence of acute coronary events and has important prognostic implications. (...)
01:00
Influence of ST2 level on the development of acute arrhythmias in NSTEMI - Maslovskyi V, Mezhiievska I. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.PurposeTo determine the structure and relationship of cardiac arrhythmias in NSTEMI patients based on plasma ST2 level.MethodsWe studied 90 patients with NSTEMI aged from 35 to 79 years (mean 60.7 ± 0.8, median - 61, interquartile (...)
01:00
Coronary atherosclerotic burden and trimethylamine N-oxide in non-ST-segment myocardial infarction patients: SZ-NSTEMI cohort - Bin Waleed K, Wang L, Chang J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundTrimethylamine N-oxide (TMAO) is reported to accelerate atherosclerosis and adverse cardiac outcomes. Relationship between coronary atherosclerotic burden and TMAO has linked in stable coronary artery disease and ST-segment (...)
01:00
Performance and 12 month outcomes of a wire free fractional flow reserve system for assessment of coronary artery disease, first experience in south east asia - Bhavnani C, Fong A, Koh K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundFractional flow reserve (FFR) using an invasive pressure wire has a Class 1A recommendation for guiding coronary revascularization in stable coronary artery disease (CAD). Angiography based ‘wire free’ FFR is an emerging (...)
01:00
Three year clinical outcomes of fractional flow reserve guided coronary revascularization using a monorail pressure sensor microcatheter - Bhavnani C, Koh K, Oon Y, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundFractional flow reserve (FFR) has a Class 1A recommendation for guiding coronary revascularization in stable coronary artery disease. Deferral of revascularization for coronary stenosis of FFR >0.80 has shown favorable (...)
01:00
Instantaneous wave-free ratio and fractional flow reserve: effect of variation in left ventricular end diastolic pressure - Sharma P, Vohra S, Bhandari M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionAmong patients with intermediate coronary artery stenosis (50-90%), assessment of functional significance of the lesion by instantaneous wave free ratio (iFR)/ fractional flow reserve (FFR) is recommended in latest (...)
01:00
Safety and efficacy of percutaneous coronary interventions performed via anatomical snuffbox access in elderly patients - Berezhnoi K, Vanyukov A, Kokov L. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundRadial artery thrombosis is a potential complication of transradial catheterization. For elderly patients greater attention should be paid to preserve radial arteries due to rather common comorbidities, such as renal (...)
01:00
A four year experience of peripartum cardiomyopathy in a rural public hospital in south india - Kanakasabapathy R, Annamalai N. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionPeripartum cardiomyopathy (PPCM), as defined by the study group on PPCM of Heart Failure Association of the European Society of Cardiology (ESC), is an idiopathic Cardiomyopathy with systolic heart failure occurring (...)
01:00
Comorbidity and quality of life in older patients with chronic cardiorenal syndrome and obstructive sleep apnea - Efremova E, Shutov A, Serov V, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Comorbidity increases with age, including the presence of cardiovascular disease, chronic kidney disease (CKD) and obstructive sleep apnea (OSA). OSA is considered as a risk factor for the progression of CKD.The aim of this study was (...)
01:00
Awareness and cognitive status of older patients with chronic cardiorenal syndrome in terms of patient-centered approach - Efremova E, Shutov A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.A patient-centered approach is the basis for older patients with cardiovascular comorbidity. Collaborative decision making is especially important for older patients with chronic kidney disease (?KD).The aim of the study was to study (...)
01:00
Prognostic indicators for the onset of ischaemic versus haemorrhagic stroke in stable coronary artery disease - Wang W. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background The incidence of stroke may be increased in patients with coronary artery disease (CAD). We aimed to investigate the specific risk factors for the development of ischaemic and haemorrhagic stroke in stable CAD (...)
01:00
The diagnostic value of different criteria in predicting the response of LBBB patients: a systematic review and meta-analysis - Peng X, Cheng C, Zeng L. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background The left bundle branch has emerged as an essential part of the cardiac conduction system. However, many patients with conventional left bundle branch block (LBBB) QRS morphology appeared to have a poor response to cardiac (...)
01:00
The first survey on patient needs for remote monitoring of cardiac implantable electronic device in South Korea - Hwang Y. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background/Aims: Studies showed that remote device monitoring reduced unnecessary outpatient visits and increased patient satisfaction. As there was no local research on remote monitoring (RM) in Korea, there was a lack of evidence (...)
01:00
GDF-15: a novel biomarker of heart failure predicts 30-day all-cause mortality and 30-day HF rehospitalization in patients with acute heart failure syndrome - Kosum P, Mattanapojanat N, Kongruttanachok N, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public hospital(s). Main funding source(s): Ratchadapiseksomphotch Fund, Faculty of Medicine, Chulalongkorn UniversityBackgroundGrowth Differentiation Factor-15 (GDF-15) is a distant member of the transforming growth factor-? (TGF-?) (...)
01:00
Development and validation of gender specific risk models in prediction of mortality for hospitalized heart failure patients in a multiethnic asian population - Quah W, Sulong M, Koh H, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background/IntroductionHeart failure carries substantial morbidity and mortality. Female has different characteristics compared to male which may affect prognosis and are not represented well in many trials. Multiple risk scores for (...)
01:00
Spontaneous coronary artery dissection - case series of a rare disease - Hashmani S, Garrod R, Shamsi F, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundSpontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome (ACS) particularly in young women. Female sex, pregnancy, emotional stress and fibromuscular dysplasia are known triggering (...)
01:00
Liver stiffness assessed by Fibrosis-4 index predicts heart failure in AMI patients - Nunohiro T, Furukawa K, Uchida M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.It has been recently reported that the liver stiffness, which reflects increased central venous pressure, measured by transient elastography increases along with decompensated heart failure (HF) developing and decreases with clinical (...)
01:00
Arrhythmogenic right ventricular cardiomyopathy patients with a markedly enlarged RV compressing LV to left side have an atypical distribution of epsilon waves and elevated plasma BNP - Funabashi N, Okamoto M, Nakamura K, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundEpsilon waves on V1-3 leads are specific ECG findings in patients with arrhythmogenic right ventricular (RV) cardiomyopathy (ARVC) suggesting RV conduction delay. Four dimensional (4D) cardiac CT visualizes ARVC (...)
01:00
Predictions of arrhythmic, heart failure and mortality outcomes in pericarditis using automatic electrocardiogram analysis: a retrospective cohort study - Lakhani I, Zhou J, Li A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Introduction Pericarditis is a relatively rare disease with a global burden. Despite its strong association with adverse cardiovascular outcomes, identification of patients at risk of future heart failure or arrhythmic events is (...)
01:00
Pericardiocentesis over 3 years at a tertiary referral Australian hospital - Ramachandran J, Pender P, Assad J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Pericardiocentesis is a lifesaving intervention performed both percutaneously or surgically. We analysed 3 years of experience in a major tertiary hospital in Sydney Australia. Purpose To examine the indications, safety (...)
01:00
Diagnostic delay in congenital heart disease related pulmonary arterial hypertension: insights from the single tertiary hospital center of pulmonary hypertension registry in East-Java Indonesia - Icmi Dian Rochmawati I, Muhamad Rizki Fadlan F, Heny Martini H. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundCHD-Pulmonary arterial hypertension (PAH) is a progressive and fatal disorder. There could be more severe, permanent pathological changes and right ventricular failure in patients diagnosed in later stages, contributing to (...)
01:00
Sex-specific differences in mortality after first time, isolated coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized controlled trials - Matthews S, O"neil A, Sanders J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BACKGROUNDEvidence quantifying sex-specific differences in cardiac surgical outcomes is scant.PURPOSEThe purpose of this review was to determine whether contemporary evidence indicates Coronary Artery Bypass Graft Surgery (CABGS) is (...)
01:00
Early impact of COVID-19 pandemic on heart transplant volumes in Asia and Oceania: results from the Global Observatory on Donation and Transplantation (GODT) - Manla Y, Bader N, Bajwa G, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionMassive demand for healthcare services worldwide following the emergence of coronavirus disease 2019 (COVID-19) has limited the availability of healthcare resources needed for certain high-complexity procedures, including (...)
01:00
Effect of profilin-1 on the asymmetric dimethylarginine-induced vascular lesion associated hypertension - Ni G. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfGuohua NiObjectivePrevious studies have demonstrated that the levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthesis, are strongly associated with hypertension, diabetes, and (...)
01:00
The association between transthoracic echocardiographic parameters and severity of COVID-19 in hospitalised adults - a retrospective analysis - Agarwal R, Priyonugroho G, Hertine S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe coronavirus disease 2019 (COVID-19) is an ongoing global pandemic with more than 220 million cases and 4.5 million deaths reported worldwide. Its clinical spectrum varies widely, and non-invasive prognostic markers are (...)
01:00
Effects of hot balloon versus cryoballoon ablation for atrial fibrillation: a systematic review and meta-analysis - Peng X, Chen Y, Li X. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundCatheter ablation has developed as the most effective therapeutic approach and won the highest-level guideline recommendation in treating atrial fibrillation (AF) in the decades. Several balloon-based catheter ablations, (...)
01:00
Implantable cardioverter-defibrillators in heart transplant patients: a systematic review and meta-analysis - Cho K, Lo P, Subbiah R. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundWhilst implantable cardioverter-defibrillator (ICD) implantation is beneficial in a select group of patients, heart transplant patients were excluded from landmark clinical trials. Thus, controversy remains about the (...)
01:00
