21 January

J Am Soc Nephrol https://jasn.asnjournals.org/

• 07:00
  Gut Dysbiosis in Experimental Kidney Disease: A Meta-Analysis of Rodent Repository Data - Randall, David W; Kieswich, Julius; Hoyles, Lesley; McCafferty, Kieran; Curtis, Michael; Yaqoob, Muhammed M J Am Soc Nephrol
  Background Rodent studies have popularized the notion that uremia may induce pathologic changes in the gut microbiota that contribute to kidney disease progression. Although single-cohort rodent studies have yielded insights into host-microbiota relationships in various disease processes, their (...) -- Meta-analysis - Chronic Kidney Disease
• 07:00
  Prevalence of Self-reported Kidney Disease in Older Adults by Sexual Orientation: Behavioral Risk Factor Surveillance System Analysis (2014-2019) - Chandra, Meghana; Hertel, Mollie; Cahill, Sean; Sakaguchi, Kevin; Khanna, Saumya; Mitra, Shimontini; Luke, Jordi; Khau, Meagan; Mirabella, Jack; Cropper, Avareena J Am Soc Nephrol
  Background: Existing research documents disparities in chronic kidney disease (CKD) by age, race/ethnicity, and access to health care. However, research on CKD in LGBT+ older adults, despite their higher rates of diabetes, heart disease, smoking, and alcohol use, is limited Methods: Pooled data (...) -- Clinical Research - Chronic Kidney Disease
• 07:00
  Protein Carbamylation and the Risk of End-Stage Kidney Disease in Patients with Chronic Kidney Disease - Kalim, Sahir; Zhao, Sophia; Tang, Mengyao; Rhee, Eugene P.; Allegretti, Andrew S.; Nigwekar, Sagar; Karumanchi, S. Ananth; Lash, James P.; Berg, Anders H. J Am Soc Nephrol
  Background Protein carbamylation, a posttranslational protein modification partially driven by elevated blood urea levels, associates with adverse outcomes in end-stage kidney disease (ESKD). However, little is known about protein carbamylation’s relationship to clinical outcomes in the much (...) -- Clinical Research - Chronic Kidney Disease
• 07:00
  Hyperactivation of YAP/TAZ Drives Alterations in Mesangial Cells through Stabilization of N-Myc in Diabetic Nephropathy - Choi, Seunghyeok; Hong, Seon Pyo; Bae, Jung Hyun; Suh, Sang Heon; Bae, Hosung; Kang, Kyung Pyo; Lee, Hyuek Jong; Koh, Gou Young J Am Soc Nephrol
  Background: Mesangial cells (MCs) in the kidney are central to maintaining glomerular integrity, and their impairment leads to major glomerular diseases including diabetic nephropathy (DN). Although high blood glucose elicits abnormal alterations in MCs, the underlying molecular mechanism is (...) -- Basic Research - Chronic Kidney Disease