Machine learning based diagnosis of heart failure with preserved ejection fraction among South Asian patients - Cherukupalli R, Achanta A, Cherukupalli A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundDiagnosis of Heart Failure with preserved Ejection Fraction (HFpEF) remains challenging even for an astute clinician with the current diagnostic tests, algorithms and scoring systems. The use of Machine Learning (ML) in (...)
01:00
Molecular mechanism and therapeutic potential of YiQi FuMai injection in acute heart failure - Dai H, Li H, Zhang J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Foundation. Main funding source(s): The National Science Foundation for Distinguished Young Scholars of ChinaBackground Acute heart failure (AHF) is a significant public health problem related to the high mortality and rehospitalization (...)
01:00
Greater mitral valve area in obese patients with rheumatic heart disease: a new evidence of obesity paradox ? - Lestari A, Akbar M, Alie I. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BACKGROUND The existence of obesity paradox’s been proposed this past decade, suggesting obese individuals may have survival benefit when there"s acute cardiovascular decompensation or congestive heart failure. Adiponectin, a residual (...)
01:00
Prognostic implications of the proportionality of tricuspid regurgitation in tricuspid annuloplasty - Stephanie Y, Li H, Ren Q, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Patients with secondary tricuspid regurgitation (TR) represent a heterogeneous group that benefits differentially from tricuspid annuloplasty. We hypothesized that TR severity may be proportional or disproportional to (...)
01:00
Intravascular lithotripsy during percutaneous coronary intervention for calcified coronary lesions: analysis of patient and procedural characteristics and clinical outcomes - Leung J, Pender P, French J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background/IntroductionCoronary artery calcification is frequently encountered during percutaneous coronary intervention (PCI). It can reduce PCI success and increase intra-procedural and post-procedural complications, including (...)
01:00
Initial clinical experience with a new sheathless guiding catheter designed for direct insertion - Borrie A, Fairley S, Harding S. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundRadial access for percutaneous coronary intervention (PCI) is growing rapidly as this approach has been shown to improve patient comfort and reduce complications. Use of a sheathless guiding catheter for transradial PCI has (...)
01:00
Effectiveness of a home-based cardiovascular disease prevention program during the COVID-19 pandemic - Chockalingam P, Natarajan V, Sekar T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundHome-based cardiovascular disease (CVD) primary prevention (HBPP) and cardiac rehabilitation (HBCR) programs which occupied a small proportion of the overall Preventive Cardiology work in the past have become mainstream (...)
01:00
Referral rates and patient characteristics of the inpatient cardiac rehabilitation program of a philippine tertiary cardiovascular referral center - Agustin R, Samson A, Dela Cruz A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionInternational guidelines recommend effective cardiac rehabilitation programs to decrease mortality and morbidity and improve health-related quality of life. However, cardiac rehabilitation remains underutilized with low (...)
01:00
Correlation between fasting heart rate and fasting plasma glucose level in rural Indians - Inamdar A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionDiabetes mellitus is associated with abnormal autonomic function. Diabetes and impaired fasting glucose are associated with increased mortality, particularly from cardiovascular causes. Several factors, including fast (...)
01:00
Impact of perioperative interruption of antithrombotic therapy on thrombotic and bleeding events in non-cardiac surgery - Saito K, Saito Y, Muramatsu T, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionAntithrombotic therapy including antiplatelet agents and anticoagulants are prescribed for secondary prevention in patients with established cardiovascular disease. Although antithrombotic therapy is often interrupted (...)
01:00
Machine learning to predict in-hospital mortality risk among heterogenous STEMI patients with diabetes - Kasim S, Malek S, Aziz M, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): TECHNOLOGY DEVELOPMENT FUND 1BackgroundDiabetes has become a major public health concern in Asia. In Malaysia, the prevalence of diabetes has escalated in adults above the age (...)
01:00
Remission of T2DM by digital twin technology with reduction of cardiovascular risk: interim results of randomised controlled clinical trial - Shamanna P, Joshi S, Shah L, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Private company. Main funding source(s): TWIN HEALTH INCBackground Twin Precision Treatment (TPT) is a novel intervention designed to improve glycemia and reverse T2D using a Whole-Body Digital Twin (WBDT) platform powered by Artificial (...)
01:00
Impact of Covid-19 on cardiovascular clinics: are we ready for tele-medicine? - Mujtaba M, Sapna , Khanzada F, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundWorld is facing Coronavirus disease (COVID-19) pandemic since December 2019. [1, 2]. COVID-19 has significantly decreased the influx of patients presenting with cardiovascular diseases at hospitals. The aim of this study (...)
01:00
Virtual medical research mentoring and collaboration: breaking the bounds of nationality during the COVID-19 pandemic - Chan J, Lau D, King E, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.OnBehalfCardioovascular Analytics GroupBackgroundMedical research is critical to professional advancement, and mentoring is an important means of early research engagement in medical training. In contrast to international research (...)
01:00
Vascular inflammation in patients with obstructive sleep apnoea and coronary artery disease shown on coronary computed tomography angiography attenuation - Yuvaraj J, Cameron W, Andrews J, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionObstructive sleep apnoea (OSA) is associated with increased plaque burden in coronary artery disease (CAD), but the role of vascular inflammation in this relationship is unclear. Coronary computed tomography angiography (...)
01:00
Cost-effectiveness of apixaban versus other oral anticoagulants and aspirin for stroke prevention in atrial fibrillation in indian subcontinent - Kulkarni N, Taur S, Tichy E, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Private company. Main funding source(s): Pfizer LtdBackground/IntroductionNon-vitamin K antagonist oral anticoagulants (NOACs) are class I recommended by various guidelines for stroke prevention in atrial fibrillation. NOACs are (...)
01:00
Oral antithrombotic prescription patterns among hospitalized adult patients with non-valvular atrial fibrillation - Soco M, Junia A. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundOral anticoagulant (OAC) therapy reduces stroke risk in patients with atrial fibrillation. Despite extensive recommendations regarding the use of non-vitamin K antagonist oral anticoagulants (NOACs), available data shows (...)
01:00
Performance of anticoagulation risk scores for predicting ischaemic stroke in dialysis patients with atrial fibrillation - Liao Y, Wang T. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundRisk models such as the CHADS? and revised CHA?DS?-VASc scores are recommended for anticoagulation decision-making in atrial fibrillation (AF) patients. Despite this, their prognostic utilities in dialysis patients with AF are (...)
01:00
Impact of angiotensin-receptor neprilysin inhibitor on reverse cardiac remodeling in patients with heart failure with reduced ejection fraction (hfref) - Atan N, Loch A, Hadi F. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Cardiac remodeling is a detrimental consequence of heart failure. The angiotensin-receptor neprilysin inhibitor (ARNI) sacubitril/valsartan has been shown to reverse cardiac remodeling and to improve systolic function in (...)
01:00
Yield of surveillance endomyocardial biopsies after heart transplantation: a 10-year experience - Aekarach A, Sinphurmsukskul S, Siwamogsatham S, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundEndomyocardial biopsy (EMB) is recommended as a surveillance procedure for the detection of allograft rejection in all patients after heart transplant. However, the clinical yield of EMB is reported to be low and there are (...)
01:00
Association of aVR ST-elevation with outcomes in patients with acute coronary syndrome - Cordovez R. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionEvaluation of the lead aVR in the diagnosis of acute coronary syndrome has been neglected before.1 However, there is evidence that an ST segment elevation in that lead correlates to a significant coronary artery (...)
01:00
Predictors of elevated follow-up high sensitivity troponin after an initial normal value during acute exacerbations of chronic obstructive pulmonary disease - Yew M, Abisheganaden J, Xu H. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BACKGROUNDElevation of cardiac troponin (cTn) may be seen in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and is both diagnostic for myocardial injury and confers a poorer prognosis. Serial cTn testing after (...)
01:00
Smokers paradox in non-ST elevation acute coronary syndromes: does it exist? - Dakhil Z, Farhan H. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.IntroductionIn Iraq; about third of males and 4% of females are smokers. There is no data from Middle eastern countries including Iraq on impact of smoking on prognosis in ACSPurposeto assess if there is smokers? paradox in patients (...)
01:00
The potential beneficial effects of polysaccharide peptide on oxidative stress and lipid profile in post myocardial infarction patients: a double-blind, randomised controlled trial - Adrian L, Sargowo D, Sugita P. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Indonesia"s Ministry of Research and Technology grantsBackgroundInflammation, oxidative stress and lipid peroxidation activities contribute to the progression of (...)
01:00
P2Y12 pre-treatment for NSTE-ACS in a tertiary hospital centre: real world compliance experience with ESC 2020 guidelines - Kaul R, Khoo J, Pender P, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.BackgroundThe 2020 ESC guidelines for managing NSTE-ACS recommend against routine pre-treatment with a P2Y12 receptor inhibitor if coronary anatomy is not known and an early (24h) invasive management, pre-treatment may be considered (...)
01:00
Real world outcomes of Thai patient with acute coronary syndrome classified by achieved low-density lipoprotein level - Leesutipornchai T, Kunlamas Y, Areepium N, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: None.Background Although lower low-density lipoprotein (LDL) level is recommended to improves clinical outcomes, little is known about the association between LDL level after treatment and outcomes in developing countries. The aim of the (...)
01:00
The association of liver enzymes with systolic and diastolic blood pressure in young adults - Correa T, Freitas D, Brum C, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Science and Technology Department, Brazilian Ministry of Health.IntroductionNonalcoholic fatty liver (NAFLD) disease has been associated with metabolic syndrome and (...)
01:00
Impact of the anti-hypertensive diets virtual education towards knowledge, attitude, practice, and reduction of blood pressure during covid-19 pandemic - Andrianto A, Ardiana M, Yutha A, et al. Eur Heart J

AbstractFunding AcknowledgementsType of funding sources: Public grant(s) – National budget only. Main funding source(s): Universitas Airlangga Project Grants for Community EmpowermentOnBehalfUniversitas AirlanggaBackground. One of the efforts to reduce hypertension rates in the community is (...)

3 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Paradoxical enlargement of immunoglobulin G4 (IgG4)-related coronary aneurysms despite controlling serum IgG4 level - Takei Y, Abe N, Bohgaki M, et al. Eur Heart J

A 78-year-old man was presented with the productive cough to our hospital. A chest radiograph demonstrated the abnormal cardiac silhouettes, and the computed tomography (CT) revealed right and left circumflex coronary aneurysms with circumferential and periarterial soft-tissue enlargements (...)
01:00
Transcatheter lithotripsy to facilitate post-dilatation of underexpanded aortic transcatheter heart valve - Belluschi I, Buzzatti N, Denti P, et al. Eur Heart J

A 72-year-old male, with severely calcified bicuspid aortic stenosis, was treated with a transfemoral transcatheter aortic valve implantation (Evolut Pro 29 mm; Medtronic, USA) in another institution. Intraprocedurally, post-dilatation was unsuccessful to expand the (...)
01:00
Smart devices resulting in big effect: can apps cure heart disease?How hybrid care may revolutionize heart disease treatment - Eckardt I, Düsing P, Nickenig G, et al. Eur Heart J

Deutsche Forschungsgemeinschaft10.13039/501100001659JA 2351/2-1397484323Corona Foundation10.13039/100016021397484323
01:00
Sex-related differences in treatment and outcome of chronic limb-threatening ischaemia: a real-world cohort - Makowski L, Köppe J, Engelbertz C, et al. Eur Heart J

AbstractAimsThe prevalence of chronic limb-threatening ischaemia (CLTI) is increasing and available data often derive from cohorts with various selection criteria. In the present study, we included CLTI patients and studied sex-related differences in their risk profile, vascular procedures, and (...)
01:00
Impact of baseline renal dysfunction on cardiac outcomes and end-stage renal disease in heart failure patients with mitral regurgitation: the COAPT trial - Beohar N, Ailawadi G, Kotinkaduwa L, et al. Eur Heart J

AbstractAimsBaseline renal dysfunction (RD) adversely impacts outcomes among patients with heart failure (HF) and severe secondary mitral regurgitation (MR). Heart failure and MR, in turn, accelerate progression to end-stage renal disease (ESRD), worsening prognosis. We sought to determine the (...)
01:00
Coronary flow reserve: a versatile tool for interrogating pathophysiology, and a reliable marker of cardiovascular outcomes and mortality - Taqueti V. Eur Heart J
01:00
Treatment of heart failure across the spectrum of left ventricular ejection fraction and an update on cardiac amyloidosis and ischaemic cardiomyopathy - Crea F. Eur Heart J

1 February

Eur Heart J https://academic.oup.com/site_5375/

01:00
Isolated early peak cardiac troponin for clinical decision-making after elective cardiac surgery: useless at best Eur Heart J

31 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Cardio-oncology: a focus on cardiovascular toxicities of cancer therapies and on atrial fibrillation in cancer - Crea F. Eur Heart J

29 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Massive biventricular thrombosis after transfemoral transcatheter aortic valve implantation - Dregoesc M, Istrate M, Sandu I, et al. Eur Heart J

A 72-year-old lady was admitted for symptomatic severe low-flow low-gradient aortic stenosis. She had a history of chest radiation and bilateral mastectomy for invasive ductal carcinoma. The left ventricular (LV) volumes measured 182/145 mL and the left ventricular ejection fraction (LVEF) was (...)

28 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Subcutaneous implantable cardioverter-defibrillators: long-term results of the EFFORTLESS study - Lambiase P, Theuns D, Murgatroyd F, et al. Eur Heart J

AbstractAimsTo report 5-year outcomes of EFFORTLESS registry patients with early generation subcutaneous implantable cardioverter-defibrillator (S-ICD) devices.Methods and resultsKaplan–Meier, trend and multivariable analyses were performed for mortality and late (years 2–5) complications, (...)
01:00
Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics - Arbustini E, Behr E, Carrier L, et al. Eur Heart J

AbstractThis document describes the contribution of clinical criteria to the interpretation of genetic variants using heritable Mendelian cardiomyopathies as an example. The aim is to assist cardiologists in defining the clinical contribution to a genetic diagnosis and the interpretation of (...)
01:00
Association of transcatheter edge-to-edge repair with improved survival in older patients with severe, symptomatic degenerative mitral regurgitation - Benfari G, Sorajja P, Pedrazzini G, et al. Eur Heart J

AbstractBackgroundRandomized clinical trials demonstrated transcatheter edge-to-edge repair (TEER) efficacy in improving outcome vs. medical management for functional mitral regurgitation, but limited randomized data are available for the treatment of degenerative mitral regurgitation (DMR). We (...)

25 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Interferences with cardiac biomarker assays: understanding the clinical impact - Nevraumont A, Deltombe M, Favresse J, et al. Eur Heart J
01:00
Building a digital future together - Nicholls M. Eur Heart J

All correspondence relating to this paper should be sent to cardiopulseⓐunicatt.it
01:00
Preventing stroke in atrial fibrillation patients - Nicholls M. Eur Heart J

All correspondence relating to this paper should be sent to cardiopulseⓐunicatt.it
01:00
A fresh look at non-traditional risk factors: pregnancy loss, anger, ultra-processed food, and low ambient temperature - Crea F. Eur Heart J

24 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Artificial intelligence in cardiovascular medicine in China - Han Y. Eur Heart J

Artificial intelligence (AI) and digital health technologies have become of increasing interest in cardiovascular medicine due to their unique ability to improve the quality of patient care and leverage growing data to facilitate personalized and precision medicine.1,2 The potential of AI in (...)
01:00
Give genotype-guided dual antiplatelet therapy a second CHANCE - Liuzzo G, Patrono C. Eur Heart J

The results of ‘Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA’ have been published in the New England Journal of Medicine, https://doi.org/10.1056/NEJMoa2111749.

20 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial - Lehtisalo J, Rusanen M, Solomon A, et al. Eur Heart J

AbstractAimsJoint prevention of cardiovascular disease (CVD) and dementia could reduce the burden of both conditions. The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) demonstrated a beneficial effect on cognition (primary outcome) and we assessed (...)
01:00
Polypill for prevention of cardiovascular diseases with focus on non-alcoholic steatohepatitis: the PolyIran-Liver trial - Merat S, Jafari E, Radmard A, et al. Eur Heart J

AbstractAimsIndividuals with non-alcoholic steatohepatitis or elevated liver enzymes have increased cardiovascular mortality but are often excluded from prevention trials. We investigated the effectiveness of fixed-dose combination therapy for the prevention of major cardiovascular events (...)
01:00
Heparin use in acute coronary syndromes and cardiovascular interventions: habit or evidence based? - Tan S, White HD, Layland J. Eur Heart J

19 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Erratum to: CETP inhibitors revisited Eur Heart J

European Heart Journal, https://doi.org/10.1093/eurheartj/ehab889.

14 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Current recommendations and uncertainties for surgical treatment of infective endocarditis: a comparison of American and European cardiovascular guidelines - Wang A, Fosbøl E. Eur Heart J

AbstractSurgery is an effective therapy in the treatment of left-sided infective endocarditis (IE) in patients for whom antibiotic treatment alone is unlikely to be curative or may be associated with ongoing risk of complications. However, the interplay between indication for surgery, its risk, (...)
01:00
Cerebral protection device out of transcatheter heart procedures: a bridge to surgery - Calcagno S, Di Pietro R, Biondi-Zoccai G, et al. Eur Heart J
01:00
PCSK9 inhibition in patients with heart failure: neutral or harmful intervention? - Niessner A, Drexel H. Eur Heart J
01:00
Reduction of lipoprotein(a) with proprotein convertase subtilisin/kexin type 9 inhibitor as a potential contributor to modulating coronary inflammatory activity: insights from serial pericoronary adipose tissue analysis - Kitahara S, Kataoka Y, Miura H, et al. Eur Heart J

A 58-year-old gentleman with heterozygous familial hypercholesterolaemia was hospitalized due to stable angina pectoris. Coronary computed tomography angiography (CCTA) visualized severe stenotic lesion in his left anterior descending artery. Furthermore, a substantially high pericoronary (...)

13 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Hot topics in ischaemic heart disease: revascularization, hibernation, type 2 infarction, and proteomics - Crea F. Eur Heart J

12 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: Incidence, Risk Factors and Mortality of Atrial Fibrillation in Breast Cancer: A SEER-Medicare Analysis Eur Heart J

Corrigendum to: Incidence, risk factors, and mortality of atrial fibrillation in breast cancer: a SEER-Medicare analysis
01:00
Corrigendum to: A Phenomapping-Derived Tool to Personalise the Selection of Anatomical versus Functional Testing in Evaluating Chest Pain (ASSIST) Eur Heart J

Corrigendum to: A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST)
01:00
Corrigendum to: Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis Eur Heart J

Corrigendum to: Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis.

3 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
Current clinical data and experience of TAVR in China - Han Y. Eur Heart J

Yaling Han, Editor-in-Chief of the Chinese Journal of Cardiology (CJC), reviews two of the most remarkable papers published in the Journal.
01:00
The year in cardiovascular medicine 2021: valvular heart disease - Baumgartner H, Iung B, Messika-Zeitoun D, et al. Eur Heart J
01:00
The year in cardiovascular medicine 2021: heart failure and cardiomyopathies - Bauersachs J, de Boer RA, Lindenfeld J, et al. Eur Heart J

AbstractIn the year 2021, the universal definition and classification of heart failure (HF) was published that defines HF as a clinical syndrome with symptoms and/or signs caused by a cardiac abnormality and corroborated by elevated natriuretic peptide levels or objective evidence of (...)
01:00
The year in cardiovascular medicine 2021: interventional cardiology - Escaned J, Jaffer FA, Mehilli J, et al. Eur Heart J

AbstractSince last year’s report in the European Heart Journal, we have witnessed substantial progress in all aspects of interventional cardiology. Of note, the practice of interventional cardiology took place amidst successive waves of the COVID-19 pandemic, which continues to be a major burden (...)
01:00
The year in cardiovascular medicine 2021: diabetes and metabolic disorders - Cosentino F, Bhatt DL, Marx N, et al. Eur Heart J

AbstractIn the current paper, we review recently published studies that are helping us to understand how the treatment landscape for glucagon-like peptiide-1 receptor agonists and sodium glucose cotransporter 2 inhibitors is moving forward. We have also included relevant articles related to (...)
01:00
The year in cardiovascular medicine 2021: digital health and innovation - Vardas PE, Asselbergs FW, van Smeden M, et al. Eur Heart J

AbstractThis article presents some of the most important developments in the field of digital medicine that have appeared over the last 12 months and are related to cardiovascular medicine. The article consists of three main sections, as follows: (i) artificial intelligence-enabled (...)

1 January

Eur Heart J https://academic.oup.com/site_5375/

01:00
A comprehensive update on cardiovascular surgery: challenges and opportunities - Crea F. Eur Heart J

30 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Transcatheter closure of unroofed coronary sinus syndrome: a short-term result - Zhou Z, Gu Y, Zheng H. Eur Heart J

National Key Research and Development Program of China10.13039/5011000121662018YFB1107100
01:00
Genetic evidence for vitamin D and cardiovascular disease: choice of variants is critical - Burgess S, Gill D. Eur Heart J

28 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: Fall in the ATP levels in the red blood cells in ApoE-LDLR double-deficient mice model prior to atherosclerosis development - Alcicek F, Mohaissen T, Bulat K, et al. Eur Heart J

Eur Heart J 2021; https://doi.org/10.1093/eurheartj/ehab724.3400

22 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
PARADISE-MI suggests a limited role of intensified neuro-hormonal inhibition in the management of acute myocardial infarction with reduced ejection fraction - Liuzzo G, Volpe M. Eur Heart J

Comment on ‘Angiotensin receptor-neprilysin inhibition in acute myocardial infarction’ published in the New England Journal of Medicine https://doi.org/10.1056/NEJMoa2104508.

21 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Sodium–glucose co-transporter inhibitors, iron therapy, and checkpoint inhibitors: new clinical and translational pieces of the heart failure puzzle - Crea F. Eur Heart J

20 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: European Society of Cardiology guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1—epidemiology, pathophysiology, and diagnosis; and ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2—care pathways, treatment, and follow-up - . Eur Heart J

Eur Heart J 2021; https://doi.org/10.1093/eurheartj/ehab696 and https://doi.org/10.1093/eurheartj/ehab697

18 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Patient education, engagement, and empowerment: the time is now - Gatzoulis M, Grocott-Mason R. Eur Heart J

Times have changed. The English language and technology have made communication easier and the world a smaller place. Yet disease burden is rampant—and global—and expectations of a long and good life are high, as should be. Healthcare systems do their best to provide care, but with new therapies (...)
01:00
Alirocumab after acute coronary syndrome in patients with a history of heart failure - White H, Schwartz G, Szarek M, et al. Eur Heart J

AbstractAimsPatients with heart failure (HF) have not been shown to benefit from statins. In a post hoc analysis, we evaluated outcomes in ODYSSEY OUTCOMES in patients with vs. without a history of HF randomized to the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor alirocumab (...)
01:00
The ‘Ten Commandments’ of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure - Adamo M, Gardner R, McDonagh T, et al. Eur Heart J

The 10 main messages of the new guidelines for the diagnosis and treatment of acute and chronic heart failure (Figure 1) are:

16 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Comparative effects of guided vs. potent P2Y12 inhibitor therapy in acute coronary syndrome: a network meta-analysis of 61 898 patients from 15 randomized trials - Galli M, Benenati S, Franchi F, et al. Eur Heart J

AbstractAimsGuidelines recommend the use of potent P2Y12 inhibitors over clopidogrel for the reduction of ischaemic events in patients with acute coronary syndrome (ACS). However, this comes at the expense of increased bleeding. A guided selection of P2Y12 inhibiting therapy has the potential (...)
01:00
The CHADS-P2A2RC score: ready to guide the selection of treatment? - Mehilli J, Winhard M. Eur Heart J

Graphical AbstractGraphical AbstractRisk score models. *2 points, other factors only 1 point; CAD, coronary artery disease; CKD, chronic kidney disease; PAD, peripheral artery disease.

15 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Surgical whole valve embolization 15 years after implantation - Bedeir K, Robichaux R, Jr, Gleason T. Eur Heart J

A 38-year-old male with a mechanical aortic valve implanted 15 years ago for rheumatic disease presented to the hospital with sudden cardiopulmonary collapse. Upon arrival, he was in shock on high-dose pressors, intubated and mechanically ventilated. Chest radiograph revealed marked pulmonary (...)

14 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Nationwide collaboration produces valuable data regarding arch and descending aorta Eur Heart J
01:00
Multiorgan and vena cava perforation by an inferior vena cava filter: surgical approach and bovine pericardial patch reconstruction - Donato F, Boskoski I, Tinelli G, et al. Eur Heart J

A 64-year-old man with history of pulmonary embolism placed about 30 years back an inferior vena cava (IVC) filter. Computed tomography (CT) scan incidentally revealed the penetration of the IVC filter struts through the wall of the IVC and duodenum (Panel A). Esophagogastroduodenoscopy (EGD) (...)
01:00
The underrepresentation of female athletes in sports research: considerations for cardiovascular health - Zhu J, Reed J, Van Spall H. Eur Heart J

The proportion of female athletes in competitive sporting events—including the World Championships and Olympic games—has increased to nearly half of all athletes, and competing athletes increasingly include those who are peripartum. While participation in sports is closely implicated in (...)
01:00
Defining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement - Herrmann J, (Chair), Lenihan D, (Co-chair), Armenian S, et al. Eur Heart J

AbstractThe discipline of Cardio-Oncology has seen tremendous growth over the past decade. It is devoted to the cardiovascular (CV) care of the cancer patient, especially to the mitigation and management of CV complications or toxicities of cancer therapies, which can have profound implications (...)
01:00
An update on triglyceride-rich lipoproteins and their remnants in atherosclerotic cardiovascular disease - Crea F. Eur Heart J

13 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction - Nowroozpoor A, Sharp E, Gordon R, et al. Eur Heart J

Eur Heart J 2021; https://doi.org/10.1093/eurheartj/ehab724.2744
01:00
Immune cells in cardiac homeostasis and disease: emerging insights from novel technologies - Steffens S, Nahrendorf M, Madonna R. Eur Heart J

AbstractThe increasing use of single-cell immune profiling and advanced microscopic imaging technologies has deepened our understanding of the cardiac immune system, confirming that the heart contains a broad repertoire of innate and adaptive immune cells. Leucocytes found in the healthy heart (...)

9 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Predictors of long-term mortality among perioperative survivors of Fontan operation Eur Heart J

AbstractAimsThe criteria for ‘good’ Fontan haemodynamics have been poorly defined in relation to long-term outcomes. The aim of this study was to identify the risk factors for mortality among haemodynamic parameters obtained early after the Fontan operation.Methods and resultsClinical data of all (...)
01:00
Bringing FIDELITY to the estimate of treatment effects of finerenone in chronic kidney disease due to type 2 diabetes - Adamson C, Jhund P. Eur Heart J

Graphical AbstractGraphical AbstractBenefits of pooling trials of finerenone in chronic kidney disease.
01:00
Iron therapy on quality of life in acute heart failure: alternative approaches - Sawicki K, Ardehali H. Eur Heart J

National Institutes of Health (NIH)R01 HL127646R01 HL140973R01 HL138982
01:00
Dilemmas on diagnosis and treatment of iron deficiency in patients after an episode of acute heart failure - Jankowska E, Ponikowski P. Eur Heart J

This commentary refers to ‘The effect of intravenous ferric carboxymaltose on health-related quality of life in iron-deficient patients with acute heart failure: the results of the AFFIRM-AHF study’, by E.A. Jankowska et al., https://doi.org/10.1093/eurheartj/ehab234 and the discussion piece (...)

8 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Corrigendum to: AV junction ablation and cardiac resynchronization for patients with permanent atrial fibrillation and narrow QRS: the APAF-CRT mortality trial - Brignole M, Pentimalli F, Palmisano P, et al. Eur Heart J

Eur Heart J (2021); https://doi.org/10.1093/eurheartj/ehab569
01:00
Re-emergence of heart failure with a normal ejection fraction? - Kondo T, McMurray J. Eur Heart J

Graphical AbstractGraphical AbstractInteraction between the effect of: (A) the sodium–glucose co-transporter 2 (SGLT2) empagliflozin; from Butler et al.;6 and of (B) the angiotensin receptor blocker (ARB) candesartan; (C) the angiotensin receptor-neprilysin inhibitor (ARNI) sacubitril valsartan; (...)
01:00
Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction - Butler J, Packer M, Filippatos G, et al. Eur Heart J

AbstractAimsNo therapy has shown to reduce the risk of hospitalization for heart failure across the entire range of ejection fractions seen in clinical practice. We assessed the influence of ejection fraction on the effect of the sodium–glucose cotransporter 2 inhibitor empagliflozin on heart (...)

7 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Alert system-supported lay defibrillation and basic life-support for cardiac arrest at home - Stieglis R, Zijlstra J, Riedijk F, et al. Eur Heart J

AbstractAimsAutomated external defibrillators (AEDs) are placed in public, but the majority of out-of-hospital cardiac arrests (OHCA) occur at home.Methods and resultsIn residential areas, 785 AEDs were placed and 5735 volunteer responders were recruited. For suspected OHCA, dispatchers (...)
01:00
Atrial fibrillation and breast cancer: casual or causal relationship? - Merino J. Eur Heart J

Graphical AbstractGraphical AbstractCauses and factors potentially leading to atrial fibrillation (AF) in cancer patients and associated with thrombo-embolism (TE) or bleeding in both disorders. Factors shown in red are related to medical interventions. CTRCD, cancer therapy-related cardiac (...)
01:00
Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology, endorsed by the European Respiratory Society - Klok F, Ageno W, Ay C, et al. Eur Heart J

AbstractThis position paper provides a comprehensive guide for optimal follow-up of patients with acute pulmonary embolism (PE), covering multiple relevant aspects of patient counselling. It serves as a practical guide to treating patients with acute PE complementary to the formal 2019 European (...)
01:00
Management of arrhythmias: the increasing role of artificial intelligence, genetics and cardiac resyncronization - Crea F. Eur Heart J

6 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Dual antithrombotic treatment in chronic coronary syndrome: European Society of Cardiology criteria vs. CHADS-P2A2RC score - Würtz M, Olesen K, Mortensen M, et al. Eur Heart J

AbstractAimsAccording to the 2019 European Society of Cardiology (ESC) guidelines on chronic coronary syndromes (CCS), adding a P2Y12 inhibitor or rivaroxaban to aspirin should be considered in high-risk patients. We estimated the proportion of patients eligible for treatment with the ESC (...)
01:00
Respectful language and putting the person first with obesity - Bajaj S, Tu L, Stanford F. Eur Heart J

National Institutes of Health and Massachusetts General Hospital Executive Committee on Research
01:00
New EHJ Team on Thrombosis Eur Heart J

Thrombotic and bleeding events underlie many cardiovascular diseases and complications of invasive and medical therapies. Thrombosis pervades all medical fields, from cancer and infections to lung, brain, blood, and metabolic disorders. The new EHJ team on thrombosis has worked actively during (...)

5 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Non-linear Mendelian randomization analyses support a role for vitamin D deficiency in cardiovascular disease risk - Zhou A, Selvanayagam J, Hyppönen E. Eur Heart J

AbstractAimsLow vitamin D status is associated with a higher risk for cardiovascular diseases (CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null effect of vitamin D on CVD risk, a non-linear effect cannot be excluded. Our aim was to apply the non-linear (...)

4 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Acromegaly and cardiovascular outcomes: a cohort study - Hong S, Kim K, Han K, et al. Eur Heart J

AbstractAimsCardiovascular disease is a common complication in acromegaly. We investigated the risk of cardiovascular disease and mortality in patients with acromegaly in a large-scale population using nationwide data in Korea.Methods and resultsWe performed a nationwide, retrospective, (...)
01:00
Pandora will never regret having opened her box: reappraisal of genes associated with CPVT and SQTS - Horie M, Ohno S, Ai T. Eur Heart J
01:00
Investigating the disease is the key to the obesity stigma - Rayner J, Rider O. Eur Heart J

This commentary refers to ‘Obesity modifies the energetic phenotype of dilated cardiomyopathy’, by J.J. Rayner et al., https://doi.org/10.1093/eurheartj/ehab663 and the discussion piece ‘Respectful language and putting the person first with obesity’, by S.S. Bajaj, L. Tu and F.C. Stanford, (...)

2 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Pitfalls in recapture or repositioning of Evolut system using cusp overlap technique - Jang S, Chen Y, Shen T. Eur Heart J

An 89-year-old male with symptomatic severe aortic stenosis underwent transfemoral transcatheter aortic valve implantation. The pre-procedural computed tomography showed horizontal aorta along with heavy calcification of both right and non-coronary cusps (Panels A and B). We attempted to deploy (...)
01:00
Ultra-processed food consumption and disease: the jury is still out - Castro-Barquero S, Estruch R. Eur Heart J

This editorial refers to ‘Ultra-processed food intake and all-cause and cause-specific mortality in individuals with cardiovascular disease: the Moli-sani Study’, by M. Bonaccio et al., https://doi.org/10.1093/eurheartj/ehab783.

1 December

Eur Heart J https://academic.oup.com/site_5375/

01:00
Success at the double: two scientists scoop major award Eur Heart J

CardioPulse meets Giovanni G. Camici, PhD, and Paul Evans, PhD, the two scientists whose hard work and dedication has been recognized by the ESC Council on Basic Cardiovascular Science (CBCS) with the 2021 Outstanding Achievement Award. The annual award honours outstanding contribution and (...)
01:00
The untapped potential of reproductive history in cardiovascular disease - Bliddal S, Westergaard D, Nielsen H. Eur Heart J

Graphical AbstractGraphical AbstractWomen suffering a pregnancy loss have a significantly higher risk of developing cardiovascular disease later in life. Identifying the unknown biological mechanism(s) behind this association can help us understand disease initiation and progression at an early (...)
01:00
The ‘ten commandments’ for the 2021 ESC Guidelines on CVD prevention - Carballo D, Visseren F, Mach F, et al. Eur Heart J

The 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice have now been published, updating the 2016 edition.1 The publication of these guidelines coincides with a decrease in atherosclerotic cardiovascular disease (ASCVD) mortality rates in Europe. However, as stated in (...)
01:00
Triggers of stroke: anger, emotional upset, and heavy physical exertion. New insights from the INTERSTROKE study - Wegener S. Eur Heart J

Graphical AbstractGraphical AbstractNegative emotions and physical exertion may trigger stroke.
01:00
Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study - Smyth A, O’Donnell M, Hankey G, et al. Eur Heart J

AbstractAimsIn INTERSTROKE, we explored the association of anger or emotional upset and heavy physical exertion with acute stroke, to determine the importance of triggers in a large, international population.Methods and resultsINTERSTROKE was a case–control study of first stroke in 32 countries. (...)
01:00
Percutaneous coronary interventions: more complex than fixing stenoses - Crea F. Eur Heart J

30 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Age-independent benefits of blood pressure lowering: are they applicable to all patients? - Volpe M, Patrono C. Eur Heart J

Comment on ‘Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis’ published in The Lancet (...)
01:00
Therapeutic-dose heparin should integrate the standard of care of moderately ill patients with COVID-19 admitted to hospital - Liuzzo G, Patrono C. Eur Heart J

Comment on ‘Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial’ published in the British Medical Journal (...)
01:00
Ultra-processed food intake and all-cause and cause-specific mortality in individuals with cardiovascular disease: the Moli-sani Study - Bonaccio M, Costanzo S, Di Castelnuovo A, et al. Eur Heart J

AbstractAimsTo evaluate the association of ultra-processed food (UPF) intake and mortality among individuals with history of cardiovascular disease (CVD) and analyse some biological pathways possibly relating UPF intake to death.Methods and resultsLongitudinal analysis on 1171 men and women (...)

29 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study Eur Heart J

AbstractAimsTo observe, describe, and evaluate management and timing of intervention for patients with untreated thoracic aortic aneurysms.Methods and resultsProspective study of UK National Health Service (NHS) patients aged ?18 years, with new/existing arch or descending thoracic aortic (...)
01:00
Cardiology Update India 21: a growing Indio-European educational platform to fight cardiovascular disease - Ram V, Amstein R, Lüscher T. Eur Heart J
01:00
Ambient temperature and aortic dissection: do pipes burst in freezing weather? - Hibino M, Yanagawa B, Pandey A, et al. Eur Heart J

Graphical AbstractGraphical AbstractAortic dissection, ambient temperature, and their possible association.

28 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Aortic stenosis management in 2021: better teaming up than fighting between specialties - Baumgartner H. Eur Heart J

Graphical AbstractGraphical AbstractManagement of severe symptomatic aortic stenosis over the decades. Left upper panel: 1980–1990. Valve replacement reverses the dismal outcome of severe symptomatic AS (adapted from Horstkotte and Loogen3). Right upper panel: 1990–2000. Many patients do not (...)
01:00
Low ambient temperature and temperature drop between neighbouring days and acute aortic dissection: a case-crossover study - Chen J, Gao Y, Jiang Y, et al. Eur Heart J

AbstractAimsThe incidence of acute aortic dissection (AAD) has been shown to have seasonal variation, but whether this variation can be explained by non-optimum ambient temperature and temperature change between neighbouring days (TCN) is not clear.Methods and resultsWe performed a (...)

26 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Importance of sex and gender in ischaemic stroke and carotid atherosclerotic disease - Gasbarrino K, Di Iorio D, Daskalopoulou S. Eur Heart J

AbstractStroke is a leading cause of death and disability worldwide. Women are disproportionately affected by stroke, exhibiting higher mortality and disability rates post-stroke than men. Clinical stroke research has historically included mostly men and studies were not properly designed to (...)

25 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy - Kraler S, Blaser M, Aikawa E, et al. Eur Heart J

AbstractCalcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling, culminating in aortic stenosis, heart failure, and ultimately premature death. Traditional risk (...)
01:00
Trends in aortic valve replacement for aortic stenosis: a French nationwide study - Nguyen V, Willner N, Eltchaninoff H, et al. Eur Heart J

AbstractAimsTranscatheter aortic valve replacement (TAVR) as an alternative to surgical aortic valve replacement (SAVR) has profoundly changed the management of patients with aortic valve stenosis (AS). Large unbiased nationwide data regarding TAVR implementation, impact on SAVR and their (...)
01:00
A new tool for the forgotten valve: a score to predict the risk of surgery - Colombo A, Maisano F. Eur Heart J

Graphical AbstractGraphical AbstractProposed algorithm for decision-making in patients with isolated tricuspid regurgitation.

24 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Electrical alternans detected by an Apple Watch - Carrión-Sánchez I, Cobos-Gil M. Eur Heart J

A 63-year old man with a history of metastatic lung cancer complained of exercise dyspnoea in the last month.
01:00
Coronary flow reserve and cardiovascular outcomes: a systematic review and meta-analysis - Kelshiker M, Seligman H, Howard J, et al. Eur Heart J

AbstractAimsThis meta-analysis aims to quantify the association of reduced coronary flow with all-cause mortality and major adverse cardiovascular events (MACE) across a broad range of patient groups and pathologies.Methods and resultsWe systematically identified all studies between 1 January (...)
01:00
Myocardial infarction after elective percutaneous coronary intervention—which cardiac troponin cut-off to use? - Eggers K, James S, Lindahl B. Eur Heart J

This commentary refers to ‘Procedural myocardial injury, infarction and mortality in patients undergoing elective PCI: a pooled analysis of patient-level data’, by J. Silvain et al., https://doi.org/10.1093/eurheartj/ehaa885 and the discussion piece ‘Appropriate criteria for the definition of Type (...)
01:00
Appropriate criteria for the definition of Type 4a MI - Silvain J, Hausenloy D, Zeitouni M. Eur Heart J

This commentary refers to ‘Procedural myocardial injury, infarction and mortality in patients undergoing elective PCI: a pooled analysis of patient-level data’, by J. Silvain et al., https://doi.org/10.1093/eurheartj/ehaa885 and the discussion piece ‘Myocardial infarction after elective (...)
01:00
Vascular repair and regeneration in cardiometabolic diseases - Hess D, Verma S, Bhatt D, et al. Eur Heart J

AbstractChronic cardiometabolic assaults during type 2 diabetes (T2D) and obesity induce a progenitor cell imbalance in the circulation characterized by overproduction and release of pro-inflammatory monocytes and granulocytes from the bone marrow alongside aberrant differentiation and (...)
01:00
Implantable recorders and systematic atrial fibrillation detection do not outperform standard of care in stroke prevention in the LOOP study - Narducci M, Volpe M. Eur Heart J

Key PointsAtrial Fibrillation (AFib) Detected by Continuous ECG Monitoring Using Implantable Loop Recorder to Prevent Stroke in High-risk Individuals (the LOOP study) was an investigator-initiated, multicentre, unblinded, randomised controlled trial, partially funded by industry, carried out to (...)

22 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
The Atrial Fibrillation Heart Team—guiding therapy in left atrial appendage occlusion with increasingly complex patients and little evidence - Kany S, Metzner A, Lubos E, et al. Eur Heart J

European Union BigDataⓐHeartEU IMI 116074British Heart Foundation10.13039/501100000274FS/13/43/30324PG/17/30/32961PG/20/22/35093AA/18/2/34218German Centre for Cardiovascular Research10.13039/100010447German Ministry of Education and ResearchDZHK e.V., 81Z1710103Leducq (...)
01:00
Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis - Agarwal R, Filippatos G, Pitt B, et al. Eur Heart J

AbstractAimsThe complementary studies FIDELIO-DKD and FIGARO-DKD in patients with type 2 diabetes and chronic kidney disease (CKD) examined cardiovascular and kidney outcomes in different, overlapping stages of CKD. The purpose of the FIDELITY analysis was to perform an individual patient-level (...)

21 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
How epidemiology can improve the understanding of cardiovascular disease: from mechanisms to treatment - Crea F. Eur Heart J

18 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Extreme cardiovascular risk—do we need a new risk category? - Dyrbu? K, G?sior M, Penson P, et al. Eur Heart J

17 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Strengthening cardiovascular trials across Australia and New Zealand—the Alliance for Cardiovascular Trials (ANZACT) Network - Reid C, Patel A, Nicholls S, et al. Eur Heart J

National Health and Medical Research Council Centre of Research Excellence in Cardiovascular Outcomes ImprovementGNT111170
01:00
SCORE2 models allow consideration of sex-specific cardiovascular disease risks by region - Hageman S, Pennells L, Ojeda F, et al. Eur Heart J

This commentary refers to ‘SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe’, by the SCORE2 working group and European Society of Cardiology (ESC) Cardiovascular Risk Collaboration, https://doi.org/10.1093/eurheartj/ehab309 and the (...)
01:00
VANISHing the progression of cardiac abnormalities in hypertrophic cardiomyopathy with early use of valsartan? - Volpe M, Liuzzo G. Eur Heart J

Key PointsThe VANISH trial1 was a multi-centre (17 sites in four countries), double-blind, placebo-controlled phase-2 trial that analysed the effects of the angiotensin II receptor blocker (ARB), valsartan, in subjects with early-stage hypertrophic cardiomyopathy (HCM). From April 2014 to May (...)
01:00
A sex-specific prediction model is not enough to achieve equality for women in preventative cardiovascular medicine - Kimenai D, Shah A, Mills N. Eur Heart J

Health Data Research UKUK Medical Research Council10.13039/501100000265Engineering and Physical Sciences Research Council10.13039/501100000266Economic and Social Research Council10.13039/501100000269Department of Health and Social Care (England)Chief Scientist Office of the Scottish Government (...)
01:00
A new biomarker of acute coronary ischaemia: from bench to bedside? - Newby L. Eur Heart J

Graphical AbstractGraphical AbstractBridging the gap from bench to bedside in biomarker development.

14 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Incidence, risk factors, and mortality of atrial fibrillation in breast cancer: a SEER-Medicare analysis - Guha A, Fradley M, Dent S, et al. Eur Heart J

AbstractAimsThe national incidence, risk factors, and associated mortality of atrial fibrillation (AF) in breast cancer patients are unknown.Methods and resultsUsing the Surveillance, Epidemiology, and End Results-Medicare-linked database, we identified females, ?66 years old, with a new primary (...)
01:00
Mechanisms of heart failure with preserved ejection fraction, risk stratification of heart failure with reduced ejection fraction, and new light on resistance to diuretics in acute decompensated heart failure - Crea F. Eur Heart J

13 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Myocardial viability testing: all STICHed up, or about to be REVIVED? - Ryan M, Morgan H, Chiribiri A, et al. Eur Heart J

AbstractPatients with ischaemic left ventricular dysfunction frequently undergo myocardial viability testing. The historical model presumes that those who have extensive areas of dysfunctional-yet-viable myocardium derive particular benefit from revascularization, whilst those without extensive (...)

11 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Computed tomography coronary angiography in acute chest pain: an excellent diagnostic tool with poor added value on clinical outcomes - Liuzzo G, Volpe M. Eur Heart J

Key PointsThe RAPID-CTCA1 is a prospective, randomized, open-label, blinded endpoint assessment, parallel group, clinical effectiveness trial in 37 hospitals across the United Kingdom, investigating whether early computed tomography coronary angiography (CTCA) may influence the management and (...)
01:00
Echocardiography for risk stratification in patients with pulmonary embolism at low risk of death: a response - Maraziti G, Vinson D, Becattini C. Eur Heart J

This commentary refers to ‘Right ventricle assessment in patients with pulmonary embolism at low risk for death based on clinical models: an individual patient data meta-analysis’, by C. Becattini et al., https://doi.org/10.1093/eurheartj/ehab329 and the discussion piece ‘Right ventricle (...)
01:00
A fixed-dose combination treatment strategy to reduce premature cardiovascular disease deaths globally - Liuzzo G, Patrono C. Eur Heart J

Key PointsAn individual participant data (IPD) meta-analysis of large, randomized, controlled trials compared the efficacy and safety of a fixed-dose combination strategy of ?2 blood pressure (BP)-lowering agents plus a statin (with or without aspirin) versus control (placebo or usual care) in a (...)
01:00
Right ventricle assessment in patients with pulmonary embolism: low risk = low yield for systematic echocardiography - Arrigo M, Huber L. Eur Heart J

This commentary refers to ‘Right ventricle assessment in patients with pulmonary embolism at low risk for death based on clinical models: an individual patient data meta-analysis’, by C. Becattini et al., https://doi.org/10.1093/eurheartj/ehab329 and the discussion piece ‘Echocardiography for risk (...)

10 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
‘Targeting the cardiac myocyte and fibrosis’ in heart failure - Ishiura J, Nakamori S, Ishida M, et al. Eur Heart J

A previously healthy 38-year-old man was referred to our cardiology department with exertional dyspnoea. Echocardiography demonstrated left ventricular (LV) dilatation and global systolic dysfunction with normal wall thickness (Panel A and Supplementary material onlineSupplementary material (...)

9 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Opening a new window on cardiovascular research - Nicholls M. Eur Heart J

All correspondence relating to this paper should be sent to: cardiopulseⓐunicatt.it
01:00
Saving two hearts at once: How the 2014 ESC Congress inspired a revolution in maternal health in Iraq? - Ozkan J. Eur Heart J

All correspondence relating to this paper should be sent to: cardiopulseⓐunicatt.it
01:00
Implementation science and potential for screening in heart failure - Lund L, Hage C, Savarese G. Eur Heart J

Graphical AbstractGraphical AbstractProposed conceptual framework for HF care and HF needs according to EF category (HFrEF, HFmrEF, or HFpEF) and level of care (HF referral centre, general cardiology or internal medicine, or primary (...)

8 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Effect of 5 years of exercise training on the cardiovascular risk profile of older adults: the Generation 100 randomized trial - Letnes J, Berglund I, Johnson K, et al. Eur Heart J

AbstractAimsThe aim of this study was to compare the effects of 5 years of supervised exercise training (ExComb), and the differential effects of subgroups of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), with control on the cardiovascular risk (...)

7 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
New targets in vascular biology and new challenges in vascular medicine - Crea F. Eur Heart J

5 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Diverse topics tackled by latest ‘hot’ research - Nicholls M. Eur Heart J

Extensive research was presented across a range of specialist areas in 20 Hot Line Sessions at ESC Congress 2021, including heart failure, stroke, atrial fibrillation, implantable cardiac monitors, intensive blood pressure lowering, dual anti-platelet therapy, and risk reduction for (...)

3 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Pneumopericardium mimicking ST-segment elevation acute coronary syndrome - Fernández Asensio R, Pascual Calleja I, Moris de la Tassa C, et al. Eur Heart J

An 80-year-old man was admitted to the cardiac catheterization laboratory for an emergent diagnostic coronary angiography. The patient has been complaining of intermittent chest pain for two days and he was transferred to our centre with the suspicion of ST-segment elevation acute coronary (...)
01:00
Mineral oil and icosapent ethyl may jointly explain the between arm difference of cardiovascular risk in REDUCE-IT - Doi T, Langsted A, Nordestgaard B. Eur Heart J

This commentary refers to ‘A possible explanation for the contrasting results of REDUCE-IT vs. STRENGTH: cohort study mimicking trial designs’, by T. Doi, https://doi.org/10.1093/eurheartj/ehab555 and the discussion piece ‘The reduction in cardiovascular risk in REDUCE-IT is due to (...)
01:00
The reduction in cardiovascular risk in REDUCE-IT is due to eicosapentaenoic acid in icosapent ethyl - Steg P, Bhatt D. Eur Heart J

This commentary refers to ‘A possible explanation for the contrasting results of REDUCE-IT vs. STRENGTH: cohort study mimicking trial designs’, by T. Doi et al., https://doi.org/10.1093/eurheartj/ehab555 and the discussion piece ‘Mineral oil and icosapent ethyl may jointly explain the between arm (...)

2 November

Eur Heart J https://academic.oup.com/site_5375/

01:00
Strengths and limitations of meta-analyses - Berry C. Eur Heart J

British Heart Foundation10.13039/501100000274PG/17/2532884FS/17/26/32744RE/18/6134217
01:00
Reporting data from meta-analysis: snapshot of a moving target - Ahmad Y, Howard J, Madhavan M, et al. Eur Heart J

This commentary refers to ‘Meta-analyses of moving targets’, by C. Berry, https://doi.org/10.1093/eurheartj/ehab359; and the discussion piece ‘Strengths and limitations of meta-analyses’, by C. Berry, https://doi.org/10.1093/eurheartj/ehab682.

31 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Welcome on board! Meet the new EHJ board reviewers Eur Heart J

In August 2021, the EHJ welcomed a talented and skilled new group of Board Reviewers from a diverse range of countries and backgrounds who will bring their own perspective and expertise to the journal. CardioPulse is delighted to present the new (...)

30 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Sodium glucose co-transporter inhibitors and heart failure outcomes across different patient populations - Butler J, Anker S, Filippatos G, et al. Eur Heart J

28 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
ESC/HFA Quality of Care Centres: the ultimate frontier in unifying heart failure management - Seferovic P, Piepoli M, Polovina M, et al. Eur Heart J

Heart failure (HF) is a major public health concern and a leading global cause of mortality, hospitalization, disability, and high associated healthcare costs. According to the recent Heart Failure Association of the ESC (HFA) Atlas survey of the 42 European Society of Cardiology (ESC) member (...)
02:00
Meet the winner of the first annual Desmond Julian Award - Ozkan J. Eur Heart J

A new initiative to recognize excellence and innovation for an outstanding paper published in the European Heart Journal (EHJ) has rewarded a Netherlands-based research scientist for his contribution to a widely acclaimed manuscript written during the (...)

27 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Pregnancy loss and risk of cardiovascular disease: the Nurses’ Health Study II - Wang Y, Mínguez-Alarcón L, Gaskins A, et al. Eur Heart J

AbstractAimsThe aim of this study was to explore the association of pregnancy loss (PL) with the incidence of cardiovascular disease (CVD) and examine the extent to which this relation is mediated by subsequent metabolic disorders.Methods and resultsWe followed 95 465 ever-gravid women (...)

25 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
ESC and EHRA lead a path towards integrated care for multimorbid atrial fibrillation patients: the Horizon 2020 EHRA-PATHS project - Heidbuchel H, Van Gelder I, Desteghe L, et al. Eur Heart J

European Union’s Horizon 2020 research and innovation programme945260
02:00
PCSK9 inhibition for acute arterial events: more than LDL lowering - Orringer C. Eur Heart J

24 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Wine, chocolate, and coffee: forbidden joys? - Lüscher T. Eur Heart J

23 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Thrombosis and fibrinolysis in atherosclerotic cardiovascular disease: it takes two to tango - Fedorowski A, Siller-Matula J, Patti G. Eur Heart J

Graphical AbstractGraphical AbstractProthrombotic and profibrinolytic marker groups as proposed by DeFilippis et al.3 with addition of other proposed markers of increased prothrombotic risk. When the balance between the prothrombotic (red) and profibrinolytic group (green) is shifted to the (...)
02:00
The promise of the gut metabolite propionate for a novel and personalized lipid-lowering treatment - Osto E. Eur Heart J

Graphical AbstractGraphical AbstractNovel insights and open questions about the anti-atherosclerotic actions of propionate through immune-dependent regulation of intestinal cholesterol metabolism; adapted from Haghikia et al.11
02:00
The Cornelian dilemma† of quitting DAPT - Motovska Z, Montalescot G. Eur Heart J

20 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Quadruple combination of quarter doses of blood pressure-lowering agents: a string QUARTET in the symphony of hypertension management? - Volpe M, Patrono C. Eur Heart J

Comment on ‘Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double blind, active-controlled trial’ published in The Lancet (...)

19 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Early diagnosis of cardiac allograft vasculopathy: biopsy, liquid biopsy, non-invasive imaging, coronary imaging, or coronary physiology? - Alfonso F, Rivero F, Segovia-Cubero J. Eur Heart J
02:00
Prognostic value of comprehensive intracoronary physiology assessment early after heart transplantation - Ahn J, Zimmermann F, Arora S, et al. Eur Heart J

AbstractAimsWe evaluated the long-term prognostic value of invasively assessing coronary physiology after heart transplantation in a large multicentre registry.Methods and resultsComprehensive intracoronary physiology assessment measuring fractional flow reserve (FFR), the index of (...)

18 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Reaching the stars - Nicholls M. Eur Heart J

All correspondence relating to this paper should be sent to: cardiopulseⓐunicatt.it
02:00
Early cardiac magnetic resonance leads to diagnose the etiology of myocardial infarction with non-obstructive coronary arteries - Tsuda K, Kanzaki Y, Hoshiga M. Eur Heart J

A 56-year-old man who developed chest discomfort was referred to our hospital. He had no history of prior cardiac disease and allergies. The electrocardiogram revealed no ST-segment change. Echocardiogram demonstrated mildly reduced left ventricular ejection fraction with diffuse hypertrophy (...)
02:00
FIGARO-DKD adds new evidence to the cardiovascular benefits of finerenone across the spectrum of patients with type 2 diabetes and chronic kidney disease - Liuzzo G, Volpe M. Eur Heart J

Comment on ‘Cardiovascular events with finerenone in kidney disease and type 2 diabetes’ published in the New England Journal of Medicine (https://doi.org/10.1056/NEJMoa2110956). The results of FIGARO-DKD trial were simultaneously presented at ESC Congress (...)
02:00
Ticagrelor monotherapy in patients at high bleeding risk undergoing percutaneous coronary intervention: TWILIGHT-HBR - Escaned J, Cao D, Baber U, et al. Eur Heart J

AbstractAimsPatients at high bleeding risk (HBR) represent a prevalent subgroup among those undergoing percutaneous coronary intervention (PCI). Early aspirin discontinuation after a short course of dual antiplatelet therapy (DAPT) has emerged as a bleeding avoidance strategy. The aim of this (...)

16 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Corrigendum to: Antiplatelet therapy in patients with conservatively managed spontaneous coronary artery dissection from the multicentre DISCO registry - Cerrato E, , Giacobbe F, et al. Eur Heart J

Eur Heart J 2021;42:3161–3171; doi:10.1093/eurheartj/ehab372.
02:00
Corrigendum to: AV junction ablation and cardiac resynchronization for patients with permanent atrial fibrillation and narrow QRS: the APAF-CRT mortality trial - Brignole M, , Pentimalli F, et al. Eur Heart J

Eur Heart J 2021; doi:10.1093/eurheartj/ehab569

14 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
When the solution becomes the problem: left atrial appendage occlusion device-related thrombus after 5 years - Nasser R, Meyten N, Vermeersch P, et al. Eur Heart J

An 85-year-old man presented to the neurology department due to an acute ischaemic stroke in the left frontal and parietal area (Panel A). Five years before, left atrial appendage (LAA) occlusion with a Watchman device was performed due to paroxysmal atrial fibrillation, multiple ischaemic (...)
02:00
Ciraparantag as a potential universal anticoagulant reversal agent - Chan N, Weitz J. Eur Heart J

This editorial refers to ‘Ciraparantag reverses the anticoagulant activity of apixaban and rivaroxaban in healthy elderly subjects’ by J. Ansell et al., doi:10.1093/eurheartj/ehab637.
02:00
Corrigendum to: 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC - McDonagh T, , Metra M, et al. Eur Heart J

In the originally published version of this manuscript, there were multiple errors in formatting and content. Figures 1, 2, 4, 5, 6, 12, 19, and 20 have been replaced with corrected versions. The wording of the recommendation "Tafamidis is recommended in patients with genetic testing proven (...)

12 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
A tribute to Attilio Maseri - Crea F, Braunwald E, Fuster V. Eur Heart J

A native of Udine in Northeastern Italy, Prof. Attilio Maseri graduated from the University of Padua Medical School in 1960 and immediately moved to Pisa, where he trained in Cardiology (1963) and Nuclear Medicine (1968). During this period, he served Research Fellowships at Columbia University (...)

11 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Myocardial revascularization in ischaemic cardiomyopathy: routine practice vs. scientific evidence - De Caterina R, Liga R, Boden W. Eur Heart J
02:00
Another STEP towards tighter control of blood pressure in the elderly - Volpe M, Patrono C. Eur Heart J

Key PointsThe STEP (Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients) trial1 is a multicentre, randomized, controlled study sponsored by FuWai Hospital and the Chinese Academy of Medical Sciences, conducted in Chinese hypertensive patients aged between 60 and 80 (...)
02:00
Don’t count the steps: make the steps count? Digging deeper into physical activity and fitness - Letnes J, Nes B. Eur Heart J

8 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Towards personalized antithrombotic management with drugs and devices across the cardiovascular spectrum - Lüscher T, Davies A, Beer J, et al. Eur Heart J

AbstractIntravascular thrombus formation and embolization are among the most frequent events leading to a number of cardiovascular conditions with high morbidity and mortality. The underlying causes are stasis of the circulating blood, genetic and acquired coagulation disorders, and reduced (...)
02:00
Immune checkpoint inhibitors and cardiovascular events among patients with cancer: a window into the critical role of the immune system in cardiovascular biology - Kondapalli L, Neilan T. Eur Heart J
02:00
Myocardial microthrombi after COVID-19 mRNA vaccination - Aikawa T, Ogino J, Kita Y, et al. Eur Heart J

JSPS10.13039/50110000169119K17189Fukuda Foundation for Medical Technology10.13039/501100003348Akiyama Life Science Foundation10.13039/100007591Northern Advancement Center for Science & Technology of Hokkaido Japan

7 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
CardioMetabolic medicine, one more last step forward - Carbone F. Eur Heart J

Since the concept of metabolic syndrome (MetS) was firstly formalized by Professor Reaven in 1988, insulin resistance was identified as the underlying common factor driving the associated cardiovascular (CV) risk. Ten years later the World Health Organization attempted to provide a (...)
02:00
The European Cardiac Arrhythmia Genetics (ECGen) Focus Group - Remme C, Leclercq C, Behr E. Eur Heart J
02:00
ESC 2021 named lectures: science, research, and innovation - Nicholls M. Eur Heart J

All correspondence relating to this paper should be sent to: cardiopulseⓐunicatt.it
02:00
William Harvey in quarantine and lazaretto when back to Italy at the time of 1630 plague - Marrone D, Basso C, Thiene G. Eur Heart J

Registry of Cardiovascular PathologyARCA Foundation
02:00
Gout, urate-lowering drugs, and risk of cardiovascular disease: can we clinically trust in the adjusted real-life data? - Borghi C, Fiorini G. Eur Heart J

6 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Pace and ablate better than drugs in patients with heart failure and atrial fibrillation: lessons from the APAF-CRT mortality trial - Linde C. Eur Heart J

2 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Risk factors for type 2 MI: the usual suspects or guilt by association? - O’Donoghue M, Marston N. Eur Heart J

This editorial refers to ‘Risk factors for type 1 and type 2 myocardial infarction’, by R. Wereski et al., doi:10.1093/eurheartj/ehab581.
02:00
Acute type A aortic dissection reconsidered: it’s all about the location of the primary entry tear and the presence or absence of malperfusion - Czerny M, Rylski B. Eur Heart J
02:00
Investigating contrasting results in REDUCE-IT and STRENGTH: partial answers but questions remain - Maki K. Eur Heart J

1 October

Eur Heart J https://academic.oup.com/site_5375/

02:00
Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism - Haghikia A, Zimmermann F, Schumann P, et al. Eur Heart J

AbstractAimsAtherosclerotic cardiovascular disease (ACVD) is a major cause of mortality and morbidity worldwide, and increased low-density lipoproteins (LDLs) play a critical role in development and progression of atherosclerosis. Here, we examined for the first time gut immunomodulatory (...)
02:00
The EMPEROR-Preserved study: end of the search for the “Phoenix” or beginning of a new season for trials in heart failure with preserved ejection fraction - Volpe M, Patrono C. Eur Heart J

Comment on ‘Empagliflozin in heart failure with a preserved ejection fraction’ published in the New England Journal of Medicine (DOI: 10.1056/NEJMoa2107038).
02:00
Vascular rejuvenation: a new therapeutic target? - Madonna R. Eur Heart J

Ministero dell’Istruzione, Università e Ricerca Scientifica549901_2020_Madonna

30 September

Eur Heart J https://academic.oup.com/site_5375/

02:00
Alcohol intake and risk of stroke in atrial fibrillation: the lesser the better, but this is not enough - Russo A. Eur Heart J

29 September

Eur Heart J https://academic.oup.com/site_5375/

02:00
TRI-SCORE: a new risk score for in-hospital mortality prediction after isolated tricuspid valve surgery - Dreyfus J, Audureau E, Bohbot Y, et al. Eur Heart J

AbstractAims Isolated tricuspid valve surgery (ITVS) is considered to be a high-risk procedure, but in-hospital mortality is markedly variable. This study sought to develop a dedicated risk score model to predict the outcome of patients after ITVS for severe tricuspid regurgitation (TR).Methods (...)

Articles récents

Préférences

Sources

Accueil du site

permalink

1 July

21 June

14 June

6 June

1 June

20 May

14 May

13 May

7 May

6 May

5 May

3 May

1 May

28 April

25 April

22 April

20 April

19 April

14 April

13 April

11 April

8 April

7 April

6 April

5 April

1 April

30 March

24 March

23 March

22 March

19 March

18 March

17 March

16 March

11 March

10 March

9 March

8 March

7 March

5 March

4 March

3 March

2 March

1 March

25 February

23 February

22 February

21 February

18 February

17 February

15 February

12 February

11 February

10 February

9 February

8 February

4 February

3 February

1 February

31 January

29 January

28 January

25 January

24 January

20 January

19 January

14 January

13 January

12 January

3 January

1 January

30 December